Antihypertensive: Difference between revisions

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'''Antihypertensives''' are ''drugs'' or [[pharmacology|pharmacological]] ''agents'' that are used to treat [[hypertension]].
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An '''antihypertensive''' is one of a class of [[medication]]s that is used to treat [[hypertension]] (high blood pressure).  Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as [[stroke]], heart failure, kidney failure and [[myocardial infarction]]. Evidence suggests that reduction of the [[blood pressure]] by 5&nbsp;mmHg can decrease the risk of stroke by 34% and of ischaemic heart disease by 21%, and can reduce the likelihood of [[dementia]], [[heart failure]], and [[death|mortality]] from cardiovascular disease.<ref>{{cite journal | vauthors = Law M, Wald N, Morris J | title = Lowering blood pressure to prevent myocardial infarction and stroke: a new preventive strategy | journal = Health Technology Assessment | volume = 7 | issue = 31 | pages = 1–94 | year = 2003 | pmid = 14604498 | doi = 10.3310/hta7310 | doi-access = free }}</ref> There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used medications are thiazide diuretics, calcium channel blockers, [[ACE inhibitor]]s, [[angiotensin II receptor antagonist]]s (ARBs), and [[beta blocker]]s.
 
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Latest revision as of 12:07, 27 July 2024

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An antihypertensive is one of a class of medications that is used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34% and of ischaemic heart disease by 21%, and can reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease.[1] There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used medications are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.

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Notes

  1. (2003) "Lowering blood pressure to prevent myocardial infarction and stroke: a new preventive strategy". Health Technology Assessment 7 (31): 1–94. DOI:10.3310/hta7310. PMID 14604498. Research Blogging.