Talk:Adrenergic beta-antagonist

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Revision as of 16:56, 3 January 2009 by imported>Howard C. Berkowitz (→‎Second paragraph of the introduction -- more needed?: new section)
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 Definition:  Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. [d] [e]
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 Workgroup category:  Health Sciences [Editors asked to check categories]
 Subgroup category:  Cardiology
 Talk Archive:  none  English language variant:  American English

Second paragraph of the introduction -- more needed?

The second sentence of the second paragraph of the introduction reads

Beta-blockers that have low intrinsic sympathomimetic activity (ISA), low membrane stabilizing activity, high beta 1-selectivity, and high lipophilicity may be more effective

Effective for all indications, or, as the citation seems to suggest, for increased survival in at least some types of cardiovascular disease, or just the labeled indications (for metoprolol at least): Acute Coronary Syndrome, Chronic Angina Pectoris, Hypertension, Myocardial Infarction, Myocardial Reinfarction Prevention.

Are these characteristics true for all indications, such as migraine prophylaxis, benign intentional tremor, heart failure, hypertrophic cardiopathy, mitral valve prolapse, thyrotoxicosis, etc.?Howard C. Berkowitz 21:56, 3 January 2009 (UTC)

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