Gyrification
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In brain anatomy, gyrification (also known as foliation) refers to the folding of the cerebral cortex during brain development in many vertebrate taxa, including songbirds, cetaceans and primates[1][2]. Although the underlying biomechanical mechanisms are not yet well understood, the overall folding pattern can be reasonably explained in terms of the cerebral cortex resembling a gel that buckles under the influence of non-isotropic forces[3]. Possible causes of the non-isotropy include thermal noise, variations in the number and timing of cell divisions, cell migration, cortical connectivity, pruning, brain size and metabolism (phospholipids in particular), all of which may interact[4][5].
See also
References
- ↑ Hofman, M.A. (1989). "On the evolution and geometry of the brain in mammals.". Prog Neurobiol 32 (2): 137-58. Retrieved on 2008-04-22.
- ↑ Armstrong, E.; Schleicher, A.; Omran, H.; Curtis, M.; Zilles, K. (1995). "The Ontogeny of Human Gyrification". Cerebral Cortex 5 (1): 56-63. Retrieved on 2008-04-22.
- ↑ Mora, T.; Boudaoud, A. (2006). "Buckling of swelling gels". The European Physical Journal E - Soft Matter 20 (2): 119-124. Retrieved on 2008-04-22.
- ↑ Price, D.J. (2004). "Lipids make smooth brains gyrate". Trends in Neurosciences 27 (7): 362-364. Retrieved on 2008-04-22.
- ↑ Toro, R.; Perron, M.; Pike, B.; Richer, L.; Veillette, S.; Pausova, Z.; Paus, T. (2008). "Brain Size and Folding of the Human Cerebral Cortex". Cerebral Cortex. Retrieved on 2008-04-22.