From Citizendium
Jump to navigation Jump to search
This article is a stub and thus not approved.
Main Article
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
This editable Main Article is under development and subject to a disclaimer.
IUPAC name:

 Uses: hypertention;angina pectoris

 Properties: lipophilic

 Hazards: see side effects & drug interactions

Mass (g/mol): CAS #:

In medicine, propranolol is "a widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for myocardial infarction; arrhythmia; angina pectoris; hypertension; hyperthyroidism; migraine; pheochromocytoma; and anxiety but adverse effects instigate replacement by newer drugs."[1]


Propranolol was developed by James Black who later received the Nobel Prize for this and other work.[2]

Propranolol was marketed in the United States of America by Akrimax Pharms. Propranolol received approval in the United States of America November 13, 1967.[3]

Generic propranolol was available October 22, 1985.[4]


Propranolol is metabolized in the liver by several isoenzymes of cytochrome P-450.

External links

The most up-to-date information about Propranolol and other drugs can be found at the following sites.


  1. Anonymous (2023), Propranolol (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Stapleton MP (1997). "Sir James Black and propranolol. The role of the basic sciences in the history of cardiovascular pharmacology". Tex Heart Inst J 24 (4): 336–42. PMID 9456487. PMC 325477[e]
  3. Drugs@FDA. U S Food and Drug Administration
  4. Drugs@FDA. U S Food and Drug Administration