Staphylococcus epidermidis

From Citizendium
Revision as of 15:48, 20 April 2009 by imported>Sarah M. Maurice (→‎Pathology)
Jump to navigation Jump to search

Template:TOC-left

All unapproved Citizendium articles may contain errors of fact, bias, grammar etc. A version of an article is unapproved unless it is marked as citable with a dedicated green template at the top of the page, as in this version of the 'Biology' article. Citable articles are intended to be of reasonably high quality. The participants in the Citizendium project make no representations about the reliability of Citizendium articles or, generally, their suitability for any purpose.

Attention niels epting.png
Attention niels epting.png
This article is currently being developed as part of an Eduzendium student project in the framework of a course entitled Microbiology 201 at Queens College, CUNY. The course homepage can be found at CZ:Biol 201: General Microbiology.
For the course duration, the article is closed to outside editing. Of course you can always leave comments on the discussion page. The anticipated date of course completion is May 21, 2009. One month after that date at the latest, this notice shall be removed.
Besides, many other Citizendium articles welcome your collaboration!


Staphylococcus epidermidis
Staphy.jpg
Scientific classification
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Bacillales
Family: Staphylococcacea
Genus: Staphylococcus
Species: S. epidermidis
Binomial name
Staphylococcus epidermidis


Description and significance

Staphylococcus epidermidis is a gram positive coccus, a normal inhabitant of the human skin that grows in clusters. It is an aerobic organism but is yet capable of growing anaerobically when placed in a standardized, complex medium of glucose. Research studies reveal that S. epidermidis lives in close association with S. aureus, a very destructive pathogen.

Even though a coagulase-negative gram bacterium, S. epidermidis has been lately classified among the most important pathogens responsible for divers nosocomial infections. Most strains are highly resistant to multiple antibiotics, such as penicillin, tetracycline, methicillin and many more, which makes it very difficult to treat the infections resulting from these bacteria. According to the Centers for Disease Control and Prevention's National Nosocomial infection surveillance system, S. epidermidis is responsible for 33.5% of nosocomial blood stream infections.

Genome structure

Cell structure and metabolism

Ecology

Pathology

Most infections caused by S. epidermidis affect hospital patients because these organisms develop structures called biofilms on the surface of implanted medical devices. These biofilms result from the agglomeration of bacterial cells that are contained in an exopolysaccharide matrix, the slime, to produce a very dense and protected environment from the host defense systems and antibiotics. They not only provide protection from the host but they also result in the damage of surrounding tissues of the host. Skin and tissues infections, post-surgical wounds are the common points of entry for infection by S. epidermis. This bacterium accounts for most catheter-related infections, joint replacement infections, the majority of prosthetic cardiac valve infections and infections following postneurosurgical procedures.

Application to Biotechnology

Current Research

References