Cold probe (NMR)

In NMR spectroscopy a cold probe, also referred to as a Cryoprobe® (Bruker, Inc.) or a Chiliprobe (Varian, Inc.), is a radio frequency (typically 600-900 MHz) exitation and receiving probe in which the electronics are cooled to about 25 degrees above absolute zero. By doing this the electronic noise normally associated with electronic circuits is greatly reduced, resulting in a large signal-to-noise ratio (S/N) improvement. This allows data collection in about 1/10th of the time normally required using a room temperature probe for a similar S/N ratio.