Herniated disk: Difference between revisions

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==Treatment==
==Treatment==
[[Randomized controlled trial]]s address discectomy versus conservative care:
[[Randomized controlled trial]]s address diskectomy versus conservative care.
*  The Leiden-The Hague Spine Intervention Prognostic Study of 283 patients found that surgery led to quicker improvement at one year<ref name="pmid17538084">{{cite journal |author=Peul WC, van Houwelingen HC, van den Hout WB, ''et al'' |title=Surgery versus prolonged conservative treatment for sciatica |journal=The New England journal of medicine |volume=356 |issue=22 |pages=2245–56 |year=2007 |month=May |pmid=17538084 |doi=10.1056/NEJMoa064039 |url=http://content.nejm.org/cgi/pmidlookup?view=short&pmid=17538084&promo=ONFLNS19 |issn=}}</ref>, with no further changes after two years.<ref>Peul WC, Hout WB, Brand R, Thomeer RT, Koes BW; for the Leiden-The Hague Spine Intervention Prognostic Study Group. Prolonged conservative care versus early surgery in patients with sciatica caused by lumbar disc herniation: two year results of a randomised controlled trial. BMJ. 2008 May 23. PMID 18502911</ref> The cost of surgery might be acceptable to some patients.<ref>Hout WB, Peul WC, Koes BW, Brand R, Kievit J, Thomeer RT; for the Leiden-The Hague Spine Intervention Prognostic Study Group. Prolonged conservative care versus early surgery in patients with sciatica from lumbar disc herniation: cost utility analysis alongside a randomised controlled trial. BMJ. 2008 May 23. PMID 18502912</ref>
 
* The Spine Patient Outcomes Research Trial (SPORT) of 501 patients found "patients in both the surgery and the nonoperative treatment groups improved  substantially over a 2-year period. Because of the large numbers of patients who crossed over in both directions, conclusions about the superiority or  equivalence of the treatments are not warranted based on the intent-to-treat  analysis."<ref name="pmid17119140">{{cite journal |author=Weinstein JN, Tosteson TD, Lurie JD, ''et al'' |title=Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trial |journal=JAMA : the journal of the American Medical Association |volume=296 |issue=20 |pages=2441–50 |year=2006 |month=November |pmid=17119140 |pmc=2553805 |doi=10.1001/jama.296.20.2441 |url=http://jama.ama-assn.org/cgi/pmidlookup?view=long&pmid=17119140 |issn=}}</ref><ref name="pmid17119141">{{cite journal |author=Weinstein JN, Lurie JD, Tosteson TD, ''et al'' |title=Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT) observational cohort |journal=JAMA : the journal of the American Medical Association |volume=296 |issue=20 |pages=2451–9 |year=2006 |month=November |pmid=17119141 |pmc=2562254 |doi=10.1001/jama.296.20.2451 |url=http://jama.ama-assn.org/cgi/pmidlookup?view=long&pmid=17119141 |issn=}}</ref> The costs may be acceptable.<ref name="pmid18777603">{{cite journal |author=Tosteson AN, Skinner JS, Tosteson TD, ''et al'' |title=The cost effectiveness of surgical versus nonoperative treatment for lumbar disc herniation over two years: evidence from the Spine Patient Outcomes Research Trial (SPORT) |journal=Spine |volume=33 |issue=19 |pages=2108–15 |year=2008 |month=September |pmid=18777603 |doi= |url= |issn=}}</ref>
===Microdiskectomy===
The Leiden-The Hague Spine Intervention Prognostic Study of 283 patients found that microdiskectomy led to quicker improvement at one year<ref name="pmid17538084">{{cite journal |author=Peul WC, van Houwelingen HC, van den Hout WB, ''et al'' |title=Surgery versus prolonged conservative treatment for sciatica |journal=The New England journal of medicine |volume=356 |issue=22 |pages=2245–56 |year=2007 |month=May |pmid=17538084 |doi=10.1056/NEJMoa064039 |url=http://content.nejm.org/cgi/pmidlookup?view=short&pmid=17538084&promo=ONFLNS19 |issn=}}</ref>, with no further changes after two years.<ref>Peul WC, Hout WB, Brand R, Thomeer RT, Koes BW; for the Leiden-The Hague Spine Intervention Prognostic Study Group. Prolonged conservative care versus early surgery in patients with sciatica caused by lumbar disc herniation: two year results of a randomised controlled trial. BMJ. 2008 May 23. PMID 18502911</ref> The cost of surgery might be acceptable to some patients.<ref>Hout WB, Peul WC, Koes BW, Brand R, Kievit J, Thomeer RT; for the Leiden-The Hague Spine Intervention Prognostic Study Group. Prolonged conservative care versus early surgery in patients with sciatica from lumbar disc herniation: cost utility analysis alongside a randomised controlled trial. BMJ. 2008 May 23. PMID 18502912</ref>
 
===Open diskectomy===
The Spine Patient Outcomes Research Trial (SPORT) of 501 patients found "patients in both the surgery and the nonoperative treatment groups improved  substantially over a 2-year period. Because of the large numbers of patients who crossed over in both directions, conclusions about the superiority or  equivalence of the treatments are not warranted based on the intent-to-treat  analysis."<ref name="pmid17119140">{{cite journal |author=Weinstein JN, Tosteson TD, Lurie JD, ''et al'' |title=Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trial |journal=JAMA : the journal of the American Medical Association |volume=296 |issue=20 |pages=2441–50 |year=2006 |month=November |pmid=17119140 |pmc=2553805 |doi=10.1001/jama.296.20.2441 |url=http://jama.ama-assn.org/cgi/pmidlookup?view=long&pmid=17119140 |issn=}}</ref><ref name="pmid17119141">{{cite journal |author=Weinstein JN, Lurie JD, Tosteson TD, ''et al'' |title=Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT) observational cohort |journal=JAMA : the journal of the American Medical Association |volume=296 |issue=20 |pages=2451–9 |year=2006 |month=November |pmid=17119141 |pmc=2562254 |doi=10.1001/jama.296.20.2451 |url=http://jama.ama-assn.org/cgi/pmidlookup?view=long&pmid=17119141 |issn=}}</ref> The costs may be acceptable.<ref name="pmid18777603">{{cite journal |author=Tosteson AN, Skinner JS, Tosteson TD, ''et al'' |title=The cost effectiveness of surgical versus nonoperative treatment for lumbar disc herniation over two years: evidence from the Spine Patient Outcomes Research Trial (SPORT) |journal=Spine |volume=33 |issue=19 |pages=2108–15 |year=2008 |month=September |pmid=18777603 |doi= |url= |issn=}}</ref>


==References==
==References==

Revision as of 20:32, 17 June 2009

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In medicine, a herniated disk is defined as an "intervertebral disk in which the nucleus pulposus has protruded through surrounding fibrocartilage. This occurs most frequently in the lower lumbar region.".[1]

A herniated disk is an infrequent, but important cause of low back pain. A herniated disk is more likely when sciatica is present.

Diagnosis

History and physical examination

The presence of sciatica is associated with a herniated disk:[2]

On physical examination, a positive straight leg raise is associated with a herniated disk:[2]

Treatment

Randomized controlled trials address diskectomy versus conservative care.

Microdiskectomy

The Leiden-The Hague Spine Intervention Prognostic Study of 283 patients found that microdiskectomy led to quicker improvement at one year[3], with no further changes after two years.[4] The cost of surgery might be acceptable to some patients.[5]

Open diskectomy

The Spine Patient Outcomes Research Trial (SPORT) of 501 patients found "patients in both the surgery and the nonoperative treatment groups improved substantially over a 2-year period. Because of the large numbers of patients who crossed over in both directions, conclusions about the superiority or equivalence of the treatments are not warranted based on the intent-to-treat analysis."[6][7] The costs may be acceptable.[8]

References

  1. ↑ National Library of Medicine. Intervertebral Disk Displacement. Retrieved on 2007-11-13.
  2. ↑ 2.0 2.1 Deyo RA, Rainville J, Kent DL (1992). "What can the history and physical examination tell us about low back pain?". JAMA 268 (6): 760–5. PMID 1386391. [e]
  3. ↑ Peul WC, van Houwelingen HC, van den Hout WB, et al (May 2007). "Surgery versus prolonged conservative treatment for sciatica". The New England journal of medicine 356 (22): 2245–56. DOI:10.1056/NEJMoa064039. PMID 17538084. Research Blogging.
  4. ↑ Peul WC, Hout WB, Brand R, Thomeer RT, Koes BW; for the Leiden-The Hague Spine Intervention Prognostic Study Group. Prolonged conservative care versus early surgery in patients with sciatica caused by lumbar disc herniation: two year results of a randomised controlled trial. BMJ. 2008 May 23. PMID 18502911
  5. ↑ Hout WB, Peul WC, Koes BW, Brand R, Kievit J, Thomeer RT; for the Leiden-The Hague Spine Intervention Prognostic Study Group. Prolonged conservative care versus early surgery in patients with sciatica from lumbar disc herniation: cost utility analysis alongside a randomised controlled trial. BMJ. 2008 May 23. PMID 18502912
  6. ↑ Weinstein JN, Tosteson TD, Lurie JD, et al (November 2006). "Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trial". JAMA : the journal of the American Medical Association 296 (20): 2441–50. DOI:10.1001/jama.296.20.2441. PMID 17119140. PMC 2553805. Research Blogging.
  7. ↑ Weinstein JN, Lurie JD, Tosteson TD, et al (November 2006). "Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT) observational cohort". JAMA : the journal of the American Medical Association 296 (20): 2451–9. DOI:10.1001/jama.296.20.2451. PMID 17119141. PMC 2562254. Research Blogging.
  8. ↑ Tosteson AN, Skinner JS, Tosteson TD, et al (September 2008). "The cost effectiveness of surgical versus nonoperative treatment for lumbar disc herniation over two years: evidence from the Spine Patient Outcomes Research Trial (SPORT)". Spine 33 (19): 2108–15. PMID 18777603. [e]
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