British Doctors Aspirin Trial

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The British Doctors Aspirin Trial was a randomized controlled trial started about 1980 that was designed to test chemoprevention with aspirin for the primary prevention of vascular disease.[1]

Secondary analysis of the British Doctors Aspirin Trial suggest aspirin may reduce colorectal cancer.[2]


  1. Peto R, Gray R, Collins R, Wheatley K, Hennekens C, Jamrozik K et al. (1988). "Randomised trial of prophylactic daily aspirin in British male doctors.". Br Med J (Clin Res Ed) 296 (6618): 313-6. PMID 3125882. PMC PMC2544821.
  2. Flossmann E, Rothwell PM, British Doctors Aspirin Trial and the UK-TIA Aspirin Trial (2007). "Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies.". Lancet 369 (9573): 1603-13. DOI:10.1016/S0140-6736(07)60747-8. PMID 17499602. Research Blogging. Review in: ACP J Club. 2007 Nov-Dec;147(3):72