Erythrocyte transfusion: Difference between revisions
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==Adverse effects== | ==Adverse effects== | ||
{{main|Transfusion reaction}} | {{main|Transfusion reaction}} | ||
===Immunologic reactions=== | |||
* '''Febrile nonhemolytic transfusion reactions (FNHTR)''' due to destruction of incompatible donor white blood cells | |||
* '''Hemolytic reactions''' due to [[blood group incompatibility]] is "mismatch between donor and recipient blood. [[Antibody|Antibodies]] present in the recipient's serum are directed against [[antigen]]s in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed."<ref>{{MeSH|Blood group incompatibility}}</ref> | |||
** Acute hemolytic transfusion reactions due to ABO incompatibility | |||
** Delayed hemolytic transfusion reactions | |||
* '''Allergic reactions''' | |||
** Anaphylactic transfusion reactions may occur, especially in patients with IgA-deficiency. | |||
** Urticaria may occur due to the recipient's IgE reacting to antigens from the donor. | |||
* '''Posttransfusion purpura (PTP)''' due to thrombocytopenia from platelet antibodies. This is more common in women who have been pregnant. | |||
* Transfusion associated '''graft-versus-host disease''' (TA-GVHD) | |||
==References== | ==References== | ||
Revision as of 21:16, 6 November 2008
In medicine, erythrocyte transfusion or red blood cell transfusion is the "transfer of erythrocytes from a donor to a recipient or reinfusion to the donor."[1]
Adverse effects
Immunologic reactions
- Febrile nonhemolytic transfusion reactions (FNHTR) due to destruction of incompatible donor white blood cells
- Hemolytic reactions due to blood group incompatibility is "mismatch between donor and recipient blood. Antibodies present in the recipient's serum are directed against antigens in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed."[2]
- Acute hemolytic transfusion reactions due to ABO incompatibility
- Delayed hemolytic transfusion reactions
- Allergic reactions
- Anaphylactic transfusion reactions may occur, especially in patients with IgA-deficiency.
- Urticaria may occur due to the recipient's IgE reacting to antigens from the donor.
- Posttransfusion purpura (PTP) due to thrombocytopenia from platelet antibodies. This is more common in women who have been pregnant.
- Transfusion associated graft-versus-host disease (TA-GVHD)
References
- ↑ Anonymous (2024), Erythrocyte transfusion (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Anonymous (2024), Blood group incompatibility (English). Medical Subject Headings. U.S. National Library of Medicine.