Cephalosporin: Difference between revisions
imported>David E. Volk No edit summary |
imported>David E. Volk |
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* [[Cefotetan]] | * [[Cefotetan]] | ||
* [[Cefoxitin]] | * [[Cefoxitin]] | ||
== Third generation cephalosporins == | |||
* [[Cefcapene]] | |||
* [[Cefdaloxime]] | |||
* [[Cefdinir]] | |||
* [[Cefditoren]] | |||
* [[Cefetamet]] | |||
* [[Cefixime]] | |||
* [[Cefmenoxime]] | |||
* [[Cefodizime]] | |||
* [[Cefotaxime]] | |||
* [[Cefpimizole]] | |||
* [[Cefpodoxime]] | |||
* [[Cefteram]] | |||
* [[Ceftibuten]] | |||
* [[Ceftiofur]] | |||
* [[Ceftiolene]] | |||
* [[Ceftizoxime]] | |||
* [[Ceftriaxone]] | |||
* [[Cefoperazone]] | |||
* [[Ceftazidime]] | |||
Revision as of 11:42, 29 April 2008
cephalosporins are a class of antibiotic compounds sharing a common base structure, 7-aminocephalosporanic acid (7-ACA), that was derived from the first cephalosporin discovered, cephalosporin C. Penicillins are very similar, although they contain a five-membered ring in place of the six-membered ring present in the cephalosporin. The activity of cephalosporins, penicillins, and some other antibiotics are due to the presence of a beta-lactam, which binds irreversibly, via acylation, to penicillin-binding proteins, thereby inhibiting the peptidogycan layer of bacterial cell wall synthesis. Cephalosporins are often made semisynthetically.
First generation cephalosporins
- Cefacetrile
- Cefadroxil
- Cefalexin
- Cefaloglycin
- Cefalonium
- Cefaloridine
- Cefalotin
- Cefapirin
- Cefatrizine
- Cefazaflur
- Cefazedone
- Cefazolin
- Cefradine
- Cefroxadine
- Ceftezole
Second generation cephalosporins
In general, second generation cephalosporins have a broader spectrum of activity against Gram-negative bacteria.