Hypothyroidism
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In medicine, hypothyroidism is "a syndrome that results from abnormally low secretion of thyroid hormones from the thyroid gland, leading to a decrease in basal metabolic rate. In its most severe form, there is accumulation of mucopolysaccharides in the skin and edema, known as myxedema."[1]
Thyroid stimulating hormone levels of less than 10 may not be important.[2]
Diagnosis
Symptoms
Symptoms may not be accurate.[3][4] The symptoms that may be distinguish between hypothyroid and normal patients are hoarse voice, dry skin, and muscle cramps.[4]
Treatment
About thirty[5] to forty[3][6] percent of patients taking thyroid hormone replacement may not have appropriate values of thyroid stimulating hormone (TSH).
Taking replacement hormone at night may be better.[7]
References
- ↑ Anonymous (2024), Hypothyroidism (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Rodondi N, den Elzen WP, Bauer DC, Cappola AR, Razvi S, Walsh JP et al. (2010). "Subclinical hypothyroidism and the risk of coronary heart disease and mortality.". JAMA 304 (12): 1365-74. DOI:10.1001/jama.2010.1361. PMID 20858880. Research Blogging.
- ↑ 3.0 3.1 Canaris GJ, Manowitz NR, Mayor G, Ridgway EC (2000). "The Colorado thyroid disease prevalence study.". Arch Intern Med 160 (4): 526-34. PMID 10695693. [e]
- ↑ 4.0 4.1 Canaris GJ, Steiner JF, Ridgway EC (1997). "Do traditional symptoms of hypothyroidism correlate with biochemical disease?". J Gen Intern Med 12 (9): 544-50. DOI:10.1046/j.1525-1497.1997.07109.x. PMID 9294788. PMC PMC1497160. Research Blogging.
- ↑ Ross DS, Daniels GH, Gouveia D (1990). "The use and limitations of a chemiluminescent thyrotropin assay as a single thyroid function test in an out-patient endocrine clinic.". J Clin Endocrinol Metab 71 (3): 764-9. PMID 2394778. [e]
- ↑ Okosieme OE, Belludi G, Spittle K, Kadiyala R, Richards J (2011). "Adequacy of thyroid hormone replacement in a general population.". QJM 104 (5): 395-401. DOI:10.1093/qjmed/hcq222. PMID 21109503. Research Blogging.
- ↑ Bolk N, Visser TJ, Nijman J, Jongste IJ, Tijssen JG, Berghout A (2010). "Effects of evening vs morning levothyroxine intake: a randomized double-blind crossover trial.". Arch Intern Med 170 (22): 1996-2003. DOI:10.1001/archinternmed.2010.436. PMID 21149757. Research Blogging.