Desloratadine

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Desloratadine.png
Desloratadine
IUPAC name: 8-chloro-6,11-dihydro-11-(4-piperdinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Synonyms: Clarinex
Formula: C19H19Cl4N2

 Uses: rhinitis, urticaria, puritis, hives

 Properties: tricyclic histamine antagonist

 Hazards:

Mass (g/mol): CAS #:
310.8


Desloratadine (Clarinex) is a light blue tablet used as an anahistamine and are available by prescription only in the United States. Each tablet contains 5 milligrams desloratadine which are taken orally (by mouth). The powder is white to off-white and is slightly soluble in water. It is very soluble in ethanol andpropylene glycol. The molecular weight for Clarinex (Desloratadine) is 310.8. It is a long acting tricyclic histamine antagonist with selective H1-receptor histamine antagonist activity.

Usage

Patients 12 and older can take 5 milligrams of Clarinex once daily to help alleviate allergic rhinitis symptoms including both nasal and non-nasal symptoms. Clarinex can also be used to treat hives (uticaria).

Pregnancy and lactation

Clarinex is classified as a class C drug by the Federal Drug Administration. The drug does pass through breast milk.

Reported adverse affects

Clarinex had a 2 percent or greater incidence of the following adverse side affects which include: pharyngitis, dry mouth, myalgia, fatigue, somnolence, dysmenorrhea in that order.

Overdose

Follow standard treatments to remove the unabsorbed drug and provide supportive care. Clarinex is not removed through hemodyalisis. [1]

References

  1. Clarinex (Desloratadine) (PDF). Retrieved on 2011-05-22.

The most up-to-date information about Desloratadine and other drugs can be found at the following sites.