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- '''Cytochrome P-450''' is a "superfamily of hundreds of closely related hemeproteins found thro Cytochrome P-450's role in drug metabolism is described by Wolf:<ref name="pmid10723863">{{c22 KB (2,960 words) - 17:35, 10 February 2024
- In [[biology]], the '''cytochrome P-450 CYP2D6''' is a "[[cytochrome P-450]] enzyme that catalyzes the hydroxylation of many drugs and environmental c ...due to inhibiting metabolism of [[tamoxifen]] to its active metabolite by cytochrome P-450 CYP2D6.<ref>{{Cite journal | doi = 10.1136/bmj.c693 | volume = 340 | issue3 KB (483 words) - 17:34, 10 February 2024
- ...84">{{cite journal |author=Mega JL, Close SL, Wiviott SD, ''et al'' |title=Cytochrome P-450 Polymorphisms and Response to Clopidogrel |journal=N. Engl. J. Med. |volume8 KB (1,130 words) - 17:34, 10 February 2024
- 12 bytes (1 word) - 01:10, 31 January 2008
- 213 bytes (25 words) - 17:07, 14 May 2010
- 195 bytes (29 words) - 07:21, 30 September 2009
- Isoenzyme of cytochrome P-450.66 bytes (7 words) - 04:02, 16 December 2011
- Auto-populated based on [[Special:WhatLinksHere/Cytochrome P-450]]. Needs checking by a human.926 bytes (114 words) - 15:48, 11 January 2010
Page text matches
- #REDIRECT [[Cytochrome P-450]]30 bytes (3 words) - 00:31, 24 February 2009
- Isoenzyme of cytochrome P-450.66 bytes (7 words) - 04:02, 16 December 2011
- Citalopram is metabolised by [[cytochrome P-450]] CYP3A4 and [[Cytochrome P-450 CYP2C19|CYP2C19]]. ...ion]] has issued a warning to not use higher doses because of use of the [[cytochrome P-450]] system and also arrhythmias.<ref>{{cite web |url= http://www.fda.gov/Safe1 KB (123 words) - 11:44, 2 February 2023
- * [[Duloxetine]]. A moderate inhibitor of[[cytochrome P-450 CYP2D6]].<ref name="IndianaP450">[http://medicine.iupui.edu/clinpharm/ddis/ * [[Fluoxetine]] (generic). A strong inhibitor of [[cytochrome P-450 CYP2D6]].<ref name="IndianaP450">[http://medicine.iupui.edu/clinpharm/ddis/3 KB (345 words) - 09:46, 13 February 2011
- {{r|Cytochrome P-450}}349 bytes (43 words) - 08:14, 10 September 2008
- * [[Cytochrome P-450]]445 bytes (51 words) - 02:11, 7 October 2013
- In [[biology]], the '''cytochrome P-450 CYP2D6''' is a "[[cytochrome P-450]] enzyme that catalyzes the hydroxylation of many drugs and environmental c ...due to inhibiting metabolism of [[tamoxifen]] to its active metabolite by cytochrome P-450 CYP2D6.<ref>{{Cite journal | doi = 10.1136/bmj.c693 | volume = 340 | issue3 KB (483 words) - 17:34, 10 February 2024
- Tamoxifen is metabolized in the liver by [[cytochrome P-450 CYP2D6]] to active metabolites. ...en due to inhibiting metabolism of tamoxifen to its active metabolite by [[cytochrome P-450 CYP2D6]].<ref>{{Cite journal | doi = 10.1136/bmj.c693 | volume = 340 | issu2 KB (211 words) - 19:00, 2 July 2010
- {{r|Cytochrome P-450}}490 bytes (63 words) - 17:08, 11 January 2010
- {{r|Cytochrome P-450}}541 bytes (70 words) - 19:39, 11 January 2010
- {{r|Cytochrome P-450}}638 bytes (80 words) - 11:56, 11 January 2010
- {{r|Cytochrome P-450}}666 bytes (86 words) - 11:35, 11 January 2010
- {{r|Cytochrome P-450}}616 bytes (75 words) - 16:49, 11 January 2010
- ...] and [[myoglobin]]."<ref>{{MeSH}}</ref> [[Heme]] is also a component of [[cytochrome P-450]].715 bytes (98 words) - 08:18, 10 September 2008
- {{r|Cytochrome P-450}}798 bytes (96 words) - 10:58, 11 January 2010
- {{r|Cytochrome P-450}}751 bytes (96 words) - 11:59, 11 January 2010
- Paroxetine is metabolized in the liver by [[cytochrome P-450 CYP2D6]]. ...ue to inhibiting metabolism of [[tamoxifen]] to its active metabolite by [[cytochrome P-450 CYP2D6]].<ref>{{Cite journal | doi = 10.1136/bmj.c693 | volume = 340 | issu2 KB (279 words) - 11:00, 10 February 2010
- Auto-populated based on [[Special:WhatLinksHere/Cytochrome P-450]]. Needs checking by a human.926 bytes (114 words) - 15:48, 11 January 2010
- {{r|Cytochrome P-450}}898 bytes (111 words) - 19:11, 11 January 2010
- {{r|Cytochrome P-450}}850 bytes (136 words) - 17:21, 19 June 2008
- ...84">{{cite journal |author=Mega JL, Close SL, Wiviott SD, ''et al'' |title=Cytochrome P-450 Polymorphisms and Response to Clopidogrel |journal=N. Engl. J. Med. |volume ...Mega JL, Close SL, Wiviott SD, Shen L, Hockett RD, Brandt JT et al.| title=Cytochrome p-450 polymorphisms and response to clopidogrel. | journal=N Engl J Med | year= 27 KB (1,047 words) - 19:45, 16 October 2011
- ===Cytochrome P-450=== {{main|cytochrome P-450}}6 KB (767 words) - 17:34, 10 February 2024
- Escitalopram is metabolised by [[cytochrome P-450]] CYP3A4 and [[Cytochrome P-450 CYP2C19|CYP2C19]].4 KB (501 words) - 13:18, 2 February 2023
- ...ome P-450]] (microsomal) enzyme system. ... minimal effects of the drug on cytochrome P-450 enzymes have been suggested, and additional experience with long-term thera4 KB (517 words) - 13:22, 2 February 2023
- Propranolol is metabolized in the liver by several isoenzymes of [[cytochrome P-450]].2 KB (236 words) - 14:07, 2 February 2023
- Methadone is metabolized by [[cytochrome P-450]].2 KB (237 words) - 07:35, 18 October 2013
- ...statin]], [[simvastatin]], or [[gemfibrozil]] that are metabolized by [[cytochrome P-450]] may increase bleeding when added to patients taking [[warfarin]].<ref n2 KB (227 words) - 07:30, 11 May 2010
- ...interactions. Tables are available to check for drug interactions due to [[cytochrome P-450]] interactions.<ref>{{cite web |url=http://medicine.iupui.edu/flockhart/ |t ** http://drug-interactions.com - [[Cytochrome P-450]]9 KB (1,188 words) - 11:45, 2 February 2023
- ...nazole increases cell permeability by interacting with 14-α demethylase, a cytochrome P-450 enzyme necessary in the conversion of [[lanosterol]] to [[ergosterol]], a n2 KB (244 words) - 01:28, 3 June 2009
- ...other [[azole]]-based antifungal agents, it inhibits 14-alpha-methylase, a cytochrome P-450 enzyme that converts [[lanosterol]] to [[ergosterol]], an essential compone2 KB (240 words) - 03:51, 3 June 2009
- ...84">{{cite journal |author=Mega JL, Close SL, Wiviott SD, ''et al'' |title=Cytochrome P-450 Polymorphisms and Response to Clopidogrel |journal=N. Engl. J. Med. |volume8 KB (1,130 words) - 17:34, 10 February 2024
- It is not metabolized by [[cytochrome P-450]] [http://www.ncbi.nlm.nih.gov/sites/entrez/?db=gene&cmd=Retrieve&dopt=summ2 KB (313 words) - 14:09, 4 July 2009
- '''Cytochrome P-450''' is a "superfamily of hundreds of closely related hemeproteins found thro Cytochrome P-450's role in drug metabolism is described by Wolf:<ref name="pmid10723863">{{c22 KB (2,960 words) - 17:35, 10 February 2024
- ...gn prostatic hypertrophy]]. Both of these medications are metaoblized by [[cytochrome P-450 CYP3A4]].Dutasteride may better prevent acute urinary retention rates than3 KB (344 words) - 22:14, 22 August 2010
- ...agents, itraconazole interacts with 14-<math>\alpha</math>-demethylase, a cytochrome P-450 enzyme necessary to convert [[lanosterol]] to [[ergosterol]], an essential2 KB (308 words) - 08:21, 8 June 2009
- It is metabolized by [[cytochrome P-450]] [http://www.ncbi.nlm.nih.gov/sites/entrez/?db=gene&cmd=Retrieve&dopt=summ7 KB (1,032 words) - 13:16, 2 February 2023
- ...medications that induce [[cytochrome P-450]].<ref name="pmid18579817"/> [[Cytochrome P-450]] is a [[hemeprotein]] that consists of a [[heme]] group and [[heme]] is ir8 KB (1,068 words) - 08:23, 10 September 2008
- Colchicine is metabolized by the CYP3A4 [[isoenzyme]] of [[cytochrome P-450]] and may interact with other durgs with similar metabolism.<ref name="pmid5 KB (683 words) - 17:25, 30 April 2010
- Buprenorphine is metabolized by [[cytochrome P-450]], specifically the .<ref name="pmid15743975">{{cite journal| author=Picard6 KB (820 words) - 11:49, 2 February 2023
- ...ncluding [[antidepressant]]s. Coadministration of drugs that inhibit the [[cytochrome P-450]] CYP2D6 and CYP3A4 metabolism of [[antidepressant]]s may increase the risk4 KB (592 words) - 19:49, 16 August 2016
- Proton pump inhibitors are metabolized by the CYP2C19 isoenzyme of [[cytochrome P-450]]. Lanzoprazole is the strongest inhibitor of CYP2C19,<ref name="pmid152581 ...are metabolized by the [[Cytochrome P-450 CYP2C19|CYP2C19]] isoenzyme of [[cytochrome P-450]], may or may not increase adverse cardiac events when given to patients ta26 KB (3,487 words) - 14:06, 2 February 2023
- [[Mass screening|Screening]] for [[Cytochrome P-450]] 2C9 polymorphisms may improve [[warfarin]] dosing cmopared to the Ageno a5 KB (713 words) - 17:34, 10 February 2024
- ** Hepatically metabolized by [[cytochrome P-450]] [http://www.ncbi.nlm.nih.gov/sites/entrez/?db=gene&cmd=Retrieve&dopt=summ ===Cytochrome P-450===35 KB (4,629 words) - 08:41, 6 May 2024
- ...holesterolemia]] and elevated [[liver]] [[Cytochrome_P-450#Drug_Metabolism|cytochrome p-450 measurements]]. Reproductive studies in rats resulted in no observable effe10 KB (1,538 words) - 15:31, 8 March 2023
- ...y contribute<ref name="pmid18541823"/>, in some cases due to an abnormal [[cytochrome P-450]] 3A5 allele that may reduce metabolism of [[cortisol]] and [[corticosteron9 KB (1,159 words) - 14:09, 2 February 2023
- ...en statins are given with patients who are also taking inhibitors of the [[cytochrome P-450]] isoenzyme 3A4.<ref name="pmid23778904">{{cite journal| author=Patel AM, S14 KB (1,963 words) - 10:30, 28 August 2013
- ...The most important role is in the [[heme]] protein of [[hemoglobin]] and [[cytochrome P-450]], and secondarily for [[myoglobin]], which transports oxygen into muscle c8 KB (1,113 words) - 19:55, 28 September 2010
- ...ion]] has issued a warning to not use higher doses because of use of the [[cytochrome P-450]] system and also arrhythmias.<ref>{{cite web |url= http://www.fda.gov/Safe11 KB (1,448 words) - 14:12, 2 February 2023
- **Non-thienopyridine [[ticagrelor]] does not undergo metabolism by [[cytochrome P-450]] and is a reversible binder12 KB (1,658 words) - 08:52, 28 June 2011
- ...rular filtration rate]]. Atenolol is ''not'' metabolized in the liver by [[cytochrome P-450]] [http://www.ncbi.nlm.nih.gov/sites/entrez/?db=gene&cmd=Retrieve&dopt=sum16 KB (2,243 words) - 11:52, 2 February 2023
- Some interactions are due to the system of [[cytochrome P-450]] enzymes used to clear drugs from the body. These interactions can be comp ...g metabolism. Tables are available to check for drug interactions due to [[cytochrome P-450]] interactions.<ref>{{cite web |url=http://medicine.iupui.edu/flockhart/ |t39 KB (5,361 words) - 17:35, 10 February 2024
- Some opioids are metabolized by [[cytochrome P-450]] and [[cytochrome P-450 CYP2D6]].<ref name="pmid19059064">{{cite journal| author=Reynolds KK, Ramey ...ast to [[hydrocodone]], [[oxycodone]] and [[codeine]] and metabolized by [[cytochrome P-450 CYP2D6]] which may lead to variable [[pharmacokinetics]] due to [[single-nu42 KB (5,794 words) - 14:08, 2 February 2023
- ''CYP2C9'' is an [[isoenzyme]] of [[cytochrome P-450]]. [[Genetic polymorphism|Polymorphisms]] of CYP2C9 explain another 10% of * Interference with warfarin metabolism by [[cytochrome P-450]] CYP2C9 [[isoenzyme]].52 KB (7,136 words) - 22:53, 6 April 2014
- ...l |issn=}}</ref> that are not metabolized by the CYP3A4 [[isoenzyme]] of [[cytochrome P-450]] ([[naproxen]] is not metabolized by CYP3A4). Combining [[glucocorticoid]]24 KB (3,312 words) - 17:35, 10 February 2024
- ...y contribute<ref name="pmid18541823"/>, in some cases due to an abnormal [[cytochrome P-450]] 3A5 allele that may reduce metabolism of [[cortisol]] and [[corticosteron56 KB (7,418 words) - 15:13, 5 November 2013
- * [[Cytochrome P-450]]25 KB (3,396 words) - 13:29, 2 April 2024