Insulin resistance
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- See: Article on insulin, if necessary, to better understand present article.
--- As described in the 2013 Medical Subject Headings of the National Library of Medicine, insulin resistance consists of
- Diminished effectiveness of insulin in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent hyperglycemia or ketosis.[1]
It can be caused by the presence of insulin antibodies or the abnormalities in insulin receptors (receptor, insulin) on target cell surfaces. It is often associated with obesity; diabetic ketoacidosis; infection; and certain rare conditions.
Insulin resistance (HOMA-IR) can be measured by:[2]
References
- ↑ Anonymous (2024), Insulin resistance (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985). "Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man". Diabetologia 28: 412–9. PMID 3899825. [e]