Tenofovir: Difference between revisions

From Citizendium
Jump to navigation Jump to search
imported>David E. Volk
 
imported>David E. Volk
mNo edit summary
Line 1: Line 1:
{{subpages}}
{{subpages}}
[[Image:Tenofovir structure.jpg|right|thumb|200px|{{#ifexist:Template:Tenofovir structure.jpg/credit|{{Tenofovir structure.jpg/credit}}<br/>|}}Tenofovir]]  
[[Image:Tenofovir structure.jpg|right|thumb|200px|{{#ifexist:Template:Tenofovir structure.jpg/credit|{{Tenofovir structure.jpg/credit}}<br/>|}}Tenofovir]]  
'''Tenofovir''' is a nucleotide analog [[reverse transcritase inhitor]] (nRTI) [[antiviral drug]] used to treat [[HIV]]/[[AIDS]] and is in clinical trials for treatment of [[hepatitis B]] infection.  The triphosphate from of the drug competes with the natural [[DNA]] [[nucleotide]] [[deoxyadenosine triphosphate]] (dATP) during DNA formation and it acts as a DNA chain terminator once incorporated because it lacks the normal [[deoxyribose]] sugar needed for connecting to the next DNA base.  
'''Tenofovir''' is a nucleotide analog [[reverse transcritase inhibitor]] (nRTI) [[antiviral drug]] used to treat [[HIV]]/[[AIDS]] and is in clinical trials for treatment of [[hepatitis B]] infection.  The triphosphate from of the drug competes with the natural [[DNA]] [[nucleotide]] [[deoxyadenosine triphosphate]] (dATP) during DNA formation and it acts as a DNA chain terminator once incorporated because it lacks the normal [[deoxyribose]] sugar needed for connecting to the next DNA base.  


== Synonyms and brand names ==
== Synonyms and brand names ==

Revision as of 14:01, 3 February 2008

This article is a stub and thus not approved.
 Main Article
 Discussion
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
 
https://en.citizendium.org/wiki/index.php?title=Tenofovir&printable=yes
This editable Main Article is under development and subject to a disclaimer.
(CC) Image: David E. Volk
Tenofovir

Tenofovir is a nucleotide analog reverse transcritase inhibitor (nRTI) antiviral drug used to treat HIV/AIDS and is in clinical trials for treatment of hepatitis B infection. The triphosphate from of the drug competes with the natural DNA nucleotide deoxyadenosine triphosphate (dATP) during DNA formation and it acts as a DNA chain terminator once incorporated because it lacks the normal deoxyribose sugar needed for connecting to the next DNA base.

Synonyms and brand names

Synonyms

  • Tenofovir disoproxil
  • Tenofovir disoproxil fumarate
  • D,L-Tenofovir
  • TDF
  • PMPA

Brand Names

  • Apropovir
  • Viread

External links

Retrieved from "https://citizendium.org/wiki/index.php?title=Tenofovir&oldid=401256"