Astrocytoma: Difference between revisions

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In neurology and oncology, an astrocytoma is a neoplasm of the central nervous system, which originates in normal astrocytes. Under the 1993 World Health Association criteria, a glioblastoma can be considered a "high-grade" (Grade IV) astrocytoma; grade III anaplastic astrocytomas are also malignant. The lower-grade astrocytomas may progress to higher-grade ^[1]

WHO designation	WHO grade	Kernohan grade	St. Anne/Mayo grade	St. Anne/Mayo criteria
pilocytic astrocytoma	I	I	excluded
Astrocytoma	II	I, II	1 or 2	1: No criteria fulfilled; 2: one criterian, usually nuclear atypia
Anaplastic	II	II, III	3	Two criteria: nuclear atypia and mitosis
Malignant astrocytoma and glioblastoma	IV	III, IV	4	Three or four; add necrosis

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-In [[neurology]] and [[oncology]], an '''astrocytoma'' is a [[neoplasm]] of the [[central nervous system]], which originates in normal [[astrocyte]]s. Under the 1993 [[World Health Association]] criteria, a [[glioblastoma]] can be considered a "high-grade" (Grade IV) astrocytoma; grade III anaplastic astrocytomas are also malignant. The lower-grade astrocytomas may progress to higher-grade <ref>{{citation
+In [[neurology]] and [[oncology]], an '''astrocytoma''' is a [[neoplasm]] of the [[central nervous system]], which originates in normal [[astrocyte]]s. Under the 1993 [[World Health Association]] criteria, a [[glioblastoma]] can be considered a "high-grade" (Grade IV) astrocytoma; grade III anaplastic astrocytomas are also malignant. The lower-grade astrocytomas may progress to higher-grade <ref>{{citation
   | title = The new WHO Classification of Tumors affecting the Central Nervous System
   | author = Stephen B. Tatter