Colchicine: Difference between revisions
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==Dosage== | ==Dosage== | ||
===Acute gout attack=== | |||
Initially 1 to 1.2 milligrams, then one of the following until symptoms better or gastrointestinal [[drug toxicity]] (stomach pain, vomiting or diarrhea) occur:<ref>Colchicine. In: DRUGDEX® System (Internet database). Greenwood Village, Colo: Thomson Healthcare. Updated periodically.</ref> | Initially 1 to 1.2 milligrams, then one of the following until symptoms better or gastrointestinal [[drug toxicity]] (stomach pain, vomiting or diarrhea) occur:<ref>Colchicine. In: DRUGDEX® System (Internet database). Greenwood Village, Colo: Thomson Healthcare. Updated periodically.</ref> | ||
* 0.5 to 0.6 milligram every hour | * 0.5 to 0.6 milligram every hour | ||
Revision as of 16:45, 25 January 2009
In pharmacology, colchicine is a "major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (period disease)."[1]
Dosage
Acute gout attack
Initially 1 to 1.2 milligrams, then one of the following until symptoms better or gastrointestinal drug toxicity (stomach pain, vomiting or diarrhea) occur:[2]
- 0.5 to 0.6 milligram every hour
- 1 to 1.2 milligrams every two hours
- 0.5 to 0.6 milligram every 2 to 3 hours
The maximum dose per attack is 4 to 8 milligrams total.
References
- ↑ Anonymous (2024), Colchicine (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Colchicine. In: DRUGDEX® System (Internet database). Greenwood Village, Colo: Thomson Healthcare. Updated periodically.
External references
The most up-to-date information about Colchicine and other drugs can be found at the following sites.
- Colchicine - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Colchicine - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
- Colchicine - Detailed information from DrugBank.