MELD Score

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The MELD score can help predict mortality in patients with cirrhosis and end-stage liver disease.

Calculation

The equation is:

An online calculator is available.

Interpretation

In interpeting the MELD Score in hospitalized patients, the 3 month mortality is:[1]

  • 40 or more - 100% mortality
  • 30-39 - 83% mortality
  • 20-29 - 76% mortality
  • 10-19 - 27% mortality
  • <10 - 4% mortality

The MELD has also been studied in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS).[2]

In preoperative care, the MELD Score can help predict complications of surgery among patients with cirrhosis.[3] The MELD Score may [4] or may not[5] perform better than the Child-Turcotte-Pugh class.

References

  1. Kamath PS, Wiesner RH, Malinchoc M, et al (2001). "A model to predict survival in patients with end-stage liver disease". Hepatology 33 (2): 464–70. DOI:10.1053/jhep.2001.22172. PMID 11172350. Research Blogging.
  2. Malinchoc M, Kamath PS, Gordon FD, Peine CJ, Rank J, ter Borg PC (2000). "A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts". Hepatology 31 (4): 864–71. DOI:10.1053/he.2000.5852. PMID 10733541. Research Blogging.
  3. Teh SH, Nagorney DM, Stevens SR, et al (April 2007). "Risk factors for mortality after surgery in patients with cirrhosis". Gastroenterology 132 (4): 1261–9. DOI:10.1053/j.gastro.2007.01.040. PMID 17408652. Research Blogging.
  4. Farnsworth N, Fagan SP, Berger DH, Awad SS (November 2004). "Child-Turcotte-Pugh versus MELD score as a predictor of outcome after elective and emergent surgery in cirrhotic patients". Am. J. Surg. 188 (5): 580–3. DOI:10.1016/j.amjsurg.2004.07.034. PMID 15546574. Research Blogging.
  5. Suman A, Barnes DS, Zein NN, Levinthal GN, Connor JT, Carey WD (August 2004). "Predicting outcome after cardiac surgery in patients with cirrhosis: a comparison of Child-Pugh and MELD scores". Clin. Gastroenterol. Hepatol. 2 (8): 719–23. PMID 15290666[e]

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