Vitamin E
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| Nonfatal MI | |
|---|---|
| Vitamin E 800 IU/day | 2.0% (11/546) |
| Vitamin E 400 IU/day | 0.6% (3/489) |
| Placebo | 4.2% (41/967) |
In biochemistry, vitamin E is a "generic descriptor for all tocopherols and tocotrienols that exhibit alpha-tocopherol activity. by virtue of the phenolic hydrogen on the 2h-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of isoprenoids."[2]
In 2005, a meta-analysis concluded that Vitamin E supplementation may actually be harmful when used for the prevention of vascular disease.[3]
References
- ↑ Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K, Mitchinson MJ (March 1996). "Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)". Lancet 347 (9004): 781–6. DOI:10.1016/S0140-6736(96)90866-1. PMID 8622332. Research Blogging.
- ↑ Anonymous (2024), Vitamin E (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Miller ER, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E (January 2005). "Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality". Ann. Intern. Med. 142 (1): 37–46. PMID 15537682. [e]