Fludrocortisone: Difference between revisions
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Fludrocortisone one mg orally per day is equivalent to [[aldosterone]] 4 mg intramuscularly every six hours.<ref name="pmid13249284">{{cite journal |author=Thorn GW, Sheppard RH, Morse WI, Reddy WJ, Beigelman PM, Renold AE |title=Comparative action of aldosterone and 9-alpha-fluorohydrocortisone in man |journal=Ann. N. Y. Acad. Sci. |volume=61 |issue=2 |pages=609–19 |year=1955 |month=May |pmid=13249284 |doi= |url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0077-8923&date=1955&volume=61&spage=609 |issn=}}</ref> | Fludrocortisone one mg orally per day is equivalent to [[aldosterone]] 4 mg intramuscularly every six hours.<ref name="pmid13249284">{{cite journal |author=Thorn GW, Sheppard RH, Morse WI, Reddy WJ, Beigelman PM, Renold AE |title=Comparative action of aldosterone and 9-alpha-fluorohydrocortisone in man |journal=Ann. N. Y. Acad. Sci. |volume=61 |issue=2 |pages=609–19 |year=1955 |month=May |pmid=13249284 |doi= |url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0077-8923&date=1955&volume=61&spage=609 |issn=}}</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 09:29, 29 October 2024
Fludrocortisone has at least 50[1][2] times more mineralocorticoid activity than hydrocortisone.
Fludrocortisone one mg orally per day is equivalent to aldosterone 4 mg intramuscularly every six hours.[3]
Attribution
- Some content on this page may previously have appeared on Wikipedia.
References
- ↑ Goldfien A, Laidlaw JC, Haydar NA, Renold AE, Thorn GW (March 1955). "Fluorohydrocortisone and chlorohydrocortisone, highly potent derivatives of compound F". N. Engl. J. Med. 252 (11): 415–21. PMID 14356353. [e]
- ↑ Thorn GW, Renold AE, Morse WI, Goldfien A, Reddy WJ (November 1955). "Highly potent adrenal cortical steroids: structure and biologic activity". Ann. Intern. Med. 43 (5): 979–1000. PMID 13268992. [e]
- ↑ Thorn GW, Sheppard RH, Morse WI, Reddy WJ, Beigelman PM, Renold AE (May 1955). "Comparative action of aldosterone and 9-alpha-fluorohydrocortisone in man". Ann. N. Y. Acad. Sci. 61 (2): 609–19. PMID 13249284. [e]