Cefacetrile

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cefacetrile
IUPAC name: see chemistry section Synonyms: Formula: C13H13N3O6S
Uses:	antibiotic drug
Properties:	beta-lactam
Hazards:	see drug interactions
Mass (g/mol): CAS #: 339.3240 10206-21-0

Cefacetrile is a first-generation cephalosporin antibiotic medication used to treate bacterial infections. It is sold under the brand names Celospor®, Celtol® and Cristacef®. It a 7-cyanacetylamino derivative of cephalosporic acid, and is also called by the synonyms cefacetrilo, cefacetrilum and cephacetrile.

Chemistry

The IUPAC name of cefacetrile is (6R,7R)-3-(acetyloxymethyl)-7-[(2-cyanoacetyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, and its chemical formula, C₁₃H₁₃N₃O₆S, yields an average molecular mass of 339.3240 gram/mole. Its antibacterial activity is due to the presence of a beta-lactam core structure, which bind with penicillin-binding proteins within bacterial cells, thereby inhibiting cell wall synthesis in bacteria.

References

The most up-to-date information about Cefacetrile and other drugs can be found at the following sites.

• Cefacetrile - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Cefacetrile - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
• Cefacetrile - Detailed information from DrugBank.