Second-generation antidepressant: Difference between revisions

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'''Second-generation antidepressants''' are a "structurally and mechanistically diverse group of drugs that are not [[tricyclic antidepressant|tricyclics]] or [[monoamine oxidase inhibitor]]s. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake."<ref>{{MeSH|Second-generation antidepressants}}</ref>
'''Second-generation [[antidepressant]]s''' are used to treat [[depression]] and are a "structurally and mechanistically diverse group of drugs that are not [[tricyclic antidepressant|tricyclics]] or [[monoamine oxidase inhibitor]]s. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake."<ref>{{MeSH|Second-generation antidepressants}}</ref>


==Classification==
==Classification==
Second-generation antidepressant are classified by the [[biogenic amine receptor]] that they affect.
Second-generation antidepressants are classified by the [[biogenic amine receptor]] that they affect.
===Selective serotonin reuptake inhibitors(SSRI)===
===Selective serotonin reuptake inhibitors(SSRI)===
* [[Fluoxetine]]
* [[Fluoxetine]]

Revision as of 14:33, 25 February 2008

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Second-generation antidepressants are used to treat depression and are a "structurally and mechanistically diverse group of drugs that are not tricyclics or monoamine oxidase inhibitors. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake."[1]

Classification

Second-generation antidepressants are classified by the biogenic amine receptor that they affect.

Selective serotonin reuptake inhibitors(SSRI)

Serotonin 5-HT2–receptor agonist

Serotonin norepinephrine reuptake inhibitors (SNRI)

Norepinephrine uptake inhibitor

Dopamine reuptake inhibitor

References