P:F ratio: Difference between revisions

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In [[pulmonary medicine]], [[critical care]] and [[anesthesiology]], the '''P:F ratio''' is the ratio of arterial oxygen concentration to the fraction of inspired oxygen. It reflects how well the lungs absorb oxygen from expired air. <ref>{{citation
| journal = Medscape Medical News
| contribution = P/F Ratio May Be a Marker of Potential Intraoperative Ventilator-Induced Lung Injury
| title = Coverage of the American Society of Anesthesiologists (ASA) 2009 Annual Meeting
| author = Caroline Helwick
| url = http://www.medscape.com/viewarticle/711235}}</ref>
:<math>{P/F\  ratio} = \left (\frac{PaO_2}{Fi0_2}\right) \times 100</math>
:<math>{P/F\  ratio} = \left (\frac{PaO_2}{Fi0_2}\right) \times 100</math>
An  example in a healthy person:
An  example in a healthy person:
Line 5: Line 13:
A  higher ratio indicates better gas exchange:
A  higher ratio indicates better gas exchange:
* Normal is 500
* Normal is 500
* [[Adult respiratory distress syndrome|ARDS]] is <  200
* [[Acute respiratory distress syndrome|ARDS]] is <  200


Comparative studies suggest this measure  correlates better with pulmonary shunts than does the A-a gradient.<ref  name="pmid6409506">{{cite journal |author=Covelli HD, Nessan VJ, Tuttle WK |title=Oxygen  derived variables in acute respiratory failure |journal=Crit.  Care Med. |volume=11 |issue=8 |pages=646–9 |year=1983 |pmid=6409506 |doi=}}</ref><ref name="pmid14769743">{{cite journal |author=El-Khatib  MF, Jamaleddine GW |title=A new oxygenation index for reflecting  intrapulmonary shunting in patients undergoing open-heart surgery  |journal=Chest  |volume=125  |issue=2  |pages=592–6  |year=2004  |pmid=14769743  |doi=}}</ref><ref name="pmid3191742">{{cite journal |author=Cane  RD, Shapiro BA, Templin R, Walther K |title=Unreliability of oxygen tension-based  indices in reflecting intrapulmonary shunting in critically ill patients  |journal=Crit.  Care Med. |volume=16 |issue=12 |pages=1243–5 |year=1988 |pmid=3191742 |doi=}}</ref>
Comparative studies suggest this measure  correlates better with pulmonary shunts than does the A-a gradient.<ref  name="pmid6409506">{{cite journal |author=Covelli HD, Nessan VJ, Tuttle WK |title=Oxygen  derived variables in acute respiratory failure |journal=Crit.  Care Med. |volume=11 |issue=8 |pages=646–9 |year=1983 |pmid=6409506 |doi=}}</ref><ref name="pmid14769743">{{cite journal |author=El-Khatib  MF, Jamaleddine GW |title=A new oxygenation index for reflecting  intrapulmonary shunting in patients undergoing open-heart surgery  |journal=Chest  |volume=125  |issue=2  |pages=592–6  |year=2004  |pmid=14769743  |doi=}}</ref><ref name="pmid3191742">{{cite journal |author=Cane  RD, Shapiro BA, Templin R, Walther K |title=Unreliability of oxygen tension-based  indices in reflecting intrapulmonary shunting in critically ill patients  |journal=Crit.  Care Med. |volume=16 |issue=12 |pages=1243–5 |year=1988 |pmid=3191742 |doi=}}</ref>


==References==
==References==
<references/>
{{reflist|2}}

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In pulmonary medicine, critical care and anesthesiology, the P:F ratio is the ratio of arterial oxygen concentration to the fraction of inspired oxygen. It reflects how well the lungs absorb oxygen from expired air. [1]

An example in a healthy person:

A higher ratio indicates better gas exchange:

  • Normal is 500
  • ARDS is < 200

Comparative studies suggest this measure correlates better with pulmonary shunts than does the A-a gradient.[2][3][4]

References

  1. ↑ Caroline Helwick, P/F Ratio May Be a Marker of Potential Intraoperative Ventilator-Induced Lung Injury, "Coverage of the American Society of Anesthesiologists (ASA) 2009 Annual Meeting", Medscape Medical News
  2. ↑ Covelli HD, Nessan VJ, Tuttle WK (1983). "Oxygen derived variables in acute respiratory failure". Crit. Care Med. 11 (8): 646–9. PMID 6409506. [e]
  3. ↑ El-Khatib MF, Jamaleddine GW (2004). "A new oxygenation index for reflecting intrapulmonary shunting in patients undergoing open-heart surgery". Chest 125 (2): 592–6. PMID 14769743. [e]
  4. ↑ Cane RD, Shapiro BA, Templin R, Walther K (1988). "Unreliability of oxygen tension-based indices in reflecting intrapulmonary shunting in critically ill patients". Crit. Care Med. 16 (12): 1243–5. PMID 3191742. [e]
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