Hypertension: Difference between revisions

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==Definition==
==Definition==
==Classification==
{| class="wikitable"
|+ Classification of blood pressure for adults
! Blood pressure classification !! colspan=2 Initial blood pressure (mm Hg) !! Followup recommended
|-
|  || SBP || DBP ||
|-
| Normal || <120 || <80 || Recheck in 2 years
|-
| Prehypertension || <140 || <90 || Recheck in 1 year‡
|-
| Stage 1 Hypertension || <160 || <100 || Confirm within 2 months
|-
| Stage 2 Hypertension || <u>></u>160 || <u>></u>100 || "Evaluate or refer to source of care within 1 month. For those
with higher pressures (e.g., >180/110 mmHg), evaluate and treat immediately or within 1 week depending on clinical
situation and complications."
|}
==Epidemiology==
==Epidemiology==
==Etiology==
==Etiology==

Revision as of 17:23, 22 October 2007

Hypertension is a multisystem disease whose hallmark is the elevation of blood pressure.

Definition

Classification

Classification of blood pressure for adults
Blood pressure classification colspan=2 Initial blood pressure (mm Hg) Followup recommended
SBP DBP
Normal <120 <80 Recheck in 2 years
Prehypertension <140 <90 Recheck in 1 year‡
Stage 1 Hypertension <160 <100 Confirm within 2 months
Stage 2 Hypertension >160 >100 "Evaluate or refer to source of care within 1 month. For those

with higher pressures (e.g., >180/110 mmHg), evaluate and treat immediately or within 1 week depending on clinical situation and complications."


Epidemiology

Etiology

Pathophysiology

Diagnosis & Natural History

Treatment

Current clinical practice guidelines are based on The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7).[1]

Treatment goals

Per the JNC7 Guidelines:[1]

  • "Treating "most patients" SBP and DBP to targets that are <140/90 mmHg is associated with a decrease in cardiovascular complications.
  • In patients with hypertension and diabetes or renal disease, the BP goal is <130/80 mmHg.

Initial medication

Several randomized controlled trials have compared initial medications for hypertension.[2][3][4][5] For patients with Stage 2 Hypertension (SBP >160 or DBP>100 mmHg), start with two drugs.[1]

Systolic hypertension

For more information, see: Systolic hypertension.


References

  1. 1.0 1.1 1.2 Chobanian AV, Bakris GL, Black HR, et al (2003). "The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report". JAMA 289 (19): 2560-72. DOI:10.1001/jama.289.19.2560. PMID 12748199. Research Blogging. http://www.nhlbi.nih.gov/guidelines/hypertension/jnc7full.pdf
  2. ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (2002). "Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)". JAMA 288 (23): 2981-97. PMID 12479763[e]
  3. Wing LM, Reid CM, Ryan P, et al (2003). "A comparison of outcomes with angiotensin-converting--enzyme inhibitors and diuretics for hypertension in the elderly". N. Engl. J. Med. 348 (7): 583-92. DOI:10.1056/NEJMoa021716. PMID 12584366. Research Blogging.
  4. Materson BJ, Reda DJ, Cushman WC, et al (1993). "Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents". N. Engl. J. Med. 328 (13): 914-21. PMID 8446138[e]
  5. Materson BJ, Reda DJ (1994). "Correction: single-drug therapy for hypertension in men". N. Engl. J. Med. 330 (23): 1689. PMID 8177286[e]