File:NMDA receptor.jpg
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Summary
| Title / Description
|
Activation (i.e., excitation) occurs when either glutamate (Glu) or N-methyl-d-aspartate (NMDA) and glycine (Gly) bind to the receptor molecule. A channel within the receptor complex enables molecules to cross the cell membrane. Magnesium (Mg) blocks this channel. When Mg is removed from the channel and the receptor is activated, calcium (Ca++) and sodium (Na+) ions enter the cell and potassium ions (K+) leave. MK-801 prevents the flow of ions across the membrane by binding to a site within the ion channel, thereby blocking NMDA receptor function and protecting the cell against excess activation (i.e., excitotoxicity). |
|---|---|
| Author(s)
|
J.D. Thomas and E.P. Riley |
| Copyright holder
|
National Institute on Alcohol Abuse and Alcoholism See below for license/re-use information. |
| Source
|
http://www.niaaa.nih.gov/Resources/GraphicsGallery/Neuroscience/221p51.htm |
| Date created
|
1998 |
| Country of first publication
|
United States |
| Notes
|
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|
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Licensing/Copyright status
This media, NMDA receptor.jpg, is in the public domain
This is a work of the United States Government, and as such is not afforded copyright protection under US law.
For further information see Title 17, Chapter 1, Section 105 of the US Code.
You may freely copy, distribute, display and perform this work, as well as make derivative and commercial works.
File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 18:56, 11 March 2022 | | 788 × 508 (67 KB) | Maintenance script (talk | contribs) | == Summary == Importing file |
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