Cerivastatin: Difference between revisions

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(New page: {{subpages}} [[Image:Cerivastatin structure.jpg|right|thumb|350px|{{#ifexist:Template:Cerivastatin structure.jpg/credit|{{Cerivastatin structure.jpg/credit}}<br/>|}}Cerivastatin, a type II...)
 
imported>David E. Volk
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'''Cerivastatin''', sold as '''Lipobay''', '''Rivastatin''' and '''Baycol''', ''now withdrawn from the U.S. and Canadian markets'', is a type II statin formerly used to treat high cholesterol levels ([[hypercholesterolemia]]), prevent [[myocardial infarction|heart attacks]] and [[stroke]]s, and to diminish the formation of [[atherosclerosis|arterial plaque]].  Baycol was voluntarily removed from the U.S. market in August of 2001 by Bayer Pharmaceutical Division due to reports of fatal [[rhabdomyolysis]].
'''Cerivastatin''', sold as '''Lipobay''', '''Rivastatin''' and '''Baycol''', ''now withdrawn from the U.S. and Canadian markets'', is a type II statin formerly used to treat high cholesterol levels ([[hypercholesterolemia]]), prevent [[myocardial infarction|heart attacks]] and [[stroke]]s, and to diminish the formation of [[atherosclerosis|arterial plaque]].  Baycol was voluntarily removed from the U.S. market in August of 2001 by Bayer Pharmaceutical Division due to reports of fatal [[rhabdomyolysis]].
It is a [[Hydroxymethylglutaryl-coenzyme A reductase inhibitor|HMG-CoA reductase inhibitor]] which diminishes the conversion of HMG-CoA to [[mevalonate]], a key chemical precursor of [[cholesterol]].
It is a [[Hydroxymethylglutaryl-coenzyme A reductase inhibitor|HMG-CoA reductase inhibitor]] which diminishes the conversion of HMG-CoA to [[mevalonate]], a key chemical precursor of [[cholesterol]].
It is structurally related to the other [[type II statin]]s, [[fluvastatin]], [[atorvastatin]] and [[rosuvastatin]].
It is structurally related to the other [[type II statin]]s, [[fluvastatin]], [[atorvastatin]] (Lipitor) and [[rosuvastatin]] (Crestor).





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Cerivastatin, a type II statin.

Cerivastatin, sold as Lipobay, Rivastatin and Baycol, now withdrawn from the U.S. and Canadian markets, is a type II statin formerly used to treat high cholesterol levels (hypercholesterolemia), prevent heart attacks and strokes, and to diminish the formation of arterial plaque. Baycol was voluntarily removed from the U.S. market in August of 2001 by Bayer Pharmaceutical Division due to reports of fatal rhabdomyolysis. It is a HMG-CoA reductase inhibitor which diminishes the conversion of HMG-CoA to mevalonate, a key chemical precursor of cholesterol. It is structurally related to the other type II statins, fluvastatin, atorvastatin (Lipitor) and rosuvastatin (Crestor).


brand names

  • Baycol (withdrawn from US and Canadian markets)
  • Lipobay
  • Rivastatin

Drug interactions