Methotrexate/Definition: Difference between revisions

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An inhibitor of [[tetrahydrofolate dehydrogenase]], which prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA. Wide range of applications, including the treatment of cancer; autoimmune diseases (where it is considered a [[disease-modifying antirheumatic drug]]) including [[asthma]], [[rheumatoid arthritis]].
An inhibitor of [[tetrahydrofolate dehydrogenase]], which prevents the formation of [[tetrahydrofolate]], necessary for synthesis of [[thymidylate]], an essential component of [[DNA]]; it has a wide range of medical applications.

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A definition or brief description of Methotrexate.

An inhibitor of tetrahydrofolate dehydrogenase, which prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA; it has a wide range of medical applications.