Talk:Methotrexate

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 Definition:  An inhibitor of tetrahydrofolate dehydrogenase, which prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA; it has a wide range of medical applications. [d] [e]
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 Workgroup category:  Health Sciences [Editors asked to check categories]
 Subgroup categories:  Oncology, Rheumatology and Pulmonary medicine
 Talk Archive:  none  English language variant:  American English
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