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! [[Allele]] !! [[Nucleotide]] change * CYP2C9*2 allele:

...pelto M, Helkala EL, Laakso MP, ''et al'' |title=Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood

....gov/sites/entrez/?db=gene&cmd=Retrieve&dopt=summary&list_uids=1565 2D6] [[allele]] and so may have drug interactions<ref name="pmid18452693">{{cite journal

...ffects of Three Simulated Systems of Inbreeding on the Frequency of the tw Allele in Wild Populations of Mus Musculus on nomination of Richard C. Lewontin"

...measure of the degree of genetic diversity in a population, and changes in allele frequencies in the gene pool give objective evidence that evolution has occ ...trait is heritable, selection can alter the frequencies of the different [[allele]]s (variants of a gene) that are responsible for that variability. Selectio

...mal metabolism by [[cytochrome P-450]] due to either inheriting abnormal [[allele]]s or due to drug interactions. Tables are available to check for drug inte

...creasing body weight by around 1.3 to 2.1 kilograms, the frequency of risk allele expression is high in the European population at around 63% [22]. This is t ...n. A polygene can only be identified and validated by showing that such an allele occurs more frequently in obese patients than those that are not obese. Eve

...successive generations, as determined by shifts in the [[allele frequency|allele frequencies]] of [[gene]]s. Over time, this process can result in [[speciat ...ral or beneficial, are pushed towards fixation along with the beneficial [[allele]].

...pmid18541823"/>, in some cases due to an abnormal [[cytochrome P-450]] 3A5 allele that may reduce metabolism of [[cortisol]] and [[corticosterone]] (a precur

...tted the ancestors of the Maine Coon, there is no doubt that a recessive [[allele]] for long hair in the gene pool of European domestic cats at the time, and

...e D2 receptors, which may be predisposed by genetic polymorphisms of the [[allele]], may cause [[neuroleptic malignant syndrome]].<ref name="pmid15094790">{{

...creased levels of total 25-hydroxyvitamin D among blacks. In whites, the A allele at rs4588 was associated with decreased levels of total 25-hydroxyvitamin D

* If only ''one'' β globin allele bears a mutation, '''β thalassemia minor''' results (sometimes referred to .../entrez/dispomim.cgi?cmd=entry&id=187550 |title=THALASSEMIA, BETA+, SILENT ALLELE|author= |authorlink= |coauthors= |date= |format= |work= |publisher=Online M

...ich have no evidence of this mutation. Similarly, the '''apolipoprotein E4 allele''' which is a risk factor in Alzheimer’s shows no association with FTLD.

....gov/sites/entrez/?db=gene&cmd=Retrieve&dopt=summary&list_uids=1565 2D6] [[allele]] ...ch as [[metoprolol]] that are metabolized by [[cytochrome P-450 CYP2D6]] [[allele]] and may have more [[drug interaction]]s<ref name="pmid18452693">{{cite jo

....gov/sites/entrez/?db=gene&cmd=Retrieve&dopt=summary&list_uids=1565 2D6] [[allele]].

...pelto M, Helkala EL, Laakso MP, ''et al'' |title=Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood

...the transposon provides a straightforward means of identifying the mutant allele, relative to chemical mutagenesis methods.

...f> Several genes have been identified as ‘obesity genes’ and although each allele would cause very little variance in BMI alone, a polygenic explanation seem

...ignificant when restricted to analysis of patients with a reduced function allele

...yme disease vaccine nor inflammatory arthritis (normal controls). HLA-DRB1 allele typing, Western blotting for Lyme antigen, and T cell reactivity testing we

* CYP2C9*2 allele: * CYP2C9*3 allele:

...Rhoades, M. M. (1938). Effect of the Dt gene on the mutability of the a1 allele in maize. Genetics 23, 377-397. Rhoades, M. M. (1941). The genetic control

...s > European Americans > African Americans. They also found that another [[allele]] encoding S453I mutation was associated with lower hepatic fat content in

...pea might be wrinkled or smooth, for example, and the particular pair of [[allele]]s inherited by each pea then determined what the next generation would be

...coding conserved metabolic functions, are [[polymorphic]], with multiple [[allele]]s found among different isolates <ref>Whittam, T.S. 1996. Genetic variatio

...ur claws on each of their hind paws and five on their front paws, but an [[allele]] in the gene pool makes them prone to [[polydactyly]], and some have six o

Inheriting abnormal [[allele]]s of [[cytochrome P-450]] can alter drug metabolism. Tables are available

...pea might be wrinkled or smooth, for example, and the particular pair of [[allele]]s inherited by each pea then determined what the next generation would be

...pea might be wrinkled or smooth, for example, and the particular pair of [[allele]]s inherited by each pea then determined what the next generation would be

...pmid18541823"/>, in some cases due to an abnormal [[cytochrome P-450]] 3A5 allele that may reduce metabolism of [[cortisol]] and [[corticosterone]] (a precur