Acebutolol: Difference between revisions

From Citizendium
Jump to navigation Jump to search
imported>David E. Volk
(New page: {{subpages}} {{Chem infobox |align=right |image=center|thumb|300px |width=300px |molname=acebutolol |synonyms= dl-acebutolol |molformula= C<sub>18</sub>H<sub>28</...)
 
imported>David E. Volk
No edit summary
Line 15: Line 15:
}}
}}


'''Acebutolol''' is a cardioselective, [[beta-adrenergic antagonist]] (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as [[atenolol]] and [[propranolol]]. [[Epinephrine]] typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interferring with epinephrine binding.  Blood pressure is also increased by the release of [[renin]], a [[hormone]] produced in the kidneys, which narrows blood vessels.  By preventing renin release, acebutolol reduces blood pressure by a second mechanism.[http://www.drugbank.ca/drugs/DB01193 Acebutolol at DrugBank]
'''Acebutolol''' is a cardioselective, [[beta-adrenergic antagonist]] (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as [[atenolol]] and [[propranolol]]. [[Epinephrine]] typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interferring with epinephrine binding.  Blood pressure is also increased by the release of [[renin]], a [[hormone]] produced in the kidneys, which narrows blood vessels.  By preventing renin release, acebutolol reduces blood pressure by a second mechanism. <ref>[http://www.drugbank.ca/drugs/DB01193 Acebutolol at DrugBank]</ref>


== References ==
== References ==
<references/>
<references/>

Revision as of 14:53, 4 July 2009

This article is developing and not approved.
Main Article
Discussion
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
 
This editable Main Article is under development and subject to a disclaimer.
Acebutolol.png
acebutolol
IUPAC name: see chemistry section
Synonyms: dl-acebutolol
Formula: C18H28N2O4

 Uses: hypertention;angina pectoris

 Properties:

 Hazards:

Mass (g/mol): CAS #:
336.4259 37517-30-9


Acebutolol is a cardioselective, beta-adrenergic antagonist (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as atenolol and propranolol. Epinephrine typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interferring with epinephrine binding. Blood pressure is also increased by the release of renin, a hormone produced in the kidneys, which narrows blood vessels. By preventing renin release, acebutolol reduces blood pressure by a second mechanism. [1]

References