Sarcoidosis

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In medicine, sarcoidosis is an "idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.[1]

Complications

Cardiac sarcoidosis

Neurosarcoidosis

Neuropathy

Sarcoidosis can cause various patterns of neuropathy.[2][3][4][5] Causes of neuropathy include vasculitis and compression from granulomas.

References

  1. Anonymous (2024), Sarcoidosis (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Vital A, Lagueny A, Ferrer X, Louiset P, Canron MH, Vital C (2008). "Sarcoid neuropathy: clinico-pathological study of 4 new cases and review of the literature". Clin. Neuropathol. 27 (2): 96–105. PMID 18402389[e]
  3. Garg S, Wright A, Reichwein R, Boyer P, Towfighi J, Kothari MJ (February 2005). "Mononeuritis multiplex secondary to sarcoidosis". Clin Neurol Neurosurg 107 (2): 140–3. DOI:10.1016/j.clineuro.2004.06.009. PMID 15708231. Research Blogging.
  4. Burns TM, Dyck PJ, Aksamit AJ, Dyck PJ (May 2006). "The natural history and long-term outcome of 57 limb sarcoidosis neuropathy cases". J. Neurol. Sci. 244 (1-2): 77–87. DOI:10.1016/j.jns.2006.01.014. PMID 16524595. Research Blogging.
  5. Dreyer M, Vucic S, Cros DP, Chong PS (November 2004). "Multiple painful sensory mononeuropathies (MPSM), a novel pattern of sarcoid neuropathy". J. Neurol. Neurosurg. Psychiatr. 75 (11): 1645–6. DOI:10.1136/jnnp.2003.028134. PMID 15489408. PMC 1738798. Research Blogging.