Histamine H2 antagonist: Difference between revisions
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In [[medicine]], '''histamine H2 antagonists''' are "drugs that selectively bind to but do not activate [[histamine H2 receptor]]s, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. [[Smooth muscle]] may also be affected. Some drugs in this class have strong effects in the [[central nervous system]], but these actions are not well understood."<ref>{{MeSH}}</ref> | In [[medicine]], '''histamine H2 antagonists''' are "drugs that selectively bind to but do not activate [[histamine H2 receptor]]s, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of [[gastrointestinal ulcers]]. [[Smooth muscle]] may also be affected. Some drugs in this class have strong effects in the [[central nervous system]], but these actions are not well understood."<ref>{{MeSH}}</ref> | ||
Clinically, therapy with H2 antagonists is usually complemented by [[proton pump inhibitor]]s. They may also be synergistic with [[histamine H1 antagonist]]s. | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 13:35, 9 June 2010
In medicine, histamine H2 antagonists are "drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood."[1]
Clinically, therapy with H2 antagonists is usually complemented by proton pump inhibitors. They may also be synergistic with histamine H1 antagonists.
References
- ↑ Anonymous (2024), Histamine H2 antagonist (English). Medical Subject Headings. U.S. National Library of Medicine.