Acebutolol: Difference between revisions
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imported>David E. Volk (New page: {{subpages}} {{Chem infobox |align=right |image=center|thumb|300px |width=300px |molname=acebutolol |synonyms= dl-acebutolol |molformula= C<sub>18</sub>H<sub>28</...) |
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Revision as of 14:52, 4 July 2009
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acebutolol | |||||||
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Uses: | hypertention;angina pectoris | ||||||
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Acebutolol is a cardioselective, beta-adrenergic antagonist (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as atenolol and propranolol. Epinephrine typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interferring with epinephrine binding. Blood pressure is also increased by the release of renin, a hormone produced in the kidneys, which narrows blood vessels. By preventing renin release, acebutolol reduces blood pressure by a second mechanism.Acebutolol at DrugBank