Net efficacy adjusted for risk

In statistics, net efficacy adjusted for risk (NEAR) is a measure that combines measure of efficacy and risk into a single metric. For example, the relative risk of efficacy can be combined with the relative risk for drug toxicity into a single NEAR RR. Alternatively, the odds ratio of efficacy can be combined with the odds ratio for drug toxicity into a single NEAR OR.

${\mbox{Net efficacy adjusted for risk (NEAR RR)}}={\mbox{Relative risk for efficacy }}\times {\mbox{ Relative risk for harm}}$

${\mbox{Net efficacy adjusted for risk (NEAR OR)}}={\mbox{Odds ratio for efficacy }}\times {\mbox{ Odds ratio for harm}}$

2×2 table combining efficacy and safety results of a theoretical controlled randomized clinical trial.