Bisphosphonate
Jump to navigation
Jump to search
In medicine, bisphosphonates are medications which "contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents."[1]
Bisphosphonates are used to prevent fractures among patients with osteoporosis or low bone mass.
Examples of bisphosphonates include alendronate, risedronate, etidronate, ibandronate, pamidronate, and zoledronic acid.
Adverse effects
Zoledronic acid can increase atrial fibrillation.[2]
References
- ↑ Anonymous (2024), Bisphosphonate (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Black DM, Delmas PD, Eastell R, et al. (May 2007). "Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis". N. Engl. J. Med. 356 (18): 1809–22. DOI:10.1056/NEJMoa067312. PMID 17476007. Research Blogging.