Aripiprazole

In medicine, aripiprazole (pronunciation: ay ri pip' ray zole) is an atypical or second generation anti-psychotic agent that "has both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D₂ receptor antagonistic activity; structure given in first source; use associated with hyperglycemia."

In the United States, the Food and Drug Administration has approved the use of aripiprazole for the treatment of schizophrenia, bipolar I disorder, major depressive disorder, irritability associated with autistic disorder agitation associated with schizophrenia or mania from bipolar disorder. The trade name is Abilify®. Although not approved for the treatment of dementia, aripiprazole has been studied in this setting.