Alpha adrenergic antagonist
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In pharmacology, alpha adrenergic blockers are "drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma."[1] They are also used for benign prostatic hyperplasia.
Naftopidil is more selective for the alpha-1a adrenergic receptor and has been used to treat benign prostatic hyperplasia.[2]
Costs
According to drugstore.com:
- Alfuzosin (Uroxatral) 10 mg - $121.85 for 30 tablets
- Doxasozin
- Naftopidil
- Prazosin (Minipress) 5 mg - $33.99 for 60 tablets
- Tamsulosin (Flomax) 0.4 - $142.19 for 30 tablets
- Terazosin
References
- ↑ Anonymous (2024), Alpha adrenergic antagonist (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Garimella PS, Fink HA, Macdonald R, Wilt TJ (2009). "Naftopidil for the treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia.". Cochrane Database Syst Rev (4): CD007360. DOI:10.1002/14651858.CD007360.pub2. PMID 19821408. Research Blogging.