Talk:Homeopathy/Archive 13: Difference between revisions

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imported>Howard C. Berkowitz
(Your point about pointlessness is absolutely, sharply on point, and I hope it points to a pattern of condescending lectures about me, as opposed to the topic.)
imported>Howard C. Berkowitz
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== Notable information and formidible [sic] survey  ==
==APPROVED Version 1.1==  


Interesting. The content added followed a market research document about popularity, with no indications of effectiveness to go with the popularity. The BMJ citation speaks of actions, with no rationale or outcomes data. How about some indications not of the popularity of these referrals, not of the hypothesized mechanisms of homeopathy, but of the outcomes of these referrals? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 00:28, 10 October 2008 (CDT)
<div class="usermessage plainlinks">Discussion for Version 1.1 stopped here. Please continue further discussion under this break. </div>


: Your comment reminds me of skeptics who expect controlled clinical research reports to explain "mechanism of action." Clinical studies are clinical studies. They report results, not theories or explanations about how homeopathics work or may work. Likewise, surveys ask some questions, not all questions.  I cannot help but sense that you don't want this information because it suggests greater popularity about homeopathy that you don't want to accept. There is no doubt (!) about the notability about the BMJ article, and the market research survey seems to confirm and expand upon what the BMJ reported.  [[User:Dana Ullman|Dana Ullman]] 16:29, 11 October 2008 (UTC)
The Approval includes two copyedits [http://en.citizendium.org/wiki?title=Homeopathy&diff=100587554&oldid=100587549] [[User:Hayford Peirce|Hayford Peirce]] 19:13, 11 October 2009 (UTC)


::"Skeptic", as you use the term, Dana, is something that, whether you intend it to be or not, is becoming offensive. "Sensing" my reasons is offensive, and, I believe, something you have been asked not to do. If you "sense" I am doing something, let me suggest a novel diagnostic technique: ask me, in so many words, to explain my reasoning. That, incidentally, is considered a professional means of collaborative editing.
:I'm not sure how to add yet another archive and get things to show up properly in the header here. Could someone do so? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 19:22, 11 October 2009 (UTC)


::Given that my comment specifically said "not of the <u>hypothesized mechanisms</u> of homeopathy, but of the <u>outcomes</u> of these referrals", why are you raising the question about [[randomized controlled trial]]s (RCT) and mechanism of action? In point of fact, most RCT do not define mechanisms of action. In the U.S., when the investigators make the initial application for human subject research to their Institutional Review Board, and (usual sequence) then to the [[Food and Drug Administration]] for the Investigational New Drug Application (IND) that grants additional permissions, they will present a proposed experimental protocol as part of those applications. It is <u>those</u> applications that will contain the best understanding of the mechanism of action, which, with current methods, is apt to come from ''in vitro'' or animal models. In some cases, it may use human data from a human subject trial for pure research, which thus goes to the IRB but not the FDA.  
== Beginning with semi-lower-case editorial... ==


::Certainly, additional insight into mechanisms may come from clinical trials, but that is not their major intent. The intent of phase II and phase III is to demonstrate efficacy, which is an aspect of the question I asked, not the one you assumed I asked, about outcomes.
As a first step, I'm going to all footnotes that contain other than bibliographic material or definitions, and either moving the substantive text into the main article, or, in some cases, linking to a subarticle.


::As to popularity, cigarettes are more popular than medicine, to say nothing of television. There is no "popularity" section in the article on [[medicine]]. Speaking editorially, popularity, in general, would be appropriate for the Sociology Workgroup, or for groups dealing with popular culture. I don't see a strong reason for it in something where we are concerned not with social behavior, but effectiveness of health methods.
While it may be reasonable, in a printed book or journal, to have bottom-of-the-page notes, in this format, the content of the notes will not be seen unless the reader clicks on them. How many readers do that?  In effect, the text is being hidden. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 19:37, 11 October 2009 (UTC)


::The market research study is not from an authoritative source by the standards of Wikipedia, and it should be deleted. I intend to do so unless I am overruled, or you come up with more data on its methodology and why the market research group should be considered as credible as the BMJ. That it is consistent with the BMJ report is no more authoritative than a television talking-head arguing about a political speech, unless it passes the criteria for peer-reviewed or otherwise authoritative sources. CZ generally accepts books from reputable publishers, which usually involves review. Not everything has to come from a journal.
== A balanced blog post on the subject ==


::Apropos of the BMJ study, I note its date was 1994. You deleted several references I had inserted (see below) on the grounds there were "more recent" studies. The earliest of those studies, however, was 2001, and you have supported a number of quotes from 1905 and earlier, so date alone does not justify deletion. These particular trials were notable in another way, which I shall make even clearer when I reinsert them: they were the first homeopathic trials funded by NCCAM, or peer-reviewed secondary sources abut them. The principal investigator on each was Iris Rose, on the faculty of the University of Arizona and both an MD and homeopathically qualified. Since I cite some of her later publications, I believe it appropriate to establish her pattern of being funded and able to qualify for additional funding. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:14, 11 October 2008 (UTC)
can be found [http://scienceblogs.com/neurotopia/2009/12/homeopathy_the_basics.php here]. --[[User:Daniel Mietchen|Daniel Mietchen]] 09:21, 16 December 2009 (UTC)
<nowiki><ref name=NCCAM-FM>{{citation
| title = Homeopaths Conduct Groundbreaking NIH Fibromyalgia Study
| journal = Townsend Letter for Doctors and Patients
| date = April 2001 
| url = http://findarticles.com/p/articles/mi_m0ISW/is_/ai_72297189}}</ref> <ref name=Bell2004>{{citation
| title = EEG alpha sensitization in individualized homeopathic treatment of fibromyalgia
| author = Bell IR; Lewis DA; Lewis SE; Schwartz GE; Brooks AJ; Scott A; Baldwin CM
| journal = Int J Neurosci
| year = 2004
| volume = 114(9)
| pages = 1195-220
| url = http://www.medscape.com/medline/abstract/15370183}}</ref>  A 2003 review of CAM methods for fibromyalgia found the most effective methods were "acupuncture, some herbal and nutritional supplements (magnesium, SAMe) and massage therapy"; there were positive results but methodological problems with a study on homeopathy.<ref name=>{{citation
| title = Complementary and alternative medicine in fibromyalgia and related syndromes
| journal = Best Pract Res Clin Rheumatol
| year =2003
| volume = 17(4)
| pages = 667-83
| author = Holdcraft LC; Assefi N; Buchwald D
| url = http://www.medscape.com/medline/abstract/12849718}}</ref></nowiki>


: Howard, I believe that your desire to not allow the BMJ article about the use and status of homeopathy by doctors in Europe because it does not provide information on what was the result of the use of the medicines or what was the result of the referrals borders on the ridiculousYes, it is that bad.  I am not saying that your desire for this information is bad or wrong; what I am saying is that the BMJ survey information is notable, but just because the survey doesn't provide this information does not make it less notable.  I do appreciate some of your contributions, but I seriously question others, such as the ones above in this section.  If you happen to have more recent survey information, please provide it. If not, this survey information still provides value. I did delete some older articles because there were newer studies.  The 2003 review of CAM methods did not account for the high quality homeopathic trial on fibromyalgia published in 2004 (by Iris Bell, not Iris Rose). For the record, I am not against information in this article that is negative nor do I want it simply in the skeptics' section. I simply do not want misinformation, and Killen's statement was clearly misinformed. [[User:Dana Ullman|Dana Ullman]] 18:09, 12 October 2008 (UTC)
:I added a comment, as did PaulTruly delightful, however, is <blockquote>Personally, I would really like to see a homeopathic treatment for dehydration. You'd have to have a compound that causes dehydration, but what would you dilute it in? you can't dilute it in water or saline, because those will rehydrate, and in homeopathy, you have to CAUSE dehydration to cure it...but you can't having anything that CAUSES dehydration because it would have to be diluted to the point where none of the dehydrating agent remains...</blockquote>


::The article "does not provide information of what was the result of the use of the medicines"? Then what information does it convey? Your beliefs about my desires are not authoritative, and it is insulting that you think you know them better than I do.
:It should be noted that some camping supply stores, in the same aisle as freeze-dried foods, offer cans of "dehydrated water". Ethical staff makes sure that new users understand the purpose of same. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 15:06, 16 December 2009 (UTC)


::You may do as you will with popularity survey data, but I consider it completely irrelevant to any article in which popularity is not the dominant factor, such as an illection. Killen's statement was the statement of an official in a relevant government agency. Whether it is misinformed or not makes no difference, as it implies a policy. Politicians routinely say misinformed things, but they don't have the opportunity to have it removed. I have yet to hear any substantive reason on why it was a misinformed statement, other than it does not agree with your definition of homeopathy.


::When a neutral editor is involved with the article, I shall ask to have the Killen statement replaced, as a matter of historical record that an official of NCCAM said it.[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 03:08, 17 October 2008 (UTC)
Howard, you gave the wrong link for Sympathetic magic. It's http://en.citizendium.org/wiki/Sympathetic_magic  And make sure the period at the end does not get connected to the link. [[User:Chris Day|Chris Day]] 15:26, 16 December 2009 (UTC)


== Reason for reverting "other compounds" ==
That's a reasonable way to look at it, which is unusual for a blog. [[User:D. Matt Innis|D. Matt Innis]] 18:43, 16 December 2009 (UTC)


In an earlier version, the homeopathic remedies were described as small quantities of an ingredient "dissolved" in "water, ethanol and/or other compounds". Dana changed this to "water or ethanol" with an edit note to be more accurate.
::Put it into the External Links. --[[User:Daniel Mietchen|Daniel Mietchen]] 19:27, 16 December 2009 (UTC)


Among other compounds are quartz and lactose, mentioned elsewhere in the article, for ingredients that are insoluble in water or ethanol. If these other compounds are no longer used, the article should reflect the reason they were no longer used, which might be interesting and relevant on how homeopathy refines its methods.
== Ramanand's changes  ==


Let's assume they are not used, but ethanol is. Is there an assertion and supporting evidence that ethanol has a memory? I could see nanobubbles and silicate chips forming in ethanol, but I haven't heard &mdash; doesn't mean it can't exist in authoritative sources &mdash; of clathrates with ethanol. There is no question of the existence of clathrates, merely that they would have a physiological effect and they are commonly produced by homeopathic preparations.
First, the word " most <u>biased</u> medical " is argumentative, does not fit the language of the lede, and is clearly advocacy.


Water (H<sub>2</sub>O) is among the simplest of molecules, so the idea that it can be affected makes more sense than with other molecules. Ethanol (C<sub>2</sub>H<sub>5</sub>OH) is a larger molecule, so it may be more stable in forming complexes.
The statement supporting homeopathy in the lede, even if the references were solid, belongs, stylistically, in a later section on the mechanisms of homeopathy. One reference is, as far as I can tell, from a Brazilian university with a site in, presumably, Portuguese, which I do not read. We generally don't use non-English references, especially when they are not clearly from peer-reviewed journals or otherwise reviewed sources.  


Water is a polar solvent; ethanol is considered both positive and nonpolar, depending on whether or not you are looking at its hydroxyl group. Are there reports of its being involved in clathrate formation?
The other reference is from Khuda-Bukhsh, whom, I believe, has been in the memory of water controversy, is a review of possible molecular mechanisms of action. On first glance, it's an interesting paper, but does not talk at all about efficacy &mdash; just how homeopathic remedies may work, if they work. It doesn't belong in the lede, although it's not unreasonable to use it as a reference in a later section.


If not, since there seems no question ethanol is used in homeopathic remedies, are clathrates eliminated? Since the Avogadro limit would still hold, is there a homeopathic assertion that ethanol has a memory?
Neither addition works where it is. The first is advocacy and non-neutral. --[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:45, 7 January 2010 (UTC)
:The use of "biased" is definitely adversarial. [[User:Chris Day|Chris Day]] 21:12, 7 January 2010 (UTC)
:With regard to the rebuttal (it works, and we know how), I am loath to see this article head down the direction of he says, she says tit for tat. [[User:Chris Day|Chris Day]] 21:21, 7 January 2010 (UTC)


Assuming the preparations with quartz (impure silicon dioxide) and lactose are still in use, how do they have memory, if the Avogadro question still applies?[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:32, 11 October 2008 (UTC)
::The whole article is full of oxymorons, containng both viewpoints, so I don't see anything wrong with what I've inserted, unless the critics' statement is also removed (about what scientists feel). I'm fine if the word <u>biased</u> is removed, if it seems adversarial. The Portuguese and French is only in the references section and shouldn't be a problem.—[[User:Ramanand Jhingade|Ramanand Jhingade]] 10:28, 8 January 2010 (UTC)


== Explanation of deletion text making statement not supported by available citation ==
:::Well, Ramanand, the general CZ, policy, especially in the Charter, is that articles don't equally present all views. They present the preponderance of the expert views, and, in this case, the experts are in health sciences; there isn't a unifying discipline among healing arts. Not all healing arts support homeopathy.


::::Everyone needs to [[CZ:Neutrality Policy|Neutrally]] present all views. [[User:D. Matt Innis|D. Matt Innis]] 02:31, 9 January 2010 (UTC)


While only the abstract is available without a subscription, <nowiki><ref>Eskinazi D (1999) Homeopathy re-revisited: Is homeopathy compatible With biomedical observations?  ''Arch Intern Med''  [http://archinte.ama-assn.org/cgi/content/extract/159/17/1981 159:1981-7 ]</ref></nowiki> only says,  
::The foreign language citations have been a problem in many other articles, not just here.  
<blockquote>Increasing numbers of medical consumers seem to seek out homeopathic treatment.</blockquote>


The next citation doesn't actually point to a specific article, but to a <s>BMJ</s> special article on homeopathy. http://www.sciencedirect.com/science/journal/14754916. '''Correction:''' that reference isn't the ''British Medical Journal'', but the former ''British Journal of Homeopathy'', now retitled ''Homeopathy''.[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 19:15, 11 October 2008 (UTC)
:I think you mean contradictions or rather or challenges, not oxymorons. An oxymoron would be a "heroically large dose of a homeopathic simillum." An oxymoron is a contradiction in terms.


Dana added the text, "There is body of evidence that suggests that homeopathic medicines are fully compatible with modern biomedical observations and scientific perspectives." '''fully''' is questionable on the face of it. Further, "suggests" is more of a qualified word than, say, "confirms". If the evidence confirms, say so. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 18:27, 11 October 2008 (UTC)
:Sorry, I'm in favor of removing both additions. You will need to face the reality that the article will not be as pro-homeopathy as you want, just as others wish it weren't here at all. It's a compromise. --[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 15:48, 8 January 2010 (UTC)


:Howard, you are welcome to delete the word "fully."  That said, please read this article; it is well-referenced and published in a high-impact journal. [[User:Dana Ullman|Dana Ullman]] 18:17, 12 October 2008 (UTC)
::I applaud, encourage and appreciate collaborative efforts to work toward improvements, but I think this lead still needs significant work to add any substantial improvement to the approved version's lead. [[User:D. Matt Innis|D. Matt Innis]] 02:28, 9 January 2010 (UTC)


== Scientific basis of homeopathy ==
:::I forgot to wish all of you a Happy (belated) New Year. The presently approved article's Lead isn't 'neutal' at the moment. It should either explain homeopathy plainly or if y'all want criticism in the Lead, it should contain both viewpoints. Where's Dana, by the way, in Germany again?—[[User:Ramanand Jhingade|Ramanand Jhingade]] 09:14, 9 January 2010 (UTC)


Let me assume I were a homeopath, trained as a biochemist, and an experienced writer (well, 2 of 3). If I were trying to convince people with conventional scientific training, I'd tend to go more with a smaller selection of articles of very well chosen articles'''There is one paper here that stands out from the others''', but it's not emphasized, yet it probably is stronger support than the rest put together, and doesn't apper to depend
:::: Happy New Year to you, too! Please let me know where you think the present Approved version lead (as opposed to the draft lead) is lacking and I'll be glad to take a lookDana approved the current lead, too, but I'm sure he'd take a look if we asked him.  [[User:D. Matt Innis|D. Matt Innis]] 15:00, 9 January 2010 (UTC)


First, I was reminded that even if "memory of water" was proven, that doesn't explain modes of action in remedies that use ethanol, quartz, or lactose, all mentioned.
:::::I'd posted a whole lot of links to homeopathic articles, late last year, but did not have the time to add it in the article. I was expecting someone here to do it, but no one did (not even Dana)! I already wrote what I wanted above, "It should either explain homeopathy plainly (without criticism in the very 1st sentence) or if y'all want criticism in the Lead, it should contain both viewpoints."—[[User:Ramanand Jhingade|Ramanand Jhingade]] 08:34, 12 January 2010 (UTC)


Second, simply to mention that homeopathic remedy preparation creates changes in water, but that these changes have no understood physiological relationship, it is getting into speculation inappropriate for an encyclopedia article. Examples:
::::::We certainly can't add every link ever written to this article.  This is the overview article in an encyclopedia type format and summarizes homeopathy pretty well, I think.  Again, don't confuse the lead in the Draft with the lead in the main [[Homeopathy]] article.  I agree the lead in the draft needs more work and is not an improvement in its current form. [[User:D. Matt Innis|D. Matt Innis]] 12:45, 12 January 2010 (UTC)


:<nowiki><ref>Rey L. Thermoluminescence of ultra-high dilutions of lithium
:::::::If nothing else, bibliographic links not directly related to the text belong on the bibliography page, preferably in articles. Also, in other articles, there is some selectivity. In some cases, reviews are more appropriate than small primary studies. In other cases, peer review and responsible publications are appropriate. In yet other cases, there is more leeway on publications but the reason needs to be explained.
chloride and sodium chloride, Physica (A) 2003; 323: 67–74.</ref></nowiki>


What physiological mechanism is affected by thermoluminescence?
:::::::It's not necessarily reasonable to assume someone else will edit and add articles with which they aren't familiar, or with which they might disagree.


:<nowiki><ref>Bell IR, Lewis DA, Brooks AJ, et al. Gas discharge visualisation
:::::::What principles of homeopathy are in not in the lead?  It should go without saying that homeopathists believe what they are doing, or the article wouldn't be here at all. Having a small number of dissenting comments from people who question hematology simply establish it isn't universally accepted, and the details and pros and cons should be in the article, but later. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 13:27, 12 January 2010 (UTC)
evaluation of ultramolecular doses of homeopathic medicines
under blinded, controlled conditions. J Altern Complement Med
2003; 9: 25–38.</ref></nowiki>


Nothing here identifies a cellular interaction, and solving memory of water doesn't solve the Avogadro problem in non-aqueous diluents.  
::::::::RE: provided references from Ramanand, [http://en.citizendium.org/wiki/Talk:Homeopathy/Archive_11#Long_time_no_see_.28post.29.21 this must be the list] and I do remember it, but it's mostly primary research.  They could be used for a more detailed article to support a specific claim where reviews aren't available, but to cite them here would result in too much detail for the general nature of this article. Primary research doesn't belong in a bibliography either.  I'm not sure that we have a subpage that would be appropriate for primary research, though it's an interesting idea for some other project, or way in the future for this one.  Otherwise, I'd think it would be a problem with [[CZ:Maintainability]]. There are other sites that do list all the research for each particular subject. [[User:D. Matt Innis|D. Matt Innis]] 14:51, 12 January 2010 (UTC)


:<nowiki><ref> Elia V, Niccoli M. Thermodynamics of extremely diluted aqueous
:::::::::This is one page ([[Homeopathy/Trials]]) that exists with a tabulated summary of some of the voluminous primary literature. I agree maintainability is an issue. I bet there are hundreds of articles like this and the main problem is reducing it to the most important articles in the field. If that could be done well it might make a good catalog. [[User:Chris Day|Chris Day]] 17:18, 12 January 2010 (UTC)
solutions. Ann N Y Acad Sci 1999; 879: 241–8. </ref> </nowiki>


Same as above.
:::::::::Matt, I made some time to read the entire (presently) approved article. I don't see any sentence saying there is evidence for homeopathy (the feg pdf document I've inserted in the present draft is accepted by 'mainstream' scientists as well). I object to the term 'placebo' in the lead (Edzard Ernst is known to be a ridiculed homeopathic baiter in the U.K.). I also object to the term 'fraud' in the Overview section<blockquote>They also are interested in whether positive results against expectation sometimes reflect manipulation of data or perhaps even fraud. </blockquote>. Like you said, can we edit the (presently) approved article?—[[User:Ramanand Jhingade|Ramanand Jhingade]] 17:34, 23 January 2010 (UTC)
:::::::::David (Ellis), can you please tell me what objections you have to the feg pdf document?—[[User:Ramanand Jhingade|Ramanand Jhingade]] 17:42, 23 January 2010 (UTC)


:<nowiki><ref>Linde K, Jonas WB, Melchart D, et al. Critical review and
(undent)
meta-analysis of serial agitated dilutions in experimental toxicology.
Placebo in the lead is perfectly appropriate; conventional medicine routinely accepts the placebo effect as a component of therapies.
Hum Exp Toxicol 1994; 13: 481–92.</ref> </nowiki>


Same as above.
Fraud is mentioned gently as a possibility by some observers, seemingly far more gently than some of the homeopathic claims of the danger of medicine. Sorry, it's not unbalanced.  Please do not go to "known" homeopathic baiters anywhere, else that you start having people bring in medical baiters from homeopathy. The problem with bait is that it often has a hook inside.


:<nowiki><ref>Belon P, Cumps J, Ennis M, et al. Histamine dilutions modulate
By edit the presently approved article, no, other than for typos, it's frozen. It is possible to edit the draft, and eventually to have the edited draft become the newly approved.  
basophil activation. Inflamm Res 2004; 53: 181–8.</ref> </nowiki>


The above paper is one you '''should''' use, and '''explain further'''. Modulated basophil response is something that would affect asthma. (addition: not having access to the paper itself, I assume histamine is the active homeopathic ingredient. Correct? Interesting, if so, in that histamine has to be extracted or synthesized; it's not a naturally occuring isolated compount. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 03:42, 13 October 2008 (UTC)
Again, what specific principles of homeopathy '''are not'' in the lede? --[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 18:03, 23 January 2010 (UTC)


:<nowiki><ref>Zausner C, Lassnig H, Endler PC, et al. Influence of a homoeopathically prepared thyroxine dilution on the metamorphosis of highland frogs – results of a multicenter
:Friends, it has been a while since I check-in here. I have not re-read most of the new draft, but I can tell you that I do not like the lede paragraph. It is simply not encyclopedic or impartial. Anyway, we only recently spent a lot of time approving the previous edition.  I suggest that we let it sit for 3-6 months or more before we re-do it. [[User:Dana Ullman|Dana Ullman]] 05:28, 1 February 2010 (UTC)
controlled trial. Perfusion (Nürnberg) 2002; 17: 268–76.
</ref> </nowiki> "that were different from the "control" effects of the water used for the dilutions. The work resulted in considerable controversy, and some other labs were unable to reproduce the reported effects."


Is this the sort of report that strengthens a case?[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 18:22, 12 October 2008 (UTC)
::Dana, I hope you can insert sentences that read something like, "there is scientific evidence for homeopathy", using the PDF for "Scientific framework of homeopathy: evidence-based homeopathy" available at http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewFile/286/354 wherever appropriate.—[[User:Ramanand Jhingade|Ramanand Jhingade]] 08:21, 2 March 2010 (UTC)


: I'm not clear on your point here, but let me simply say that skeptics of homeopathy insist that there is NO difference between the biological activity and clinical efficacy of a homeopathic medicine in comparison with a placebo.  All of the above studies that you cite prove otherwise.  I also want to clarify that the "active ingredient" in a homeopathic medicine is the entire substsance that is potentized, not any individual chemical within that substance but the whole thing.  Like I have said several times in the past, you will become an even better CZ editor when you understand the system of homeopathy, not just individual controlled trials.  [[User:Dana Ullman|Dana Ullman]] 23:55, 13 October 2008 (UTC)
=== British House of Commons Science and Technology Committee report ===
::'''Constabulary:''' The previous characterization of "making me a better editor" is patronizing and unprofessional. I have repeatedly objected to Dana's analyzing my motives, and also of being extremely patronizing.


:::It is rather disingenuous to say "I don't understand your point" and then go off about "skeptics" and placebos. I did not write one word about placebo. Let me rephrase: was histamine the substance added to water to produce the remedy? That is what I meant by "active ingredient".  Would you prefer "precursor". "Simillum"?  The authors did not title the article "the effects of histamine-treated water", but of diluted histamine. The abstract speaks of a preparation.
The committee commissioned by the British government has reassessed homeopathy as a treatment option under the national health service. It's enquiry sought written evidence and submissions from concerned parties (See [http://www.timeshighereducation.co.uk/story.asp?sectioncode=26&storycode=408852&c=1 News in brief: Homeopathic assessment] and [http://www.parliament.uk/parliamentary_committees/science_technology/s_t_pn05_091020.cfm Evidence check: Homeopathy]). Both sides of the debate were represented and presented written evidence to the committee. In addition there were oral presentations from the following individuals:


:::And, Dana, you don't seem to understand that my lack of interest in learning the depths of homeopathy is irrelevant to my editing this article. An effective encyclopedia article educates. It does not require going off and immersing oneself in the field to understand the nuances of the article. Please stop telling me to go off and study homeopathy, or making sarcastic observations about my "newfound passion" for homeopathy.  While I don't know if it can be done, I want to see this article stand on its own and give a coherent explanation. I want it to stop contradicting itself, and I want it to stop usurping and redefining well defined terms. I want non-authoritative testimonials and popularity contests gone.[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 02:39, 14 October 2008 (UTC)
*Mr Mike O'Brien QC MP, Minister for Health Services, Department of Health;
[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 02:39, 14 October 2008 (UTC)
*Professor David Harper CBE, Director General, Health Improvement and Protection, and Chief Scientist, Department of Health;
*Professor Kent Woods, Chief Executive, Medicines and Healthcare Products Regulatory Agency
*Professor Jayne Lawrence, Chief Scientific Adviser, Royal Pharmaceutical Society of Great Britain;
*Robert Wilson, Chairman, British Association of Homeopathic Manufacturers;
*Paul Bennett, Professional Standards Director, Boots;
*Tracey Brown, Managing Director, Sense About Science;
*Dr Ben Goldacre, Journalist.
*Dr Peter Fisher, Director of Research, Royal London Homeopathic Hospital;
*Professor Edzard Ernst, Director, Complementary Medicine Group, Peninsula Medical School;
*Dr James Thallon, Medical Director, NHS West Kent;
*Dr Robert Mathie, Research Development Adviser, British Homeopathic Association.


== Pinning down some terminology ==
A summary statement from the House of Commons Science and Technology Committee was released with the report in Feb 2010:
{{quote|... the NHS should cease funding homeopathy. It also concludes that the Medicines and Healthcare products Regulatory Agency (MHRA) should not allow homeopathic product labels to make medical claims without evidence of efficacy. As they are not medicines, homeopathic products should no longer be licensed by the MHRA.


From the article,  
The Committee concurred with the Government that the evidence base shows that homeopathy is not efficacious (that is, it does not work beyond the placebo effect) and that explanations for why homeopathy would work are scientifically implausible.


<blockquote>In homeopathic theory, every person has "life energy," sometimes called a "vital force," which today's homeopaths consider to include a person's [[immune system]]. </blockquote>
The Committee concluded - given that the existing scientific literature showed no good evidence of efficacy - that further clinical trials of homeopathy could not be justified.


Is the term "life energy" or "vital force", and can it be defined? Is it the same or different than "wisdom of the body"? Some of these terms are wikilinked to null articles, which suggests to me someone thinks they can be defined.
In the Committee’s view, homeopathy is a placebo treatment and the Government should have a policy on prescribing placebos. The Government is reluctant to address the appropriateness and ethics of prescribing placebos to patients, which usually relies on some degree of patient deception. Prescribing of placebos is not consistent with informed patient choice-which the Government claims is very important-as it means patients do not have all the information needed to make choice meaningful.


"Immune system", and there's really not one immune system, has a generally accepted meaning among any medical personnel that have studied current immunology. What do homeopaths mean by immune system? Is it wiser to use "vital force' (or your choice of terms) so there isn't an apparent redefinition.  The MeSH definition is "The body's defense mechanism against foreign organisms or substances and deviant native cells. It includes the humoral immune response and the cell-mediated response and consists of a complex of interrelated cellular, molecular, and genetic components." Since some of its parts act in opposition/regularizing o the other, "strengthening" just doesn't make much sense.
Beyond ethical issues and the integrity of the doctor-patient relationship, prescribing pure placebos is bad medicine. Their effect is unreliable and unpredictable and cannot form the sole basis of any treatment on the NHS. <br/>'''Source:''' UK Parliamentary Committee Science and Technology Committee - [http://www.parliament.uk/parliamentary_committees/science_technology/s_t_homeopathy_inquiry.cfm "Evidence Check 2: Homeopathy"]}}


The training of the homeopathic practitioner, MD, DO, RN, etc., shouldn't make much difference; any would receive similar training. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 21:22, 13 October 2008 (UTC)
From the full report the committee also stated:
{{quote|
We conclude that placebos should not be routinely prescribed on the NHS. The funding of homeopathic hospitals — hospitals that specialise in the administration of placebos — should not continue, and NHS doctors should not refer patients to homeopaths.<br/>'''Source:''' [http://www.publications.parliament.uk/pa/cm200910/cmselect/cmsctech/45/45.pdf Evidence Check 2: Homeopathy, Fourth Report of Session 2009–10], House of Commons Science and Technology Committee, 20 October 2009, parliament.uk}}


: Someone has changed what I previously wrote. Originally, I had written that a person's life force or vital force (they are synonymous), but I referred to it in today's language as similar to what we call a person's "immune and defense system."  Because our body's defenses are not just its immune responses, I recommend that we re-insert what was originally written. I did not write that homeopathic medicines "stimulate" the body's immune system; I had written that they seem to "augment" immune response because there is evidence that these medicines stimulate immune function and at other times they tonify an overly active immune system. A reference for this is:  http://ecam.oxfordjournals.org/cgi/content/abstract/3/1/13
In conclusion the chairman of the committee said:
[[User:Dana Ullman|Dana Ullman]] 00:04, 14 October 2008 (UTC)
{{quote|
This was a challenging inquiry which provoked strong reactions. We were seeking to determine whether the Government's policies on homeopathy are evidence based on current evidence. They are not.


::For vital force or life force, may I ask that one be picked, for the benefit of readers who do not know they are synomomous.
It sets an unfortunate precedent for the Department of Health to consider that the existence of a community which believes that homeopathy works is 'evidence' enough to continue spending public money on it. This also sends out a confused message, and has potentially harmful consequences. We await the Government's response to our report with interest.<br/>'''Source:''' UK Parliamentary Committee Science and Technology Committee - [http://www.parliament.uk/parliamentary_committees/science_technology/s_t_homeopathy_inquiry.cfm "Evidence Check 2: Homeopathy"]}}


::I would argue strongly against "immune and defense system", but have no objection to "defense system". Since "immune system" is a well-defined technical term in biomedical sciences, if that term is used, it is reasonable that it be used precisely, which, in part, means using it with that precision. "seems" to is not acceptable scientific language and immune system is a scientific term. An authoritative article in the field might use "seems" in an abstract, but I am confident that no quality journal would allow that unless there is hard statistical data, with quantitative values of trust/error, elsewhere.
: The Evidence Check definitely needs to be in the article. It has been hilarious watching the homeopaths squirming around trying to explain it away by butchering the quote from Cucherat's systematic review. It is like those reviews you see on movie posters where it says something like "Tremendous, Exciting (Evening Standard)" and then you go and look and see what the Evening Standard actually say and it is "A tremendous waste of time and money, has difficulty exciting all but the clinically insane". –[[User:Tom Morris|Tom Morris]] 15:12, 3 March 2010 (UTC)


::Indeed, what your cited article actually says, in the last sentences of its abstract, are "It is our hope that this review of literature unknown to most people will give an original and useful insight into the ‘state-of-the-art’ of homeopathy, without final conclusions ‘for’ or ‘against’ this modality. This kind of uncertainty may be difficult to accept, but is conceivably the most open-minded position now." That's a lot weaker than "seems to". I would appreciate that when you cite abstracts, you stay with the level of certainty they have, not spin it into greater support than is written.
:: For some reason, I couldn't access Citizendium yesterday at this time. Meanwhile, I got a reply from Dr Peter Fisher to my e-mail in which he says that the individual specific rules of Homeopathy were not followed in prescribing/administering the Homeopathic remedy, so I hope good sense prevails over the 'UK Parliamentary Committee Science and Technology Committee'.—[[User:Ramanand Jhingade|Ramanand Jhingade]] 13:43, 12 March 2010 (UTC)


::I have absolutely no idea what it may mean to "tonify" an immune systems. I could describe a number of mechanisms that modulate specific immune mechanisms, or, if they faily, result in immune disease, but that is inappropriate at this level and in this article. Now, I shall go back to the article and edit it so it does not give the impression of pre-empting precise terms. Incidentally, I have been adding articles that carry referenced definitions of immunological terms. Perhaps, if you want to use such terms, you also might contribute in that manner. So many proteins, so little time...[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 00:39, 14 October 2008 (UTC)
:::With regard to "the individual specific rules of Homeopathy were not followed in prescribing/administering the Homeopathic remedy" what is Peter Fisher referring to? How does that impact the report? [[User:Chris Day|Chris Day]] 16:25, 12 March 2010 (UTC)


== "Unsubstantianted and vague" ==
::::As I understand it, the individual specific rules of homeopathy mean that every patient is unique and the remedies appropriate for one will not be appropriate for another. Let's assume this is exactly correct. That would make classic randomized clinical trials, in which there is a standard treatment arm and a control arm, inappropriate, because there is no homeopathic standard.


Dana deleted my addition of a sentence "Not all homeopaths recognize the model of a disease being a disturbance  that needs to be corrected." He did not follow the practice of explaining a deletion on the talk page, which I have tried to do.
::::A very similar problem, however, applies to highly individualized [[pharmacogenomics|pharmacogenomic]] therapies: within a cohort of patients with, say, metastatic breast adenocarcinoma, the experimental hypothesis may be that a given treatment is applicable only to those patients with a specific BRCA gene coding. Panaceamycin is only expected to be effective in patients with that characteristic, and the others should get an aromatase inhibitor, the standard of care. Given there is a treatment, a placebo control is ethically unacceptable.  


I would observe that homeopaths in this article, and certainly in easily obtained references, repeatedly reject the concept of disease, especially as something that causes symptoms, and instead insist that the symptoms are merely the manifestation of the body's own healing.  Doing anything that is not focused on those symptoms gets away from the concept of ''simillium''.  
::::RCT's have been designed that still have statistical power, but are testing the diagnostic and treatment model, not panaceamycin.  The clinician selects the treatment and sends an order to the pharmacy, where the pharmacist opens the next blind assignment envelope. If the patient is assigned to the experimental arm, the IV drug unit sent back to the care unit has panaceamycin in it if the genomic model calls for it, and the control treatment if not. If the patient is assigned to control, she gets control. It is the decision to assign that is being tested, more than the drug itself.


So, Dana, how many references do you need? Give me a number. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 02:29, 14 October 2008 (UTC)
::::In like manner, homeopaths could prescribe a totally individualized remedy, but they would be blinded to whether or not the patient gets the remedy -- control could be placebo, or a medical treatment. With a sufficiently large sample, if the homeopathic model is correct, the patients receiving the remedy should do better.


:I think I would have deleted that one myself, Howard ;-) I'm not sure what it means. I think I know what you are trying to say, but that wasn't it. Keep trying.
::::It is not clear that homeopaths are willing to be tested in such a manner, which should obviate the argument about individualization not being permitted. --[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:05, 12 March 2010 (UTC)


:I don't see anything wrong with homeopaths entering the 21st century trying to explain what they do in modern termsI also don't see that we can take this article space to try to explain how the body defends itself, especially since this is extremely difficult to fathom, much less explainAs our previous reference suggests, we don't know the mechanism that makes homeopathy work, assuming it does, but that does not mean that it has no value, whatever that might beOur error is in trying to suggest that we know anything about how it works, or whether it works. I like the idea of succinctly describing "life force" or "vital force" as a centuries old metaphor for explaining everything we don't know about what makes us tick, and even that the "immune system" and our "body's defenses" are part of that, especially if this is what homeopaths tell their patientsHowever, we need to be sure that the reader knows that we don't know how it affects the immune system, or for that matter "vital force".  I think you are both working in that direction, so I don't see any need to drastically interfere with your progress other than a few clarifying or copy edits. 
:::::Brings me back to a question that I have never seen an answer to.  How can remedies be mass marketed and sold off the shelf at places like wal-mart and whole foods and be so effective (as claimed)? These remedies are either robust or need to be highly individualizedIf the latter, I don't see how how a mass market product will work.  If the former, then they have indeed being found wanting (no better than placebo). Their defense against accepting the failed results of clinical trials precludes claiming successes from the mass market productsWhich is it? [[User:Chris Day|Chris Day]] 19:15, 12 March 2010 (UTC)
:[[User:D. Matt Innis|D. Matt Innis]] 02:58, 15 October 2008 (UTC)


::The problem here Matt, is that some theorizing, skeptical, critics who have never tried homeopathy think they know more about homeopathy than homeopaths themselves.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 03:04, 15 October 2008 (UTC)
::::::A question, Chris, that I've asked myself. Let me respond indirectly.  One of the major mass-marketed products is [[Oscillococcinum]], about which I did write an article. What is the sound that is made by the creature from which the simillium is obtained? --[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 19:28, 12 March 2010 (UTC)


:::That's part the problem :-)  Though theorizing and skeptical are pretty much the definition of scientist. Criticism can be constructive if given and taken in the right way.  Homeopathy has it's place, as evidenced by the fact that it has a place.  We just need to explain it that way.  As professionals, we work every day taking care of our patients, but we don't really know if we are helping our patients better than other forms of therapy are working.  For this we need the research. [[User:D. Matt Innis|D. Matt Innis]] 03:33, 15 October 2008 (UTC)
:::::::Given that they are a £1.5bn industry we can expect to hear a lot of noise like that in the next few months. [[User:Chris Day|Chris Day]] 19:40, 12 March 2010 (UTC)


::You make a very good point, Matt, about the 21st century. I am impressed, in a way, about the amount of commentary up to 1905 or so, but then dropping radically. I don't dispute that Osler questioned the doses being given by physicians of the time; very few modern physicians will argue that there were very, very few effective drugs at the time Osler spoke well of homeopathic dosages. I would make the point, however, that just a little has been learned in 103 years, including the rejection of things that don't work, and the substitution of things that do. I'd like to find, for example, a contemporary equivalent, in homeopathy, to the continuous improvement of treatment of metastatic breast cancer in postmenopausal women. Offhand, in 20-30 years, I can think of at least 5 changes, all demonstrating better efficacy, to the standard treatment, from the 5-drug Cooper regimen to aromatase inhibitors. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 03:32, 15 October 2008 (UTC)
:::::::: Howard, you got it right - for example, Ipecacuanha can't be given where Antim. Tart is indicated. Chris, classical homeopaths don't accept 'over the counter'/'off the shelf' products because anything between 2 to 20 remedies are mixed in one 'combination' (Hahnemann used to call such homeopaths the 'mongrel sect'), but since it's popular, the classical homeopaths can't do much about it. In India, homeopathy is a half a Billion $ 'industry' - and that is only counting the medicines sold 'over the counter' and not what is spent on homeopathic doctors - so we're not gonna let people talk rubbish about it. It really works (See the 'feg' pdf document I've posted in the previous section)!—[[User:Ramanand Jhingade|Ramanand Jhingade]] 09:22, 13 March 2010 (UTC)
::Homeopathy was working then as well as now, so why change something if it's good?&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 03:36, 15 October 2008 (UTC)


:::Well, of course [[Abraham Flexner]] played a big role in that along with the [[AMA]].  Homeopaths were the majority practioners before the turn of the century.  The AMA started somewhere around 1845, right.  Somewhere in the late 1800's, they began to investigate the ingredients in [[nostrum]]s and homeopathic remedies. Homeopaths, still invoking the vital concepts of "life force", had not placed much emphasis on scientific evaluation, because they considered the active ingredients to be immaterial and thus, by definition, undetectable.  As most physicians of the times used homepathic remedies at least with some illnesses, they didn't question much.  Rockefellar/Carnegie and Flexnor forced things to change in 1906-1910 - effectively placing healthcare squarely in the hands of science and materialists.  Doctors virtually stopped practicing homeopathy.  Of course, then comes WWI, the flu epidemic, then penicillin, the great depression, vaccines, WWII, the polio outbreak, railroad insurance, federal funding of university research, etc... until the late 1960s (Vietnam) and the social unrest and distrust of authority (Nixon) - which included the AMA.  That is when interest in alternative medicine was renewed... but Medicine hadn't noticed until 1996, when the research showed that their patients were spending as much on alternative medicine as they were on primary care.  It's all very interesting. [[User:D. Matt Innis|D. Matt Innis]] 04:05, 15 October 2008 (UTC)
Ramanand, you didn't get right the essence of what I was saying: there are statistically powerful testing methods, which have been developed for biological therapies that indeed are individualized, which could answer the homeopathic objection to more traditional randomized clinical trials. I have not seen any evidence that homeopaths are willing to use such methods, but instead continue to insist on either statistically weak retrospective analyses or anecdotal/testimonial evidence. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 16:21, 13 March 2010 (UTC)


::::Matt, I'd hesitate to use U.S. healthcare economics as evidence for anything related to reality. As I've suggested before, I'd be very interested in seeing outcomes and spending in a situation where there are no economic incentives or disincentives to a form of therapy. The AMA, incidentally, has been declining for years; their membership is distinctly a minority, for all the complaints against it.  
:Howard, it is very simple: the homeopaths are perfectly happy to use clinical evidence when it shows that homeopathy works. But when it shows that it doesn't work, then the clinical trial methodology must be at fault! Heads I win, tails you lose. If clinical trials are unable to detect the effects of homeopathy, why is the British Homeopathic Association quote-mining Cucherat? What seems more likely: that homeopathy works but not to the point where the clinical trial can detect it, or homeopaths cynically misuse evidence to support their pre-ordained conclusions? It has been so amusing to watch: our politicians have seen that the <s>King</s> alternative therapist is actually nude. All the homeopaths have been able to do is spin, quote-mine and clutch at straws. –[[User:Tom Morris|Tom Morris]] 18:38, 13 March 2010 (UTC)


::::For-profit insurers do things that minimize their costs, but it is a complex situation involving short-term and long-term costs. If, however, there was substantial evidence of efficacy for homeopathic treatment, I'd suspect the insurers would be screaming for it to be tried before other methods. There is a lot of very interesting economic analysis that could be in this article.
::I suppose there isn't really anything to do about it until there's a new Editorial Council and a reevaluation of workgroups. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 19:04, 13 March 2010 (UTC)


::::It isn't just that the amount of medical knowledge is increasing, but the rate of acquisition is increasing. In the seventies, the number of citations in MEDLINE doubled about every 7 years. They are now doubling every 3-4 years, and it's a matter of tools and techniques of research as well as funding. Witness, for example, that the R&D budgets of most pharmaceutical companies is exceeded by their marketing budgets; the peer-reviewed articles keep coming. It appears that homeopathy has not especially changed in the last century or so, which is not the case for all forms of CAM. Some here suggest, apparently, that it was immaculately conceived, or the equivalent, and does not need to improve. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:19, 15 October 2008 (UTC)
:::The draft is open to rewrite and, while I can't speak for everyone, I'll be glad to look at anything that gets put in it. I agree with Russell. [[User:D. Matt Innis|D. Matt Innis]] 03:17, 14 March 2010 (UTC)


== The National Center for Homeopathy ==
::::Howard, there is a lot of research going on in Homeopathy. Dr.Peter Fisher heads a research group in London and Dr.Rastogi heads a research group in India. I will email them about your suggestion. Tom, please look at the 'feg' .pdf document I posted - it is good, solid evidence that Homeopathy works!—[[User:Ramanand Jhingade|Ramanand Jhingade]] 11:44, 14 March 2010 (UTC)


Dana, I believe the National Center for Homeopathy (web-site: www.nationalcenterforhomeopathy.org)needs to be mentioned in this article - I hope you can look into it.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 03:01, 15 October 2008 (UTC)
Friends...in due respect, anyone who takes this "report" seriously has an axe to grind or is simply under-informed.


== Preparation with other than water ==
Any rational person should and must be very suspicious of this "report." The MPs (Members of Parliament) who were a part of the Science and Technology Committee which voted for this anti-homeopathy report comprised of five members, with three members barely eking out their victory. Of the three votes, two members did not attend any of the investigational meetings, one of whom was such a new member of the committee that he wasn't even a member of the committee during the hearings, and the remaining "yes" vote was from Evan Harris, a medical doctor and devout antagonist to homeopathy. This report was not exactly a vote of and for the people.  This information alone should entirely discount this "report" as a kangeroo court report that deserves that round circular file.


The section entitled "Preparation of homeopathic remedies" still includes quartz and lactoseQuartz was removed in the lead. Should it be removed here? If both are to be removed, is it to be concluded that homeopathy no longer uses similliums that are insoluble in water?
The very limited number of people who represented homeopathy were primarily three peopleThe others were entirely antagonistic to homeopathy or simply uninformed about it (such as the rep from Boots).   


What about ethanol? For chemical as well as regulatory reasons, it is unlikely that 100% ethanol is used; given the formation of an [[azeotrope]] at approximately 95 percent, it's hard even to get 100% ethanol. Is ethanol used only for initial solutions, which are then diluted in water, a common enough chemical technique?
Despite the use and acceptance of homeopathy throughout the U.K., there is a very active group of skeptics, with significant Big Pharma funding, who work vigorously to attack this system of natural medicine. Even though there is a wide variety of serious and significant pressing issues in British medicine and science today, an active group of skeptics of homeopathy successfully resurrected in October, 2009, a House of Commons committee, called the Science and Technology Committee, with the intent to issue a report on homeopathy. A leading skeptics organization, Sense about Science, that has been pushing for the re-creation of this Committee is led by a former public relations professional who worked for a PR company that represents many Big Pharma companies. Of additional interest is the fact that other Directors of the Sense about Science organization are a mixture of former or present libertarians, Marxists, and Trotskyists who also, strangely enough, seem to advocate for the GMO industry (ironically, libertarians normally advocate for a "live and let live" philosophy, but in this instance, it seems that they prefer to take choice in medical treatment away from British consumers).


If a substantial amount of ethanol remains in subsequent dilutions, is there an assumption that it has a memory, or is ethanol simply a means of exposing the simillium to water?
Sense about Science is a registered UK charity despite being a political pressure group. As such they have to divulge their sources of income which they do on their website. Not surprisingly, much of this comes from named pharmaceutical manufacturers.


If I am using "simillium" incorrectly, please give me the correct term for that which is added to the solvent. I have been chastised for calling it an active ingredient; I would prefer to call is a solute that is dispersed in solution. "Remedy" is something I would prefer not to use, as the term makes assumptions. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 16:47, 15 October 2008 (UTC)
One of the investigators for the House of Commons Science Committee is a Liberal Democrat MP, Evan Harris. He has collaborated with Sense About Science on various projects, and he was also one of the skeptic demonstrators against the national pharmacy chain, Boots, which sells homeopathic medicines. This advocacy role does not make him an unprejudiced observer as is required for this type of investigation.


: I do not know where you are getting your information on homeopathy, and I am again concerned that you're wasting your and my time here. I urge to consider decreasing your questioning my actions UNLESS you have evidence that I've erred (heck, we all err).  I just don't understand how you can say or defend that homeopathic medicines are dispensed in quartz.  Nor do I understand why you want to create a hyper-technical lead to this article. The people who edit on CZ are supposedly experts.  I urge you to edit on your expertise and keep your questions to your expertise.  In the future, I will avoid answering your Talk points that stray, like this one above.
A report from this kangaroo court was issued recommending that the National Health Service stop funding for homeopathy and homeopathic doctors, despite the support for homeopathy and for consumer choice from Mike O'Brien, the country's present Health Minister. This report is only of an advisory nature, and because the Health Minister has already expressed his support for consumers' right to choose their own health care, it is uncertain what, if anything, will result of this report. What was most surprising about this report was that it verified that when people repeat a lie frequently enough, such as "there is no research on homeopathy," many people actually believe it, despite its transparent falsity.[[User:Dana Ullman|Dana Ullman]] 05:33, 7 May 2010 (UTC)


: To clarify, the word "simillimum" is the word that means:  the homeopathic medicine that is most similar to the overall symptoms of the sick person.  I do not want to see homeopathic lingo in the lead, nor do I want to see any hyper-technical information there.  [[User:Dana Ullman|Dana Ullman]] 22:01, 15 October 2008 (UTC)
== Sources ==


::Above you say that "''The people who edit on CZ are supposedly experts.''" This is not true. Anyone with an account can edit any article in CZ, in a similar way to wikipedia.  The difference is that you need to provide your name to get an account and there are some experts available to approve articles and adjudicate arguments over content ''if'' necessary. [[User:Chris Day|Chris Day]] 22:11, 15 October 2008 (UTC)
I'm surprised that this article does not reference or discuss Paul Starr's Pulitzer Prize and the Bancroft Prize winning book on the social transformation of American medicine. Any article that wishes to understand the difference between allopathy and homeopathy needs to understand that this debate has less to do with science or medicine and everything to do with politics as the British report makes clear. [[User:Russell D. Jones|Russell D. Jones]] 15:41, 2 March 2010 (UTC)


:::And may I add that contributors to CZ are not supposed to push any specific agenda or hobbyhorses of their own -- they are supposed to both write and edit with a scrupulous neutrality, which you are obviously not doing. [[User:Hayford Peirce|Hayford Peirce]] 22:56, 15 October 2008 (UTC)
:At one time, it was indeed appropriate to compare allopathy and homeopathy.  While some dictionary definitions still use allopathy as a synonym for conventional medicine, I find the modern usage to be more often by CAM practitioners, as that-which-we-do-not-do. (For the record, I happen to find some ''complementary'' medicine useful, or at least worthy of trial in non-critical situations.)


::::Where have I gotten quartz? From the lead of the [[homeopathy]] article itself. It was there when I first saw the article, and I had no reason to challenge it. If you don't want "homeopathic lingo", give me a term to use for the substance dissolved in water. When I said "active ingredient", there was homeopathic objection to that, because it was said the "entire preparation" is active. Will "solute" suit you, or is that term, from high school chemistry, "hypertechnical".
:As far as a "modern" comparison, however, I cannot do better than William Osler:
:<blockquote>A new school of practitioners has arisen which cares nothing for homeopathy and still less for so-called allopathy. It seeks to study, rationally and scientifically, the action of drugs, old and new."(Flexner report, page 162)</blockquote>


::::Please define what you mean by "hyper-technical". It's no more technical than in any health sciences article, and less so, than, say. [[complement]] or [[eosinophil]]. So far, I'm afraid I find that anything that is less than supportive of homeopathy is taken to task for some reason. Comments about wasting time get very close to unprofessional conduct, as do judgments on peoples' motivations.  
:Unquestionably, there was once a competition between something one could legitimately call allopathy, as a "doctrine of opposites", and homeopathy as a "doctrine of similars". Homeopaths often selectively quote Osler as saying that the homeopathic remedies were safer than most allopathic remedies of his era (i.e., late 19th-early 20th century). You'll note that there was insistence on keeping the 1905 quote from von Behring.


::::If you didn't like quartz in the introduction of the article, or in the body of the part on preparation, you have had weeks to remove it. I didn't put it there. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 23:50, 15 October 2008 (UTC)
:It ain't the 20th century any more, and conventional physicians don't prescribe based on opposites, nohow. Yes, there are political residues, but there's now a lot more in the way of evidence-based medicine...and protecting turf. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 19:37, 12 March 2010 (UTC)


I take exception to Hayford's statement above. Previously, there were four references in the lead to the skepticism or unproven or unaccepted nature of homeopathy, and this redundancy didn't make sense to me. There are many sentences that I have written in this article that have expressed some type of skepticism of homeopathy and will continue to do so when appropriate, but I will avoid doing so when it seems overdone or redundant. 
::My favorite quote from Paul Starr's book is:  “Because homeopathy was simultaneously philosophical and experimental, it seemed to many people to be more rather than less scientific than orthodox medicine.” [[User:Dana Ullman|Dana Ullman]] 05:37, 7 May 2010 (UTC)


Howard, my apologies if I inferred that you have placed the word "quartz" in the lead.  I simply saw you defending it and didn't consider it worth defending (because there is no basis of fact in it). 
== The memory of sugar ==


To clarify, homeopathic medicines are called THAT or "homeopathic remedies" or "homeopathic drugs."  Just as people refer to "home remedies" which does not mean that they are "scientifically proven" or not...but that they are used to remedy a problem.  The above reference to the word "solute" is too technical and seemingly not clear to the average reader. [[User:Dana Ullman|Dana Ullman]] 21:24, 16 October 2008 (UTC)
is being discussed [http://ff.im/gOS59 here] and provides a nice illustration of the topic. --[[User:Daniel Mietchen|Daniel Mietchen]] 21:56, 3 March 2010 (UTC)


:Note that quartz is still used elsewhere in the article. If it's wrong, take it out, but quarts and lactose do seem to be used with historic sourcing.
:I thought the "memory of sugar" tended to go either to the abdomen or buttocks, depending on genetics? :-)


:I'd expect a high school student to understand solute, but please pick two acceptable words. Let's assume water is the only solvent used. What general term do homeopaths used for the substance that is put into the water and shaken?  Since there is so much emphasis on shaking, clearly, there is an interaction between this unnamed thing and water. Surely there is a name for the thing, because until it is appropriately mixed, shaken, and diluted, it is not yet a remedy. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 03:02, 17 October 2008 (UTC)
:Seriously, the discussion at that link is what I'd suggest is an expectation. It is possible to be neutral, I think, and mention, in the lede, that homeopathy is not generally accepted. We still do not have a way of dealing with the situation where homeopathy supporters will support a lede that doesn't consider it reasonably credible. Of course, in no other workgroup do we have an equivalent to the health sciences/healing art splits. Should Religion be joined by Atheism?  Alternatively, is it possible to have a reasonable Atheism article in Religion? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 22:46, 3 March 2010 (UTC)


== "Synonymous with" and other items ==
::The problem just isn't there with religion and atheism. If you, say, are interested in philosophy of religion, you can get a degree in it regardless of whether you are an atheist or a theist (or something else entirely). I say this from experience - I have a BA in Philosophy, Religion and Ethics from a Catholic college but am an atheist. There are some - I guess the polite way of saying it is 'non-mainstream' - ways of getting a doctorate in religion. You could become a "Doctor of Scientology" (D.Scn) - I read today that Ron DeWolf - Hubbard's son - had been given one, and stated in court that he wasn't sure whether they gave him the Doctorate before or after he'd been given the Bachelors! Or you could get a phony Ph.D from a diploma mill - as quite a lot of the creationists have. The problem with Healing Arts is that you can quite feasibly become a Healing Arts editor with a degree from a non-mainstream parallel academic institution. When mainstream academia isn't bending over backwards to certify degrees in quackery (as two universities in Britain shamefully have), the quacks create their own academic institutions.


I deleted this: "is synonymous with what people today refer to be a patient's over defense system." Since most people today do not use any such term as "life force"--even I know that is taken as a long-discarded, antiquated notion--it certainly is not "synonymous with what people today refer to" as the body's defense system. This is simply to say that most people do not equate it with ''anything'' that they believe exists, because they think a "life force" ''doesn't'' exist. If I am mistaken, I'd like to see some explanation. Also, "a patient's over defense system" doesn't make sense to me. --[[User:Larry Sanger|Larry Sanger]] 00:39, 16 October 2008 (UTC)
::"Dr" Gillian McKeith "PhD" has a degree from a place called Clayton College of Natural Health in Birmingham, Alabama. Said college is not accredited by any accrediting body recognized by the Department of Education, and a number of states in the U.S. list it as unaccredited on their websites for student loans (etc.). This does not stop McKeith claiming to have a PhD on her website, nor did it stop Channel 4 television or her publisher from touting this to promote her books and TV programme. She also likes to mention how she is a member of the American Association of Nutritional Consultants. You too can be a member of the American Association of Nutritional Consultants if you send them $60! McKeith has pushed notorious nonsense like the idea that green vegetables are good for you because the green shows they have chlorophyll (true), and the chlorophyll will oxidate your blood (how? Human beings are not plants. They tend to get their oxygen through respiration rather than photosynthesis. And even if they were getting their oxygen through photosynthesis, even your local tanning salon lamps aren't quite powerful enough to penetrate your small intestines).


By the way, on the above point, I'm very open to restating the point so that it makes a claim about what all or some ''homeopaths'' believe.  If ''homeopaths'' use the phrase "life force" (or whatever), and if ''they'' equate that with the the body's "immune and defense system," grand--say so.  Just don't say (or imply) that this is an equation that ''physicians'' would make, because (I gather) the vast majority of them would scoff at the notion of "life force," which went out of style along with the vitalism that it implies. --[[User:Larry Sanger|Larry Sanger]] 01:37, 16 October 2008 (UTC)
::Another graduate of the Clayton College of Natural Health is cancer quack Hulda Clark who sells a whole variety of magic 'zapping' toys that make funny noises and shine lights and do little more to cure cancer than extract money from punters - I mean, cancer sufferers.


I also deleted this:
::Take any philosopher of religion or even most theologians - they'll certainly be able to say something useful on an article about atheism in the Religion WG. Same for the non-believers within the same fields. The problem with Healing Arts is it lets people with completely bonkers views about reality approve articles on their favourite pseudoscience. If the claims of the homeopaths were true (and, blimey, even our politicians can tell what a big pile of nothing the evidence of two hundred years of homeopathy has amounted to), then most of the articles in the Biology and Chemistry workgroup need rewriting.


:Because of their "respect for the wisdom of the body," homeopaths do not try to inhibit symptoms or suppress disease. The extremely small and specially prepared doses of remedies that homeopaths use are chosen for what they consider to be the unique ability of remedies to mimic the body's own defenses and initiate the healing process.
::I'll repeat myself again: we need to fix the Healing Arts bug. It is nothing more than a bug. It is a bug that is bringing down the great work done by other WGs. It says to anyone who has spent years of their life working on getting a PhD in physics or literature or psychology or whatever that you can get a fake degree from a non-accredited university and also be considered an expert on the same level. How can I, in good conscience, tell the experts in my field to contribute given this significant vulnerability in the Editorship system? –[[User:Tom Morris|Tom Morris]] 01:21, 4 March 2010 (UTC)


This, the first sentence in particular, does not make sense in context.  The very ''word'' "remedy" implies that homeopaths are trying to inhibit symptoms or "suppress" (I assume this means ''cure?'') disease. Is there supposed to be a difference between "suppressing disease" and "initiating the healing process"? If so, the article should explain that explicitly and then make the point in light of that distinction.
:::Religion seemed the obvious parallel, but we could, I suppose, have an Absolute Pacifism workgroup with Military -- not that quite a few professional soldiers don't hate war. Why can Engineering debunk a hoax theory but Health Sciences cannot? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 02:15, 4 March 2010 (UTC)


Also, what any of this has to do with something called "the wisdom of the body" is completely cryptic to meThat, too, needs to be explained in advance. --[[User:Larry Sanger|Larry Sanger]] 00:44, 16 October 2008 (UTC)
::::Howard, you're one of the eight CharteristsAre you a loud and strong voice therein trying to *remove* Healing Arts as a Workgroup, so that some of this nonsense could then be addressed in the future in a rational way? [[User:Hayford Peirce|Hayford Peirce]] 02:49, 4 March 2010 (UTC)


This is very confusing and seems overstated: "Some [[randomized controlled trial]]s that have tested the efficacy of all forms of homeopathic medicines have reported positive results..."  This sounds like there were several trials that ''each'' tested ''every'' homeopathic "remedy," and secured positive results for ''every'' remedy thus tested.  That surely can't be correct; and "positive results" is vague, anyway.  I've reworded it to mean what I believe the author meant. --[[User:Larry Sanger|Larry Sanger]] 00:54, 16 October 2008 (UTC)
:::::Compromise in the Charter Committee, I believe, means that the Workgroup and some other details will be passed, without detailed guidance, to the Editorial Council. Personally, I am urging the draft to go to discussion and markup, so we can proceed to the next steps after ratification. While this is an especially galling problem, there are less egregious workgroup structure problems that also need addressing and can't happen at the Charter level. --[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 03:21, 4 March 2010 (UTC)


:Larry, it is always a pleasure to have you come visit and to give your input.  To clarify, the words "life force" or "vital force" are homeopathic lingo for what most people today refer to as a person's "overall" defenses (I mis-typed previously and simply used the confusing word "over"). As such, it does make sense. And yes, homeopaths have a GREAT respect for the wisdom of the body...and for symptoms.  Thus, because the correct homeopathic medicine is one that will "mimic" the person's symptoms and help the body's defenses. This should not be cryptic. 
::::Even with Pacifism and the Military, there is an implicit understanding that most of the facts are the same. The Pacifist will agree with the General that the U.S. dropped the bomb on Hiroshima or that Nelson died in 1805. They have different opinions, but they do not care out their own ''facts'' in quite the same way as the Healing Arts gang. –[[User:Tom Morris|Tom Morris]] 07:32, 4 March 2010 (UTC)


:Larry's last comment is a good one.  I believe that we should delete "all forms of" and replace it with "select". [[User:Dana Ullman|Dana Ullman]] 03:17, 16 October 2008 (UTC)
:::::No, the analogy may hold. There are those that will insist that any enemy can be defeated through passive resistance and good thoughts, just as some of the healing arts believe that it is utterly wrong to immunize against an infectious organism or use an antibiotic against one. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 07:43, 4 March 2010 (UTC)


==Text reverts on 12 October...ongoing==
::::::Tom mentions non-mainstream ways of getting doctorates in religion. In fact the Archbishop of Canterbury still has the legal power to award them, which might explain why Church of England bishops always seem to be Dr. [[User:Peter Jackson|Peter Jackson]] 14:29, 12 March 2010 (UTC)
Ramanand, I restored changes made by both Hayford and myself. Let me try to explain.


:"<s>because homeopathic remedy selection may take time</s>; homeopathic remedies may be used after an asthmatic episode <s>to optimize the immune system and</s> prevent recurrences."
==How well does it work?==


Of course homeopathic remedy selection takes time; most non-emergency selection of medical drugs take time. Even in an acute asthmatic attack, it may take corticosteroids, even intravenously, 8 hours to have an appreciable effect. Saying it may take time to select long-term drugs simply adds words without adding information
We use double-blind studies to tell how well a particular medicine works. The person handout out the medicine does not know whether it's a "real medicine" just a sugar pill. In the case of pain relievers, the potency of an [[analgesic]] is rated in terms of how much more effective it is than a [[placebo]].


As far as "optimize the immune system", that has no meaning in the general scientific usage of "immune system". Why is it wrong to remove those words and leave "prevent recurrences", which is presumably the objective?
If I recall correctly, as much as 75% to 90% of the effective pain relief you get from the pills comes from the placebo effect: you take your aspirin or ibuprofen or (without knowing it) your sugar pill, and your headache starts going away within an hour no matter what. The real stuff is only slightly better.


If you are using "immune system" in a special homeopathic way, such as the way it has been suggested as a synonym for "vital force", say so. Otherwise, and this is probably not the place in the article, describe exactly what happens in the immune system, as the term is generally accepted. Mast cell desensitization? Neutralization or movement of immunoglobulins? Causing the inflammatory cells, such as leukocytes, to move out of the inflamed area?  
Given all that, how would we design a study to compare homeopathic treatment with conventional treatment? Is it possible to conduct a blind study, if the way the healer deals with the patient is a key ingredient of the therapeutic effect?


''Please'' don't take well-defined medical terms and give them new meanings, or use oversimplifications. Doing so breaks down any hope of communication between conventional and homeopathic participants here. Truly, I would not object if you had said "vital force" rather than "immune system". I don't know what a vital force is and whether it exists, but I am quite willing to accept that it is meaningful to homeopaths, and saying a remedy increases it does not conflict with medical terminology. Without insisting on a definition of vital force, if it were substituted for immune system in several places, I think the article would be more readable for all disciplines. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:17, 12 October 2008 (UTC)
For that matter, how can we compare Freudian [[psychoanalysis]] to Berne's [[transactional analysis]] or modern [[rational-emotive therapy]] or to a frank chat with a trusted friend or mentor (like Father O'Malley down at the local Catholic church)?


* I daresay one result of a careful attempt to measure outcomes could be that "bedside manner" is much more important than we've allowed ourselves to realize.


Quite a few reverts later.  The inclusion of "''[http://en.citizendium.org/wiki?title=Homeopathy&diff=100397421&oldid=100397413 because homeopathic remedy selection may take time]''" has been removed by Howard, Gareth and myself. An explanaition for why this is a critical sentence other than "this is how I treat myself" would be useful to move us forward. [[User:Chris Day|Chris Day]] 14:03, 15 October 2008 (UTC)
But I ask again, how do we study and quantify it? --[[User:Ed Poor|Ed Poor]] 02:04, 28 March 2010 (UTC)


:[http://en.citizendium.org/wiki?title=Homeopathy&diff=next&oldid=100398606 Just got reverted again], is "''I use it in acute attacks also-most homeopaths do; justify deletion (if you do) on the Talk Page ''" a convincing explanation? One that convinces Gareth and Howard? Is CZ comfortable "''[http://en.citizendium.org/wiki?title=Homeopathy&diff=100396567&oldid=100396566 messing with anaphylactic shock]''"? I thought Gareth made a reasonable point, not to mention the addition [http://en.citizendium.org/wiki?title=Homeopathy&diff=100396837&oldid=100396835 seems redundant with the sentence that follows]. Ramanand seems to imply that remedy selection does not take much time since he seems to be describing the use of homeopathy to control anaphylactic shock/acute attacks of ashma. I saw that Ramanand reduced the typical time for consultation with a homeopath from [http://en.citizendium.org/wiki?title=Homeopathy&diff=100398615&oldid=100398612 one hour to fifteen minutes], I assume with this scenario of "''acute attacks''" in mind (since it was the edit right after his revert). How do we know this is not an exaggeration or is there no consultation with "acute attacks" (even 15 minutes sounds on the long side here)? And if this remedy for "acute attacks" works so well, have any trials been done to prove to the skeptics that homeopathy is effective, at least for this type of case? This remedy would seem to be a perfect candidate for a double blind trial since individualisation appears not to be required in these cases and alleviation of the attacks should be easy to quantify. [[User:Chris Day|Chris Day]] 04:14, 16 October 2008 (UTC)
::If one were to review the entire body of experiments that Thomas Edison conducted on electricity, one would have to say that the vast majority of his experiments were failures...and one might fall into a trap by saying that he was a failure. Of course, we KNOW that this is not true.  Just because some studies have shown that homeopathic medicines don't work, there is a greater body of research to show that it does.  The trick is to know WHEN homeopathic medicines work...and when they don't.


::Part of the problem is that the severity of the attack is not clear. Is it, as you suggest, anaphylactic shock? Status asthmaticus? Things where it's a minute-by-minute call on whether to intubate, because laryngeal edema is one possibility? Do you have a rapid sequence intubation kit open and ready? Are arterial blood gases available? Even for a relatively mild but urgent case, that patient needs pulse oximetry, O<sub>2</sub> by nasal cannula and by more intrusive means if the SpO<sub>2</sub> drops. Nebulized albuterol,probably with intermittent ipratropium bromide, is almost certainly appropriate, while establishing IV access for epinephrine (unless it's intratracheal). Again assuming a serious event, a loading dose of methylpredisolone should be going on board. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:34, 16 October 2008 (UTC)
:: If anyone here wants to review a body of homeopathic research on a specific group of diseases (respiratory allergies) that have primarily been published in high impact conventional journals, such as the Lancet and the BMJ, you might consider reading this review of research I co-authored in a peer-review journal:  http://www.ncbi.nlm.nih.gov/pubmed/20359268 -- you can read the entire article online at:  www.altmedrev.com (It is in the Spring, 2010, issue, article #6). [[User:Dana Ullman|Dana Ullman]] 05:43, 7 May 2010 (UTC)


:::Gareth was the one that brought up anaphylactic shock, ramanand uses the phrase acute attacks.  You tell me if they are the same? Either way, if homeopathic remedies can alleviate acute attacks in minutes, I'm impressed. That's definitely quantifiable and publishable. [[User:Chris Day|Chris Day]] 04:42, 16 October 2008 (UTC)
== Unsupported assertions ==


::::I've been verifying this with a reasonably current Lange emergency medicine text, and, while there are similarities between anaphylactic shock and the most severe form of exacerbation of asthma, there are differences.
The current text has "Even in Europe, homeopathy is practiced by many conventional physicians, including 30-40% of French doctors and 20% of German doctors." and in the next paragraph "Some medical doctors, particularly in Germany, France, and several other European countries prescribe homeopathic medicines for wide variety of both self-limiting conditions and serious diseases with a high rate of patient satisfaction." There are no supporting citations.


::::In both, you want tight monitoring of the airway, but laryngeal edema is far more a threat in anaphylactic shock than status asthmaticus. The tendency to secure the airway by intubation is greater in anaphylaxis, because with sufficient edema, you may not be able to intubate -- you may have to do cricothryotomy or something more invasive. Epinephrine is the first-line drug for analphylaxis, with antihistamines (H<sub>1</sub> and H<sub>2</sub> both). and beta-adrenergic agonists as backup drugs; in severe asthma, beta-adrenergic agonists are the first-line, supplemented with anticholinergics. Both call for parenteral corticosteroids, but those take hours to take effect.
This is obviously redundant; we need ''at most'' one of these statements. However, neither strikes me as believable without support, so I am inclined to delete both. Anyone care to comment before I edit? [[User:Sandy Harris|Sandy Harris]] 15:29, 26 June 2010 (UTC)


::::On occasion, my ex-wife managed both. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:56, 16 October 2008 (UTC)
:Your point about unsupported assertions has come up before, and the current text, in my opinion, is significantly misleading. "homeopathy is practiced by many conventional physicians" does not, as much as some may want it to do so, imply that conventional positions endorse all of homeopathy. By definition, if they are conventional physicians, they are ''not'' practicing homeopathy as alternative medicine, but are using some complementary techniques from homeopathy. When I was last in my internist's office, I banged my shoulder against a piece of equipment. He rubbed it a bit. Does that mean he practices massage therapy?


::::There is some, 'individualization' involved even in acute attacks (of Bronchitis) - & no, I'm not talking of anaphylactic shocks. I did mention some remedies earlier (like Ars.Alb., Nat.Sulph & Ipecac), but it's difficult to explain all that to non-homeopaths, so I haven't included it in the article.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 03:11, 17 October 2008 (UTC)
:"Patient satisfaction" is a purely subjective assessment and is in no way evidence of efficacy. I could take the sentence starting "Some medical doctors..." and substitute "chemically pure water that has not been exposed to a simillium" and demonstrate high patient satisfaction.  


:::::Why is it so difficult to explain? I can give a mechanism of action for most pharmacologic drugs, or at least a reasonable approach to one? Perhaps the homeopathic model that there are no causes and effects are making it hard to explain. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:56, 16 October 2008 (UTC)
:I agree with deleting both. Even if citations are offered, they must be of a quality that indicates that homeopathic methods are a significant part of the practice of these physicians and they are not using it with the intent of creating placebo effects. --[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:05, 26 June 2010 (UTC)


:: It is a fact that at universities in Germany and Austria there are chairs and lectures on homeopathy (in Vienna also at the veterinary university). There are doctors who practice both. --[[User:Peter Schmitt|Peter Schmitt]] 23:10, 26 June 2010 (UTC)


:::::In any event, if it cannot be explained, and can only be taken on faith, it belongs in a CZ article in much the form "Creationists believe that all forms were created by the deity and there has never been evolution." Try that.  "Remedies", as opposed to non-homeopathic-lingo "symptoms", do not explain anything.
::: I have no problem if the two sentences ar combined. I think we've gone over this several times on the talk pages.  As Peter points out, there are obviously well established 'conventional' medical professionals that use homeopathy for treatment of medical conditions.  This is pretty much common knowledge at this point, so I don't see the need for citing a source for the mere fact that some medical physicians use homeopathy in their practicesHowever, when we add specific numbers such as 30-40%, it does seem to beg for a reference.  It shouldn't be hard to find such a reference if it is out there.  Otherwise, removing the numbers and just stating the fact shouldn't be a problem.


::::::Please do not tell me I'd understand if I tried it -- oh, and I happen to consider "skeptic" a compliment, so if you are trying to intimidate me with that, it's a waste of time. [[User:Howard C. Berkowitz|Howard C. Berkowitz]]04:37, 17 October 2008 (UTC)
::: I don't think we will be able to find any scientific sources that conclude that they use it only on undereducated healthy people as a placebo. In fact, I think the opposite is more likely the case. [[User:D. Matt Innis|D. Matt Innis]] 01:22, 29 June 2010 (UTC)


== Reality (pardon the expression) check? ==
Would someone who has access care to correct the glaring English mistake in the first paragraph of this approved article? [[User:Ro Thorpe|Ro Thorpe]] 00:16, 2 July 2010 (UTC)


It annoys me that I can't find a cherished book in my medical library, a 1934 volume entitled ''Modern Office and General Practice''. I cherish it because I have never seen, collected in one medical publications, as many things that are useless or actively dangerous. Glancing around, the first medical book that greets my eyes (the medical shelves are in another room) is a 1985 text on immunology, growing dated.
:I'm sorry, Ro, I must have a blind spot that is preventing me from seeing this glaring error. Could you be so kind as to point it out? [[User:D. Matt Innis|D. Matt Innis]] 01:42, 2 July 2010 (UTC)


May I ask why there is so much emphasis on what Osler and Hahnemann said about physicians I will cheerly stipulate were clueless?  Would it not be more to the point to find current and respected physicians taking current therapies to such task--perhaps things that have a reasonable base in molecular pharmacology, such as substance P transmission in chronic pain, or in insulin receptor insensitivity and the bleeding-edge work with incretin analogues, with immunomodulators, with any number of things?  Where, in homeopathy, are the hotly debated discussions on what some large-scale randomized controlled trials really mean in current therapy?
::Oh, so go ahead and shoot me!  I found it (after reading your request for Hayford to repair it :) [[User:D. Matt Innis|D. Matt Innis]] 01:46, 2 July 2010 (UTC)


(cues up Rocky Horror soundtrack) Let's all do the time warp again[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 23:03, 16 October 2008 (UTC)
:::Bang, bang - but you've removed it! Many thanks! [[User:Ro Thorpe|Ro Thorpe]] 12:16, 2 July 2010 (UTC)


== Strengthening the natural healing processes of the body ==
I provide many solid references to the use of homeopathic medicines by physicians in Europe in an article I wrote at:  http://www.huffingtonpost.com/dana-ullman/homeopathic-medicine-euro_b_402490.html  (It is NOT my intent for anyone to reference this article in OUR article at this website.  Instead, we can use many of the references provided.  This article also has many references throughout the article showing that people who use homeopathic medicines tend to have more education than those who don't.) 


Please reread Larry's comments. If you want to write "homeopaths believe they are strengthening the natural healing powers of the body", that is a perfectly acceptable statement of homeopathic belief. As soon as you make it a flat statement that they '''are''' strengthening the natural healing powers of the body, you throw the subject back open to challenge.
I urge us to be very careful in significant changing this article because a lot of time and thought went into it previously. [[User:Dana Ullman|Dana Ullman]] 18:05, 14 July 2010 (UTC)


That challenge, as long as you state it as more general than homeopathic theory, means that you have to define those healing powers and how the remedies affect them, or be subject to having it removed. Don't believe me; reread the Editor in Chief as to vitalism. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:43, 17 October 2008 (UTC)
== Review by a sceptical layman (i.e. me) ==


:Life force is an obsolete term even among homeopaths (we use the term, 'vital force' in the classrooms), but the word, 'theory', which you've put there, is fine with me.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 16:42, 17 October 2008 (UTC)
I'm reviewing the draft. Here is a rough summary of my changes and concerns:


::OK. I hope this is noncontroversial. I will change all occurrences, other than in direct and attributed quotes, of "life force" to "vital force". I will also reword the occurences of "natural healing powers of the body", or words to that effect, so it is clear the reference is to vital force. Is "Homeopaths believe they are strengthening natural healing processes, which they define as "vital force"," OK?
* I rewrote the paragraph in the lede section about the "long safety record". The reason homeopathy has a long safety record is the very same reason that not travelling has a long safety record: if something is inert and chemically indistinguishable from the delivery mechanism, it will be safe. Safety and efficacy is a balancing act. The reason homeopathy is safe is precisely because it isn't efficacious.


::I am not suggesting whether there is or is not a vital force, or trying to define it. That definition should come from homeopaths, as clearly as possible. What I am trying to do is make it clear when homeopathic versus medical models are being used to discuss a point. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:36, 17 October 2008 (UTC)
* I'm not wild about long, windy footnotes about Romanization. I've thus split off the Romanization note about the word "[[qi]]" on to a separate page.


== Trials in humans: editorial questions ==
* The section that is disputed about the number of practitioners in France and Germany is ''in the wrong place''. The way in which homeopathy is prescribed or accessed doesn't seem to be to be a principle of homeopathy - homeopathy is homepathy whether it is prescribed by a homeopath or bought over the counter. I've thus moved it into the section which used to be titled "Professional homeopaths: who are they?" which I have retitled "Homeopathy in practice". This section seems to be the place to discuss provision, prescription, education, regulation and the like.


Under "Trials in humans", there are nine conditions mentioned in the introductory paragraphy, but ten appear in the list. Should the text say ten?
* The paragraph starting "Homeopathic remedies can be prescribed by professional homeopaths" seems to be a tricky one. Depending on the country and the regulatory regime, homeopathy can be prescribed by a wide variety of people. Sadly (in my opinion), in Britain, quacks of all sorts can have their merry way with the public. Pretty much anyone can set themselves up as an alternative practitioner, so long as they don't make their claims too specific. But in other countries, this varies. It seems the important distinction that needs to be made is that homeopathy - unlike, for want of a better description, ''real'' medicine - can be prescribed by anyone.


I also split "allergies" and "upper respiratory infections", since seasonal allergic rhinitis appears in the table. The closest [[MEDLINE]]/[[MeSH]] heading to the latter is "Respiratory Tract Infections". Is that an acceptable replacement? What part of the body do homeopaths consider falling into that category?
* The rest of the section on "A typical homeopathic visit" seems to have some glaring problems. The homeopath is supposed to have EMT training in order to be "adequately trained"? (Heh. Surely, if heart attacks are the problem, what you need to do is to dilute high-fructose corn syrup into non-existence and it'll clear right up? I thought they believed in the law of similars. What's a defibrilator doing in the homeopath's office?) But anyway, this adequate training is according to ''who''? According to government regulations? According to the homeopathic groups? According to us? According to some third-party regulator like the [http://www.cnhc.org.uk/pages/index.cfm CNHC]?


My guess is [[pharyngitis]] and [[bronchitis]]; [[sinusitis]] and [[rhinitis]] have their own lines. Anything else? Pneumonia strictly limited without lower lung involvement? Infection-related [[bronchiectasis]]? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:59, 17 October 2008 (UTC)
* The article describes "classical homeopathy" at length, but I haven't seen any discussion of what the alternatives are to classical.


== Misplaced text ==
* There is a lot of repetition of parts of the article. The 'Principles' section is repeated in the section on 'The claims for homeopathy'.


This was in the section on vaccinations, but has no obvious connection to the heading.
* No criticism seems to be made of the "treating the whole person" idea. I'm not even sure that this is a desirable thing. If I break my arm, I want my arm fixed, not someone to waffle about my "disturbance in the overall homeostasis of the overall being". In fact, when I broke my arm as a child, I'm very glad that I had access to a surgeon to fix it. This kind of rhetoric seems to be just an evasion tactic - if the studies don't show that homeopathy actually fixes anything (and, well, it wasn't going to put the bones in my elbow back together), then they can justify this kind of thing by pointing out that the person feels vaguely better in some holistic sense.
<blockquote> Second, a homeopathic remedy is generally prescribed in a highly individualized fashion, not simply based on a person's conventional medical diagnosis, but based on the unique syndrome of symptoms that the person experiences. </blockquote>


It may go into the section on the examination, but it is quite misinformed to say that a physician will prescribe only on diagnosis. Many other factors are involved, beginning with the situation where the patient has more than one diagnosis (i.e., [[comorbidity]]) or is taking additional medications. In both these areas, one drug might be best for the comorbid conditions even though it might not be the first choice for either in isolation. Drugs may also have synergistic or antagonistic interactions with other drugs prescribed for other reasons.
* The paragraph about corticosteroids seems to be totally out of place. Oh, it sort of makes sense - it is a follow on from the last paragraph about homeopathy and asthma.


If a patient reports difficulty in falling asleep, although the chief complaint is headache, a wise prescriber might choose a preventive, sedating drug to be taken at bedtime, rather than one taken several times daily that also prevents migraine. Any number of factors including age, sex, pregnancy status, weight, difficulty in swallowing, impaired metabolism, use of tobacco or alcohol, activity level, and many other factors go into a thoughtful prescribing decision. The entire discipline of pharmacogenetics can make one drug appropriate and another drug inappropriate for a patient based on the presence or absence of certain genes.  
I've got a more radical suggestion. This article obviously needs a fairly ground-up rewrite. Here's what I reckon we should do. The current article seems to have been put together in a rather piecemeal way. Instead, I think the best way is to see if we can come together and work out a list of the fundamental questions that a good article on homeopathy should answer - then build a simple structure around those questions, and fill them in. We may be able to repurpose some of the text from the existing article.


Incidentally, one of my professional areas is the development of decision support systems to guide prescribers. In a seemingly routine matter such as prescribing the first drug for mildly elevated essential hypertension, there are at least four distinct classes from which the drug could be chosen, and, in addition, choices within classes. While essential hypertension has a single International Classification of Diseases code, there can be perfectly sound reasons to start one patient on a thiazide, another patient on an ACE inhibitor, and another on a beta-adrenergic antagonist.
I'd suggest the following list of questions:


It is agreed that homeopaths are expert in what they do in the practice of homeopathy; it does not follow that they are expert in the practice of medicine, or vice versa.[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 00:13, 18 October 2008 (UTC)
# What is homeopathy?
# Is there any known mechanism for homeopathy?
# Is homeopathy clinically effective?
# What are the main issues of contention regarding homeopathy?
# Why have there been campaigns against homeopathy like the 10:23 campaign?
# What is the history of homeopathy? Who is Samuel Hahnemann?
# How is homeopathic care provisioned and regulated in different countries?


:Good, so I hope you keep off homeopathic terms like vital force. I was just reading Hahnemann's, 'Organon of medicine' - he used the term, 'vis medicatrix naturae' for the natural healing processes; while vital force was much more than that. I'll try to describe (there is no fixed definition) vital force better in some time.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 01:23, 18 October 2008 (UTC)
Before formulating a structure for any potential rewrite, I'm interested in seeing if anyone has any other questions that they'd want to add. [[User:Tom Morris|Tom Morris]] 12:30, 4 July 2010 (UTC)


::I think the term, 'vital force' need not be in the article - we can use, 'natural healing procceses of the body' instead. Vital force is a near obsolete term.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 01:46, 18 October 2008 (UTC)
:Tom, I only have a few minutes right now, but  let me share a thought or two. My greatest unanswered question is "what is the cognitive process of a homeopath in a patient interaction?"  In other words, homeopaths say that every remedy is individualized. Whenever I posed this question to Dana, it was brushed aside, saying that one had to be a trained homeopath to understand.


:::"Natural healing processes of the body" is too long a phrase, and is ambiguous. Conventional medicine certainly recognizes defenses such phagocytes, complement and agglutination, but the patient may be dead by the time they can act in a fulminant infection. Pick something that is a term unique to homeopathy for the things homeopathists want to affect.  
:Odd, but I have written quite a few articles on differential diagnosis in medicine, and some of my most interesting professional work is in expert systems to "individualize" (e.g., what dosage forms are most convenient for the patient and are most likely to be taken on schedule? What other diseases are present -- are there synergistic as well as problem interactions? Are there patient preferences?  Are certain side effects more or less likely?  Somehow, I manage to muddle through this sort of thing, yet I keep being told there are Inner Secrets to Homeopathy that prevent a straightforward explanation. Now, I'm not a classic layman in conventional medicine, but I can't think of a field where I don't have a basic understanding and the ability to quickly get a much deeper understanding -- and also know what I don't know. In the last six months or so, I've had to do the research to do peer interactions, on the specific diseases of people (two- and four-legged) for whom I'm an advocate and case manager -- involving [[human iron metabolism]], [[feline squamous cell carcinoma]], and [[peripheral nerve myelin protein 22]] and [[inflammatory polyneuropathy]]. But I can't begin to understand how a homeopath thinks?


:::You also can't write an encyclopedic article about things that have no fixed definition. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:56, 18 October 2008 (UTC)
:In fairness, I'm not sure how much time I'm willing to expend on homeopathy, at least unless I get comparable collaboration on less controversial, and possibly useful to more people, health science articles (to say nothing of other fields). [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 13:26, 4 July 2010 (UTC)


:::The best description I can think of for the vital force is, "the power for intrinsic healing and/or maintaining [[homeostasis (biology)]]", but should we use the term everywhere in the article?&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 02:04, 19 October 2008 (UTC)
== Luc Montagnier ==


::::Hahnemann thought vital force was acceptable. It's short and to the point. [[Homeostasis (biology)]], however, is not a synonym. Many quite appropriate natural mechanisms deliberately disturb homeostasis for some survival reason. Literally, one can have a particular biochemical pathway in a homeostatic state that is still terribly wrong for the rest of the body. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 02:39, 19 October 2008 (UTC)
French virologist Luc Montagnier has said at a prestigious international conference when he presented a new method for detecting viral infections that it bore close parallels to the basic tenets of homeopathy. This has been published in the 'Sunday Times' (London), as well as 'The Australian' - here's a link to the article: http://www.theaustralian.com.au/news/health-science/nobel-laureate-gives-homeopathy-a-boost/story-e6frg8y6-1225887772305
:I hope one of you (at least Dana) make time (I don't have the time) to insert this matter into this article.[[User:Ramanand Jhingade|Ramanand Jhingade]] 16:26, 5 July 2010 (UTC)
Here's another link: http://epaper.timesofindia.com/Archive/skins/pastissues2/navigator.asp?login=default&AW=1279125246109
[[User:Ramanand Jhingade|Ramanand Jhingade]] 16:37, 14 July 2010 (UTC)


== Results of TGI Survey ==
::I certainly have no intention of amending the article with newspaper articles, especially those that indicate nothing but a "close parallel." Has Dr. Montagnier's proposal been discussed in mainstream journals? 


The results of the TGI Survey needs to be in the body of the section titled, "Popularity of Homeopathy".&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 02:35, 18 October 2008 (UTC)
::The first article, in ''The Australian'', mentions a "memory of water" type argument, and cites rejection by other scientists. I'd note that his Nobel was for virology, not physical chemistry. The second is behind a paywall. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 16:58, 14 July 2010 (UTC)


:Sorry, but the TGI survey is essentially a press release, the website is a marketing agency, and there is nothing whatsoever that makes them authoritative. If you want polling data, get it from a well-recognized polling organization (U.S. examples would be Roper or Gallup, or from specific faculty). [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 14:03, 18 October 2008 (UTC)
:::Hi friends!  Actually, I got sent this link to a recent issue of the "New Scientists" by none other than Nobelist Brian Josephson:  <http://www.newscientist.com/article/mg20727682.300-60-seconds.html>


:::"Clear as a Nobel"
:::Luc Montagnier, the French virologist who won a Nobel prize in 2008 for linking HIV with AIDS, last week made controversial claims that highly dilute solutions of harmful viruses and bacteria emit low-frequency radio waves, allegedly from watery nanostructures formed around the pathogens. Similar claims have been made for homeopathic remedies."  [[User:Dana Ullman|Dana Ullman]] 17:40, 14 July 2010 (UTC)


One problem is the ambiguous nature of the questions asked in any poll.  As written it claims that 18% of Americans trust homeopathyBut what does that mean?  Trust it is safe?  Or trust it is effective? I just saw a [http://www.sciencebasedmedicine.org/?p=203 CAM survey] that indicates that homeopathy has been used by 3.7% of the US population (once only counts). Again ambiguous, of those approx 4% who have used it how many found it helpful? And if 18% of Americans trust homeopathy why have so few ever used it? As always it is very hard to understand what the findings of any given poll really mean. [[User:Chris Day|Chris Day]] 19:32, 18 October 2008 (UTC)
::::That link goes to the daily news summary, not anything on homeopathy.  As quoted, though, they are "controversial claims". No details.  [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:57, 14 July 2010 (UTC)


:Hello Ramanand, this is the talk page.  Please use it. [[User:Chris Day|Chris Day]] 17:58, 19 October 2008 (UTC)
:::::It is necessary to have that link in this article to show that homeopathic remedies are not 'placebos', as some people allege.[[User:Ramanand Jhingade|Ramanand Jhingade]] 15:40, 16 July 2010 (UTC)


== Another ongoing edit war ==
::::::It is another piece in the puzzle.  It is primary research, but it is by a Nobel Prize winner, so it is news about homeopathy.  We shouldn't treat it as scientific fact, but it is a fact that a prominent scientist has made the statement that involves a quality of water.  It is in no way scientific consensus, an in fact may lead to this guys ruin for whatever reason.  We have included news about the British Medical Association's recent position statement concerning homeopathy and [http://www.theaustralian.com.au/news/health-science/nobel-laureate-gives-homeopathy-a-boost/story-e6frg8y6-1225887772305 this article] specifically mentions that statement as well.  This is the draft, so I won't categorically remove something that is written comprehensively, neutrally, and objectively about the subject. [[User:D. Matt Innis|D. Matt Innis]] 12:59, 17 July 2010 (UTC)


Ramanand, can you stop edit warring and discuss the text?  Certainly do not try and hide them as corrections to "''[http://en.citizendium.org/wiki?title=Homeopathy&diff=100399077&oldid=100399065 grammar, spelling and syntax]''". Most would consider the differences below to change the meaning of the text.
(undent) Matt, you give it a perfectly good context--as news. It doesn't show, or not show, anything about homeopathic remedies being placebos, or effective, or ineffective, or any particular clinical correlation. As far as I understand, he's made an observation in physical chemistry and RF fields interacting with water, nothing else. I sincerely hope he's not hurt, as he was incredibly dignified while there were attempts to discredit his initial discovery and characterization of HIV -- his Nobel was very deserved.  [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 19:42, 17 July 2010 (UTC)


:"...and the treatments themselves are generally considered safe, if ineffective by <font color ="darkred">mainstream doctors</font>. Some physicians maintain that homeopathy, like other [[alternative medicine]], is ''relatively'' unsafe because it in some cases might delay the <font color ="darkred">most effective</font>, medically proper treatment."
:My point in providing the link to the NEW SCIENTIST is to verify that this research is "notable," and as such, a short note is worthy here. [[User:Dana Ullman|Dana Ullman]] 05:35, 21 July 2010 (UTC)


:"...and the treatments themselves are generally considered safe, if ineffective by <font color ="darkred">skeptics</font>. Some physicians maintain that homeopathy, like other [[alternative medicine]], is ''relatively'' unsafe because it in some cases might delay the <font color ="darkred">conventional</font>, medically proper treatment<font color ="darkred">, if it doesn't work. </font>"


Obviously this is a case of neutrality vs weight. Please explain why you think the previous version by Hayford is not neutral given the weight of mainstream medicine against homeopathic medicinePersonally I find the word skeptic, as used in this article, is like ''liberal'' as used by Republicans in the US, or ''atheist'' by evangelicals in the US. While technically correct the words are used in a way to give less weight to the opinion. You may consider ''mainsteam doctors'' in that light? So what is acceptable to all? [[User:Chris Day|Chris Day]] (signed late, forgot first time.)
::Matt, you are wonderfully reasonable. Howard is not accurate when he says that Montagnier has "made an observation"Montagnier conducted RESEARCH, and he wrote about it in a peer-review journal. He spoke about it to a group of fellow Nobel Prize winners.  And ALL of this was so notable that the "New Scientist" commented about it...and linked it directly to homeopathy. I have no problem if we choose to have the word "controversial" used in describing this new work.  The fact of the matter is that this new work discusses "electromagnetic signaling" which may help explain how homeopathic medicines may work. [[User:Dana Ullman|Dana Ullman]] 18:29, 9 September 2010 (UTC)
:I'm sorry, I di'n't have time. It's not just the mainstream doctors, but a whole lot of others (if we mention all, it would be too long), so skeptics should be enough. 'Conventional' is required to differentiate it from alternative medicine - most effective is questionable, because it depends on the hospital - treatment in a hospital in Redmond may not be as effective as a hospital in LA.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 02:21, 19 October 2008 (UTC)


::"Skeptics" is not the right word. "Unbelievers" would be closer to the way it's being used here. A serious suggestion: stop trying to compare, stop trying to prove this way is superior to everything else, and just state what you do. I'm sorry, but if the response is always "it's too individualized", few people with any biomedical science experience find that credible. Pharmacogenetics is individualized, yet the diagnostic and treatment protocols can be described. In some of those cases, we may not yet have a specific treatment, but we can be much more specific than "symptoms".
:::Then why isn't the peer-reviewed journal cited, rather than ''Wired'' and ''The Australian''? Further, one may write (e.g., an editorial) ''in'' a peer-reviewed journal, but not have one's work peer-reviewed ''by'' that journal. The peer review process becomes more credible if another independent researcher reproduces of these results. Please provide citations of these events if you want me to believe this is substantive.


::There are times when I don't want holistics, but something specific. If I were to present with a confirmed plague infection ''([[Yersinia pestis]])'', I want my treating physician to know enough about me to know that the second-choice drug, [[doxycycline]], is a better choice than [[streptomycin]]. I'm deaf in one ear and streptomycin can attack the auditory nerve. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 02:39, 19 October 2008 (UTC)
:::Nobel Prize winners, rather by definition, tend to be specialists. One might speak on medicine to a group of Chemistry laureates, and have no special critical review.  


:Good general point, Chris (I, also, missed signing  a note). There are several words or phrases with which people may or may not be neutral, or that there simply is not a generally recognized word or phrase for a key subject. Just below, I am placing a table of such items; '''do not take the first column as being anything but a (hopefully) humorous way of things that don't seem to have widely accepted definitions.  
:::It's interesting that we are still arguing how homeopathic medicines "may" work, when it's rather routine to understand the molecular pharmacology of conventional medicines. Sorry, this still comes across as hand-waving for something with a trivial base of evidence.


:Things in ''italics'' are terms that are ambiguous, have a non-neutral feel, or are less than satisfactory.
::::Have I fired five or six rounds? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 18:38, 9 September 2010 (UTC)


:I'm going to add something that does not quite fit in the table, but where, I hope, Ramanand and I have made some progress. There are terms and practices that are clearly homeopathic. There are terms and practices that are clearly not homeopathic.
== Evidence that homeopathy works ==


:It's perfectly reasonable for a homeopath to say "this is what a homeopath will do", and for a person with a [foo] orientation to say "this is what a ''medical'' practitioner" will do. If, for example, a homeopath speaks of "vital force", we note that as a homeopathic definition and go on. If someone educated in conventional diagnosis and treatment says "this is how drugs are prescribed", we note that as medical and go on. 
I hope one of you (at least Dana) can insert sentences that read something like, "there is scientific evidence for homeopathy", using the PDF for "Scientific framework of homeopathy: evidence-based homeopathy" available at http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewFile/286/354 wherever appropriate. I haven't seen anyone object to it here anyway.—[[User:Ramanand Jhingade|Ramanand Jhingade]] 15:15, 21 July 2010 (UTC)


:I agree, with Chris, that "skeptic" is primarily used here in a deprecatory manner, and its use should be deprecated.
== the word "skeptic" ==


:Where we get into trouble is where terms overlap. "Natural healing processes of the body" is a problem, because physicians augment them as well as using treatments for processes that appear overwhelmed and failing (e.g., acute and severe bronchospasm), or for which there is no known natural defense (e.g., botulism, tetanus, rabies). I am also reasonably convinced that homeopaths and physicians have different definitions of a "symptom".
Wasn't it decided a long time ago that aside from the two existing examples in the article that pro-homeopathy advocates (and anyone else) could NOT use the word "skeptic" in future edits?  Just want to make sure. [[User:Hayford Peirce|Hayford Peirce]] 21:50, 5 August 2010 (UTC)


:When a homeopath refers to [[immunology|immune system]], it's fair for a physician to have expectations of measurable changes [Notes 1 and 2] if therapies are directed at the immune system.
:I remember that as a specific ruling by Larry. In my experience, it's almost always used by advocates of a position; the neutrality policy wouldn't be hurt if it were banned. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 22:41, 5 August 2010 (UTC)


:Could we see if we can get consensus, not deprecatory, terms to fill into any part of the table below? Who knows -- perhaps it might eventually be a suitable subpage? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 15:29, 18 October 2008 (UTC)
::But what about people who ''are'' skeptics? Are we not allowed to say that Michael Shermer - who runs the Skeptic's Society and publishes ''Skeptic'' magazine - is a skeptic? [[User:Tom Morris|Tom Morris]] 23:02, 5 August 2010 (UTC)


{| class="wikitable"
:::As a direct quote or a self-identification, sure. As condescension to disbelievers, no. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 23:04, 5 August 2010 (UTC)
<center>'''Problematic terminology'''</center>
|-
! Concept
! One side's term(s)
! The other side's term(s)
|-
| That form of healthcare practiced by trained and licensed professionals who have never heard of Hahnemann.
| ''conventional physicians'', ''allopath''
| [[Physician]], ''biomedical specialist'', ''non-homeopathic physician''
|-
| That form of healthcare practiced by trained and licensed professionals who believe Hahnemann is the greatest healer in history
| [[Homeopathy|Homeopath]]
| ''Alternative practitioner using homeopathy''
|-
| Someone who believes that Hahnemann defined an essentially perfect system that needs only minor refinements, and that every case is inherently different
| ?? some distinctions as made in [[Chiropractic#Chiropractic approach to healthcare|types of chiropractic approach]]
| [[Physician]], ''biomedical specialist'', ''non-homeopathic physician'', ''mainstream medicine'''
|-
| Someone who believes that Hahnemann defined a system that was superior to what the other kind of practitioner did in the 19th and early 20th century, but was largely made obsolete by processes that can be defined and measured, yet used with judgment appropriate for the individual<font color ="red">, <s>who hasn't tried alternative medicine</s></font>
| ''skeptic'', ''critic''
| Biomedical scientist, ''one trained by the evolved system proposed by [[Abraham Flexner]]''
|-
| Bodily responses to abnormality (symptoms or signs), <u>for which molecular or other objective mechanisms</u> can be described in substantial detail
| ???
| '''no single term''': metabolic [[homeostasis (biology)]] (including [[anabolism]] and [[catabolism]], [[mitosis]] and [[apoptosis]], [[immunology|immune mechanisms]] (see note below) including cell-mediated [note 1] and humoral immunity [note 2]
|-
| Bodily responses to abnormality (symptoms <u> or signs), for which no formal mechanism is defined
| Vital force, natural healing processes of the body<font color ="red">we also call it symptoms amd signs (see my description of vital force)</font>
| ???
|-
| The thing added to a larger amount of something so the thing can be taken by the patient
| ''similimum''
| active ingredient; drug
|-
| Guidance on best treatment
| (medical training and literature (Note 4), [[clinical decision support system]] & materia medica, repertory
| (medical training and literature (Note 4), [[clinical decision support system]]
|-
| The thing administered to an individual to cause a measurable physiologic reaction
| ???
| active ingredient; drug
|-
| The thing administered to an individual to cause a measurable immune response, usually [[active immunity]]. There may be immediate symptoms, but producing them is not a goal
| vaccine/antigen
| [[vaccine]], [[antigen]]
|-
| The something to which the small amount of the other thing can be added
| water (but there apparently are things that are not water, such as ethanol), or, in the body of the article, lactose. ''Is water the only something that has memory''?
| Diluent (water & ethanol), vehicle(lactose)
|-
| Opinion and trust not based on statistical analysis
| Popularity
| Lay opinion
|-
| Administration of a substance to healthy volunteers to determine its effects [Note ]
| [[Homeopathic proving]]
| Phase I [[randomized controlled trial]]
|-
|}
<small>Note 1:</small> [[phagocytosis]], agglutination as by [[eosinophil]]s, nonspecific recognition by [[macrophage]]s


<small>Note 2:</small> changes in [[immunoglobulin]]s, [[complement]], [[opsonins|opsonization]]
::::Ah, but is it? I consider 'skeptic' to be much less of an insult than 'homeopath'! –[[User:Tom Morris|Tom Morris]] 23:06, 5 August 2010 (UTC)


<small>Note 3:</small> terminology conflict: while a homeopathic preparation is considered, by homeopaths, to have the desired effect of producing [[symptom]]s, physicians do not necessarily regard symptoms as physiologic changes. [[sign (medical)|signs]], clinical pathology results, and changes in [[diagnostic imaging]] do indicate change
:::::I think it is -- it comes up repeatedly in fringe articles, be they moon landing hoax, UFO, etc. -- anything not a true believer. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 23:13, 5 August 2010 (UTC)


<small>Note 4:</small> A pair of standard texts such as ''Harrison's Principles of Internal Medicine'', cross-referenced to ''Goodman & Gilman's Pharmacological Basis of Therapeutics'' are regarded as starting points -- but need not be consulted in every case.
::::::If *I* use the word, Tom, it's a compliment.  If Dana uses it, it's pejorative.  That's why Larry (or someone) banned it from this article, if I recall correctly. (I have 20 years' of Skeptical Inquirer on my bookshelf.) [[User:Hayford Peirce|Hayford Peirce]] 23:21, 5 August 2010 (UTC)


:I've commented on each point, so take a look.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 02:49, 19 October 2008 (UTC)
== What the...? ==


::This is a start. Please try not to change the text in the first column, so can work on the definitions in the second and third columns.
<blockquote>Homeopaths respond to these concerns by noting that using homeopathic medicines can delay or reduce the use of conventional medicines that are ineffective and dangerous.</blockquote>


::I struck out <s>who hasn't tried alternative medicine</s>, because it added nothing. Ramanand, please listen to a point: people, such as myself, who do not think that a form of alternative medicine is safe and effective will never, never, try it, no mattery how many times you repeat they should. Would you please stop bringing up that argument, because it isn't going to change anyone's mind?  This article is '''not''' about convincing people to use homeopathy. It is about getting a clear definition of what homeopathy is. By all means, call such people skeptics; it's at least unambiguous.
If this were The Other Wiki, that'd be an instant "citation needed"! I know homeopaths like to bang on about the evil 'allopaths', but do they honestly respond to the [[opportunity cost]] argument with a reversed opportunity cost argument? That's so... indescribably crazy. I certainly would like some verification on that. –[[User:Tom Morris|Tom Morris]] 00:42, 6 August 2010 (UTC)
:Remember our motto: '''be bold''' -- remove it, and let whoever put it there back it up with some facts if they want to restore it. [[User:Hayford Peirce|Hayford Peirce]] 01:42, 6 August 2010 (UTC)


::"we also call it symptoms amd signs (see my description of vital force)" is a real editorial problem. If you are going to use "symptoms and signs", call them "homeopathic symptoms and signs", because you use the term quite differently than in conventional medical usage. I urge you to use "vital force" because it it is short, won't be confused with other definitions, and is historically accurate from Hahnemann. ''Please'' stop redefining terms that are used in medicine, or we will get nowhere. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 16:58, 20 October 2008 (UTC)
::Oh, now we're bold, haha.  It's a response to the use of homeopathy for use with things like childhood ear infections, a commonly self limiting condition that is often treated with antibiotics which have unwanted and sometimes dangerous side effects. It probably could be explained a little better when it's all cleaned up. After all, that is the homeopath response. [[User:D. Matt Innis|D. Matt Innis]] 21:50, 7 August 2010 (UTC)


== Popularity vs. efficacy ==
:::On the other hand, I can point to many medical studies advising against antibiotics in uncomplicated otitis media. Going back to Osler at the turn of the 20th century, he correctly pointed out that "allopathic" drugs were often harmful -- but he then said both homeopathy and (classically defined) allopathy were "cults" that needed to be replaced. One doesn't need to turn to homeopathy to find best practices that avoid both overprescribing and underprescribing. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 21:59, 7 August 2010 (UTC)


There is a relatively long first-level heading, "Tests of the efficacy of homeopathic remedies", and a shorter one called "The popularity of homeopathy". Several citations simply had a URL, so I've started going to the actual references, and putting in a complete citation whenever possible. Reading some of the papers, however, raises questions if some of the work described as evidence for "efficacy" belongs under "popularity".
::::Yup, absolutely agree. [[User:D. Matt Innis|D. Matt Innis]] 01:10, 8 August 2010 (UTC)


No one has objected to these two headings being separate. Are, however, the citations under the correct headings? I have difficulty thinking of papers, in major journals, that do not measure efficacy in terms of an objectively measurable outcome. Such an outcome might be negative (e.g., death) or positive (e.g., laboratory marker within normal limits), expressed over some specific period of time.  If a treatment is efficacious, there will be a statistically significant difference in measurable outcomes -- fewer deaths, more people with normal tests.
== principle of infintesimals ==


Rather by definition, "satisfaction" is subjective. There's a classic anecdote that goes to the heart of satisfaction: "Dr. Smith is such a wonderful, caring doctor. He goes to all of his patients' funerals." Aha! But does Dr. Smith have more patient deaths than Dr. Jones, who has a detestable personality but perhaps better technical skills?
I'm thinking that [http://en.citizendium.org/wiki?title=Homeopathy%2FDraft&diff=100701656&oldid=100701655this principle] needs defining.  I'm thinking that the 'principle of infintesimals' is the concept that is controversial.  Perhaps one of our homeopaths could explain? [[User:D. Matt Innis|D. Matt Innis]] 12:32, 12 August 2010 (UTC)
:Throughout this article, the infinitesimal dose and law of similars have been used interchangeably, but they aren't the same. http://www.similima.com/org20.html has given a brief description of the "infinitesimal dose". The law of similars is just, "using the most similar remedy" - to put it plainly. I don't have the time to check and insert those changes, but I hope you Matt, or may be Dana can do so. The infinitesimal dose can also be defended with the "memory of water" and Monsieur Montagnier's research (see Dana's post above).-[[User:Ramanand Jhingade|Ramanand Jhingade]] 13:49, 13 August 2010 (UTC)
::Certainly using them interchangeably is not accurate. [[User:D. Matt Innis|D. Matt Innis]] 15:05, 13 August 2010 (UTC)
:::I think the term "interchangeably" was wrong to use - what I meant was that the term "law of similars" is used in the article and draft article, when it's supposed to be "the infinitesimal dose", in some places.—[[User:Ramanand Jhingade|Ramanand Jhingade]] 15:50, 13 August 2010 (UTC)
::::So it seems to me that infinitesimal dose needs to be definedThe law of similars can obviously involve large doses of products. Obviously Homeopaths use more than infinitesimal doses in their treatments; otherwise we wouldn't have side effects from a nasal product that has zinc in it. We are not getting this point across. [[User:D. Matt Innis|D. Matt Innis]] 17:47, 13 August 2010 (UTC)


There are four papers, described as meta-analyses, in  Metaanalyses indicating efficacy". Unfortunately, none are available online, so I cannot tell how and if outcomes were measured.  
::::<font color=red>I don't think it's worth the time, since that will also be criticized here (maybe you can use the web-site I mentioned above to do that). The nasal product, "Zicam" wasn't a homeopathic product at all, because it had milligram doses of zinc, which is against homeopathic principles. Homeopathic remedies start with mother tinctures and can go up to higher potencies (more dilute) from there.</font>—[[User:Ramanand Jhingade|Ramanand Jhingade]] 09:50, 23 August 2010 (UTC)


The next four citations (below) are from the section on "Metaanalyses indicating no efficacy". I suggest they are misplaced; they deal with popularity and not efficacy.   First in the list is an article from a lay encyclopedia from the NHS; it is not any kind of analysis, meta or otherwise. Next is a press release with a media contact, which refers to the third; the third is not available free. I have, however, bolded key words in the title of the article. Since they do not mention outcomes, but satisfaction, I contend they belong in the popularity section; they simply have nothing to do with efficacy. The fourth is available online, only refers to patient-reported satisfaction and not outcome, and thus does not measure efficacy
:::::Zicam was marketed as homeopathic, and licensed under special regulations applying to homeopathic products. Sorry, for legal purposes in the US, it ''was'' a homeopathic product. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 15:49, 24 August 2010 (UTC)


#Health encyclopaedia. National Health Service. Retrieved on 2007-07-25.
:::::<font color=green>I know it was, but it was against homeopathic principles.—[[User:Ramanand Jhingade|Ramanand Jhingade]] 15:39, 25 August 2010 (UTC)</font>
#British Homeopathic Association (24-07-2008), Press release: new multi-centre study confirms the value of homeopathy
#Thompson EA, Mathie RT, Baitson ES, et al. (July 2008), "Towards standard setting for '''patient-reported outcomes''' in the NHS homeopathic hospitals", ''Homeopathy'' vol 97:3: pp. 114-121
# Marian F, et al. (2008), "Patient satisfaction and side effects in primary care: An observational study comparing homeopathy and conventional medicine", ''BMC Complementary and Alternative Medicine'' 8: 52, DOI:10.1186/1472-6882-8-52


Many things are popular. If popularity is a measure of efficacy, I suggest thinking about the correlation between efficacy and popularity of politicians. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 23:04, 18 October 2008 (UTC)
(undent) Please do not use color for emphasis.


:There are lots of things in this article which both the skeptics & believers have put in.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 02:55, 19 October 2008 (UTC)
In the context of the  United States, your simple statment that it "was against homeopathic principles" is legally irrelevant, as the FDA makes the decision if something is to be regulated as a homeopathic preparation (or food supplement), exempt from a good deal of the regulation of other drugs, or if it is a conventional regulated substance. The FDA determined Zircam was homeopathic, and, while  I suppose you might argue, in an article about homeopathy and the FDA, such an argument is irrelevant here. If you reject the argument that a governmental organization cannot make such decisions for a country, then I can argue that homeopathy can't be accepted as a national means of practice in India.


::Do you really consider it constructive to keep referring to anyone who raises questions about homeopathy a "skeptic"? I happen to think skepticism is a good thing anywhere, but, as I see your use of the term, it feels like an epithet. Would you like it if a "skeptic" started referring to the "believers" as "charlatans"? An occasional use of "skeptic" is fine, but, over and over again, it sounds like a politicians' code word for "enemyy". [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 18:13, 19 October 2008 (UTC)
With all things that it approves, the FDA depends on the manufacturer's application. More is accepted is fact in a homeopathic New Drug Application that isn't required to undergo controlled trials. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 16:57, 5 September 2010 (UTC)


:::Howard--I'm trying to catch up with the discussion and see if and how I might be of help here.  Personally, I would both consider and label myself a skeptic with regard to homeopathy (and a whole lot of other things, too).  If Ramanand wants to refer to you as a skeptic at least here on the talk page, I say wear the label proudly. --[[User:Larry Sanger|Larry Sanger]] 02:00, 20 October 2008 (UTC)
== Answer to an "unanswered question": Popularity is no metric of efficacy ==


::::If he wants to call me a skeptic, but also answer the questions, that's fine. It's when I ask a substantive question, or ask for a clarification on the article, and get no other answer, that's a problem.
Sorry, but the addition "The simple reason for homeopathy's growing popularity is because it works." is completely unacceptable without overwhelming evidence that it does work. Were this to be accepted without sourcing, the logic could be applied to popularity of politicians, especially not in office, supporting the premises their programs work.


::::Also, dismissing, in the '''article''', anyone who does not accept without question as a skeptic is a real problem. Look though the history and find how many cited references have been dismissed as "skeptics".  The problem is not restricted to the talk page. It appears in the article in a dismissive manner. It is ''also'' used as an evasion when attempting proper clarification of the article in talk page discussion. Just don't call me late for dinner. "Skeptic" spraying, however, is the least of the problems here. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 02:16, 20 October 2008 (UTC)
I propose to delete this. Popularity is relevant to marketing but not efficacy. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 15:48, 24 August 2010 (UTC)


:::::Obviously, if anyone removes a reference ''just because'' it is critical of homeopathy, that is way out of line. That would be a very clear example of a violation of our neutrality policy, and according to our rules, person who ''persists'' in that behavior could be excluded from the project.  For what it's worth, however, I personally haven't been presented with any evidence of that yet, so... --[[User:Larry Sanger|Larry Sanger]] 03:06, 20 October 2008 (UTC)
:Those questions were begging for an answer. If you delete my answer, you must delete the questions preceding my statement as well!—[[User:Ramanand Jhingade|Ramanand Jhingade]] 15:45, 25 August 2010 (UTC)


Well, I haven't removed any references Larry.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 02:18, 21 October 2008 (UTC)
::Your statement, unsourced, was not an answer. It was purely your opinion, phrased as informal commentary. Also, it is a rather sweeping opinion that goes to the heart of the article, with no evidence behind it. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 16:45, 25 August 2010 (UTC)


== Hippocrates, Osler, Hahnemann and his time, and the introduction ==
:::While Howard is right in saying that "popularity" is not a metric of efficacy, popularity is (by definition) its own metric, and statistics about homeopathy's popularity now and in the past has a place in an encyclopedia.  Further, I give reference to a half-dozen
surveys that further verify that people who tend to receive homeopathic care tend to be more educated than those who don't. 


There are two kinds of problem in the lead. I have inserted a temporary heading of '''BREAK'''; the text before that, with some additions, is not unreasonable when a few quotes are added and the deprecation of "mainstream medicine" is deleted.
:::The following link to an article that I authored provides references to this information (please know that I am not suggesting that we link to this article but only to use the references in this article in our encyclopedia listing:  http://www.huffingtonpost.com/dana-ullman/homeopathic-medicine-euro_b_402490.html  [[User:Dana Ullman|Dana Ullman]] 19:14, 9 September 2010 (UTC)


Unfortunately, there is a sense, in much of the article, that Hahnemann's work is contemporary, and there has been, in homeopathic eyes, not much change in medicine since 1805 or so. This sense hurts the legitimacy of the article.
::::''Post hoc, ergo prompter hoc?'' I can give even more studies that verify more people who drink milk become heroin addicts. Popularity is a principally a metric of efficacy -- of marketing. If it is significant here, Lady Gaga should be even more expert than Dana, and probably has a better figure. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 19:20, 9 September 2010 (UTC)


From '''BREAK''' to '''The Basics of Homeopathy''', the rest of the lead text is out of place. Some belongs in other sections.  The first paragraph, which needs sourcing about "commercial" and "user-friendly" since there are multiple definitions, logically is part of the section "Preparation of homeopathic remedies".
== Allopathy ==


Following that, there is a rather rambling paragraph about modes of action. It's perfectly reasonable to say, in the lead, that the mode of action of homeopathic remedies is controversial. There is no generally accepted scientific explanation, although recent research offers avenues of explaration.  Move the materials science material down to memory of water and related topics.  
"Today, "allopathy" is used by practitioners of alternative and complementary medicine, like homeopaths, osteopaths, naturopaths, chiropractors and so on to refer to conventional, western medicine."


Following that, a brief mention of [[randomized controlled trial]]s, their mixed results, and a simple statement that many homeopaths consider the RCT methodology inappropriate for the individualized techniques of homeopathic therapy. I'd like to see a note that some current areas of medical investigation, such as [[pharmacogenetics]], also have issues regarding testing individual therapy; there are, however, some statistical approaches that could be applicable to all forms of individualized therapy.
Since practitioners of conventional, western medicine rarely use the term, however, there's no good argument to insist on calling them allopaths. Yes, there are a few historical references, especially when talking of osteopathic vs. allopathic medical schools, but the term used by conventional western physicians tends to be...conventional western physicians.


The last paragraph with popularity data, if it belongs in the article at all, belongs in the section on "Popularity of Homeopathy".
Ramanand, if I refused to call you anything other than Jean-Paul, would that change your name? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 16:57, 24 August 2010 (UTC)


Working with some of these issues could produce a much better article with a much stronger and more accurate lead. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 01:38, 19 October 2008 (UTC)
:Practitioners of alternative and complementary medicine, like homeopaths, osteopaths, naturopaths, chiropractors and so on refer to conventional, western medicine as "allopathy" even today. If you don't like it, you can add something like, "conventional, western physicians do not refer to themselves as allopaths".—[[User:Ramanand Jhingade|Ramanand Jhingade]] 15:50, 25 August 2010 (UTC)


:Was it a comparison or deprecation?&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 03:00, 19 October 2008 (UTC)
::Each profession defines what it calls itself. That is not the role of other professions. Would you accept the specific words "practitioners of conventional western medicine call homeopaths frauds?"  No?  Then why do you have the right to define a name, regarded by many as either historically inaccurate -- they don't use the principle of opposites -- or a sneering attack?. I wouldn't have the slightest objection if homeopaths called themselves Similarists, Hahnemannists, etc. -- but that is how they characterize themselves, not how they characterize others. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 16:44, 25 August 2010 (UTC)
===Ruling needed===
Mr. Jhingade reinserted "although osteopaths, homeopaths, naturopaths and other alternative medicine practitioners continue to call it allopathy." I will remove this unless an Editor says otherwise, as I believe it has been ruled that one discipline is not permitted to define a name for another. Shall I say "although biologically-oriented scientists consider homeopaths to be quacks? (noise made by the simillium of [[Oscillococcinum]], of course)"  At best, this might go in the [[allopathy]] article.


::If you are referring to "mainstream medicine", it did not read as a comparison, but a deprecation. It recognized no change from Hahnemann's time. In his time, what Hahnemann said was perfectly true: no one knew why drugs worked. The situation is now radically different, but that is not acknowledged. Those last few words about "mainstream medicine" do not add information about homeopathy. They are not necessary to explaining what homeopathy is, but they can easily be interpreted as an attack on treatment that is not homeopathic. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 03:10, 19 October 2008 (UTC)
Osler deprecated both allopathy and homeopathy by the time of the Flexner report, although, somewhat earlier, he had attacked some of the drugs used by self-descibed allopaths. I'd note the latter was 19th century.


== Citation and fact checking on "Medical Organizations' Attitudes" section ==
Be very careful, incidentally, in using "osteopath" versus "osteopathic physician". The latter, in the US, does use "allopath" but in a very narrow context dealing with the history of schools. Undergraduate and graduate medical education from traditionally "osteopathic" or "allopathic" education is largely identical, although some additional manipulative techniques may be taught in ''some'' historically osteopathic programs -- or by qualified faculty in historically "allopathic" programs. Assuming equal certification,  with many boards merging, the scope of practice of DO's and MD's are identical.  U.S. osteopathic physicians do not use the term allopathy in regular practice. Indeed, I know a few that don't use manipulation or any special osteopathic methods. As an aside, in the state of Virginia, to perform acupuncture, one must be licensed as a physician; the two I used were, respectively an MD with a OMD degree from Vietnam and a OB/GYN certification from FACOG; the other was an DO internist board-certified in internal medicine.


I have been verifying the actual cited document against claims made in the article. As mentioned above, a number of URL-only references turn out not to be to journals, but to press releases from homeopathic organizations, government factsheets for laymen, and other less than authoritative sources.  
In the UK -- I can't speak authoritatively  for the rest of Europe -- osteopathy is indeed a CAM discipline and its practitioners' scope of practice is not the same as a physician.  


In another section, the highest standards of citation, quoting in context, and accurate paraphrasing were not followed:
I would add that the opinions of naturopaths are irrelevant to this article.


===Medical organizations' attitudes towards homeopathy===
Could we please stop refighting this revert battleMy impression is that rulings have been made.[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:30, 5 September 2010 (UTC)
First, the article cited the National Center for Complementary and Alternative Medicine. Following the URL, the citation changed the article title to "Statement on homeopathy". when the actual webpage title is "Questions and answers about homeopathy", and completely omitted the subhead (contribution) title of "What has scientific research found out about whether homeopathy works?" The article then described the position as "controlled clinical trials of homeopathy have produced mixed results; in some, homeopathy appeared to be no more helpful than a placebo, but in others, more benefits were seen than expected from a placebo."  But what did the actual text say?
<blockquote>The results of individual, controlled clinical trials of homeopathy have been contradictory. In some trials, homeopathy appeared to be no more helpful than a placebo; in other studies, some benefits were seen that the researchers believed were greater than one would expect from a placebo.</blockquote>


<nowiki>.<ref name=NCCAM-QA>{{citation
:Practitioners of alt. med. still call it allopathy (Look at the American Association of Osteopathic Physicians web-site, the National Center for Homeopathy web-site and so on). I'm sure Dana will support me on this one. I'm looking forward to a ruling too and I believe such a ruling will support the homeopaths' viewpoint, because this article is titled Homeopathy and not, "Criticism of Homeopathy".—[[User:Ramanand Jhingade|Ramanand Jhingade]] 08:44, 6 September 2010 (UTC)
|url = http://nccam.nih.gov/health/homeopathy/#q8
| author = National Center for Complementary and Alternative Medicine, [[National Institutes of Health]]
| title = <!--statement on homeopathy--> Questions and Answers About Homeopathy
| contribution =  What has scientific research found out about whether homeopathy works?}}</ref>></nowiki>


Minor errors and slightly sweetening the text. Next, however, the article text says ('''my emphasis'''): Historically, the [[American Medical Association]] (AMA) was founded in 1847, three years after the forming of the [[American Institute of Homeopathy]] '''in part to slow the growth of homeopathy.''' Unfortunately for CZ accuracy, the citation at http://www.ama-assn.org/ama/pub/category/13638.html  has not one word about slowing the growth of homeopathy.  
::If you are arguing from the perspective of the American Association of Osteopathic Physicians, you are either ignorant of the historical reason they do that, or deliberately making a false argument that American osteopathic physicians, as distinct from osteopaths in Europe, are in any way "alternative". DOs pass the same undergraduate and graduate certifications as MDs.  I suppose I'll have to remind one of my DO friends, a world authority on field and disaster medicine, that he's "alt" and the surgeons shouldn't listen to him. If nothing else, there ''is'' a distinction between alternate and complementary.  


It goes on to say, "Today, the AMA is no longer overtly antagonistic to homeopathy. Their current policy statement says:
::As far as the National Center for Homeopathy website, what part of "one discipline doesn't specify what another calls itself" do you fail to grasp?  I'm sure I can find medical sites that call homeopaths frauds and quacks; would you accept that designation? I'd have to go back into the archives, but I seem to recall that Larry ruled on this a long, long time ago. Dana does not have any editorial authority over what non-alternative practitioners call themselves.  
:1. "There is little evidence to confirm the safety or efficacy of most alternative therapies. Much of the information currently known about these therapies makes it clear that many have not been shown to be efficacious. Well-designed, stringently controlled research should be done to evaluate the efficacy of alternative therapies".(same citation as above.)


But is the full statement as supportive as its point 1?
::If you think these comments are "attack on homeopathy", I refer you to the commentary of Dirty Harry Callaghan regarding the .44 Magnum. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 01:46, 7 September 2010 (UTC)
:2. Physicians should routinely inquire about the use of alternative or unconventional therapy by their patients, and educate themselves and their patients about the state of scientific knowledge with regard to alternative therapy that may be used or contemplated.  


:3. Patients who choose alternative therapies should be educated as to the hazards that might result from postponing or stopping conventional medical treatment.
== Matt's reversions ==


:4. Courses offered by medical schools on alternative medicine should present the scientific view of unconventional theories, treatments, and practice as well as the potential therapeutic utility, safety, and efficacy of these modalities.
Matt, I see you have already reverted what I had added. I don't want to indulge in any "edit warring", so please restore what I had added. I have mentioned the reasons in the sections preceding this.—[[User:Ramanand Jhingade|Ramanand Jhingade]] 16:20, 25 August 2010 (UTC)


I'm sorry, but I am finding much of the writing distinctly non-neutral, selectively quoting, using non-authoritative references, making flat statements where the cited source doesn't say anthing about the subject, etc. Any questioning is variously dismissed as "skeptic", or "biased against homeopathy", or "I don't have time to explain this." [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 22:36, 19 October 2008 (UTC)
:Since you merely identify this a "Matt's reversions", it's difficult to what you specifically have in mind. Did Matt move the questionable material here for discussion?  If he did, then it's appropriate to discuss it here, within policy limits, before it goes back.


:Howard, I'm glad you are trying to improve the quantity and quality of references.  The reference to the founding of the AMA being, in part, to attack homeopaths and other "irregular practitioners" is derived from:  William Rothstein, American Physicians in the Nineteenth Century, Baltimore: Johns Hopkins University, 1972, pp 170-174. As many medical historians know, this text is one of the leading seminal sources for American medicine. 
:If he deleted without making it clear what he was deleting, or why he was making a Healing Arts Editor decision to delete it, he needs to put it here. Otherwise, you cannot simply demand that it be put back without consensus or an Editor ruling. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 16:51, 5 September 2010 (UTC)


:Please note that the AMA has, in the past, maintained a strong anti-homeopathy position, and clearly, they do not maintain that position any longer. You are welcome to incorporate some of the material above, but we should acknowledge that today's view of homeopathy is much more neutral than in the past which was extremely antagonistic. [[User:Dana Ullman|Dana Ullman]] 00:46, 21 October 2008 (UTC)
:I'm in a hurry, but will make a quick reply. I hope Matt brings things here for discussion in future.[[User:Ramanand Jhingade|Ramanand Jhingade]] 08:38, 6 September 2010 (UTC)


::I can do without thanks in improving quality and quantity of references; my concern is that the reference given had nothing to do what was said in the text. I really don't care how many medical historians regard the text as seminal; I care that it was not cited yet it was the source. This is not the first time I have read the actual cited document and found it had little or nothing to do with a claim in the article.
== "Attack piece" ==


::Dana, I'm glad you recognize that the present situation is different than in the 19th and early 20th century. Frankly, I'm amazed about how "stuck" the article seems to be in references going 100 to 200 years back. If one does want to go back to the early 20th century,  Osler said <blockquote>A new school of practitioners has arisen, which cares nothing for homeopathy and less for so-called allopathy. It seeks to study, rationally and scientifically, the action of drugs, old and new.</blockquote>
The statement "Some other researchers claim that there is scientific evidence that homeopathy helps in many problems and diseases[3]" was added with the edit note that "the lede can't be an attack piece."


::I would be delighted to see more current information on homeopathy; there is a [[History of Homeopathy]] article that might be a better place for a good deal of this information. While the AMA is influential today, its membership is a minority of American physicians.  
The lede also cannot be a place where non-substantive opinion can be used to "neutralize" the main thrust of expert opinion. Again and again, it's been pointed out that CZ's current neutrality policy does not mean that equal emphasis must be given to each position.


::John Snow's work from the mid-nineteenth century has survived, but, in general, the work of pre-scientific physicians of that time is largely irrelevant to current practice. I care as much, or as little, about 19th century medicine as I do about 19th century homeopathy.   [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 01:15, 21 October 2008 (UTC)
I recommend deletion of the above statement as far too general, and, for that matter, worded in a manner that really doesn't counter but says "well, yes but..."  There's an old medical story about a radiologist who crawls, bloody and battered, into his emergency room.  Asked what happened, he said it was "consistent with being mugged."  Things in the lede need a bit more substance than "consistent with.[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:19, 5 September 2010 (UTC)


== Some ground rules ==
:I don't see any probs with that ref and I'm sure Dana, the only other Homeopath here will support me on that.—[[User:Ramanand Jhingade|Ramanand Jhingade]] 08:34, 6 September 2010 (UTC)


Here are some brief comments that I hope will help reinforce our ground rules.  I'm sorry I don't have time for more detailed engagement right now.
== Similars and "allopathic drugs" ==


Some Citizens have complained to me that homeopathy's advocates on this page are tending to purge criticisms.  On this I will absolutely put my foot downYou may not do so.  You may maintain that (and say in the article ''how'') homeopaths reject the criticisms, but you may not simply delete points, and source material, simply because you disagree with them or you think they are misinformed. If you have a strong disagreement about a published criticism, you should voice it in the article, rather than removing the criticism. There may be exceptions to this rule, but (I understand) not in several recent cases in the present article.
First, I contend there is no such thing, in modern terms, as an allopathic drugGot any references, such as Goodman and Gilman, that use the term? No, homeopathic texts don't get to define practices in general medicine. Taking a recent addition that I believe must be either radically changed or updated, I quote:


Of course, the "reply, don't delete" rule assumes that a source and criticism are important enough ''from the point of view of homeopathy's critics'' to be includedWhile they can have input of course, this is not ultimately a matter that homeopathy's defenders are best placed to decide.
:"Recent research has shown that some conventional drugs, which are normally used to do something, can do the opposite also - a rebound effect, similar to homeopathy's law of similars.<ref>{{cite journal |author=Kales A, Scharf MB, Kales JD |title=Rebound insomnia: a new clinical syndrome |journal=Science (journal) |volume=201 |issue=4360 |pages=1039–41 |year=1978 |month=September |pmid=684426 |doi= |url=}}</ref><ref>{{cite journal |author=Kirkwood CK |title=Management of insomnia |journal=J Am Pharm Assoc (Wash) |volume=39 |issue=5 |pages=688–96; quiz 713–4 |year=1999 |pmid=10533351 |doi= |url=}}</ref>
<ref>{{cite journal |author=Tsutsui S |title=A double-blind comparative study of zolpidem versus zopiclone in the treatment of chronic primary insomnia |journal=J. Int. Med. Res. |volume=29 |issue=3 |pages=163–77 |year=2001 |pmid=11471853 |doi= |url=http://openurl.ingenta.com/content/nlm?genre=article&issn=0300-0605&volume=29&issue=3&spage=163&aulast=Tsutsui |last2=Zolipidem Study |first2=Group}}</ref><ref>{{cite journal |author=Hohagen F, Rink K, Käppler C, ''et al.'' |title=Prevalence and treatment of insomnia in general practice. A longitudinal study |journal=Eur Arch Psychiatry Clin Neurosci |volume=242 |issue=6 |pages=329–36 |year=1993 |pmid=8323982 |doi= 10.1007/BF02190245|url=}}</ref>.
<ref>{{cite book | last = Reber | first = Arthur S. | authorlink = | coauthors = Reber, Emily S. | title = Dictionary of Psychology | publisher = Penguin Reference | date = 2001 | location = | pages = | url = | doi = | id = | isbn = 0-140-51451-1}}</ref><ref>{{cite journal |author=Kales A, Soldatos CR, Bixler EO, Kales JD |title=Early morning insomnia with rapidly eliminated benzodiazepines |journal=Science (journal) |volume=220 |issue=4592 |pages=95–7 |year=1983 |month=April |pmid=6131538 |doi= |url=}}</ref>
<ref>{{cite journal |author=Lee A, Lader M |title=Tolerance and rebound during and after short-term administration of quazepam, triazolam and placebo to healthy human volunteers |journal=Int Clin Psychopharmacol |volume=3 |issue=1 |pages=31–47 |year=1988 |month=January |pmid=2895786 |doi= 10.1097/00004850-198801000-00002|url=}}</ref><ref>{{cite journal |author=Kales A |title=Quazepam: hypnotic efficacy and side effects |journal=Pharmacotherapy |volume=10 |issue=1 |pages=1–10; discussion 10–2 |year=1990 |pmid=1969151 |doi= |url=}}</ref>.
<ref>{{cite journal |author=Hilbert JM, Battista D |title=Quazepam and flurazepam: differential pharmacokinetic and pharmacodynamic characteristics |journal=J Clin Psychiatry |volume=52 Suppl |issue= |pages=21–6 |year=1991 |month=September |pmid=1680120 |doi= |url=}}</ref><ref>{{cite journal| journal =Pharmacopsychiatry | year =1989 | month =May | volume =22| issue =3| pages =115–9| title =Can a rapidly-eliminated hypnotic cause daytime anxiety? | author =Adam K | coauthors =Oswald I| pmid =2748714| doi =10.1055/s-2007-1014592}}</ref>"


The word "skeptic" ''should not'' be used, pejoratively, to identify those who reject homeopathy in the article.  If there is a need repeatedly to identify the skeptics of homeopathy, you ''may not'' use a term that the skeptics themselves reject.  You ''must'' find a mutually agreeable term.  I suggest "mainstream physicians." "Allopaths" won't do, either, although it certainly can be introduced, and it should be.
First, it's impossible to respond to this deluge of citations without any details. Second, for these to be "allopathic" drugs, based on the "principle of opposites", the papers must include that language. Do they?


It should not be necessary for me to point out that the article can neither endorse nor roundly condemn homeopathy. The article does not take a stand; it presents both (or all) sides on all controversial issues it presents, and leaves it up to the reader to decide for himself. ''The article does not endorse a position.''
Second, it's a leap to equate a rebound phenomenon to allopathy; the dose-over-time, molecular control mechanisms, etc., are much more than "opposites". One of the classic examples of rebound, nasally applied vasoconstrictors, doesn't take place when the dose and duration are properly controlled. In general, if the vasoconstrictor is needed for long enough to cause rebound, use of antiinflammatories, such as corticosteroids, cromolyns, or antihistamines should be under active consideration to replace the  direct vasoconstrictor.


Precisely because homeopathy happens to be a minority viewpoint when it comes to the health issues it discusses, criticism of homeopathy does ''not'' belong in a separate "criticisms" section of the articleI have my doubts whether there is any need for a "criticisms" section at all, but I can't say so until I've read the current version, which I haven't done.
It was with considerable restraint that I didn't immediately move this to the talk page. Ironically, there are very pleasant, collaborative discussions going on in a number of military and history articlesMaybe getting to kill people makes for more restrained discussion. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 19:04, 5 September 2010 (UTC)


Selective and uncritical reporting of references is contrary to CZ's neutrality policy: this makes it appear that ''we officially think'' the literature says such-and-such, when there is legitimate disagreement about whether it does say that.  When, therefore, a "skeptic" raises a question about a statistic such as 18% of Americans, we must absolutely deal with this question.  I am very uncomfortable publishing information about the percentage of Americans who accept homeopathy, when it has not been made clear what "acceptance" amounts to ''in the survey that was performed.''  Therefore, either this essential interpretive information must be included in the article, or the information about the statistic must be excluded. Anything else would be, quite simply, misleading and unscientific.
:The rebound effect is well documented and accepted in medical circles, so please don't delete that sentence or the refs I inserted (I've improved on the way it used to read, so pls take a look).—[[User:Ramanand Jhingade|Ramanand Jhingade]] 08:31, 6 September 2010 (UTC)


More generally, on a topic with this much disagreement, we simply cannot add heaps of studies and statistics to the article ''without adequate explanation'' and without critical responses where such may exist or be possible.  Uncritical reportage of the results of disputed studies has an inherently biasing effect.
::Well documented? "Rebound effect' doesn't appear in the index of the standard textbook, ''Goodman and Gilman's The Pharmacologic Basis of Therapeutics (9th Edition)''. Now, as I have mentioned, the term "rebound" is indeed used in very specific contexts, such as the response of nasal mucosa to topical vasoconstrictors.  


Finally, I want to underscore that if ''anyone'' repeatedly reverts significant parts of the text without explaining and defending his actions here on the talk page, I will consider banning that person.  I would ask those who are following the article more closely to make a list of such unexplained reversions, and provide it to me privately. On the basis of such information I will either issue a warning or, if the problem is very serious, a temporary ban.
::"can lead to the opposite effect, when stopped - a rebound effect, which means they are following homeopathy's law of similars." is not especially an improvement. Of course there are drugs that have adverse effects when stopped inappropriately. Corticosteroids, selective neurotransmitter uptake inhibitors and opioids all come to mind. "Similars" have nothing to do with it, in the sense that a corticosteroid, in a Proving, would be inflammatory.  Instead, the adrenal cortex has reduced its production of endogenous steroids because it has sensed a certain blood level.  


Let me finish on a positive note.  Despite the amount of struggle over this article, or perhaps because of it, this article has grown and in many ways improved, and other articles have spun off.  This is a good thing.  As I like to say, if everybody is equally frustrated, that means that work is getting done and the article isn't ''too'' biased one way or the other. Still, if we can all follow the above ground rules, I think we'll get along quite a bit better. --[[User:Larry Sanger|Larry Sanger]] 16:22, 20 October 2008 (UTC)
::It's vaguely amusing to hear you comment about people ignorant of homeopathy, when there seem to be so many opportunities to be unaware of molecular pharmacology. But, there are different tastes -- where's the eye of newt and blood of bat when you need them? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 01:18, 7 September 2010 (UTC)


I have removed the text below from the article, as the statements are not supported by the reference; an online link to it is now in the article. In addition, I have posted an article on [[Oscillococcinum]].
==Dead link==
http://www.medscape.com/viewarticle/511604  Reference 102 about the value of talking to patients. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 19:08, 5 September 2010 (UTC)


<blockquote>Some [[randomized controlled trial]]s that have tested the efficacy of homeopathic medicines have reported  positive results, but, as mainstream physicians contend that large randomized controlled trials have generally not shown effectiveness beyond [[placebo]] effects, except for the fact that four large trials (totaling 1,194 patients) have found efficacy from [[Oscillococcinum]] 200C in the treatment of influenza.</blockquote>
:Then I suggest we remove the sentence attributed to Vandenbroucke.—[[User:Ramanand Jhingade|Ramanand Jhingade]] 13:56, 6 September 2010 (UTC)


The text above is somewhat hard to parse, and the statistical data is a bit more than "mainstreams physicians contend."  It also does not reflect the studies. There were seven, not four, trials. Four were of treatment and three of prevention; the 1,194 figure above only reflects the treatment trials, not the prevention trials in 2,265 patients.  
==Thankless CZ==
Editing CZ is a thankless job. I'm sure the people who are ignorant about a subject (like Homeopathy) can move on to Facebook, Orkut, Linked in, Twitter or some other networking site/s and make a lot of friends and get to know them really well - we hardly know anything about each other here. Howard, you're probably a nice guy I can get to know better and probably dine with. Sandy, Im sure I can make an interesting 'date'. Why don't y'all look for me on Facebook?—[[User:Ramanand Jhingade|Ramanand Jhingade]] 13:56, 6 September 2010 (UTC)
:I have nothing against friendship, and I do think I've found a number of good friends here. Nevertheless, the essence of what I see as appropriate writing at CZ depends on courtesy, but above all, logic -- western if you will -- and evidence. I have a LinkedIn account, but not Facebook, Twitter, etc. -- and don't want them. On the other hand, I am very active on an assortment of professional mailing lists. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 18:50, 6 September 2010 (UTC)


It was the conclusion of the Cochrane reviewers that only two of the studies were statistically adequate. Looking at all seven, however, they concluded Oscillococcinum had no preventive effect, but showed enough treatment effect to warrant further studies. They did not consider it ready to recommend as first-line therapy.  
:: First off, I greatly doubt either of us would enjoy a date. 'Sandy' is a short form of 'Alexander', and I'm neither unattached nor gay.
:: Second, some of your other apparent assumptions are just as bogus. People generally aren't here for social networking, but to contribute toward building an encyclopedia. Nor does not being an expert on homeopathy preclude contributing.
:: I'm resisting the urge to write a more pointed reply because it would violate [[CZ:Professionalism#What_behaviors_are_unprofessional.3F]]. [[User:Sandy Harris|Sandy Harris]] 23:47, 6 September 2010 (UTC)


I have also removed from the article
==Confusing deletions==
<blockquote>Homeopaths counter that the vast majority of these larger trials tested a single remedy given to every patient without any individualized treatment, suggesting that these larger trials did not maintain external validity to the system of homeopathy and are therefore not valid tests of it.</blockquote>
It's somewhat difficult to tell why things are deleted when the only reasons given are in edit notes, which aren't always easily accessible if, for example, minor edits follow them in the log.


If there is a specific homeopathic publication or presentation that counters these specific findings, it should indeed be in the article, with sourcing. The text above, however, implies that homeopaths reject the specific Cochrane study, but give no specific arguments against it.
This was deleted, possibly due a claim that it was unsourced -- yet it is sourced. It's a reasonable statement and belongs in the article. <blockquote>This does not mean that that people treated with homeopathy do feel better as a result - the clinical literature clearly shows this, but Vandenbroucke suggested that this could be because its practitioners treatments spend more time with people than doctors do. "Even if people give you the wrong explanation about what you seek treatment for, the fact that they spend a long time speaking with you might help," Vandenbroucke suggests.<ref>[http://www.medscape.com/viewarticle/511604 medscape]</ref></blockquote>


I'm honestly puzzled, and would appreciate being educated, on why homeopathic remedies, based on symptoms, would be used as preventive measures. Honest question: does homeopathic theory say that the administration of a remedy will prevent, as well as treat, the symptoms in question? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 22:35, 20 October 2008 (UTC)
"Homeopaths contend that flawed trials cannot be used to show that homeopathic treatment is ineffective <u>(please read the previous paragraph for information about the positive trials)</u>."  This new sentence, especially the underlined words, is argumentative rather than informative.  --[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 18:50, 6 September 2010 (UTC)</i>


:Thanx LarryI am not at all clear how much of your comments are directed to me or to other people hereTo date, I have not engaged in any edit wars, and although I have occasionally deleted some material, I always try to add comments and discussion.  If and when I err here, please alert me.  That said, our lead previously made four references to mainstream doctors not accepting homeopathyThis redundancy, within a short section, seemed non-encyclopedic.  Heck, one could choose to have a "skeptical" comment after every sentence here, but needless to say, that would be too too muchLet's seek a middle ground.
:I didn't do the above editing, though I support itJust because Vandenbroucke says that statement does not mean it is true, especially when there is at present no data to support itThis idea borders on the preposterous that the "extra" time that homeopaths spend with their patients leads to the therapeutic benefits that homeopathic patients experience.  If THAT were the case, then, psychologists would be our finest healers (and sadly, they are not)Although the first interview with a homeopath is typically an hour, the follow-up visits are usually 10-30 minutes, just a little longer than a conventional MD.   


:As for the term "skeptic," I do not see that it is prejorative (in fact, many skeptics of homeopathy are very proud of their skepticism).  I personally think that the term is simply descriptive of some people's attitude towards the subject of homeopathy...and it would seem that "mainstream physicians" is not an adequate description of the variety of people who are skeptical of homeopathy.   
:As for "flawed" trials, see my longer message in the next section where I talk about the importance of "internal validity" in trials AND "external validity." [[User:Dana Ullman|Dana Ullman]] 01:09, 14 September 2010 (UTC)


:As for Howard's statement above, the written info on Oscillococcinum in this article is correct.  I didn't highlight the "prevention" studies because the subject at the time was "large trials" that had a positive result for this medicine.  The preventional trials did not have a positive result, while the treatment trials all had a positive result.  As for prevention trials, I do not at present see any statement in our article that says or suggests that homeopathic medicines have been shown to "prevent" a specific disease.  [[User:Dana Ullman|Dana Ullman]] 00:28, 21 October 2008 (UTC)
==Dana Ullman's thoughts on this article to date==


:::Re the term "skeptic" and "skepticism," I am going to have to disagree and insist that we use another term.  Again, Dana, the point is that ''the other side rejects the term,'' because it is used in a way that implies that there is some presumption in favor of homeopathy.  Suppose a creationist, or a tarot card reader, or some other view you had little respect for, were to insist on labelling the critics of the views as "skeptics" and never as "scientists"; they would prefer to be describe not according to their attitudes to the subject matter, but according to their qualifications: they are scientists.  Let's be very clear.  This is an expert-guided encyclopedia and it reflects the mainstream, expert view first and foremost.  For that reason alone, any presumption is frankly ''not'' in favor of homeopathy.  That is ''why'' it is crucial that there be critical remarks from the point of view of, indeed, mainstream medicine throughout the article. This should not be done in a way so as to interrupt the flow of the narrative, or make it impossible to state the view of homeopathy clearly and even sympathetically. Again, when the back-and-forth in the text of the article occurs, it should be as clear as possible to the reader that such a critical discussion is not done in order to recommend or refute any view of the subject, but in order to give the reader both maximum information and a robust sense that he may make up his own mind as unincumbered as possible by ''any'' dogma.
Sorry to be away from the article for so long...


:::Let's think creatively about other possibilities we might be able to agree upon, ''please.'' I am partial to "mainstream physicians," which is precisely descriptive"Skeptical mainstream physicians" might work as well.  But maybe another word or phrase entirely, like "Critics in the mainstream health community" and the like. --[[User:Larry Sanger|Larry Sanger]] 03:57, 21 October 2008 (UTC)
I am very concerned about this present “draft” of the homeopathy article.  I feel that it has lost its “encyclopedic” tone, and instead, it is a mixture of encyclopedic information along with strong “point of view” skepticismAlthough I do not have a problem with proper skepticism, it is the tone of it AND where it is placed in the article that is critical.


::There is a major controversy in evidence-based medicine over the selective publishing of trials. There is a particular sensitivity about sponsors deciding not to publish results that showed no efficacy, not just where there were no side effects.  AIn this specific case, the Cochrane (i.e., Vickers and Smith) meta-analysis addressed both prevention and treatment trials. If the present article does not mention prevention trials, yet there were sufficently large studies to justify meta-analysis, that seems a deficiency in the article. While you might not be using homeopathic preparations for prevention, there are a substantial number of published studies that do. You may not be saying that medicines prevent things, but there are clearly homeopaths who do, and who have conducted trials to investigate that.  
For instance, in the very top portion of this article are paragraphs #3 and #4 which are not encyclopedic in tone or content.


::Stevinson and colleagues published "Homeopathic arnica for prevention of pain and bruising: randomized placebo-controlled trial in hand surgery" [http://jrsm.rsmjournals.com/cgi/content/abstract/96/2/60]. Jacobs ''et al.'' published "Homeopathy for Attention-Deficit/Hyperactivity Disorder: A Pilot Randomized-Controlled Trial" [http://www.liebertonline.com/doi/abs/10.1089/acm.2005.11.799?cookieSet=1&journalCode=acm]]. A meta-analysis of "Homeopathy for Childhood and Adolescence Ailments" specifically addressed prevention as well as treatment [http://www.mayoclinicproceedings.com/pdf%2F8201%2F8201a7.pdf]].  
I will try to avoid doing “editing” the article myself.  Instead, I will propose here in the TALK section my ideas for what should be said, and I hope that those people who want to maintain a high-quality objective and encyclopedic article will make appropriate changes to the Draft. Needless to say, I will not sign my name, as a Healing Arts Editor, to anything that does not maintain a certain objective tone. And by “objective tone,” I obviously do not mean that this article should just a promo for homeopathy.


::Need I add more citations to demonstrate that if the article does not discuss homeopathic approaches to prevention, the problem is in the article's coverage? I'm not making any judgment if these studies showed benefit or not. The point is, Dana, that if there is significant homeopathic work in any area, that needs to be covered in the article about what homeopathy '''is''', rather than how it is criticized. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 01:01, 21 October 2008 (UTC)
:My sincere thanx for whoever re-formating my contribution so that we can communicate about them in bit-sizeable chunks. Good work[[User:Dana Ullman|Dana Ullman]] 15:37, 14 September 2010 (UTC)


This article should be <blockquote>about what homeopathy '''is''', rather than how it is criticized.</blockquote>. I'm wondering what was wrong with <blockquote>Homeopaths counter that the vast majority of these larger trials tested a single remedy given to every patient without any individualized treatment, suggesting that these larger trials did not maintain external validity to the system of homeopathy and are therefore not valid tests of it.</blockquote>which Dana had inserted?&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 02:52, 21 October 2008 (UTC)
=== Dana on 3rd paragraph===
Ultimately, I recommend some changes in the 3rd paragraph…here’s what I suggest for replacement for this paragraph.


:::What is wrong? It says, in very, very general, nonquantitative terms, that homeopaths don't like trials. It doesn't say how homeopathy can be validated beyond "trust me". There are statistical methods for testing individualized therapies, used in fields beyond homeopathy, but there has been no response, by homeopaths, to descriptions of such methodology. It states nothing positively about homeopathy, just negatively about [[evidence-based medicine]]. Please don't bring up the argument that people who haven't tried it can't judge it; that is meaningless.[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 03:02, 21 October 2008 (UTC)
::While many medical practitioners prescribe some homeopathic remedies, a significant majority of the scientific and conventional medical community (including a number of national medical representative bodies like the British Medical Association), consider homeopathy to be unfounded and pseudoscientific.[1] Skeptics of homeopathy insist that there is no plausible mechanism to explain how the remedies might work, given that many of them are so dilute that they contain not a single molecule of the active ingredient. However, homeopaths and scientists from varied specialties, including Nobel Prize winning virologist Luc Montagnier, assert that there are viable theories about how homeopathic medicines may act, though as yet, no one explanation has been verified. Advocates assert that the homeopathic “principle of similars” is, in part, the basis for modern day immunizations, allergy treatments, and select other conventional treatments (ie, the use of Ritalin and other amphetamine-like drugs used to treat hyperactive children), while critics have compared it to sympathetic magic.


:::Howard, I really don't have the time (I really don't). I'm sure there are statistical methods for testing individualized therapies with respect to homeopathy; for a change why don't you look for those on the Net and include it/them here?&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 03:15, 21 October 2008 (UTC)
::: I wrote the current text. To me it seems accurate and encyclopedic, much better than either what it replaced or your suggestion.


::::First, Gareth and I already discussed such methods as used for [[pharmacogenomics]], and no homeopath responded. Second, why should I go searching for proof that homeopathy is statistically effective? How did it become my problem to prove the homeopathic position from a scientific standpoint?
::: My "While the founder of modern homeopathy was a medical doctor, some modern medical practitioners do prescribe some homeopathic remedies, and some governments do recognise homeopathy as legitimate treatment" instead of your "While many medical practitioners prescribe some homeopathic remedies" gives more arguments favorable to homeopathy, but states them more carefully, your "many" seems dubious to me.


::::You say you are sure there are such methods. Why are you sure? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 03:20, 21 October 2008 (UTC)
::: My "the consensus of medical and scientific opinion is that homeopathy is unfounded." seems to me a simple statement of fact.


::::I probably di'n't have time to see it. I was '''requesting''' you to do so because you have more time than me to do these things. I did see something at, 'http://www.guna.it/eng/ricerca/indice.htm'. There are other such things/sites which I don't have time to look into. Please do the needful. I'm sure you can improve this article by doing so.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 03:34, 21 October 2008 (UTC)
::: I removed the claim that it is "pseudoscientific", which seems to me true but unnecessary here. Criticism is fine; gratuitous insults are not.


:::::I'm really confused. Why should I do the research to support your point of view, when I haven't seen much evidence that it works? The reason I spend time on this is for the good of Citizendium's quality, not to be an advocate for homeopathy. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 03:38, 21 October 2008 (UTC)
::: I do not think the British Medical Association or your "However, ..." or "Advocates assert ..." belong in the lede. The lede needs to be a simple summary of key points. The BMA, Montaignier and Ritalin might all be discussed later, but they do not belong here. [[User:Sandy Harris|Sandy Harris]] 03:34, 14 September 2010 (UTC)


:::::It' only for the good of Citizendium's quality that I'm '''requesting''' you to do so. I also hope that you can include some matter from the memory of water article in the 'Scientific basis of homeopathy' section to make it more neutral. I also feel that you should reintroduce the sentences where the term, 'skeptic' was used - neither Larry nor I consider that term pejorative/deprecatory. Thanks in advance for all the help.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 04:06, 21 October 2008 (UTC)
Greetings, Sandy...we've not interacted yet...let's work together. First, the claim in the present draft that "There is no plausible mechanism..." is false and has no place here. There ARE plausible explanations, though simply none that have been confirmed. [[User:Dana Ullman|Dana Ullman]] 15:20, 14 September 2010 (UTC)


::::::Perhaps I'm confused, but Howard, it sounds to me as if Ramanand is insisting that his view, probably shared by Dana and other homeopaths, be permitted to be included in the article. Are you ''actually'' saying that, no matter how confused or misleading their view is, you have decided it can't be included?  Surely you aren't saying that, but then I can't figure out what you are saying.
:: It depends on the interpretation of the word "plausible". Certainly there are explanations, but I'd say none are plausible. [[User:Sandy Harris|Sandy Harris]] 02:31, 15 September 2010 (UTC)


::::::Perhaps it would be better to work with them on a clarified version of the claim ''and then,'' when it's as clear as it can be made, you simply add a sentence or two explaining how mainstream medical researchers would (or do) respond to such a sentiment. What's wrong with that?  In fact, isn't that what our neutrality policy requires?  Maybe I'm confused, it is a little late. --[[User:Larry Sanger|Larry Sanger]] 04:02, 21 October 2008 (UTC)
: Sandy suggests above that my reference to "many physicians" prescribing homeopathic medicines "seems dubious."  Perhaps it would help if he re-read our article here where in the "Homeopathy in Practice" section gives some specific figures:  "In Europe homeopathy is practiced by many conventional physicians, including 30-40% of French doctors and 20% of German doctors. Some homeopathic treatment is partly covered by some European public health services, including in France and Denmark. In France, 35% of the costs of homeopathic medicine prescribed by a medical doctor are reimbursed from health insurance."...Clearly, the term "many" is not dubious. [[User:Dana Ullman|Dana Ullman]] 15:48, 14 September 2010 (UTC)


::::::Larry, Howard - that is what all of us want, i.e.both sides views should be incorporated in this article. Howard relatively has a lot of time, so I was hoping he could improve the article by incorporating both sides views.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 04:11, 21 October 2008 (UTC)
:: See the discussion under "unsupported assertions" above. Those claims do belong somewhere in the article, if they can be supported, but the lede as it stands seems to me a good summary. [[User:Sandy Harris|Sandy Harris]] 23:21, 14 September 2010 (UTC)


:::::::No, I don't think all of us want. Homeopathy is not a mainstream opinion. If the homeopaths want to put out their view, and accept that it simply does not have reasonable support by the criteria that would be applied to any medical therapy, fine.
: I have a question for Sandy and Howard and other skeptics.  At present, in this lede, there is the sentence: "To a skeptic, the 'principle of similars' is merely an appeal to sympathetic magic."  Out of curiosity, do you believe that there is a certain wisdom of the body?  Do you believe that the human organism tries to adapt to infection and/or stress by creating symptoms in order to survive?  If you answer YES or MAYBE to EITHER of these questions, then using drugs that mimic the body's defenses make sense, and as such, we HAVE to delete or change this ill-founded sentence.  Please also remember that the "high potencies" is only a part of homeopathy and that most homeopathic medicines sold in health food stores and pharmacies today are in small, material doses.  It is inappropriate (and inaccurate) to assume that ALL homeopathic medicines are in doses beyond Avogadro's number.  [[User:Dana Ullman|Dana Ullman]] 16:34, 14 September 2010 (UTC)


:::::::I don't see an equal set of views. One has testable models and consistent scientific theory. One has vitalism and spirit forces. It seems rather like religion and science; they are completely different models of thinking. As far as I can tell, you want homeopathy to be accepted on faith and testimonials. I have no idea how to improve something that has yet to give me any plausible reason that it works in any explainable way. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:29, 21 October 2008 (UTC)
:: That sentence is fine. What we believe is not at issue. The paragraph is trying to summarise the position about homeopathy of skeptics and critics. I'd say that, if anything, it understates their revulsion. Granted, other parts of the article should give a much more favorable view, but the negative views should be there as well. [[User:Sandy Harris|Sandy Harris]] 23:21, 14 September 2010 (UTC)


{{nocomplaints}} (I removed a comment that concerned the qualifications of others to participate here.  This sort of comment is contrary to [[CZ:Professionalism]].)
:::Individual belief is outside the scope of the article, but no, I don't think there is a "wisdom of the body", and, using the medical definition of [[symptom (medical)|symptom]], the body doesn't create any symptoms -- the mind does. Symptoms are subjective, and signs are objective. A sign may be evidence of a defense mechanism, but it's far more likely to be evidence of a disease process.


::::::::I agree with your attitude on the merits of the issues 100%, Howard. That said, I'm afraid you have missed my point.  I am not asking you to endorse the position that "there is an equal set of views here," whatever that might mean precisely.  I am asking you to ''let homeopathy state what you regard as nonsense.'' You lack the right to prevent Ramanand and Dana from expressing some view, even if it is a nonsensical view, of mainstream science and trials and so forth. But I frankly don't understand why you don't simply say, "Fine, now let me explain how mainstream science ''responds'' to that." After all, that is what you are, quite irrelevantly, insisting on so strongly here on the talk page.  If so, then let them have their say, and (essentially) say what you say in response to it ''in the article.''
:::The great fallacy I see here is the assumption that proving-based drug mimic the actual defenses. The body's direct defenses against ''[[Clostridium tetani]]'' exotoxin in [[tetanus]] are immunologic. Those defenses are supported by administering synthetic tetanus immune globulin -- we learned to avoid the horse serum preparation as too risky -- to give initial passive immunity, and tetanus toxoid to build active immunity. These don't "mimic" the defenses; they '''are''' the defensesThe body really doesn't have defenses against the neurologic effects of the toxin, but benzodiazepines, neuromuscular blocking agents, baclofen and dantrolene provide what, I suppose, could be called "symptomatic" relief. Without getting into all the receptors, we have a pretty decent idea '''how''' these drugs reduce the spasticity; we don't need to go the route of finding similars.  


::::::::The neutrality policy means you ''cannot'' speak only for yourself here; you speak for everyone, including your intellectual sparring partners. You ''must'' try to express the homeopathic view as sympathetically as possible--while expressing the mainstream reaction to it as sympathetically as possible as well.
:::I'm not opposed to using unusual explanations when there are no better ones. "Wisdom of the body" sounds like something for a Religion Editor. I do use complementary methods when I have some reason to believe in a favorable risk-benefit. As soon as I hear that something is risk free, alarm bells go off. There are always tradeoffs. I'm facing a terrible one now, as the American Veterinary Medical Association described euthanasia as a means of comfort care that has the side effect of death -- yet I have a beloved cat who has a greater will to live than any human I've ever encountered. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 23:56, 14 September 2010 (UTC)


::::::::And this goes for ''both'' sides.  I am tempted to remove everyone who has been disputing from this article for a time, and let others have a crack at it, simply on grounds that there is good evidence on both sides, I'm afraid, that people are trying to make the article speak with their own biases, and not working together to present ''the dialectic'' clearly.  There is far too much concern that our own biases be reflected in the article. Anyway, enough of this--I think I've made my point (once again). --[[User:Larry Sanger|Larry Sanger]] 04:49, 21 October 2008 (UTC)
The text you are questioning is "There is no plausible mechanism to explain how the remedies might work, given that many of them are so dilute that they contain not a single molecule of the active ingredient. To a skeptic, the "principle of similars" is merely an appeal to sympathetic magic." I think that is OK as it stands.


:::Larry, I tried to express the homeopathic view sympathetically. Remember that table where I tried to get a translation of terminology? No cooperation.
It could be replaced with something that both states the skeptical position better and mentions that not everyone is skeptical:


:::<blockquote>"Fine, now let me explain how mainstream science ''responds'' to that."</blockquote>
: To a skeptic, there is neither any solid evidence that homeopathy is effective nor any plausible explanation of why it should be, and the "principle of similars" is merely an appeal to sympathetic magic. Homeopaths, however, believe that they have good answers to these criticisms.


:::There has been nothing to which a mainstream science response can be made. Mainstream medicine uses controlled experiments, measurable phenomena, peer review. This keeps coming back to anecdotes and "trust me". [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:59, 21 October 2008 (UTC)
::Close.  Let me urge that [[sympathetic magic]] show as a wikilink, as it is not just a throwaway pejorative, but an anthropological term that shows up across many cultures. Consider dropping the "merely". When I wrote the article on sympathetic magic, it wasn't intended to disparage, but to explain a cultural pattern.


::::Au contraire.  What you ''just said'' is a mainstream medical response, it seems to me.
::Is it necessary to bring up both the Avogadro argument ''and'' similars in the lede, purely from a standpoint of complexity?  Yes, I understand that potentiation is an argument that can be countered with the Avogadro point, but similars seem more basic than potentiation in understanding the core argument of homeopathy.


::::As for that table to translate terminology, I would like to see it moved to [[Homeopathy/Catalogs]] and perfected. --[[User:Larry Sanger|Larry Sanger]] 13:47, 21 October 2008 (UTC)
::I am ''not'' trying to be argumentative when I say that arguing that the principle of similars is an equivalent or superior explanation, to a drug that was designed using molecular structure-activity relationships, is inflammatory. It's one thing for the homeopaths to say why their own preparations work, but it's pushing too hard to say that the homeopaths have better explanations for the drugs developed under different paradigms. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 02:46, 15 September 2010 (UTC)


===Responses, have been indented to incoherence===
=== 4th paragraph===
First, I shall announce that yesterday, I made the best rye bread I have ever made, which is making me feel better this morning. Alas, I know of no networking technology that can transfer fresh-baked bread.
I believe that the present 4th paragraph has NO place in the top section.  Discussion of the “possible dangers” from the patient or the doctor’s decision to not use conventional treatments has NO place here.  If others wish to insert this information under its proper section, I do not have a problem, though we must then acknowledge:  Homeopaths respond to the possible dangers from using homeopathic medicines in replacement of conventional medical care by asserting that there are much greater dangers by using conventional medicines as a first method of treatment.


Larry, apparently I misunderstood that you wanted a much more extensive "mainstream medcine" response. I read some of the homeopathic request to mean that I was being asked "go on the net" and find evidence of solid statistical methodology and results that made the response "equal" in their responses. I was also frustrated by what seemed to be, simultaneously, citing of statistics about questionable merit such as popularity and referrals, but either selectively reporting things that were there, or denying there was any way to make homeopathy compatible with mainstream standards of substantial evidence.
: It probably needs mention of the fact that homeopaths retort that conventional medicines may also have large risks. I'm inclined to think it does belong in the lede, since these risks are a basic issue about homeopathy. However, I don't feel remarkably strongly about that and would be interested in hearing other opinions. [[User:Sandy Harris|Sandy Harris]] 03:44, 14 September 2010 (UTC)


Note that last: evidence, not proof. While every field has its charlatans and outright idiots, there is a trend in medicine to have the humility to accept that diagnosis and treatment need constant revision and improvement. With essentially the same genetically related heart problems, I've outlived my father for 18 years, and he spent the last several years as a cardiac cripple. I look back to what was available at the time of his serious decline in health, and most of the relevant drug classes had not been invented.  
::I would prefer to see it go unless the homeopaths present a statistical risk-benefit argument, based on modern medical practices, not 1900, that the hypothesis is true that the clinical outcome is better with homeopathic treatment than medical or no treatment. The risks of most medical treatments are quantifiable, as are the benefits, with the understanding that statistical aggregates do not apply to individuals.


I also think of some interdisciplinary medical seminars I've attended, and was fascinated to see, for example, orthopedists and chiropractor working to bring their specialized expertise to clinical problems, with both listening to an expert in pain physiology to hear techniques that could complement their work.  While I recognize there are different schools of thought in chiropractic, and $DEITY knows enough (substitute non-family-friendly term) in orthopedics, the point is that everyone was looking for, and finding, common ground. No one was saying the other field couldn't ask hard questionsMost importantly, there was an eclectic, but general consensus about using evidence, and fitting treatments to mechanisms we can always understand better.
::There are any number of times I've chosen something with significant risk, because there was reasonable evidence the risk was greater than the benefit. Obviously, a cardioplegia solution that stopped my beating heart was risky, but the risk of not having the open-heart surgery was greater. There was reliable data for risk at each stage of the procedure.   


Contrasting those workshops with the discussion here simply makes me sad. Oh, there's no question that someone may offer an aphorism, about the clinical encounter, from Osler, but no one is stuck in the professional jealousies and defensiveness of 100 to 200 years ago. While this article clearly needs some historical context, some of the most bitter statements, as well as quotes justifying homeopathic positions, are over a century old &mdash; sometimes two. Let the material about the early homeopathic and medical squabbles move to [[History of Homeopathy]]. Include enough history to understand terminology (and there's the "catalog"), but concentrate on current work. I would be delighted to explain how bad conventional medicine was at the time of Hahnemann. A century later, Osler observed that there were principally two drugs that consistently did something (digitalis and morphine), with roughly ten more that have stood the test of time. I take a sometimes daunting range of medications for the same diseases as my father, but, running through the list mentally, as many as 12 didn't yet exist at the time of his death. How often are new homeopathic methods demonstrated?  How often are things added to ''materia medica''? When do homeopaths remove remedies from use because they have been demonstrated to be unsafe (including avoiding effective non-homeopathic treatment) or to be ineffective?
::When other children would chant "your mother wears army boots," I'd point out that they were part of her uniform. The "medical treatment is more dangerous", without substantial data, rings equally relevant to me. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:34, 14 September 2010 (UTC)


There is almost nothing in the article about homeopathy as complementary medicine; there is a great deal about homeopathy as an alternative to mainstream medicine. There are some awfully vague comments about using medical testing and diagnosis, but I am still completely bewildered by how the disciplines can work together. At the same time, I have both personal and scientific exposure to very effective collaborations between mainstream and complementary practitioner.
::: "I would prefer to see it go unless ..." is not clear to me. Are you saying that text on homeopathic rejoinders should not be inserted, or that we should follow Dana's suggestion and remove the current 4th paragraph from the lede? [[User:Sandy Harris|Sandy Harris]] 05:30, 14 September 2010 (UTC)


:I have occasionally made errors, and when it is noted, I acknowledge it.  We all make errors.  I sincerely hope that Howard will acknowledge this error below.  Ramanand above noted, This article should be <blockquote>about what homeopathy '''is''', rather than how it is criticized.</blockquote>. I'm wondering what was wrong with <blockquote>Homeopaths counter that the vast majority of these larger trials tested a single remedy given to every patient without any individualized treatment, suggesting that these larger trials did not maintain external validity to the system of homeopathy and are therefore not valid tests of it.</blockquote>which Dana had inserted.
::::Unless the homeopathic rejoinder has strong statistical support, it should not be in the article. It's one thing if there is a formal risk-benefit analysis proving a hypothesis, but if it's no more than "well, medical treatments are dangerous," it's irrelevant defense. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 06:25, 14 September 2010 (UTC)


:Howard then responded, "What is wrong? It says, in very, very general, nonquantitative terms, that homeopaths don't like trials. It doesn't say how homeopathy can be validated beyond "trust me".
In due respect, the formal risk-benefit analysis needs to go BOTH ways.  What evidence do you have for the "dangers" of receiving homeopathic treatment...and please do not give individual cases.  I do have access to numerous cost-effectiveness studies showing significant cost savings to people who utilize homeopathic medicines.  [[User:Dana Ullman|Dana Ullman]] 15:34, 14 September 2010 (UTC)


:My concern here is that Howard doesn't seem to understand what is meant by "external validity," which is an important statistical concept. The test of one homeopathic medicine in the treatment of a condition for which it is rarely, if ever, used is NOT a good, adequate, or "scientific" test of homeopathy or the homeopathic method.  The Shang analysis actually included one trial on the use of Thyroidinum in the treatment of "weight-loss."  This study had no external validity.  Likewise, Shang analysis included tests of Oscillococcinum in the PREVENTION of the flu...as well as a separate inclusion of a study of Oscillococcinum in the TREATMENT of the flu.  There is a long history of use and success in using Oscillo in the treatment but NOT the prevention of the fluA competitor (Dolisos, Inc.) to the makers of Oscillo in France funded the prevention study, which again, had no external validity.  It was no big surprise to find out that this medicine didn't prevent the flu.
:Bluntly, it does not need to go both ways. Homeopathy is desperately trying to claim a place at the table in the face of enormous evidence that molecular medicine is effective. It seems your position is that homeopathy and medicine are of equal status and that every claim against homeopathy must be counterattacked by one about medicineIf, indeed, homeopathy is so much an alternative to medicine, this is useless.


:These poor scientific studies are akin to prescribing antibiotics for viral infections and then asserting that "antibiotics do not work for infections." That statement is misinformation.
:Incidentally, it would be wise for you to identify your financial interests in the promotion of homeopathy, such as (from http://www.homeopathic.com/main/bio_dana.jsp):
:*Dana Ullman, M.P.H. (Masters in Public Health, U.C. Berkeley) is "homeopathic.com" and is widely recognized as the foremost spokesperson for homeopathic medicine in the U.S.
:*Dana founded Homeopathic Educational Services, America's largest publisher and distributor of homeopathic books, tapes, software, and medicine kits. For 10 years he served as formulator and spokesperson for a line of homeopathic medicine manufactured by Nature's Way, one of America's leading natural products companies.


:Ultimately, there are rare instances where one homeopathic medicine can be successfully prescribed to people with the same disease, though most of the time, effective homeopathic treatment requires individualized treatment. In sum, Howard, I certainly didn't say or infer that homeopaths do not "like trials" (we just don't like poorly designed trials that are set up to not adequately test homeopathy). [[User:Dana Ullman|Dana Ullman]] 16:51, 21 October 2008 (UTC)
:See Bob Badgett's developing article on [[conflict of interest]]. It is one thing for a practitioner to charge for professional services, but it is generally considered unethical for physicians to refer patients to testing facilities, publications, etc., from which they derive income.  


::Dana, I agree that a specific trial should only be testing the homeopathic remedy for which it is designed, but it is still not clear to me whether this precludes clinical trials or not? Obviously precribing is highly individualistic so this make selecting the patients for a trial more problematic. Are there any cases of trials that have occurred where a homeopath does control the remedy but it is also blind from the perspective of the homeopath and the patients?  And this comes to another issues that i have still not really wrapped my mind around. If everything is so individialised how is it possible to have homeopathic remedies available for sale from a store?  I just can't understand how remedies are robust enough to be sold from the shelf yet a population of patients cannot be found that that all use the same remedy in a blind clinical trial. [[User:Chris Day|Chris Day]] 17:25, 21 October 2008 (UTC)
:You are the one making the claims that medicine is so dangerous. I didn't make claims about ""dangers" of receiving homeopathic treatment", which is a change of subject. I will say, however, that it is dangerous to seek homeopathic treatment in lieu of medical treatments of established efficacy. Now, that seems a backing-off from the dangers of conventional medicine, but there seems a dearth of such studies from sources not vested in homeopathy. Again, these studies need to be overwhelming to dispute the CZ policy of providing the mainstream view.  


::::Chris, please see [[Talk:Homeopathy#Statistical methods for testing highly individualized therapies]] below, as one type of methodology that is being used, in experimental mainstream medicine, for trials of highly individualized therapy. Gareth also discussed this. It would be one alternative.
:"NPOV", incidentally, is WP-speak and discouraged here.  


::::There is also a body of research into research methods on treating what are called "low responders". These are patients without many alternatives, but where an individualized treatment may work. I emphasize that methodologies are still being explored. If, however, there is a genetic correlation with low responders who do respond to a particular therapy, one of the approaches may be not to try to treat immediately, but first to look for the genetic pattern, and, perhaps try, ''in vitro'', a monoclonal antibody or other agent tailored for the individual problem. Only if the circulating abnormalities can be controlled would human trials be considered. For a collaboration among homeopaths and physicians, there would have to be an investigation to find what is common, at a molecular basis, among patients with similar symptoms. I cannot believe that the number of symptom combinations come within orders of magnitude of the possible genetic combinations. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 19:23, 21 October 2008 (UTC)
:Incidentally, apropos of being encyclopedic, how about contributions other than your single subject? Some of us are interested in building an encyclopedia, not fighting a never-ending battle with single-issue advocates or, as Sandy responded to Ramanand, social networking. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 16:48, 14 September 2010 (UTC)


:::Dana, first, stop personalizing what I understand and don't understand. You really would not want to hear my opinions, which would not meet standards of courtesy.
:: Wow, Howard, you're now getting disperate...and I'm sorry to see this. First, for your information, I was personally asked by Larry Sanger (the founder of Citizendium) to edit here, and he asked me to become a Healing Arts Editor.  I have never hid any fact about my background.  In fact, most people appreciate my knowledge and expertise, except those few people who are threatened by facts, research, references to data, and the substantiation of information.


:::Second, external analysis is generally considered a statistical technique for market analysis, although it is used in some community-level needs analysis in public health.  
:: You and Sandy were asking me for "evidence" that conventional medicine has certain risks.  While I could have laughed at this seemingly innocent (or naive) request, I simply responded by asking you to provide evidence that there was danger to homeopathic treatment.  Instead of providing this evidence, you have chosen a different strategy to get your bias into this article.  Let's avoid such tactics...and let's try to work together to write something fair, accurate, verifiable, and encyclopedic. [[User:Dana Ullman|Dana Ullman]] 22:26, 14 September 2010 (UTC)


:::To cut to the chase, if homeopathy is not going to accept being tested by statistical methods widely used in mainstream medicine, ignoring suggestions of statistical methods that mainstream medicine is using for highly individualized therapies, and have their model treated differently than any other field of health sciences, well, no. There isn't going to be any cooperation, and homeopathy is not going to be taken seriously. If you have peer-reviewed information, in a mainstream journal, on how external analysis is used in drug testing for efficacy, present it.  
:::No, I don't believe it is possible to collaborate with you to write something that is fair, accurate, and is not far more supportive of the benefits of homeopathy than is supportable by the views recognized by the bulk of medical opinion and data. I believe the best I can do is point out evasions, selective and often inaccurate statements about pharmacology, misquotations (e.g., saying Sandy or I asked for "evidence" medicine has risks), and what I believe to be a significant conflict of interest. I do so in discussion here, to be sure other members of the community see it, rather than jump into revert wars.


:::Stop condescending and making cracks about my "new found passion" or "desire to improve the citations". Give widely accepted, peer-reviewed examples where external analysis has demonstrated efficacy.  
:::I have never suggested that medical treatment does not has risks; medical treatment ''always'' has risks. What I find to be hand-waving is the implication that homeopathy has no risks, including the delay of effective treatment.  


:::Which is it, Dana? In one posting, you say homeopathy has not been shown to prevent anything, but, in another posting about statistical validity you mention, IN ALL CAPS, that a different homeopathic trial focused on promotion. '''paging a philosopher''' some input, please, on the [[Law of the Excluded Middle]]? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:28, 21 October 2008 (UTC)
:::You will note that I have asked for an Editor ruling on what I consider continued misues of von Behring as an authority that homeopathy works. I find it sad that regardless of what was done to design a treatment, the data-free argument that similars ''might'' be an explanation continues to be brought up.  


::::Let me underscore that all the personalization of the dispute here is out of line.  It is inconsistent with [[CZ:Professionalism]], which I urge everyone to review if you have not seen it recentlyThe Constabulary would be justified in removing a number of personal remarks above, but let's just say that we won't see any more of them. --[[User:Larry Sanger|Larry Sanger]] 02:29, 22 October 2008 (UTC)
:::Larry Sanger is not a health professional, and, I suspect, asked you to be a Healing Arts Editor because you are visible in that fieldI would be much less antagonistic to your contributions were you to focus on what homeopaths believe and do, rather than the frequent -- and frequent inaccurate -- attacks on medicine, such as your condescending remark that there are no antifungal and antiviral agents of demonstrated efficacy, and, indeed, demonstrated risk. Indeed, the risk of unmodified amphotericin B has led to significant molecular work to reduce toxicity. You give the impression, however, that Hahnemann got it all right in the early 19th century, and medicine continues to get it wrong.


== Statistic given in article does not appear in cited source ==
:::Professional collaboration does not require that participants like one another. It does not help when they are patronizing, and, if they can't take focused criticism without changing the subject, perhaps the kitchen of knowledge is a bit too hot. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 22:53, 14 September 2010 (UTC)


I have deleted this bit:
Howard, my concern about your editing is that you are just fabricating fights.  You wrote above that I said
"there are no antifungal and antiviral agents of demonstrated efficacy."  Where (!) did I say OR simply imply that?  Nowhere!  I even repeated my point that we all have to be careful in making broad statement such as the "collective weight of evidence".  THIS is what I mean by "straw men."  You create arguments with yourself by making up what I say. 


:42% of [[medicine in the U.K.|British doctors]] refer patients to homeopaths.<ref name="Fisher"/>
:Where did you imply that? In an unsigned entry following mine of     Howard C. Berkowitz 04:25, 14 September 2010 (UTC)
:''I am surprised and even a bit shocked to hear your assertion that antibiotics are effective for viral and fungal infections,''
:Obviously, I disagree, because I then listed numerous examples of antimicrobials effective against such infections.
:If you want to accuse me of starting fights with myself, I'll simply conclude that one of me will always win. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:38, 15 September 2010 (UTC)


The article says that 42% of British doctors "refer patients to homeopaths."  I found no such claim in [http://www.bmj.com/cgi/content/full/309/6947/107 this article,] which was cited.  All that I could find on a scan of the article was "up to 37% of British general practitioners use homoeopathy."  There was also this: "Those who use homoeopathy regularly do so in about a quarter of their consultations, the proportion being higher for hospital and private specialists."  A text search for the string "42" did not bring up the statistic.


Our article should note that ''this source'' is a review article and not reportage of original research findings.  For that reason it is difficult to tell exactly what the statistics mean, without looking up the article's sourcesDoes the 37%, or 42% (???), represent the number of British doctors who ''regularly'' refer patients to homeopaths?  Who have ever even once used it themselves, i.e., tried it out?  Who use it personally (i.e., not to treat their patients but themselves)?  Who use experimental therapies on their patients, that also happen to be used by homeopaths?  What?  I am sure that 37%/42% does not represent the number that ''regularly use'' homeopathy, for the simple reason that the article does also say that "those who use homeopathy regularly do so in about a quarter of their consultations," which seems to imply that there are those who use homeopathy, but not regularly.
To clarify (again), my point is not that there are no risks to homeopathic treatmentHowever, IF we wish to highlight that there are certain risks to homeopathic treatment, we also have to acknowledge that it is widely recognized that there are much greater risks from conventional medical treatment.  [[User:Dana Ullman|Dana Ullman]] 03:43, 15 September 2010 (UTC)


The statistic may also not be significant (and this should be stated in the article perhaps after a little discussion) due to the ''nature'' of the referrals, i.e., it is entirely possible that people are referred to homeopaths ''because patients specifically ask for such referrals,'' not because the physician would make such referrals generally.  Moreover, it would be important to know to what extent these physicians refer to homeopaths as a "last resort," after conventional medical solutions are tried, and patient and doctor are desperate to try things even if they may have no effect at all.
: Certainly we should say somewhere in the article that there are also risks with other treatments, and that one of the arguments for homeopathy is that many of its remedies are low-risk. However, "it is widely recognized that there are much greater risks from conventional medical treatment" strikes me as something an encyclopedia cannot subscribe to without a lot more evidence.


I dwell on this point only to underscore a point that I believe Howard, Chris, and others are making here: these sorts of statistics ''absolutely do not'' speak for themselves.  If you want to make such claims in the article, they have to be either properly clarified, or else qualified, i.e., mentioning the uncertainty about how they are to be interpreted.  ''Even if'' we have a neutrality policy, the license that the policy gives us all, to state our views forthrightly, ''does not also'' license us to make claims that are unsupported by the evidence (as the 42% statistic ''appears'' to be) or to make claims that are very vague and, due to their vagueness, misleading as to the evidence.
: In any case, I do not think a detailed discussion of risk issues belongs in the lede. I am inclined to thin the lede should raise the question, and in my opinion the current text does that adequately. [[User:Sandy Harris|Sandy Harris]] 04:12, 15 September 2010 (UTC)


I believe that all these claims should be checked ''and removed'' if similar problems to the 42% problem are found.
::I agree that a detailed discussion is out of place in the lede. If I may, I'll offer a fairly well-established risk of using homeopathic therapy as a first resort: [[myocardial infarction]] (heart attack). Assuming there are no contraindications to thrombolytic therapy, the window for optimal benefit from thrombolysis is 3-6 hours after onset, with declining benefit out to 12 hours. Thrombolysis can reverse the damage to the heart muscle if done within the window. I can cite any number of conditions where death can occur in hours or days  without definitive therapy--tetanus is one. Of course, the best treatment for tetanus is prevention -- and TDAP and other immunizations are not designed by the principle of similars.


Also, to the person who added the 42% statistic--may we please have an explanation?
::It's one thing to say that homeopathic remedies might be lower-risk in non-emergent situations, but that isn't what is being said. Of course, one could also say "it is widely recognized that there are much greater benefits, in serious conditions, from appropriate conventional therapy."  No, appropriate conventional therapy does not, as been charged, extend to antibiotics for uncomplicated otitis media. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:38, 15 September 2010 (UTC)


Finally, as to the point that such statistics are trying to make--that homeopathy enjoys the status and honor of ''intellectual support'' from medical doctors in these percentages--well, that doesn't follow from the statistics cited.  Someone might refer, or use, homeopathy, and do so being entirely skeptical of it--almost, as it were, superstitiously.  Human beings are like thatAnd on ''that'' point surely surveys have been done, and I'd like to see the resultsWhen asked directly, "Do you believe that homeopathy and its remedies are (1) always, (2) usually, (3) sometimes, (4) rarely, (5) almost never, or (6) never more effective than placebo?" what do they say (in different countries)? --[[User:Larry Sanger|Larry Sanger]] 14:32, 21 October 2008 (UTC)
:::In due respect, no one (!) has said or suggested that homeopathic medicines should be a treatment of first resort for heart attacks.  THIS is what I mean by my concern for your tendency to create fights/arguments.  Let's both avoid creating straw men.  That said, I agree with Sandy that the lede should not have a detailed discussion of risks issues, though I would think that we might all agree that it is widely recognized that homeopathic medicines themselves are "basically safe." Also, can I ask us all to try to avoid inserting our own comments within the comments of other writers because it makes it challenging for people to determine who is saying what.  Thanx.  [[User:Dana Ullman|Dana Ullman]] 16:51, 19 September 2010 (UTC)


:Slow down, Larry. The exact source of the reference for 42% of British physicians referring patients to homeopaths is: R. Wharton and G. Lewith, Complementary Medicine and the General Practitioner, BMJ, 292, June 7, 1986: 1498-1500.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=3087494
::::If it's alternative medicine, then it is the first resort. If it's complementary medicine, then there should be guidelines for the scope of practice of homeopathy. In the past, however, Ramanand has said homeopathy should be a first reatment for all manner of conditions. There was an extensive argument about acute asthmatic attacks, which, as I remember,  


:Actually, simply referring a patient to a homeopath is relevant for several reasons. First, the doctor takes on liability issues in doing so, and therefore, s/he doesn't refer unless there is some type of respect or trust that the doctor has in the homeopath or the homeopathic method. In either case, this IS relevant.  It may be of additional interest to discover how often a doctor provides a referral, and such present or future surveys that deal with this issue can be added here, but I see no reason that surveys published in high impact journals should be ignored. [[User:Dana Ullman|Dana Ullman]] 17:03, 21 October 2008 (UTC)
::::I am not creating a straw man. Please document when homeopathy should not be the treatment of first resort. Otherwise, I'll assume alternative medicine with no limitations.  


::Dana, as I said, ''the source cited by the article,'' marked as Fisher, ''did not contain the statistic.''  If you can support the statistic with a ''different'' source, that's great, but it does not address my point, which was serious. I'm afraid I'll have to ask again: ''who'' put the statistic, with that citation, into the article?  I ask because I want an explanation of the error from that person. Was it perhaps an innocent typo, somehow?
::::Let me clarify my position. I would tend to say that homeopathic medications, themselves, are basically safe. I am very concerned that homeopa<u>thy</u>, as a system of treatment, can be as deadly dangerous as a non-surgeon trying an advanced surgical procedure. You have yet to give information that documents what limitations homeopaths accept.  


::It seems we can say that in this 1986 survey of 145 mail-in questionnaire respondents, who were Avon, England GPs, 42% had referred at least one patient to a homeopathic doctor or non-medical practitioner. --[[User:Larry Sanger|Larry Sanger]] 02:56, 22 October 2008 (UTC)
::::Please stop with the straw man accusations. I do not believe that any consensus is possible between alternative (i.e., not complementary) medicine and coventional medicine. Actually, I'd be far more likely to consult a shamanic healer than a homeopath, as there's a fair bit of documentation that shamans have a good understanding of psychosomatic medicine. I don't know what consensus could exist between someone that rejects the idea of treating the pathogens of infectious disease, and someone that has an understanding of modern microbiology. We, sir, are not on the same side and will not be. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:24, 19 September 2010 (UTC)


===Questioning the answer of 42===
=== Rest of article ===
Doesn't anyone read Douglas Adams?
Further evidence of the strong POV and non-encyclopedic tone of this Draft is:


While I'd have to look for current data, entirely too many antibiotics are prescribed by mainstream physicians, often to meet the expectations of a patient or parent, but knowing full well that an antibiotic will do nothing for a self-limiting viral infection. They have, however, exposed their patients to toxicity, and the population as a whole to a source of drug-resistant bacteria. My point is that this is not a matter of pride to the medical profession, but something it is trying to fix.
--under OVERVIEW:  The first two sentences are “attack sentence.”  It is clearly inappropriate to provide critique of a subject before adequately describing it FIRST.  Those sentences must be removed or placed elsewhere.


Something worth knowing: how does homeopathy keep reinventing itself and improving its process? Does it?
: I'd say at least the entire first paragraph and probably the whole "Overview" section should be deleted. None of it is real overview of the field. [[User:Sandy Harris|Sandy Harris]] 03:50, 14 September 2010 (UTC)


What are the shared, not the oppositional, concepts? There has been at least one individual, [[Harold Griffith]], fully trained in conventional and homeopathic methods, who received the Nobel Prize in Medicine or Physiology for contributions to surgical anesthesia. When does such a person not insist that homeopathic methods are the best for everything? Sorry, I'm extremely tired of asking and asking about when homeopaths refer, or use medical techniques in which they are trained, and be told "it depends". There are too many consensus guidelines, such as back pain, giving strategies for synergy, to accept that there can be no communication.
:: I agree with Sandy.  There is no need for this "Overview" section, though I do believe that we need to place some of this information about the status and popularity of homeopathy in a section "Homeopathy in Practice." [[User:Dana Ullman|Dana Ullman]] 15:45, 14 September 2010 (UTC)


Constant repetition about popularity, about how much mainstream medicine is out to get the homeopaths, and how dangerous mainstream medicine may be is not effective communication. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:10, 21 October 2008 (UTC)
-- under OVERVIEW:  Some sentences here are just confusing, especially this one and especially its last phrase:  They are interested too in why some studies appear to have positive outcomes—do these reflect real efficacy, or can they be accounted for by flaws in study design or in statistical analysis, or "publication bias"—the tendency for small studies with chance positive outcomes to be published while studies with negative or inconclusive outcomes are not.


:Howard, please note that homeopaths seem to honor the Hippocratic tradition with great rigor and vigor than conventional doctors do ("First, do no harm.")Homeopaths prefer to try and sometimes exhaust safer methods before resorting to the "bigger guns" (and more risky therapeutic measures).  That said, each situation requires its own guidelines based on the medical urgency, the degree of known efficacy of the conventional medical treatment, and the initial response to homeopathic treatment.
-- under HISTORICAL ORIGINS, it is confusing and surprising how or why Paracelsus was described as an “astrologer.”  This field was not a primary area of his contributionsJust as the bio for Isaac Newton does not describe him as an astrologer, even though he actually wrote more on THIS subject than on mechanistic physics, we editors here know that Newton’s primary contributions to the modern-day have nothing to do with astrology.  Needless to say, people here who want homeopathy to sound “quackish” tend to provide this biased information.


:Charles Frederick Menninger (1862-1955), the founder of the famed Menninger Clinic, was the head of his local (Topeka, Kansas) homeopathic societyHe asserted, "It is imperatie that we EXHAUST the homeoapthic healing art before resorting to any other mode of treatment if we wish to accomplish the greatest success possible." (1897)...quoted on page 124 of my book, "The Homeopathic Revolution" (I can provide the original reference if desired)[[User:Dana Ullman|Dana Ullman]] 00:22, 22 October 2008 (UTC)
-- under HISTORICAL ORIGINS: Inaccurate information has been provided about the present status of the word “allopathy.”  There is a long AND significant modern-day usage of this term by conventional medical organizations, medical schools, and state and national governmentsEvidence for this is at:  http://en.wikipedia.org/wiki/Talk:Allopathic_medicine (see “Hopping's huge list of links). Clearly, the term “allopathy” is still in extremely common usage, and it is simply inaccurate to say that it isn’tIn this light, Osler’s quote has no meaning here, though it may have a place in the article on “allopathy.”


::Dana, I believe the ground rules were to state what homeopaths did, not continue a struggle against mainstream medicine.  
-- under THE LAW OF SIMILARS: As much as I like the subject of “hormesis,I do not associate its application with the law of similars nor do I know any reference to that.  As such, the word “hormesis” has no place in THIS section.  We could replace this word, hormesis, with the word “pheromones” because these substances are known to have a powerful effect in extremely small doses AND it is widely known that pheromones from one species are only sensed by those of a “similar” species.


::Charles Menninger was a great psychiatrist, who died around the time the first effective drugs for mental illness were being introduced (i.e., [[chlorpromazine]]) in 1952. Have you some equivalent works of homeopathy from prestigious psychiatrists in current practice, equipped with a bit more understanding of brain chemistry? While I think Menninger was a distinguished physician for his time, and set standards for ethical practice, the main therapeutic technique he introduced, and is still found valuable, is art therapy.  Were he to be reincarnated, I'd greet him with joy, and then suggest he take a year or two of current clinical science, and probably two years or so of supervised fellowship, before I'd want him to treat anyone whom I cared about.  Bluntly, I don't much care what he had to say about homeopathy, because he was unaware of sixty years' better understanding of neuroscience, cognition and psychopharmacology &mdash and I am not referring to drugs alone. [[Cognitive behavioral therapy]] and other methods also have replaced many of the psychodynamic methods he used. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 00:44, 22 October 2008 (UTC)
-- under CLINICAL TRIALS TESTING THE EFFICACY…
There are many sentences and paragraphs here that I could recommend changes, but I will emphasize those that are most important or most incorrect:


:::Er...guys?  This doesn't have anything to do with the article.  It seems to be a pointless debate, unless a particular part of the text rests on its outcome, which I doubt... --[[User:Larry Sanger|Larry Sanger]] 03:00, 22 October 2008 (UTC)
I recommend removal of the following short paragraph & its accompanying quote.


::::Larry, I agree completely. It is pointless, and I would make the observation that the continuing appeals to sources 50, 100, and 200 years old are pointless. It is also pointless for another contributor to lecture me about my motivation, my interpretation, etc., as has happened repeatedly. Aside from an admittedly silly reference to 42, my questions at the start of this subsection were serious suggestions about data, if homeopathic experts can provide it, which would strengthen this article. It may be that I am asking questions that are not easy to answer, but my intention is to help be sure that articles here are comprehensive. It's really rather tiresome to continue to get patronizing comments directed to me, and not to the subject. Speaking as a published author myself, I also question the propriety of exhortation to read one's own books. When I cite my material, I try for public domain first, then may paraphrase or quote the particular published material as relevant to the article. I have never asked anyone to get my commercial material. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 03:21, 22 October 2008 (UTC)
::While many of these have indicated positive effects, generally, trials that are larger high-quality trials have tended to show little or no statistically significant effects, as was concluded by the authors of the second Lancet study cited above when they re-analyzed these trials.  
:: “There is increasing evidence that more rigorous trials tend to yield less optimistic results than trials with less precautions against bias.[98]


== Homeopathy/catalog added ==
My explanation:  First, the quote does not verify the sentence it is supposed to substantiate.  Second, the article it quotes also asserts that it is a general finding in ALL clinical research that the higher quality trials tend to show less positive results.  Third, the fact of the matter is that there are many high quality trials published in “high impact” journals that have shown statistically significant effects, including the four trials by Reilly, et al, the four trials on the treatment of influenza using Oscillococcinum, and the three trials on childhood diarrhea by Jacobs, et al.


At Larry's suggestion, I created the subpage "Homeopathy > Catalog" at http://en.citizendium.org/wiki/Homeopathy/Catalog (how '''do''' you wikilink to a subpage?). It is intended to compare and contrast terminology used in homeopathy and mainstream medicine. It has a basic assumption that, in certain cases, there are either terms of art, or words that are used differently.
We need to be careful in our review of research to avoid skewing the facts with “fudge” words. For instance, one could say that the “collective evidence” of the thousands of studies conducted by Thomas Edison was that electricity was not possible (because only ONE experiment in 1,000+ worked).


If mutually agreed words can be found for the same concept, that would be a pleasant surprise. What I do hope to accomplish is, effectively, a dictionary between different systems. Some terms may not translate or be rejected by one side or the other; making that clear would be useful.
The challenge that we have in describing the efficacy (or lack of it) using homeopathic medicines is that we have to evaluate internal validity (how “high quality” were the trials?) AND external validity (is the specific medicine tested commonly used by homeopaths to treat people with that specific condition?). Skeptics of homeopathy tend to evaluate the internal validity issues and totally ignore the external validity issues…and BOTH are essential.  To ignore external validity is akin to saying that antibiotics do not work for infections because the “collective weight” of studies on viral, fungal, and bacterial infection shows that these drugs do not work for this common group of diseases. Get it?


[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 18:23, 21 October 2008 (UTC)
:No. I don't get it, because I can demonstrate, ''in vivo'' and ''in vitro'', that antibiotics do work for viral, fungal and bacterial infections.  This is hand-waving and hardly encyclopedic.


[[Homeopathy/Catalogs]] --[[User:Larry Sanger|Larry Sanger]] 03:03, 22 October 2008 (UTC)
:I have repeatedly challenged you to respond to why homeopaths seem uninterested in the sort of trials used for customized pharmacogenomic medicine, which do have internal and external validity, and never have gotten an answer. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:25, 14 September 2010 (UTC)


== Statistical methods for testing highly individualized therapies ==
:: I am surprised and even a bit shocked to hear your assertion that antibiotics are effective for viral and fungal infections, but I have no interest in arguing with you about these subjects here, though these strange assertions may influence your credibility with others. I take much more seriously your unfounded assertion that homeopaths are not interested in research that has internal and external validity. What is your evidence here? 
It's probably easier to create some notes again than find the previous postings in the archives. Gareth had some very eloquent things to say on the topics.


There are emerging areas of medicine where the traditional [[randomized controlled trial]] has methodological problems. Among them is [[pharmacogenomics]], in which therapy is individualized not only based on the medical history, physical examination, and routine laboratory and imaging studies, but also on genetic analysis and specialized laboratory tests suggested by such analysis. Among a group of patients with similar symptoms, it may be found that a specific bad protein is causing damage, but the reason for the protein being damaged could be controlled by a number of different genes, each responsible for an intermediate step in the synthesis of the final protein.
:::Shocked? Now, if you are holding to the generally obsolete assertion that antibiotics are purely natural products, that's one thing. Let's see...viral? Neuraminidase inhibitors for influenza (as well as the older amantadine and rimantidine), ribavirin for Lassa fever and possibly other hemorrhagic fevers, protease inhibitors (as part of HAART) in lowering HIV levels...well, interferons might or might not be considered antibiotics, but have distinct roles in treating viral diseases. Fungal? Amphotericin B (amphotericin B lipid complex, amphotericin B cholesteryl sulfate, and liposomal amphotericin B); the conazole series; griseofulvin; flucytosine -- and that's not considering topical-only agents. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:07, 14 September 2010 (UTC)


Approved immune-based treatments, such as monoclonal antibodies to [[tumor necrosis factor-alpha]] in rheumatoid arthritis, reduce the level of the final protein. By concentrating on that final protein, a large enough group can be collected for a conventional clinical trial.
::::Howard, you're missing my point here. My point is that one must be careful using the term "weight of evidence" because such terms group together various disparate treatments for various disparate conditions.  Although I used the term "antibiotics," perhaps I should have used a name of a specific antibiotic, thereby showing that it may be effective for one type of infection but not for "all types" of infection.  Likewise, testing homeopathic Arnica for one ailment may prove efficacious, but testing it for two other ailments might show that it is ineffective.  One should not say that the "weight of evidence" is that Arnica is not effective. Instead, it is more accurate to say that Arnica is effective one condition but ineffective for two others.  Get it now?  I hope so...


Increasingly, however, we are aware that the protein synthesis error could happen at an intermediate step, controlled by one of a long list of genes. The least invasive and most effective treatment may be to administer a neutralizing agent that only affects the step where some protein is not created correctly, as defined by genes.
::::My intention is not to "fight."  My intention is for us to work together to provide verifable accuracy.  [[User:Dana Ullman|Dana Ullman]] 22:37, 14 September 2010 (UTC)


At present, the trial approach being considered is to have a clinical team examine the patient, and prescribe what they consider to be the appropriate treatment. That prescription goes to the pharmacy, where the pharmacist opens the next sealed envelope, which says if this patient is to be assigned to the control group or to the experimental group. If the patient is assigned to experimental, then the exact prescription, individualized to that patient, is made up; otherwise, it will be a control treatment or placebo.
:::::Now I am confused. When you challenged fungi and viruses, it seemed you were challenging the existence of antimicrobial agents (a better term than antibiotic) for those organisms. I gave counterexamples.  


At the end of the trial, measurable outcomes of success &mdash; not subjective measures such as "satisfaction" &mdash; are compared between the experimental and control groups. Every patient in the experimental group may have received a different, personalized modified monoclonal antibody. If there are better outcomes in the experimental group, the trial confirms the '''methodology''' of selecting treatments rather than the treatment proper.  
::::No person with reasonable competence in [[infectious disease]] suggests there exists Panaceamycin, good for everything, any more than, presumably, Arnica is good for everything. Antimicrobial agents have reasonably well defined spectra, but, since they are directed against mutable living organisms, any competent hospital has a table ("antibiotogram") of the preferred agents for community-acquired and hospital-acquired infections ''in that locality''.  


Such an approach, it would seem, could be applied to homeopathy. Has it? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 19:23, 21 October 2008 (UTC)
::::Now, does the "weight of evidence" support appropriate antibiotic use? Yes! "Appropriate" does not include using antibiotics for self-limiting conditions unlikely to be affected by any antibiotic. Appropriate means considering the overall clinical picture -- sounds like the argument you make about syndromes -- such as not using penicillin G for exquisitely penicillin-sensitive streptococci, if the culture shows coinfection with [[Staphylococcus aureus]] or other penicillinase-secreting organism. One has to consider potential development of resistance, as well as the practical means of administration--if there is no one qualified to inject a parenteral antibiotic in home care, the antibiotic is irrelevant no matter how effective it may be against the organism. If there's a choice in a patient with a hearing loss, you avoid the especially ototoxic aminoglycosides.


== Specific immune benefits of chickenpox and measles? ==
::::Incidentally, I was just scratching the cognitive process in determining how to treat an infection. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 03:03, 15 September 2010 (UTC)


There is a reference to Randall Neustaedter's ''The Vaccine Guide'' which is cited for a homeopathic belief that there are immunological benefits from contracting measles and chickenpox, rather than immunizing against them. Could someone, with access to this book, describe these benefits?
:: Just as doing double-blind and placebo controlled research testing surgical procedures have their methodological and ethical challenges, research on homeopathy has to be sensitive to the method itself.  You cannot just test a homeopathic medicine and its effects on a bacteria in a petrie dish, nor can I test acupuncture by putting a needle in a petric dish full of bacteria. You've been told this many times in the past, and yet, you repeatedly feign ignorance about homeopathy and homeopathic research.  Please...you're a smart guy. Let's discuss research that does exist.  [[User:Dana Ullman|Dana Ullman]] 15:59, 14 September 2010 (UTC)


Have the benefits of chickenpox been weighed against the future risk of [[herpes zoster]]? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 22:19, 21 October 2008 (UTC)
:::I repeat: there are usable methods that have been described for pharmacogenetic medicine. Let the clinician diagnose the individual treatment and send orders for it to the pharmacy. The pharmacy breaks the blinding code and dispenses either the ordered individual treatment or the control arm, the latter which may or may not be placebo. The safety committee monitors, and, assuming the study goes to completion, statistically evaluates the hypothesis that the experimental treatment arm is superior to control.


: Howard, this subject doesn't have a place on THIS article. I have, however, read studies that show that people who experience measles have a statistically significant reduced rate of atopic disorders.  Although one might conclude that measles provides some type of immunological benefit here, another interpretation could be that the measles vaccination increases atopic states. There is a body of literature on the "hygiene hypothesis.[[User:Dana Ullman|Dana Ullman]] 00:29, 22 October 2008 (UTC)
:::Incidentally, the piece of laboratory glassware is a Petri dish. If, however, you are referring to bacterial sensitivity testing, production tends to be done with radiochemistry, radioimmune reactions, or immunofluorescence. Consider me dumb since I don't know I'm feigning ignorance about homeopathy. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:07, 14 September 2010 (UTC)


::Are you ignoring the first paragraph and answering the second? If you are answering the second, fine. Your call. I might point it out myself.
:::"I've been told"...but by someone I find plausible? You have yet to answer my question about the cognitive process of a homeopathic session, claiming that only a homeopath can understand it, yet no medical discipline makes such a claim of inner mysteries. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:07, 14 September 2010 (UTC)


::As far as the first point, are you saying the inadequately sourced claim about advantages of measles and chickenpox should go? If so, I agree. This is an encyclopedia: if controversial things are said, they need verifiable sourcing. They indeed may be controversial and stay, but there should be readily available information from credible sources.  
::::Howard, I am perfectly able to describe the cognitive process of a homeopath, but I don't think THAT has a place here.  I've told you this before (many times!), and yet, you repeated request it.  I'm writing this again because it seems that you don't want to remember.  Sadly, you consistently seem to want to pick a fight, and you make these strange claims about homeopathy and homeopaths without evidence. To me, it just seems that you have a chip on the shoulder.  I have no problems with you making verifiable statements or asking questions, but I do have a problem with you creating boogey-men when none exist.


::Or did you want to talk about atopy, the Prausnitz-Küstner reaction, and better ''in vitro'' alternatives? [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 00:51, 22 October 2008 (UTC)
:::: I will say this:  homeopaths usually prescribe their medicines for the overall "syndrome" of the patient, not just their "disease." [[User:Dana Ullman|Dana Ullman]] 22:46, 14 September 2010 (UTC)


== Editing "Trials in humans" section for flow and citations ==
:::::I keep repeating it because you keep refusing to answer it, which I remember very well. Apparently, homeopathy is unique among healing arts and health  sciences in not addressing cognition in practitioners.


Just to keep everyone informed, I have made several edits on the "Trials in humans" section, first trying to clarify the flow. While I'm still working on it, I tried to move the introductory text by a CZ contributor to the beginning of the section, and put the various trials under subsections below them. Of course, when there is CZ commentary on a particular trial or meta-analysis, the comment belongs in that subsection.  
:::::I suppose that if I can't do better than century-old immunology and pronouncements that regardless of the molecular pharmacology that went into developing a drug, our old buddy similars ''might'' be the real explanation.  


Material on ''The Lancet'' controversy was especially hard to follow, because multiple references were all under the same footnote number. I broke them into separate footnotes, and added at least some material about what each author(s) actually said; it was otherwise very confusing.
:::::Sadly, you consistently want to pick a fight with anyone who doesn't regard homeopathy as the greatest thing for health. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 23:14, 14 September 2010 (UTC)


With respect to the Cochrane meta-analysis of [[Oscillococcinum]] (I've started an article on this preparation), I found the actual conclusions of the free summary to be a bit different than the one word, "promising", that described the work.
--Under GOVERNMENT AND INSTITUTIONAL…
-- If we choose to include reference to the Great Britain’s House of Commons’ Science and Technology’s report on homeopathy, we have to make it clear that this report was voted on by an extremely small minority of its members.  Of the 14 members, 10 did not consider this issue worthy of voting.  Ultimately, a “majority” of only THREE members voted for this anti-homeopathy report.  Of these 3 votes, two members were so new to the Committee that they did not attend a single hearing on the subject of homeopathy.  The third vote for the “report” came from Evan Harris, a vitriolic antagonist to homeopathy who was not re-elected this year, losing to a 20-something year old political neophyte.  Finally, because this report was “advisory” only in nature, the health minister overruled it and didn’t accept its conclusions.  If anyone wants to make reference to THIS report, we have to add these important facts.  I personally suggest that we do not cover this complicated and inconclusive decisions.


There was a section under "trials in humans" that was not about trials, pertaining to over-the-counter remedies. I moved it to be with other material on nonprescription remedies, and changed the section from "Popularity of Homeopathy" to a more comprehensive and neutral "Popular opinion and over-the-counter homeopathic remedies". "Popularity", like "Criticism", may not be the best of encyclopedic headings. "Public opinion" may be even more neutral than "Popular opinion".
It should also be noted that whoever wrote the above was obviously also aware of these facts and choose not to present them. This type of biased reporting should not have a voice here.  Let’s strive for more encyclopedic objectivity.
[[User:Dana Ullman|Dana Ullman]] 01:21, 14 September 2010 (UTC)


The last paragraph, under the "Lancet" subheading, appears to be text from a CZ contributor. In its first sentence, it contains a '''value judgment (my emphasis)''' that I believe needs to be sourced and explained: "Several of these published responses remarked '''(incorrectly)''' that the researchers evaluated only those studies that met certain criteria for “high quality” scientific investigations."
:Repeated defenses of homeopathy, with nothing more than supposition and coincidences, don't belong here either. In my opinion, Mr. Ullman, you will not regard anything short of an article that gives homeopathy as much credibility as conventional medicine as acceptable -- and that, sir, is a promo. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:25, 14 September 2010 (UTC)


I am continuing to follow the citations in the last two sections. Some appear to be evaluating patient satisfaction or subjective assessment as endpoints. While that is a perfectly legitimate thing to study, it should not be confused with the type of endpoint that is generally used in [[evidence-based medicine]].  
===Logical fallacies===
Take the proposed statement "Advocates assert that the homeopathic “principle of similars” is, in part, the basis for modern day immunizations, allergy treatments, and select other conventional treatments (ie, the use of Ritalin and other amphetamine-like drugs used to treat hyperactive children), while critics have compared it to
sympathetic magic. "


If I do find subjective endpoints, I propose to create a subsection under what may be renamed again, currently the "Popular opinion..." If formal studies of individual patient subjective response to treatment, as opposed to general opinions of homeopathy, were done, those are significant and need to stand apart from general opinion surveys. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 02:35, 22 October 2008 (UTC)
If anyone used the principle of similars to plan these treatments, there might be a case. I sincerely doubt, however, that this was ever done; the advocates making after-the-fact, observational rather than molecular, correlations that are extremely dubious.  Take a modern immunization, especially an acellular one -- it is designed on a molecular basis to produce desired immunoglobulins and other specific substances; similars were not involved in the design.  It's rather hard to say that "similars" is a ''better'' explanation than what the molecular pharmacologists intended, and can demonstrate.
 
Are there homeopathic provings that demonstrate that large doses of cromolyns cause basophil and mast cell degranulation? If not, the molecular explanation that they desensitize the granules, and in turn block the release of histamine and other inflammatory messengers, is a much better shave with Occam's Razor.
 
I hope we do not have as lengthy a debate on the Tooth Fairy, especially from advocates that are America's leading spokesman for tooth fairies and thus have a financial conflict of interest. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 01:57, 14 September 2010 (UTC)
 
:Just to throw yet another bit of reality, the use of amphetamine-like drugs, as well as non-amphetamine drugs such as Strattera, for attention deficit disorder &mdash; not limited to children &mdash; and not discussing other psychotropic drugs is, to put it mildly, showing selection bias. There's as much evidence of neurotransmitter effects than of "similars". Further, if one were to generalize to other psychotropic drugs, one couldn't use the principles of similars to produce hypomania in a normal control.  It has repeatedly been demonstrated that lithium carbonate, for example, is not euphoriant. In high doses, it's a depressant -- remarkably so, since the subject will be dead. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:25, 14 September 2010 (UTC)
 
:: We cite in this article a quote from Emil Adolph von Behring (the "father of immunology") who asserts, "In spite of all scientific speculations and experiments regarding smallpox vaccination, Jenner’s discovery remained an erratic blocking medicine, till the biochemically thinking Pasteur, devoid of all medical classroom knowledge, traced the origin of this therapeutic block to a principle which cannot better be characterized than by Hahnemann’s word: homeopathic."  Whether physicians today (or yesterday) refuse to believe that the "principle of similars" is utilized in medicine, it still can be asserted that they are consciously or subconsciously utilizing it.  This is NOT to say that ALL drugs are prescribed by this principle (Howard creates a straw man argument with his reference to lithium carbonate).  Further, just because there are other explanations for how or why Ritalin works does not take away the fact that the "similars" principle may also be at play.  [[User:Dana Ullman|Dana Ullman]] 16:14, 14 September 2010 (UTC)
 
:::Ah yes. von Behring. 1901 Nobel Prize for 19th century work. Got some authoritative immunology less than a century old?  Maybe someone that knew about immunoglobulins?
 
:::"It can be asserted" and "just because there are other explanations" doesn't support similars, any more than the Illuminati ''might'' be responsible for all evil in international relations. "Might" isn't encyclopedic.
 
:::Actually, I prefer the wicker man to the straw man.
 
:::I'm disgusted, but I will not give up because the integrity of CZ means something to me. To stop responding to handwaving would be to give in to the stamina of homeopathic advocates.
 
:::You were the one that brought up various drugs. I added lithium carbonate as one example. How is it a straw man?  In therapeutic doses, it has no effect on non-hypomanic patients. Easy to call things straw men when you don't like them, and drop back to "it can be asserted." The capability of assertion does not make for encyclopedic quality. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:16, 14 September 2010 (UTC)
 
===Regarding 'point of view'===
 
No "point-of-view" disparagement required for conclusions/inferences drawn from science. Any such disparagement itself reflects "point-of-view". The lede as it reads now reflects medical science's judgment of homeopathy. Personally, as a scientist, I consider an open mind a virtue, but I try not to have it so open my skeptical inquirer falls out. [[User:Anthony.Sebastian|Anthony.Sebastian]] 03:16, 14 September 2010 (UTC)
 
:As I've suggested, we have to face the issue that the two advocates appear not to want the general judgment to appear, unless it is immediately accompanied by a Seinfeld-like "but that's OK, and homeopathy works." [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:25, 14 September 2010 (UTC)
 
== Biology-Health Sciences Editor ruling needed ==
 
Immunology clearly falls into these fields, ''not'' Healing Arts. I contend that it is ludicrous for this article to be using von Behring as a source of authority. It's fair enough to mention a 1901 Nobel Prize winner in a historic context, but a ruling is needed if his statements on homeopathy and immunotherapy can be used as substantiation for plausible modes of immune response.  Immunology has progressed a bit in over a century.
 
It's futile to argue this with Mr. Ullman, and I believe we have enough relevant Editors to settle this point. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 18:35, 14 September 2010 (UTC)
:Agreed (sorry for butting in). ([[User:Chunbum Park|Chunbum Park]] 09:56, 15 September 2010 (UTC))
::Don't feel sorry, Chunbum, your particpation and opinion is a valued part of the decision process.
::This appears to be a bigger issue than homeopathy.  It appears that you are asking to limit an editor on an article.  We don't have a mechanism for that.  We've really left that to the devices of other editors to challenge unusual statements by other editors.  I would expect that even Dana would appreciate a immunologist's input, but regardless, they'd both still need resources to cite. I'm not sure that a Health Sciences Editor can overrule a Healing Arts editor on an article, but he can certainly challenge anything that counters his beliefs. I would think the EC or EiC would have to rule on something like that.  Of course, that would be the Managing Editor should the new charter take effect. [[User:D. Matt Innis|D. Matt Innis]] 12:59, 15 September 2010 (UTC)
:::That's much what I was thinking. To take a parallel example relevant to Howard, the article on the [[Iraq War]] might, and in my view should, discuss the question of its legality. But I don't suppose the article is affiliated to the Law Workgroup. So what happens with a hypothetical conflict between, say, Howard and a law editor on that question? I think the new EC has to think about the whole system here, not just leave it to the ME to invent precedents. [[User:Peter Jackson|Peter Jackson]] 15:03, 15 September 2010 (UTC)
::::Perfect example, Peter.  The new charter should allow the new ME to make a decision on the fly based on ample input from everyone (especially editors) and then the EC can take its time to review the ME decision and either overrule it or support it.  Hopefully, that will develop a sort of "case law" that eventually develop into policy based on a democratically expert debated concepts rather than customary consensus. Meanwhile, authors will be able to move on to different content while the decision is reached elsewhere.  [[User:D. Matt Innis|D. Matt Innis]]
 
(undent) All of you make good points, but the specific may be a little easier. If I were to state the problem in EC terms, it is that different disciplines acquire knowledge at different rates. Were this, for example, a Literature article, Oscar Wilde or G. B. Shaw's comments would be relevant. If this were aviation engineering, however, I think it is relatively obvious that Orville and Wilbur Wright's commentary would not be very relevant to an Airbus (most recent model) or Boeing 787 Dreamliner. While I've often wondered how a classic military genius such as Belisarius would do with airmobile forces, he'd have a bit of catching up.
 
Von Behring, and indeed Hahnemann, were giants in their time. Today, however, von Behring wouldn't know how to find his way to the protein sequencer or the molecular visualization workstation.
 
The policy, therefore, might say that to cite an authority as more than a historic point, that authority has to be reasonably familiar with current concepts. It may be even faster now, but, a few years ago, based on MEDLINE growth, the amount of information in health sciences doubled every seven years. Some fields, such as molecular pharmacology, went from nonexistent to major disciplines.  There's not going to be a citation that "Von Behring is obsolete", but that's a reasonable inference.
 
Peter, I would be absolutely delighted to have an article on the legality of the Iraq War. The article is not now affiliated with law, or several other relevant workgroups, due to the three workgroup limit. In doing the main draft of these articles, I had quite enough to do with the "what" and "how" without getting into the just war theory or international law. I would be happy, over an appropriate beverage, to discuss what I personally consider to be vague language in the UN Charter. 
 
Unquestionably, Matt, workgroups need to be revised. I have been doing some experimentation with subgroups, but they are not a sole answer. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:19, 15 September 2010 (UTC)
 
: I think the word "ruling" in the section title is an error. Certainly ''comment'', or even ''contributions'', from those editors would be useful and (I assume) welcomed by all concerned, but I do not think they have the authority to ''rule'' here.
 
: The paragraph quoting von Behrig starts "Scientists and medical doctors today do not think that the principle of similars is generally true or useful, and they explain the efficacy of vaccination without referring to it. Physicians of the 19th century however did consider that the principle could be valuable." That strikes me as fair. Given that context-creating text, I see no objection to the von B quote.
 
: As I see it, there are serious issues with this article, and Howard is right about most of them. However, on this particular point, I see him as tilting at a windmill. [[User:Sandy Harris|Sandy Harris]] 02:52, 16 September 2010 (UTC)
 
:::One never knows...the windmills ''might'' be giants. Seriously, I really don't have a problem with historical quotes in historical contexts. Such contexts, though, would include both Osler's preference for 19th century homeopathy over 19th century allopathy, and his later statement that both allopathy (as used at the time) and homeopathy were both "cults" that needed to be replaced by scientific medicine.
 
:::Recent comments on this talk page, however:
:::<blockquote>Whether physicians today (or yesterday) refuse to believe that the "principle of similars" is utilized in medicine, it still can be asserted that they are consciously or subconsciously utilizing it. This is NOT to say that ALL drugs are prescribed by this principle (Howard creates a straw man argument with his reference to lithium carbonate). Further, just because there are other explanations for how or why Ritalin works does not take away the fact that the "similars" principle may also be at play. Dana Ullman 16:14, 14 September 2010 (UTC) </blockquote>
::: made me concerned that advocate(s) wanted to reintroduce the von B quote ''without'' the qualifiers, and suggesting that similars ''are'' the mechanism of medical immunization. That is not acceptable and is flatly wrong. I suspect that some of the molecular immunologists building acellular vaccines may never have heard of similars and certainly aren't designing with that principle, rather than protein structure-activity.
:::Lithium carbonate is hardly a straw man, as its activity would not be demonstrated in a proving on a non-hypomanic individual, only toxic effects in high doses.  When things demonstate exceptions to basic concepts such as similars and proving, they become significant negative data. "It can be asserted" is hardly encyclopedic, thinking of the classic assertion that if my aunt had testicles, she'd be my uncle.--[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:33, 17 September 2010 (UTC)
[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:26, 17 September 2010 (UTC)
 
== Followup on Anthony's comment about alternative medicine ==
 
While I agree with your addition, I wonder if it goes far enough. Complementary and alternative medicine, while often grouped together, are not the same. Alternative medicine, to use NCCAM's definition, is a ''substitute'' for conventional medicine, while complementary medicine can be [[integrative medicine|integrated]] with conventional medicine. Rather by definition, alternative medicine will not agree with conventional medicine, and never the twain shall meet.
 
It's not implausible that there ''could'' be complementary homeopathy, but I find it interesting that the article really doesn't address it. At best, there are arguments that homeopathy is superior to conventional methods for specific disorders. There's some hand-waving that conventional physicians use homeopathic remedies in their practice, but no discussion of the indications and rationale for doing so.  In other articles, there is discussion of the complemntary use of acupuncture, chiropractic, etc.
 
Whether or not homeopathy is CAM rather than AM, this article overwhelmingly treats it as AM. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 21:50, 14 September 2010 (UTC)
 
:Howard, I took a long rest from this article, and it seems that you would really benefit from doing so too.  I realize that by saying this you may now want to edit more often than ever.  My concern is that you are beginning to lash out at me and at this subject in an extremely emotional way. It seems that you are no longer trying to create an encyclopedic article but one that pushes your POV which remain inadequately informed about this subject of homeopathy.  Heck, even when Dr. J sought to reach out to Sandy and be friendly, rather than adverserial, Sandy told him that he wasn't interested.  That's OK too...and Dr. J didn't seek to connect personally.  Let's not make this effort by Dr. J to be as "bad" as you've tried to make it.  [[User:Dana Ullman|Dana Ullman]] 22:54, 14 September 2010 (UTC)
 
::Well, gee. I've been discovered: my whole motivation is attacking homeopathy, and I '''never, ever''' contribute to anything else at Citizendium.  Obviously, [[New Delhi metallo-beta-lactamase-1 enzyme]] is just an attack on homeopathy, as is [[CZ: Pacific War Subgroup]], as is (quite friendly) collaboration on [[opportunistic encryption]].
 
::Why is this in a subsection where I was addressing the complementary and alternative aspects of homeopathy? That was hardly emotional. I neither need nor want your advice or concern on what I should do.
 
::It ''is'' adversarial. Deal with it. Mortality & Morbidity conferences, military After-Action Reviews, engineering design reviews, etc., benefit from an adversarial approach.
 
::As far as I can tell, your definition of "adequately informed" is to accept homeopathy. The Ormus article hurt Citizendium, and I am convinced that homeopathy does as well.  I do know that I have had people refuse to join CZ specifically due to the homeopathy article. I'll believe you want to be encyclopedic when I see you contribute to things other than a single issue.
 
::If I get extremely emotional about something, I tend to be more quiet, and perhaps smile a lot. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 23:07, 14 September 2010 (UTC)
 
== Encyclopedia Britannica Online: Homeopathy lede ==
 
Possibly of interest:
 
"Homeopathy"
 
"a system of therapeutics, notably popular in the 19th century, which was founded on the stated principle that “like cures like,” similia similibus curantur, and which prescribed for patients drugs or other treatments that would produce in healthy persons symptoms of the diseases being treated."
 
"This system of therapeutics based upon the “law of similars” was introduced in 1796 by the German physician Samuel Hahnemann. He claimed that a large dose of quinine, which had been widely used for the successful treatment of malaria, produced in him effects similar to the symptoms of malaria patients. He thus concluded that all diseases were best treated by drugs that produced in healthy persons effects similar to the symptoms of those diseases. He also undertook experiments with a variety of drugs in an effort to prove this. Hahnemann believed that large doses of drugs aggravate illness and that the efficacy of medicines thus increases with dilution. Accordingly, most homeopathists believed in the action of minute doses of medicine."
 
"To many patients and some physicians, homeopathy was a mild, welcome alternative to bleeding, purging, polypharmacy, and other heavy-handed therapies of the day. In the 20th century, however, homeopathy has been viewed with little favour and has been criticized for focusing on the symptoms rather than on the underlying causes of disease. Homeopathy still has some adherents, and there are a number of national and international societies, including the International Homoeopathic Medical League, headquartered in Bloemendaal, Neth."
 
http://www.britannica.com/EBchecked/topic/270182/homeopathy
 
[[User:Anthony.Sebastian|Anthony.Sebastian]] 03:27, 16 September 2010 (UTC)
 
:The first two paragraphs, I hope, are not controversial. The talk page controversy, however, has significantly involved both homeopathic attempts to claim medical logic, as well as a broader assumption, by the homeopathy advocates, that homeopathy needs to be regarded as having equal credibility to conventional medicine.  Attempts to claim that the principle of similars is the underlying mechanism for medical treatments developed, or validated, using methods of molecular pharmacology fall under my first point. Closely coupled is the homeopathic argument that homeopathy mimics body defenses manifested as symptoms, when the actual defense is quite different than the symptom producing factor -- tetanus is a good example, where the defenses are immunoglobins that have no particular symptom-producing quality, but the symptoms of  spasticity and convulsions are caused ("indirectly") by the exotoxin of ''[[Clostridium tetani]]'' and can be lethal. The defenses neutralize the toxin, and, coupled with antibiotics and surgery, eradicate the source of the toxin.
 
:In other words, there's a refutation of molecular medical arguments, but no molecular explanation of how similars affect the body. Hand-waving about memory of water isn't on the same level as immune reactions that can be demonstrated ''in vitro'' and ''in vivo'', or structure-activity interactions with cellular receptors. --[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 23:12, 16 September 2010 (UTC)
 
== "Alternative Medicine and the Laws of Physics" ==
 
Of possible interest:
 
Alternative Medicine and the Laws of Physics
 
Robert L. Park
 
''Skeptical Inquirer'', Volume 21.5, September / October 1997
 
http://www.csicop.org/si/show/alternative_medicine_and_the_laws_of_physics/
 
[[User:Anthony.Sebastian|Anthony.Sebastian]] 03:59, 16 September 2010 (UTC)
:Having read the article I feel a neutral way of presenting homeopathy would be something like "it is a type of medicine supported by neither scientific reasoning nor data. that being said this is what homeopaths think: 1, 2, 3." ([[User:Chunbum Park|Chunbum Park]] 05:40, 16 September 2010 (UTC))
 
:: I think that overstates the case. Homeopathy is based on a system that includes reasoning which is at least pseudo-scientific. There is data, though much of it is of dubious quality; in particular, "data" is not the plural of "anecdote". I don't think your text above is neutral in any sense I'd recognise.
 
:: The current draft includes "the consensus of medical and scientific opinion is that homeopathy is unfounded." I think that is accurate, neutrally stated, and sufficiently direct.
 
:: That said, I do think we should link to highly critical articles such as that one, possibly the [http://rationalwiki.org/wiki/Homeopathy rational wiki] page, and certainly the [http://xkcd.com/765/ lovely cartoon] they use. [[User:Sandy Harris|Sandy Harris]] 07:40, 16 September 2010 (UTC)
 
::: See rational wiki's article "Citizendium" first. [[User:Anthony.Sebastian|Anthony.Sebastian]] 03:57, 17 September 2010 (UTC)
 
== Suggest ending Main Article draft at end of lede ==
 
Let reader use Biblio to get further information. Concentrate on thorough Biblio subpage. 06:39, 17 September 2010 (UTC)
 
: I don't think that is an adequate approach for an encyclopedia. We want a reasonably detailed explanation here. That said, the article could likely be shortened significantly without losing anything valuable. [[User:Sandy Harris|Sandy Harris]] 12:14, 17 September 2010 (UTC)
 
::At home much resource cost that could be going into even copy edit of other articles, articles that deal with topics that are likely to have more serious users? I'd wager that a good part of the hit count on this article is due to people at other wikis looking for controversy.
 
::That being said, I'm not sure how feasible it is under present policy. Assume three Health Sciences and Biology Editors are willing to nominate the truncated approach for Approval. Healing Arts Editors say it is not Approvable.  It would be one thing for a Mathematics Editor to question approval for a cryptographic topic written by a computers person, but we've gotten through effective collaboration among, say, Computers, Mathematics, and Military. Health Sciences and Healing Arts, among the workgroups, are the only case where we have different workgroups for fundamentally different views on the same subject area. It's a bug, not a feature; we don't have separate-but-equal Religion and Atheism workgroups. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 15:53, 17 September 2010 (UTC)
 
== Definition ==
 
The current definition reads "System of alternative medicine that asserts — contrary to scientific  evidence — that substances known to cause specific syndromes of symptoms can also, in very low and specially prepared doses, help to cure people who are ill with a similar syndrome of symptoms." I think that is a moderately awful definition. The problems I see are:
: The "contrary to scientific evidence" bit, or similar text, has been added at least twice and reverted at least once. I don't think it belongs in the definition.
: "syndrome of symptoms" is used twice. That's ghastly stylistically, "syndrome" is a technical medical term that may not belong here, and in any case, I suspect "syndrome of symptoms" is redundant. What else could you have a syndrome of? Or does a syndrome include more than just symptoms?
My version would be: A system of alternate medicine based on the idea that substances known to cause particular combinations of symptoms can, in very low and specially prepared doses, help to cure people who are ill with similar symptoms.
(sig added later [[User:Sandy Harris|Sandy Harris]] 23:14, 17 September 2010 (UTC))
 
""Syndrome of sympoms", indeed, is ghastly. Unfortunately, it touches on a difference between homeopathic and current medical thinking that is as important as similars. Modern physicians look first for an etiological diagnosis: what is the cause of the patient's distress? (Note here that "symptom" is being used in a lay sense here -- there are differences of theory as well).  Homeopaths consider that the "disease model", not patient-centric, and often reject a causality-based approach. Their focus is on the products of the cause (in medical thinking) or the body wisdom expressing its defenses.
 
:A better wording would be welcome, but the rejection of etiologic thinking, and the focus on similars as a means of reducing symptoms, is fundamental. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 15:53, 17 September 2010 (UTC)
 
Sandy's version:
*A system of alternate medicine based on the idea that substances known to cause particular combinations of symptoms can, in very low and specially prepared doses, help to cure people who are ill with similar symptoms.
 
 
My understanding:
*A system of alternate medicine based on the idea that large dosages of substances known to cause particular combinations of symptoms in healthy individuals can, in very low and specially prepared doses, help to cure a person whose illness causes similar symptoms.
[[User:D. Matt Innis|D. Matt Innis]] 21:49, 17 September 2010 (UTC)
 
::I  am quite willing to be corrected here, but I think the idea of an illness that creates similar symptoms is still too close to an etiologic model of disease to be accepted by homeopaths. While I don't have better words, my sense is they would say the symptoms are produced by the "wisdom of the body" as "defenses" and the remedies strengthen the defenses. --[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 23:59, 17 September 2010 (UTC)
 
 
::: That could be the next sentence.
 
 
:::*A system of alternate medicine based on the idea that large dosages of substances known to cause particular combinations of symptoms in healthy individuals can, in very low and specially prepared doses, help to cure a person whose illness causes similar symptoms.  In essence, they believe that symptoms are produced by the "wisdom of the body" as "defenses" and homeopathic remedies are designed to strengthen those defenses.
 
:::[[User:D. Matt Innis|D. Matt Innis]] 03:22, 18 September 2010 (UTC)
 
::::Add: They do not use the disease model of conventional medicine, in which there is a disease rather than an individual set of symptoms, and treatment directed at a cause of that disease as it presents in multiple patients. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 03:29, 18 September 2010 (UTC)
:::::More work:
:::::*This contrasts with conventional medicine's "disease model" of treatment that looks to treat the disease process and therefore relieve the symptoms.
:::::I'm not sure that's totally true, though.  Many conventional treatments are directed at relieving symptoms, too.
:::::[[User:D. Matt Innis|D. Matt Innis]] 03:54, 18 September 2010 (UTC)
 
(edit conflict) (undent)
There's a different philosophy in symptomatic treatment. If I sprained my ankle badly enough to need surgical repair, the cause would be relevant to a conventional orthopedist who needs to work on the damaged structures. Otherwise, the exact ligament stretch might be known, but it's not of therapeutic benefit. Symptomatic pain relief is the first consideration -- yes, rehabilitation may focus on exact etiology, but, for the sake of argument, assume it's self-limiting.
 
Sometimes, as with uncomplicated childhood otitis media, even if it is bacterial, antibiotic therapy may not be justified. Presumably, though, the child can still get acetaminophen.
 
In both of the cases above, there was awareness of an etiology, but a choice to treat only symptoms. Palliative care is often largely but not exclusively symptomatic -- still, an etiology would be necessary for chemotherapy or radiotherapy to slow the growth of an incurable tumor.  Pain management, though, is symptomatic and even more important. Where does nursing care fit?
 
The homeopaths, however, appear to exclude the idea of treatment based on etiology, as opposed to symptom relief when the cause is either self-limiting or not treatable. I spend hours daily giving comfort care to my cat buddy, relatively little of which is directed at the cancer itself, but much more in nutrition, emotional support and wound care. Indeed, I am using some complementary medicine along with a lot more conventional things.  Homeopathic ideas of symptom-oriented remedies don't enter into it. --[[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:28, 18 September 2010 (UTC)
 
: I don't think either that long definitions are a good idea in general, or that the proposed "next sentences" are needed in this definition. In the article, certainly; in the lede, probably. However, the definition needs to be short and direct. In particular, it needs to be short enough to look reasonable when cited on a related articles page. [[User:Sandy Harris|Sandy Harris]] 04:46, 18 September 2010 (UTC)
 
::If the definition is to be short, then, I believe the rejection of etiology is far, far more significant to homeopathy than the better-known issues of small doses. It appears to me that Hahnemann's insight dealt with symptoms being the essential manifestation of health or not-health, and only ''then'' did he go to the idea of provings and similars. My understanding is that his using provings for malaria had to do with the symptom production of quinine.
 
:::Absolutely, I forgot that we were working on the definition!  You're right, Sandy. [[User:D. Matt Innis|D. Matt Innis]] 21:27, 18 September 2010 (UTC)
 
::I believe there's a comment on this page, from a homeopath, that homeopathic remedies are not always administered in homeopathic femtodoses.
 
::The rejection of etiology  is also key to much of the dispute with medicine, as I mentioned in terms of clinical trials. It is also, however, central to the medical rejection of some homeopathic approaches, such as the principal treatment for malaria being based on reducing ''Plasmodium'' parasites in the blood. Quinine remains a third-line drug for malaria, but its action in reducing fever and chills is due to its ability to suppress the parasites, not (in a medical view) what effects are caused by high doses of quinine. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:56, 18 September 2010 (UTC)
:::Quinine remains a third-line drug for malaria, but its action in reducing fever and chills is due to its ability to suppress the parasites, not (in a medical view) what effects are caused by high doses of quinine.
 
::::I think that's the point; it's not that homeopath's don't care about etiology, they just don't concern themselves with it.  If it causes the same symptoms in a normal person, then it's used to treat the person that has those same symptoms, regardless of the cause. As you say, they might contend that the plasmodium is not what causes the symptoms, rather the symptoms are the body's response to plasmodium. To them it doesn't matter. [[User:D. Matt Innis|D. Matt Innis]] 21:28, 18 September 2010 (UTC)
 
:::::As my grandmother might have said, ah-HAH! Admittedly, I'm taking the example of the worst form of malaria, but a patient presenting with the cerebral form of ''[[Plasmodium falciparum]]'' malaria may well die in 18 hours. In general, the standard of medical care would be [[artemisinin|artemisinin-based combination therapy]], with [[critical care]] support for effects such as  [[acute respiratory distress syndrome]] or [[disseminated intravascular coagulation]].
 
:::::Quinine, in substantial doses and '''in combination with''' doxycycline, tetracycline, or clindamycin, be lifesaving. If I were the patient, however, and someone offered me homeopathic oral doses of oral quinine, I'd prefer a lethal dose of barbiturates, or a large-caliber bullet to the back of the neck (messy but fast).
 
:::::Now, I'd have every respect for a ''complementary'' homeopath that suspected severe falciparum malaria, and immediately transferred the patient to medical care. Assuming such care were available, I'd regard an ''alternative'' practitioner as having, as the lawyers put it, ''depraved indifference for human life.''. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 22:02, 18 September 2010 (UTC)
:::::: I suspect the cerebral form would have different symptoms, therefore different remedies as well. A bullet is probably not one of them. ;-) [[User:D. Matt Innis|D. Matt Innis]] 23:40, 19 September 2010 (UTC)
 
:::::::Are you doubting the efficacy of a .45 caliber ACP 254-grain round, which is lead in a hardly homeopathic dose?  Nevertheless, if I had cerebral P. falciparum malaria, I know that active medical treatment is still very iffy. Seriously, we have the problem of any validation here; I cannot imagine an ethics review board that would approve any treatment for such a life-threatening disease without overwhelming laboratory evidence for the control arm. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 22:21, 20 September 2010 (UTC)
 
===Sandy's edit to the definition===
...specifically "help to cure or prevent  illnesses involving similar symptoms."  While a homeopath will have to review this, I don't think "illnesses involving similar symptoms" is really a homeopathic concept. They certainly object to "diseases with similar symptoms", and tend to reject "disease" as a medical conceit. The symptoms are signals of the body's defenses to be strengthened, not the effects of a causative factor. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 04:59, 18 September 2010 (UTC)
 
:I think you're splitting hairs, but, yes, let's hear from a homeopath on this. [[User:D. Matt Innis|D. Matt Innis]] 21:27, 18 September 2010 (UTC)
 
:Sandy's new definition is definitely an improvement. [[User:D. Matt Innis|D. Matt Innis]] 21:32, 18 September 2010 (UTC)
 
::Li'l hard pressed for time. I'm happy with Alexander's definition, but if you guys feel it needs to be simpler, I have a 'simpler definition', which would read:-<blockquote>(Homeopathy is) an alternative system of medicine, which stimulates the natural healing processes of the body (with the help of sub-physiological doses of a remedy, by using its rebound effect), to restore health (homeostasis) in a sick person.</blockquote>
:::The matter in brackets is optional.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 07:36, 19 September 2010 (UTC)
:::Note that it is '''alternative medicine''' and not '''alternate medicine'''.&mdash;[[User:Ramanand Jhingade|Ramanand Jhingade]] 07:44, 19 September 2010 (UTC)
 
::::Unfortunately, "rebound effect" is not a well-defined term, certainly in medicine, so should not be used in a definition unless it is well defined in an article of its own.  The alternate definition depends heavily on homeopathic terminology, such as "natural healing processes", as well as using homeostasis is far broader a context than is used in the biological sciences -- to say nothing amout emerging concepts such as [[allostasis]].
 
::::The proposed new definition also overemphasizes the aspect of small doses and does not address the apparent rejection, by homeopathy, of the idea of "disease". Instead, it speaks of "restoring health", without addressing the  meaning of the state of non-health.
 
:::Please confirm or correct the statement that homeopaths do not believe in the concept of disease, in the sense that disease has an etiologic cause and the cause needs to be corrected. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 08:30, 19 September 2010 (UTC)
 
::::I agree with Howard here, Ramanand, that your version introduces too many vague terms to be considered for use as a one sentence definition. [[User:D. Matt Innis|D. Matt Innis]] 23:44, 19 September 2010 (UTC)
 
What about <blockquote>A system of alternative medicine based on the idea of stimulating the body's natural healing processes by administering tiny doses of substances which, when given in large doses to healthy individuals, cause similar combinations of symptoms.</blockquote> I agree that Ramanand's definition has some problems, and I think the full version is too long, but it seems to me the point about stimulating natural defenses is central. [[User:Sandy Harris|Sandy Harris]] 03:07, 20 September 2010 (UTC)

Latest revision as of 16:21, 20 September 2010

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APPROVED Version 1.1

The Approval includes two copyedits [1] Hayford Peirce 19:13, 11 October 2009 (UTC)

I'm not sure how to add yet another archive and get things to show up properly in the header here. Could someone do so? Howard C. Berkowitz 19:22, 11 October 2009 (UTC)

Beginning with semi-lower-case editorial...

As a first step, I'm going to all footnotes that contain other than bibliographic material or definitions, and either moving the substantive text into the main article, or, in some cases, linking to a subarticle.

While it may be reasonable, in a printed book or journal, to have bottom-of-the-page notes, in this format, the content of the notes will not be seen unless the reader clicks on them. How many readers do that? In effect, the text is being hidden. Howard C. Berkowitz 19:37, 11 October 2009 (UTC)

A balanced blog post on the subject

can be found here. --Daniel Mietchen 09:21, 16 December 2009 (UTC)

I added a comment, as did Paul. Truly delightful, however, is

Personally, I would really like to see a homeopathic treatment for dehydration. You'd have to have a compound that causes dehydration, but what would you dilute it in? you can't dilute it in water or saline, because those will rehydrate, and in homeopathy, you have to CAUSE dehydration to cure it...but you can't having anything that CAUSES dehydration because it would have to be diluted to the point where none of the dehydrating agent remains...

It should be noted that some camping supply stores, in the same aisle as freeze-dried foods, offer cans of "dehydrated water". Ethical staff makes sure that new users understand the purpose of same. Howard C. Berkowitz 15:06, 16 December 2009 (UTC)


Howard, you gave the wrong link for Sympathetic magic. It's http://en.citizendium.org/wiki/Sympathetic_magic And make sure the period at the end does not get connected to the link. Chris Day 15:26, 16 December 2009 (UTC)

That's a reasonable way to look at it, which is unusual for a blog. D. Matt Innis 18:43, 16 December 2009 (UTC)

Put it into the External Links. --Daniel Mietchen 19:27, 16 December 2009 (UTC)

Ramanand's changes

First, the word " most biased medical " is argumentative, does not fit the language of the lede, and is clearly advocacy.

The statement supporting homeopathy in the lede, even if the references were solid, belongs, stylistically, in a later section on the mechanisms of homeopathy. One reference is, as far as I can tell, from a Brazilian university with a site in, presumably, Portuguese, which I do not read. We generally don't use non-English references, especially when they are not clearly from peer-reviewed journals or otherwise reviewed sources.

The other reference is from Khuda-Bukhsh, whom, I believe, has been in the memory of water controversy, is a review of possible molecular mechanisms of action. On first glance, it's an interesting paper, but does not talk at all about efficacy — just how homeopathic remedies may work, if they work. It doesn't belong in the lede, although it's not unreasonable to use it as a reference in a later section.

Neither addition works where it is. The first is advocacy and non-neutral. --Howard C. Berkowitz 17:45, 7 January 2010 (UTC)

The use of "biased" is definitely adversarial. Chris Day 21:12, 7 January 2010 (UTC)
With regard to the rebuttal (it works, and we know how), I am loath to see this article head down the direction of he says, she says tit for tat. Chris Day 21:21, 7 January 2010 (UTC)
The whole article is full of oxymorons, containng both viewpoints, so I don't see anything wrong with what I've inserted, unless the critics' statement is also removed (about what scientists feel). I'm fine if the word biased is removed, if it seems adversarial. The Portuguese and French is only in the references section and shouldn't be a problem.—Ramanand Jhingade 10:28, 8 January 2010 (UTC)
Well, Ramanand, the general CZ, policy, especially in the Charter, is that articles don't equally present all views. They present the preponderance of the expert views, and, in this case, the experts are in health sciences; there isn't a unifying discipline among healing arts. Not all healing arts support homeopathy.
Everyone needs to Neutrally present all views. D. Matt Innis 02:31, 9 January 2010 (UTC)
The foreign language citations have been a problem in many other articles, not just here.
I think you mean contradictions or rather or challenges, not oxymorons. An oxymoron would be a "heroically large dose of a homeopathic simillum." An oxymoron is a contradiction in terms.
Sorry, I'm in favor of removing both additions. You will need to face the reality that the article will not be as pro-homeopathy as you want, just as others wish it weren't here at all. It's a compromise. --Howard C. Berkowitz 15:48, 8 January 2010 (UTC)
I applaud, encourage and appreciate collaborative efforts to work toward improvements, but I think this lead still needs significant work to add any substantial improvement to the approved version's lead. D. Matt Innis 02:28, 9 January 2010 (UTC)
I forgot to wish all of you a Happy (belated) New Year. The presently approved article's Lead isn't 'neutal' at the moment. It should either explain homeopathy plainly or if y'all want criticism in the Lead, it should contain both viewpoints. Where's Dana, by the way, in Germany again?—Ramanand Jhingade 09:14, 9 January 2010 (UTC)
Happy New Year to you, too! Please let me know where you think the present Approved version lead (as opposed to the draft lead) is lacking and I'll be glad to take a look. Dana approved the current lead, too, but I'm sure he'd take a look if we asked him. D. Matt Innis 15:00, 9 January 2010 (UTC)
I'd posted a whole lot of links to homeopathic articles, late last year, but did not have the time to add it in the article. I was expecting someone here to do it, but no one did (not even Dana)! I already wrote what I wanted above, "It should either explain homeopathy plainly (without criticism in the very 1st sentence) or if y'all want criticism in the Lead, it should contain both viewpoints."—Ramanand Jhingade 08:34, 12 January 2010 (UTC)
We certainly can't add every link ever written to this article. This is the overview article in an encyclopedia type format and summarizes homeopathy pretty well, I think. Again, don't confuse the lead in the Draft with the lead in the main Homeopathy article. I agree the lead in the draft needs more work and is not an improvement in its current form. D. Matt Innis 12:45, 12 January 2010 (UTC)
If nothing else, bibliographic links not directly related to the text belong on the bibliography page, preferably in articles. Also, in other articles, there is some selectivity. In some cases, reviews are more appropriate than small primary studies. In other cases, peer review and responsible publications are appropriate. In yet other cases, there is more leeway on publications but the reason needs to be explained.
It's not necessarily reasonable to assume someone else will edit and add articles with which they aren't familiar, or with which they might disagree.
What principles of homeopathy are in not in the lead? It should go without saying that homeopathists believe what they are doing, or the article wouldn't be here at all. Having a small number of dissenting comments from people who question hematology simply establish it isn't universally accepted, and the details and pros and cons should be in the article, but later. Howard C. Berkowitz 13:27, 12 January 2010 (UTC)
RE: provided references from Ramanand, this must be the list and I do remember it, but it's mostly primary research. They could be used for a more detailed article to support a specific claim where reviews aren't available, but to cite them here would result in too much detail for the general nature of this article. Primary research doesn't belong in a bibliography either. I'm not sure that we have a subpage that would be appropriate for primary research, though it's an interesting idea for some other project, or way in the future for this one. Otherwise, I'd think it would be a problem with CZ:Maintainability. There are other sites that do list all the research for each particular subject. D. Matt Innis 14:51, 12 January 2010 (UTC)
This is one page (Homeopathy/Trials) that exists with a tabulated summary of some of the voluminous primary literature. I agree maintainability is an issue. I bet there are hundreds of articles like this and the main problem is reducing it to the most important articles in the field. If that could be done well it might make a good catalog. Chris Day 17:18, 12 January 2010 (UTC)
Matt, I made some time to read the entire (presently) approved article. I don't see any sentence saying there is evidence for homeopathy (the feg pdf document I've inserted in the present draft is accepted by 'mainstream' scientists as well). I object to the term 'placebo' in the lead (Edzard Ernst is known to be a ridiculed homeopathic baiter in the U.K.). I also object to the term 'fraud' in the Overview section

They also are interested in whether positive results against expectation sometimes reflect manipulation of data or perhaps even fraud.

. Like you said, can we edit the (presently) approved article?—Ramanand Jhingade 17:34, 23 January 2010 (UTC)
David (Ellis), can you please tell me what objections you have to the feg pdf document?—Ramanand Jhingade 17:42, 23 January 2010 (UTC)

(undent) Placebo in the lead is perfectly appropriate; conventional medicine routinely accepts the placebo effect as a component of therapies.

Fraud is mentioned gently as a possibility by some observers, seemingly far more gently than some of the homeopathic claims of the danger of medicine. Sorry, it's not unbalanced. Please do not go to "known" homeopathic baiters anywhere, else that you start having people bring in medical baiters from homeopathy. The problem with bait is that it often has a hook inside.

By edit the presently approved article, no, other than for typos, it's frozen. It is possible to edit the draft, and eventually to have the edited draft become the newly approved.

Again, what specific principles of homeopathy 'are not in the lede? --Howard C. Berkowitz 18:03, 23 January 2010 (UTC)

Friends, it has been a while since I check-in here. I have not re-read most of the new draft, but I can tell you that I do not like the lede paragraph. It is simply not encyclopedic or impartial. Anyway, we only recently spent a lot of time approving the previous edition. I suggest that we let it sit for 3-6 months or more before we re-do it. Dana Ullman 05:28, 1 February 2010 (UTC)
Dana, I hope you can insert sentences that read something like, "there is scientific evidence for homeopathy", using the PDF for "Scientific framework of homeopathy: evidence-based homeopathy" available at http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewFile/286/354 wherever appropriate.—Ramanand Jhingade 08:21, 2 March 2010 (UTC)

British House of Commons Science and Technology Committee report

The committee commissioned by the British government has reassessed homeopathy as a treatment option under the national health service. It's enquiry sought written evidence and submissions from concerned parties (See News in brief: Homeopathic assessment and Evidence check: Homeopathy). Both sides of the debate were represented and presented written evidence to the committee. In addition there were oral presentations from the following individuals:

  • Mr Mike O'Brien QC MP, Minister for Health Services, Department of Health;
  • Professor David Harper CBE, Director General, Health Improvement and Protection, and Chief Scientist, Department of Health;
  • Professor Kent Woods, Chief Executive, Medicines and Healthcare Products Regulatory Agency
  • Professor Jayne Lawrence, Chief Scientific Adviser, Royal Pharmaceutical Society of Great Britain;
  • Robert Wilson, Chairman, British Association of Homeopathic Manufacturers;
  • Paul Bennett, Professional Standards Director, Boots;
  • Tracey Brown, Managing Director, Sense About Science;
  • Dr Ben Goldacre, Journalist.
  • Dr Peter Fisher, Director of Research, Royal London Homeopathic Hospital;
  • Professor Edzard Ernst, Director, Complementary Medicine Group, Peninsula Medical School;
  • Dr James Thallon, Medical Director, NHS West Kent;
  • Dr Robert Mathie, Research Development Adviser, British Homeopathic Association.

A summary statement from the House of Commons Science and Technology Committee was released with the report in Feb 2010:

... the NHS should cease funding homeopathy. It also concludes that the Medicines and Healthcare products Regulatory Agency (MHRA) should not allow homeopathic product labels to make medical claims without evidence of efficacy. As they are not medicines, homeopathic products should no longer be licensed by the MHRA.

The Committee concurred with the Government that the evidence base shows that homeopathy is not efficacious (that is, it does not work beyond the placebo effect) and that explanations for why homeopathy would work are scientifically implausible.

The Committee concluded - given that the existing scientific literature showed no good evidence of efficacy - that further clinical trials of homeopathy could not be justified.

In the Committee’s view, homeopathy is a placebo treatment and the Government should have a policy on prescribing placebos. The Government is reluctant to address the appropriateness and ethics of prescribing placebos to patients, which usually relies on some degree of patient deception. Prescribing of placebos is not consistent with informed patient choice-which the Government claims is very important-as it means patients do not have all the information needed to make choice meaningful.

Beyond ethical issues and the integrity of the doctor-patient relationship, prescribing pure placebos is bad medicine. Their effect is unreliable and unpredictable and cannot form the sole basis of any treatment on the NHS.
Source: UK Parliamentary Committee Science and Technology Committee - "Evidence Check 2: Homeopathy"

From the full report the committee also stated:

We conclude that placebos should not be routinely prescribed on the NHS. The funding of homeopathic hospitals — hospitals that specialise in the administration of placebos — should not continue, and NHS doctors should not refer patients to homeopaths.
Source: Evidence Check 2: Homeopathy, Fourth Report of Session 2009–10, House of Commons Science and Technology Committee, 20 October 2009, parliament.uk

In conclusion the chairman of the committee said:

This was a challenging inquiry which provoked strong reactions. We were seeking to determine whether the Government's policies on homeopathy are evidence based on current evidence. They are not.

It sets an unfortunate precedent for the Department of Health to consider that the existence of a community which believes that homeopathy works is 'evidence' enough to continue spending public money on it. This also sends out a confused message, and has potentially harmful consequences. We await the Government's response to our report with interest.
Source: UK Parliamentary Committee Science and Technology Committee - "Evidence Check 2: Homeopathy"

The Evidence Check definitely needs to be in the article. It has been hilarious watching the homeopaths squirming around trying to explain it away by butchering the quote from Cucherat's systematic review. It is like those reviews you see on movie posters where it says something like "Tremendous, Exciting (Evening Standard)" and then you go and look and see what the Evening Standard actually say and it is "A tremendous waste of time and money, has difficulty exciting all but the clinically insane". –Tom Morris 15:12, 3 March 2010 (UTC)
For some reason, I couldn't access Citizendium yesterday at this time. Meanwhile, I got a reply from Dr Peter Fisher to my e-mail in which he says that the individual specific rules of Homeopathy were not followed in prescribing/administering the Homeopathic remedy, so I hope good sense prevails over the 'UK Parliamentary Committee Science and Technology Committee'.—Ramanand Jhingade 13:43, 12 March 2010 (UTC)
With regard to "the individual specific rules of Homeopathy were not followed in prescribing/administering the Homeopathic remedy" what is Peter Fisher referring to? How does that impact the report? Chris Day 16:25, 12 March 2010 (UTC)
As I understand it, the individual specific rules of homeopathy mean that every patient is unique and the remedies appropriate for one will not be appropriate for another. Let's assume this is exactly correct. That would make classic randomized clinical trials, in which there is a standard treatment arm and a control arm, inappropriate, because there is no homeopathic standard.
A very similar problem, however, applies to highly individualized pharmacogenomic therapies: within a cohort of patients with, say, metastatic breast adenocarcinoma, the experimental hypothesis may be that a given treatment is applicable only to those patients with a specific BRCA gene coding. Panaceamycin is only expected to be effective in patients with that characteristic, and the others should get an aromatase inhibitor, the standard of care. Given there is a treatment, a placebo control is ethically unacceptable.
RCT's have been designed that still have statistical power, but are testing the diagnostic and treatment model, not panaceamycin. The clinician selects the treatment and sends an order to the pharmacy, where the pharmacist opens the next blind assignment envelope. If the patient is assigned to the experimental arm, the IV drug unit sent back to the care unit has panaceamycin in it if the genomic model calls for it, and the control treatment if not. If the patient is assigned to control, she gets control. It is the decision to assign that is being tested, more than the drug itself.
In like manner, homeopaths could prescribe a totally individualized remedy, but they would be blinded to whether or not the patient gets the remedy -- control could be placebo, or a medical treatment. With a sufficiently large sample, if the homeopathic model is correct, the patients receiving the remedy should do better.
It is not clear that homeopaths are willing to be tested in such a manner, which should obviate the argument about individualization not being permitted. --Howard C. Berkowitz 17:05, 12 March 2010 (UTC)
Brings me back to a question that I have never seen an answer to. How can remedies be mass marketed and sold off the shelf at places like wal-mart and whole foods and be so effective (as claimed)? These remedies are either robust or need to be highly individualized. If the latter, I don't see how how a mass market product will work. If the former, then they have indeed being found wanting (no better than placebo). Their defense against accepting the failed results of clinical trials precludes claiming successes from the mass market products. Which is it? Chris Day 19:15, 12 March 2010 (UTC)
A question, Chris, that I've asked myself. Let me respond indirectly. One of the major mass-marketed products is Oscillococcinum, about which I did write an article. What is the sound that is made by the creature from which the simillium is obtained? --Howard C. Berkowitz 19:28, 12 March 2010 (UTC)
Given that they are a £1.5bn industry we can expect to hear a lot of noise like that in the next few months. Chris Day 19:40, 12 March 2010 (UTC)
Howard, you got it right - for example, Ipecacuanha can't be given where Antim. Tart is indicated. Chris, classical homeopaths don't accept 'over the counter'/'off the shelf' products because anything between 2 to 20 remedies are mixed in one 'combination' (Hahnemann used to call such homeopaths the 'mongrel sect'), but since it's popular, the classical homeopaths can't do much about it. In India, homeopathy is a half a Billion $ 'industry' - and that is only counting the medicines sold 'over the counter' and not what is spent on homeopathic doctors - so we're not gonna let people talk rubbish about it. It really works (See the 'feg' pdf document I've posted in the previous section)!—Ramanand Jhingade 09:22, 13 March 2010 (UTC)

Ramanand, you didn't get right the essence of what I was saying: there are statistically powerful testing methods, which have been developed for biological therapies that indeed are individualized, which could answer the homeopathic objection to more traditional randomized clinical trials. I have not seen any evidence that homeopaths are willing to use such methods, but instead continue to insist on either statistically weak retrospective analyses or anecdotal/testimonial evidence. Howard C. Berkowitz 16:21, 13 March 2010 (UTC)

Howard, it is very simple: the homeopaths are perfectly happy to use clinical evidence when it shows that homeopathy works. But when it shows that it doesn't work, then the clinical trial methodology must be at fault! Heads I win, tails you lose. If clinical trials are unable to detect the effects of homeopathy, why is the British Homeopathic Association quote-mining Cucherat? What seems more likely: that homeopathy works but not to the point where the clinical trial can detect it, or homeopaths cynically misuse evidence to support their pre-ordained conclusions? It has been so amusing to watch: our politicians have seen that the King alternative therapist is actually nude. All the homeopaths have been able to do is spin, quote-mine and clutch at straws. –Tom Morris 18:38, 13 March 2010 (UTC)
I suppose there isn't really anything to do about it until there's a new Editorial Council and a reevaluation of workgroups. Howard C. Berkowitz 19:04, 13 March 2010 (UTC)
The draft is open to rewrite and, while I can't speak for everyone, I'll be glad to look at anything that gets put in it. I agree with Russell. D. Matt Innis 03:17, 14 March 2010 (UTC)
Howard, there is a lot of research going on in Homeopathy. Dr.Peter Fisher heads a research group in London and Dr.Rastogi heads a research group in India. I will email them about your suggestion. Tom, please look at the 'feg' .pdf document I posted - it is good, solid evidence that Homeopathy works!—Ramanand Jhingade 11:44, 14 March 2010 (UTC)

Friends...in due respect, anyone who takes this "report" seriously has an axe to grind or is simply under-informed.

Any rational person should and must be very suspicious of this "report." The MPs (Members of Parliament) who were a part of the Science and Technology Committee which voted for this anti-homeopathy report comprised of five members, with three members barely eking out their victory. Of the three votes, two members did not attend any of the investigational meetings, one of whom was such a new member of the committee that he wasn't even a member of the committee during the hearings, and the remaining "yes" vote was from Evan Harris, a medical doctor and devout antagonist to homeopathy. This report was not exactly a vote of and for the people. This information alone should entirely discount this "report" as a kangeroo court report that deserves that round circular file.

The very limited number of people who represented homeopathy were primarily three people. The others were entirely antagonistic to homeopathy or simply uninformed about it (such as the rep from Boots).

Despite the use and acceptance of homeopathy throughout the U.K., there is a very active group of skeptics, with significant Big Pharma funding, who work vigorously to attack this system of natural medicine. Even though there is a wide variety of serious and significant pressing issues in British medicine and science today, an active group of skeptics of homeopathy successfully resurrected in October, 2009, a House of Commons committee, called the Science and Technology Committee, with the intent to issue a report on homeopathy. A leading skeptics organization, Sense about Science, that has been pushing for the re-creation of this Committee is led by a former public relations professional who worked for a PR company that represents many Big Pharma companies. Of additional interest is the fact that other Directors of the Sense about Science organization are a mixture of former or present libertarians, Marxists, and Trotskyists who also, strangely enough, seem to advocate for the GMO industry (ironically, libertarians normally advocate for a "live and let live" philosophy, but in this instance, it seems that they prefer to take choice in medical treatment away from British consumers).

Sense about Science is a registered UK charity despite being a political pressure group. As such they have to divulge their sources of income which they do on their website. Not surprisingly, much of this comes from named pharmaceutical manufacturers.

One of the investigators for the House of Commons Science Committee is a Liberal Democrat MP, Evan Harris. He has collaborated with Sense About Science on various projects, and he was also one of the skeptic demonstrators against the national pharmacy chain, Boots, which sells homeopathic medicines. This advocacy role does not make him an unprejudiced observer as is required for this type of investigation.

A report from this kangaroo court was issued recommending that the National Health Service stop funding for homeopathy and homeopathic doctors, despite the support for homeopathy and for consumer choice from Mike O'Brien, the country's present Health Minister. This report is only of an advisory nature, and because the Health Minister has already expressed his support for consumers' right to choose their own health care, it is uncertain what, if anything, will result of this report. What was most surprising about this report was that it verified that when people repeat a lie frequently enough, such as "there is no research on homeopathy," many people actually believe it, despite its transparent falsity.Dana Ullman 05:33, 7 May 2010 (UTC)

Sources

I'm surprised that this article does not reference or discuss Paul Starr's Pulitzer Prize and the Bancroft Prize winning book on the social transformation of American medicine. Any article that wishes to understand the difference between allopathy and homeopathy needs to understand that this debate has less to do with science or medicine and everything to do with politics as the British report makes clear. Russell D. Jones 15:41, 2 March 2010 (UTC)

At one time, it was indeed appropriate to compare allopathy and homeopathy. While some dictionary definitions still use allopathy as a synonym for conventional medicine, I find the modern usage to be more often by CAM practitioners, as that-which-we-do-not-do. (For the record, I happen to find some complementary medicine useful, or at least worthy of trial in non-critical situations.)
As far as a "modern" comparison, however, I cannot do better than William Osler:

A new school of practitioners has arisen which cares nothing for homeopathy and still less for so-called allopathy. It seeks to study, rationally and scientifically, the action of drugs, old and new."(Flexner report, page 162)

Unquestionably, there was once a competition between something one could legitimately call allopathy, as a "doctrine of opposites", and homeopathy as a "doctrine of similars". Homeopaths often selectively quote Osler as saying that the homeopathic remedies were safer than most allopathic remedies of his era (i.e., late 19th-early 20th century). You'll note that there was insistence on keeping the 1905 quote from von Behring.
It ain't the 20th century any more, and conventional physicians don't prescribe based on opposites, nohow. Yes, there are political residues, but there's now a lot more in the way of evidence-based medicine...and protecting turf. Howard C. Berkowitz 19:37, 12 March 2010 (UTC)
My favorite quote from Paul Starr's book is: “Because homeopathy was simultaneously philosophical and experimental, it seemed to many people to be more rather than less scientific than orthodox medicine.” Dana Ullman 05:37, 7 May 2010 (UTC)

The memory of sugar

is being discussed here and provides a nice illustration of the topic. --Daniel Mietchen 21:56, 3 March 2010 (UTC)

I thought the "memory of sugar" tended to go either to the abdomen or buttocks, depending on genetics? :-)
Seriously, the discussion at that link is what I'd suggest is an expectation. It is possible to be neutral, I think, and mention, in the lede, that homeopathy is not generally accepted. We still do not have a way of dealing with the situation where homeopathy supporters will support a lede that doesn't consider it reasonably credible. Of course, in no other workgroup do we have an equivalent to the health sciences/healing art splits. Should Religion be joined by Atheism? Alternatively, is it possible to have a reasonable Atheism article in Religion? Howard C. Berkowitz 22:46, 3 March 2010 (UTC)
The problem just isn't there with religion and atheism. If you, say, are interested in philosophy of religion, you can get a degree in it regardless of whether you are an atheist or a theist (or something else entirely). I say this from experience - I have a BA in Philosophy, Religion and Ethics from a Catholic college but am an atheist. There are some - I guess the polite way of saying it is 'non-mainstream' - ways of getting a doctorate in religion. You could become a "Doctor of Scientology" (D.Scn) - I read today that Ron DeWolf - Hubbard's son - had been given one, and stated in court that he wasn't sure whether they gave him the Doctorate before or after he'd been given the Bachelors! Or you could get a phony Ph.D from a diploma mill - as quite a lot of the creationists have. The problem with Healing Arts is that you can quite feasibly become a Healing Arts editor with a degree from a non-mainstream parallel academic institution. When mainstream academia isn't bending over backwards to certify degrees in quackery (as two universities in Britain shamefully have), the quacks create their own academic institutions.
"Dr" Gillian McKeith "PhD" has a degree from a place called Clayton College of Natural Health in Birmingham, Alabama. Said college is not accredited by any accrediting body recognized by the Department of Education, and a number of states in the U.S. list it as unaccredited on their websites for student loans (etc.). This does not stop McKeith claiming to have a PhD on her website, nor did it stop Channel 4 television or her publisher from touting this to promote her books and TV programme. She also likes to mention how she is a member of the American Association of Nutritional Consultants. You too can be a member of the American Association of Nutritional Consultants if you send them $60! McKeith has pushed notorious nonsense like the idea that green vegetables are good for you because the green shows they have chlorophyll (true), and the chlorophyll will oxidate your blood (how? Human beings are not plants. They tend to get their oxygen through respiration rather than photosynthesis. And even if they were getting their oxygen through photosynthesis, even your local tanning salon lamps aren't quite powerful enough to penetrate your small intestines).
Another graduate of the Clayton College of Natural Health is cancer quack Hulda Clark who sells a whole variety of magic 'zapping' toys that make funny noises and shine lights and do little more to cure cancer than extract money from punters - I mean, cancer sufferers.
Take any philosopher of religion or even most theologians - they'll certainly be able to say something useful on an article about atheism in the Religion WG. Same for the non-believers within the same fields. The problem with Healing Arts is it lets people with completely bonkers views about reality approve articles on their favourite pseudoscience. If the claims of the homeopaths were true (and, blimey, even our politicians can tell what a big pile of nothing the evidence of two hundred years of homeopathy has amounted to), then most of the articles in the Biology and Chemistry workgroup need rewriting.
I'll repeat myself again: we need to fix the Healing Arts bug. It is nothing more than a bug. It is a bug that is bringing down the great work done by other WGs. It says to anyone who has spent years of their life working on getting a PhD in physics or literature or psychology or whatever that you can get a fake degree from a non-accredited university and also be considered an expert on the same level. How can I, in good conscience, tell the experts in my field to contribute given this significant vulnerability in the Editorship system? –Tom Morris 01:21, 4 March 2010 (UTC)
Religion seemed the obvious parallel, but we could, I suppose, have an Absolute Pacifism workgroup with Military -- not that quite a few professional soldiers don't hate war. Why can Engineering debunk a hoax theory but Health Sciences cannot? Howard C. Berkowitz 02:15, 4 March 2010 (UTC)
Howard, you're one of the eight Charterists. Are you a loud and strong voice therein trying to *remove* Healing Arts as a Workgroup, so that some of this nonsense could then be addressed in the future in a rational way? Hayford Peirce 02:49, 4 March 2010 (UTC)
Compromise in the Charter Committee, I believe, means that the Workgroup and some other details will be passed, without detailed guidance, to the Editorial Council. Personally, I am urging the draft to go to discussion and markup, so we can proceed to the next steps after ratification. While this is an especially galling problem, there are less egregious workgroup structure problems that also need addressing and can't happen at the Charter level. --Howard C. Berkowitz 03:21, 4 March 2010 (UTC)
Even with Pacifism and the Military, there is an implicit understanding that most of the facts are the same. The Pacifist will agree with the General that the U.S. dropped the bomb on Hiroshima or that Nelson died in 1805. They have different opinions, but they do not care out their own facts in quite the same way as the Healing Arts gang. –Tom Morris 07:32, 4 March 2010 (UTC)
No, the analogy may hold. There are those that will insist that any enemy can be defeated through passive resistance and good thoughts, just as some of the healing arts believe that it is utterly wrong to immunize against an infectious organism or use an antibiotic against one. Howard C. Berkowitz 07:43, 4 March 2010 (UTC)
Tom mentions non-mainstream ways of getting doctorates in religion. In fact the Archbishop of Canterbury still has the legal power to award them, which might explain why Church of England bishops always seem to be Dr. Peter Jackson 14:29, 12 March 2010 (UTC)

How well does it work?

We use double-blind studies to tell how well a particular medicine works. The person handout out the medicine does not know whether it's a "real medicine" just a sugar pill. In the case of pain relievers, the potency of an analgesic is rated in terms of how much more effective it is than a placebo.

If I recall correctly, as much as 75% to 90% of the effective pain relief you get from the pills comes from the placebo effect: you take your aspirin or ibuprofen or (without knowing it) your sugar pill, and your headache starts going away within an hour no matter what. The real stuff is only slightly better.

Given all that, how would we design a study to compare homeopathic treatment with conventional treatment? Is it possible to conduct a blind study, if the way the healer deals with the patient is a key ingredient of the therapeutic effect?

For that matter, how can we compare Freudian psychoanalysis to Berne's transactional analysis or modern rational-emotive therapy or to a frank chat with a trusted friend or mentor (like Father O'Malley down at the local Catholic church)?

  • I daresay one result of a careful attempt to measure outcomes could be that "bedside manner" is much more important than we've allowed ourselves to realize.

But I ask again, how do we study and quantify it? --Ed Poor 02:04, 28 March 2010 (UTC)

If one were to review the entire body of experiments that Thomas Edison conducted on electricity, one would have to say that the vast majority of his experiments were failures...and one might fall into a trap by saying that he was a failure. Of course, we KNOW that this is not true. Just because some studies have shown that homeopathic medicines don't work, there is a greater body of research to show that it does. The trick is to know WHEN homeopathic medicines work...and when they don't.
If anyone here wants to review a body of homeopathic research on a specific group of diseases (respiratory allergies) that have primarily been published in high impact conventional journals, such as the Lancet and the BMJ, you might consider reading this review of research I co-authored in a peer-review journal: http://www.ncbi.nlm.nih.gov/pubmed/20359268 -- you can read the entire article online at: www.altmedrev.com (It is in the Spring, 2010, issue, article #6). Dana Ullman 05:43, 7 May 2010 (UTC)

Unsupported assertions

The current text has "Even in Europe, homeopathy is practiced by many conventional physicians, including 30-40% of French doctors and 20% of German doctors." and in the next paragraph "Some medical doctors, particularly in Germany, France, and several other European countries prescribe homeopathic medicines for wide variety of both self-limiting conditions and serious diseases with a high rate of patient satisfaction." There are no supporting citations.

This is obviously redundant; we need at most one of these statements. However, neither strikes me as believable without support, so I am inclined to delete both. Anyone care to comment before I edit? Sandy Harris 15:29, 26 June 2010 (UTC)

Your point about unsupported assertions has come up before, and the current text, in my opinion, is significantly misleading. "homeopathy is practiced by many conventional physicians" does not, as much as some may want it to do so, imply that conventional positions endorse all of homeopathy. By definition, if they are conventional physicians, they are not practicing homeopathy as alternative medicine, but are using some complementary techniques from homeopathy. When I was last in my internist's office, I banged my shoulder against a piece of equipment. He rubbed it a bit. Does that mean he practices massage therapy?
"Patient satisfaction" is a purely subjective assessment and is in no way evidence of efficacy. I could take the sentence starting "Some medical doctors..." and substitute "chemically pure water that has not been exposed to a simillium" and demonstrate high patient satisfaction.
I agree with deleting both. Even if citations are offered, they must be of a quality that indicates that homeopathic methods are a significant part of the practice of these physicians and they are not using it with the intent of creating placebo effects. --Howard C. Berkowitz 17:05, 26 June 2010 (UTC)
It is a fact that at universities in Germany and Austria there are chairs and lectures on homeopathy (in Vienna also at the veterinary university). There are doctors who practice both. --Peter Schmitt 23:10, 26 June 2010 (UTC)
I have no problem if the two sentences ar combined. I think we've gone over this several times on the talk pages. As Peter points out, there are obviously well established 'conventional' medical professionals that use homeopathy for treatment of medical conditions. This is pretty much common knowledge at this point, so I don't see the need for citing a source for the mere fact that some medical physicians use homeopathy in their practices. However, when we add specific numbers such as 30-40%, it does seem to beg for a reference. It shouldn't be hard to find such a reference if it is out there. Otherwise, removing the numbers and just stating the fact shouldn't be a problem.
I don't think we will be able to find any scientific sources that conclude that they use it only on undereducated healthy people as a placebo. In fact, I think the opposite is more likely the case. D. Matt Innis 01:22, 29 June 2010 (UTC)

Would someone who has access care to correct the glaring English mistake in the first paragraph of this approved article? Ro Thorpe 00:16, 2 July 2010 (UTC)

I'm sorry, Ro, I must have a blind spot that is preventing me from seeing this glaring error. Could you be so kind as to point it out? D. Matt Innis 01:42, 2 July 2010 (UTC)
Oh, so go ahead and shoot me! I found it (after reading your request for Hayford to repair it :) D. Matt Innis 01:46, 2 July 2010 (UTC)
Bang, bang - but you've removed it! Many thanks! Ro Thorpe 12:16, 2 July 2010 (UTC)

I provide many solid references to the use of homeopathic medicines by physicians in Europe in an article I wrote at: http://www.huffingtonpost.com/dana-ullman/homeopathic-medicine-euro_b_402490.html (It is NOT my intent for anyone to reference this article in OUR article at this website. Instead, we can use many of the references provided. This article also has many references throughout the article showing that people who use homeopathic medicines tend to have more education than those who don't.)

I urge us to be very careful in significant changing this article because a lot of time and thought went into it previously. Dana Ullman 18:05, 14 July 2010 (UTC)

Review by a sceptical layman (i.e. me)

I'm reviewing the draft. Here is a rough summary of my changes and concerns:

  • I rewrote the paragraph in the lede section about the "long safety record". The reason homeopathy has a long safety record is the very same reason that not travelling has a long safety record: if something is inert and chemically indistinguishable from the delivery mechanism, it will be safe. Safety and efficacy is a balancing act. The reason homeopathy is safe is precisely because it isn't efficacious.
  • I'm not wild about long, windy footnotes about Romanization. I've thus split off the Romanization note about the word "qi" on to a separate page.
  • The section that is disputed about the number of practitioners in France and Germany is in the wrong place. The way in which homeopathy is prescribed or accessed doesn't seem to be to be a principle of homeopathy - homeopathy is homepathy whether it is prescribed by a homeopath or bought over the counter. I've thus moved it into the section which used to be titled "Professional homeopaths: who are they?" which I have retitled "Homeopathy in practice". This section seems to be the place to discuss provision, prescription, education, regulation and the like.
  • The paragraph starting "Homeopathic remedies can be prescribed by professional homeopaths" seems to be a tricky one. Depending on the country and the regulatory regime, homeopathy can be prescribed by a wide variety of people. Sadly (in my opinion), in Britain, quacks of all sorts can have their merry way with the public. Pretty much anyone can set themselves up as an alternative practitioner, so long as they don't make their claims too specific. But in other countries, this varies. It seems the important distinction that needs to be made is that homeopathy - unlike, for want of a better description, real medicine - can be prescribed by anyone.
  • The rest of the section on "A typical homeopathic visit" seems to have some glaring problems. The homeopath is supposed to have EMT training in order to be "adequately trained"? (Heh. Surely, if heart attacks are the problem, what you need to do is to dilute high-fructose corn syrup into non-existence and it'll clear right up? I thought they believed in the law of similars. What's a defibrilator doing in the homeopath's office?) But anyway, this adequate training is according to who? According to government regulations? According to the homeopathic groups? According to us? According to some third-party regulator like the CNHC?
  • The article describes "classical homeopathy" at length, but I haven't seen any discussion of what the alternatives are to classical.
  • There is a lot of repetition of parts of the article. The 'Principles' section is repeated in the section on 'The claims for homeopathy'.
  • No criticism seems to be made of the "treating the whole person" idea. I'm not even sure that this is a desirable thing. If I break my arm, I want my arm fixed, not someone to waffle about my "disturbance in the overall homeostasis of the overall being". In fact, when I broke my arm as a child, I'm very glad that I had access to a surgeon to fix it. This kind of rhetoric seems to be just an evasion tactic - if the studies don't show that homeopathy actually fixes anything (and, well, it wasn't going to put the bones in my elbow back together), then they can justify this kind of thing by pointing out that the person feels vaguely better in some holistic sense.
  • The paragraph about corticosteroids seems to be totally out of place. Oh, it sort of makes sense - it is a follow on from the last paragraph about homeopathy and asthma.

I've got a more radical suggestion. This article obviously needs a fairly ground-up rewrite. Here's what I reckon we should do. The current article seems to have been put together in a rather piecemeal way. Instead, I think the best way is to see if we can come together and work out a list of the fundamental questions that a good article on homeopathy should answer - then build a simple structure around those questions, and fill them in. We may be able to repurpose some of the text from the existing article.

I'd suggest the following list of questions:

  1. What is homeopathy?
  2. Is there any known mechanism for homeopathy?
  3. Is homeopathy clinically effective?
  4. What are the main issues of contention regarding homeopathy?
  5. Why have there been campaigns against homeopathy like the 10:23 campaign?
  6. What is the history of homeopathy? Who is Samuel Hahnemann?
  7. How is homeopathic care provisioned and regulated in different countries?

Before formulating a structure for any potential rewrite, I'm interested in seeing if anyone has any other questions that they'd want to add. –Tom Morris 12:30, 4 July 2010 (UTC)

Tom, I only have a few minutes right now, but let me share a thought or two. My greatest unanswered question is "what is the cognitive process of a homeopath in a patient interaction?" In other words, homeopaths say that every remedy is individualized. Whenever I posed this question to Dana, it was brushed aside, saying that one had to be a trained homeopath to understand.
Odd, but I have written quite a few articles on differential diagnosis in medicine, and some of my most interesting professional work is in expert systems to "individualize" (e.g., what dosage forms are most convenient for the patient and are most likely to be taken on schedule? What other diseases are present -- are there synergistic as well as problem interactions? Are there patient preferences? Are certain side effects more or less likely? Somehow, I manage to muddle through this sort of thing, yet I keep being told there are Inner Secrets to Homeopathy that prevent a straightforward explanation. Now, I'm not a classic layman in conventional medicine, but I can't think of a field where I don't have a basic understanding and the ability to quickly get a much deeper understanding -- and also know what I don't know. In the last six months or so, I've had to do the research to do peer interactions, on the specific diseases of people (two- and four-legged) for whom I'm an advocate and case manager -- involving human iron metabolism, feline squamous cell carcinoma, and peripheral nerve myelin protein 22 and inflammatory polyneuropathy. But I can't begin to understand how a homeopath thinks?
In fairness, I'm not sure how much time I'm willing to expend on homeopathy, at least unless I get comparable collaboration on less controversial, and possibly useful to more people, health science articles (to say nothing of other fields). Howard C. Berkowitz 13:26, 4 July 2010 (UTC)

Luc Montagnier

French virologist Luc Montagnier has said at a prestigious international conference when he presented a new method for detecting viral infections that it bore close parallels to the basic tenets of homeopathy. This has been published in the 'Sunday Times' (London), as well as 'The Australian' - here's a link to the article: http://www.theaustralian.com.au/news/health-science/nobel-laureate-gives-homeopathy-a-boost/story-e6frg8y6-1225887772305

I hope one of you (at least Dana) make time (I don't have the time) to insert this matter into this article.—Ramanand Jhingade 16:26, 5 July 2010 (UTC)

Here's another link: http://epaper.timesofindia.com/Archive/skins/pastissues2/navigator.asp?login=default&AW=1279125246109Ramanand Jhingade 16:37, 14 July 2010 (UTC)

I certainly have no intention of amending the article with newspaper articles, especially those that indicate nothing but a "close parallel." Has Dr. Montagnier's proposal been discussed in mainstream journals?
The first article, in The Australian, mentions a "memory of water" type argument, and cites rejection by other scientists. I'd note that his Nobel was for virology, not physical chemistry. The second is behind a paywall. Howard C. Berkowitz 16:58, 14 July 2010 (UTC)
Hi friends! Actually, I got sent this link to a recent issue of the "New Scientists" by none other than Nobelist Brian Josephson: <http://www.newscientist.com/article/mg20727682.300-60-seconds.html>
"Clear as a Nobel"
Luc Montagnier, the French virologist who won a Nobel prize in 2008 for linking HIV with AIDS, last week made controversial claims that highly dilute solutions of harmful viruses and bacteria emit low-frequency radio waves, allegedly from watery nanostructures formed around the pathogens. Similar claims have been made for homeopathic remedies." Dana Ullman 17:40, 14 July 2010 (UTC)
That link goes to the daily news summary, not anything on homeopathy. As quoted, though, they are "controversial claims". No details. Howard C. Berkowitz 17:57, 14 July 2010 (UTC)
It is necessary to have that link in this article to show that homeopathic remedies are not 'placebos', as some people allege.—Ramanand Jhingade 15:40, 16 July 2010 (UTC)
It is another piece in the puzzle. It is primary research, but it is by a Nobel Prize winner, so it is news about homeopathy. We shouldn't treat it as scientific fact, but it is a fact that a prominent scientist has made the statement that involves a quality of water. It is in no way scientific consensus, an in fact may lead to this guys ruin for whatever reason. We have included news about the British Medical Association's recent position statement concerning homeopathy and this article specifically mentions that statement as well. This is the draft, so I won't categorically remove something that is written comprehensively, neutrally, and objectively about the subject. D. Matt Innis 12:59, 17 July 2010 (UTC)

(undent) Matt, you give it a perfectly good context--as news. It doesn't show, or not show, anything about homeopathic remedies being placebos, or effective, or ineffective, or any particular clinical correlation. As far as I understand, he's made an observation in physical chemistry and RF fields interacting with water, nothing else. I sincerely hope he's not hurt, as he was incredibly dignified while there were attempts to discredit his initial discovery and characterization of HIV -- his Nobel was very deserved. Howard C. Berkowitz 19:42, 17 July 2010 (UTC)

My point in providing the link to the NEW SCIENTIST is to verify that this research is "notable," and as such, a short note is worthy here. Dana Ullman 05:35, 21 July 2010 (UTC)


Matt, you are wonderfully reasonable. Howard is not accurate when he says that Montagnier has "made an observation". Montagnier conducted RESEARCH, and he wrote about it in a peer-review journal. He spoke about it to a group of fellow Nobel Prize winners. And ALL of this was so notable that the "New Scientist" commented about it...and linked it directly to homeopathy. I have no problem if we choose to have the word "controversial" used in describing this new work. The fact of the matter is that this new work discusses "electromagnetic signaling" which may help explain how homeopathic medicines may work. Dana Ullman 18:29, 9 September 2010 (UTC)
Then why isn't the peer-reviewed journal cited, rather than Wired and The Australian? Further, one may write (e.g., an editorial) in a peer-reviewed journal, but not have one's work peer-reviewed by that journal. The peer review process becomes more credible if another independent researcher reproduces of these results. Please provide citations of these events if you want me to believe this is substantive.
Nobel Prize winners, rather by definition, tend to be specialists. One might speak on medicine to a group of Chemistry laureates, and have no special critical review.
It's interesting that we are still arguing how homeopathic medicines "may" work, when it's rather routine to understand the molecular pharmacology of conventional medicines. Sorry, this still comes across as hand-waving for something with a trivial base of evidence.
Have I fired five or six rounds? Howard C. Berkowitz 18:38, 9 September 2010 (UTC)

Evidence that homeopathy works

I hope one of you (at least Dana) can insert sentences that read something like, "there is scientific evidence for homeopathy", using the PDF for "Scientific framework of homeopathy: evidence-based homeopathy" available at http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewFile/286/354 wherever appropriate. I haven't seen anyone object to it here anyway.—Ramanand Jhingade 15:15, 21 July 2010 (UTC)

the word "skeptic"

Wasn't it decided a long time ago that aside from the two existing examples in the article that pro-homeopathy advocates (and anyone else) could NOT use the word "skeptic" in future edits? Just want to make sure. Hayford Peirce 21:50, 5 August 2010 (UTC)

I remember that as a specific ruling by Larry. In my experience, it's almost always used by advocates of a position; the neutrality policy wouldn't be hurt if it were banned. Howard C. Berkowitz 22:41, 5 August 2010 (UTC)
But what about people who are skeptics? Are we not allowed to say that Michael Shermer - who runs the Skeptic's Society and publishes Skeptic magazine - is a skeptic? –Tom Morris 23:02, 5 August 2010 (UTC)
As a direct quote or a self-identification, sure. As condescension to disbelievers, no. Howard C. Berkowitz 23:04, 5 August 2010 (UTC)
Ah, but is it? I consider 'skeptic' to be much less of an insult than 'homeopath'! –Tom Morris 23:06, 5 August 2010 (UTC)
I think it is -- it comes up repeatedly in fringe articles, be they moon landing hoax, UFO, etc. -- anything not a true believer. Howard C. Berkowitz 23:13, 5 August 2010 (UTC)
If *I* use the word, Tom, it's a compliment. If Dana uses it, it's pejorative. That's why Larry (or someone) banned it from this article, if I recall correctly. (I have 20 years' of Skeptical Inquirer on my bookshelf.) Hayford Peirce 23:21, 5 August 2010 (UTC)

What the...?

Homeopaths respond to these concerns by noting that using homeopathic medicines can delay or reduce the use of conventional medicines that are ineffective and dangerous.

If this were The Other Wiki, that'd be an instant "citation needed"! I know homeopaths like to bang on about the evil 'allopaths', but do they honestly respond to the opportunity cost argument with a reversed opportunity cost argument? That's so... indescribably crazy. I certainly would like some verification on that. –Tom Morris 00:42, 6 August 2010 (UTC)

Remember our motto: be bold -- remove it, and let whoever put it there back it up with some facts if they want to restore it. Hayford Peirce 01:42, 6 August 2010 (UTC)
Oh, now we're bold, haha. It's a response to the use of homeopathy for use with things like childhood ear infections, a commonly self limiting condition that is often treated with antibiotics which have unwanted and sometimes dangerous side effects. It probably could be explained a little better when it's all cleaned up. After all, that is the homeopath response. D. Matt Innis 21:50, 7 August 2010 (UTC)
On the other hand, I can point to many medical studies advising against antibiotics in uncomplicated otitis media. Going back to Osler at the turn of the 20th century, he correctly pointed out that "allopathic" drugs were often harmful -- but he then said both homeopathy and (classically defined) allopathy were "cults" that needed to be replaced. One doesn't need to turn to homeopathy to find best practices that avoid both overprescribing and underprescribing. Howard C. Berkowitz 21:59, 7 August 2010 (UTC)
Yup, absolutely agree. D. Matt Innis 01:10, 8 August 2010 (UTC)

principle of infintesimals

I'm thinking that principle needs defining. I'm thinking that the 'principle of infintesimals' is the concept that is controversial. Perhaps one of our homeopaths could explain? D. Matt Innis 12:32, 12 August 2010 (UTC)

Throughout this article, the infinitesimal dose and law of similars have been used interchangeably, but they aren't the same. http://www.similima.com/org20.html has given a brief description of the "infinitesimal dose". The law of similars is just, "using the most similar remedy" - to put it plainly. I don't have the time to check and insert those changes, but I hope you Matt, or may be Dana can do so. The infinitesimal dose can also be defended with the "memory of water" and Monsieur Montagnier's research (see Dana's post above).-Ramanand Jhingade 13:49, 13 August 2010 (UTC)
Certainly using them interchangeably is not accurate. D. Matt Innis 15:05, 13 August 2010 (UTC)
I think the term "interchangeably" was wrong to use - what I meant was that the term "law of similars" is used in the article and draft article, when it's supposed to be "the infinitesimal dose", in some places.—Ramanand Jhingade 15:50, 13 August 2010 (UTC)
So it seems to me that infinitesimal dose needs to be defined. The law of similars can obviously involve large doses of products. Obviously Homeopaths use more than infinitesimal doses in their treatments; otherwise we wouldn't have side effects from a nasal product that has zinc in it. We are not getting this point across. D. Matt Innis 17:47, 13 August 2010 (UTC)
I don't think it's worth the time, since that will also be criticized here (maybe you can use the web-site I mentioned above to do that). The nasal product, "Zicam" wasn't a homeopathic product at all, because it had milligram doses of zinc, which is against homeopathic principles. Homeopathic remedies start with mother tinctures and can go up to higher potencies (more dilute) from there.Ramanand Jhingade 09:50, 23 August 2010 (UTC)
Zicam was marketed as homeopathic, and licensed under special regulations applying to homeopathic products. Sorry, for legal purposes in the US, it was a homeopathic product. Howard C. Berkowitz 15:49, 24 August 2010 (UTC)
I know it was, but it was against homeopathic principles.—Ramanand Jhingade 15:39, 25 August 2010 (UTC)

(undent) Please do not use color for emphasis.

In the context of the United States, your simple statment that it "was against homeopathic principles" is legally irrelevant, as the FDA makes the decision if something is to be regulated as a homeopathic preparation (or food supplement), exempt from a good deal of the regulation of other drugs, or if it is a conventional regulated substance. The FDA determined Zircam was homeopathic, and, while I suppose you might argue, in an article about homeopathy and the FDA, such an argument is irrelevant here. If you reject the argument that a governmental organization cannot make such decisions for a country, then I can argue that homeopathy can't be accepted as a national means of practice in India.

With all things that it approves, the FDA depends on the manufacturer's application. More is accepted is fact in a homeopathic New Drug Application that isn't required to undergo controlled trials. Howard C. Berkowitz 16:57, 5 September 2010 (UTC)

Answer to an "unanswered question": Popularity is no metric of efficacy

Sorry, but the addition "The simple reason for homeopathy's growing popularity is because it works." is completely unacceptable without overwhelming evidence that it does work. Were this to be accepted without sourcing, the logic could be applied to popularity of politicians, especially not in office, supporting the premises their programs work.

I propose to delete this. Popularity is relevant to marketing but not efficacy. Howard C. Berkowitz 15:48, 24 August 2010 (UTC)

Those questions were begging for an answer. If you delete my answer, you must delete the questions preceding my statement as well!—Ramanand Jhingade 15:45, 25 August 2010 (UTC)
Your statement, unsourced, was not an answer. It was purely your opinion, phrased as informal commentary. Also, it is a rather sweeping opinion that goes to the heart of the article, with no evidence behind it. Howard C. Berkowitz 16:45, 25 August 2010 (UTC)
While Howard is right in saying that "popularity" is not a metric of efficacy, popularity is (by definition) its own metric, and statistics about homeopathy's popularity now and in the past has a place in an encyclopedia. Further, I give reference to a half-dozen

surveys that further verify that people who tend to receive homeopathic care tend to be more educated than those who don't.

The following link to an article that I authored provides references to this information (please know that I am not suggesting that we link to this article but only to use the references in this article in our encyclopedia listing: http://www.huffingtonpost.com/dana-ullman/homeopathic-medicine-euro_b_402490.html Dana Ullman 19:14, 9 September 2010 (UTC)
Post hoc, ergo prompter hoc? I can give even more studies that verify more people who drink milk become heroin addicts. Popularity is a principally a metric of efficacy -- of marketing. If it is significant here, Lady Gaga should be even more expert than Dana, and probably has a better figure. Howard C. Berkowitz 19:20, 9 September 2010 (UTC)

Allopathy

"Today, "allopathy" is used by practitioners of alternative and complementary medicine, like homeopaths, osteopaths, naturopaths, chiropractors and so on to refer to conventional, western medicine."

Since practitioners of conventional, western medicine rarely use the term, however, there's no good argument to insist on calling them allopaths. Yes, there are a few historical references, especially when talking of osteopathic vs. allopathic medical schools, but the term used by conventional western physicians tends to be...conventional western physicians.

Ramanand, if I refused to call you anything other than Jean-Paul, would that change your name? Howard C. Berkowitz 16:57, 24 August 2010 (UTC)

Practitioners of alternative and complementary medicine, like homeopaths, osteopaths, naturopaths, chiropractors and so on refer to conventional, western medicine as "allopathy" even today. If you don't like it, you can add something like, "conventional, western physicians do not refer to themselves as allopaths".—Ramanand Jhingade 15:50, 25 August 2010 (UTC)
Each profession defines what it calls itself. That is not the role of other professions. Would you accept the specific words "practitioners of conventional western medicine call homeopaths frauds?" No? Then why do you have the right to define a name, regarded by many as either historically inaccurate -- they don't use the principle of opposites -- or a sneering attack?. I wouldn't have the slightest objection if homeopaths called themselves Similarists, Hahnemannists, etc. -- but that is how they characterize themselves, not how they characterize others. Howard C. Berkowitz 16:44, 25 August 2010 (UTC)

Ruling needed

Mr. Jhingade reinserted "although osteopaths, homeopaths, naturopaths and other alternative medicine practitioners continue to call it allopathy." I will remove this unless an Editor says otherwise, as I believe it has been ruled that one discipline is not permitted to define a name for another. Shall I say "although biologically-oriented scientists consider homeopaths to be quacks? (noise made by the simillium of Oscillococcinum, of course)" At best, this might go in the allopathy article.

Osler deprecated both allopathy and homeopathy by the time of the Flexner report, although, somewhat earlier, he had attacked some of the drugs used by self-descibed allopaths. I'd note the latter was 19th century.

Be very careful, incidentally, in using "osteopath" versus "osteopathic physician". The latter, in the US, does use "allopath" but in a very narrow context dealing with the history of schools. Undergraduate and graduate medical education from traditionally "osteopathic" or "allopathic" education is largely identical, although some additional manipulative techniques may be taught in some historically osteopathic programs -- or by qualified faculty in historically "allopathic" programs. Assuming equal certification, with many boards merging, the scope of practice of DO's and MD's are identical. U.S. osteopathic physicians do not use the term allopathy in regular practice. Indeed, I know a few that don't use manipulation or any special osteopathic methods. As an aside, in the state of Virginia, to perform acupuncture, one must be licensed as a physician; the two I used were, respectively an MD with a OMD degree from Vietnam and a OB/GYN certification from FACOG; the other was an DO internist board-certified in internal medicine.

In the UK -- I can't speak authoritatively for the rest of Europe -- osteopathy is indeed a CAM discipline and its practitioners' scope of practice is not the same as a physician.

I would add that the opinions of naturopaths are irrelevant to this article.

Could we please stop refighting this revert battle? My impression is that rulings have been made.Howard C. Berkowitz 17:30, 5 September 2010 (UTC)

Practitioners of alt. med. still call it allopathy (Look at the American Association of Osteopathic Physicians web-site, the National Center for Homeopathy web-site and so on). I'm sure Dana will support me on this one. I'm looking forward to a ruling too and I believe such a ruling will support the homeopaths' viewpoint, because this article is titled Homeopathy and not, "Criticism of Homeopathy".—Ramanand Jhingade 08:44, 6 September 2010 (UTC)
If you are arguing from the perspective of the American Association of Osteopathic Physicians, you are either ignorant of the historical reason they do that, or deliberately making a false argument that American osteopathic physicians, as distinct from osteopaths in Europe, are in any way "alternative". DOs pass the same undergraduate and graduate certifications as MDs. I suppose I'll have to remind one of my DO friends, a world authority on field and disaster medicine, that he's "alt" and the surgeons shouldn't listen to him. If nothing else, there is a distinction between alternate and complementary.
As far as the National Center for Homeopathy website, what part of "one discipline doesn't specify what another calls itself" do you fail to grasp? I'm sure I can find medical sites that call homeopaths frauds and quacks; would you accept that designation? I'd have to go back into the archives, but I seem to recall that Larry ruled on this a long, long time ago. Dana does not have any editorial authority over what non-alternative practitioners call themselves.
If you think these comments are "attack on homeopathy", I refer you to the commentary of Dirty Harry Callaghan regarding the .44 Magnum. Howard C. Berkowitz 01:46, 7 September 2010 (UTC)

Matt's reversions

Matt, I see you have already reverted what I had added. I don't want to indulge in any "edit warring", so please restore what I had added. I have mentioned the reasons in the sections preceding this.—Ramanand Jhingade 16:20, 25 August 2010 (UTC)

Since you merely identify this a "Matt's reversions", it's difficult to what you specifically have in mind. Did Matt move the questionable material here for discussion? If he did, then it's appropriate to discuss it here, within policy limits, before it goes back.
If he deleted without making it clear what he was deleting, or why he was making a Healing Arts Editor decision to delete it, he needs to put it here. Otherwise, you cannot simply demand that it be put back without consensus or an Editor ruling. Howard C. Berkowitz 16:51, 5 September 2010 (UTC)
I'm in a hurry, but will make a quick reply. I hope Matt brings things here for discussion in future.—Ramanand Jhingade 08:38, 6 September 2010 (UTC)

"Attack piece"

The statement "Some other researchers claim that there is scientific evidence that homeopathy helps in many problems and diseases[3]" was added with the edit note that "the lede can't be an attack piece."

The lede also cannot be a place where non-substantive opinion can be used to "neutralize" the main thrust of expert opinion. Again and again, it's been pointed out that CZ's current neutrality policy does not mean that equal emphasis must be given to each position.

I recommend deletion of the above statement as far too general, and, for that matter, worded in a manner that really doesn't counter but says "well, yes but..." There's an old medical story about a radiologist who crawls, bloody and battered, into his emergency room. Asked what happened, he said it was "consistent with being mugged." Things in the lede need a bit more substance than "consistent with." Howard C. Berkowitz 17:19, 5 September 2010 (UTC)

I don't see any probs with that ref and I'm sure Dana, the only other Homeopath here will support me on that.—Ramanand Jhingade 08:34, 6 September 2010 (UTC)

Similars and "allopathic drugs"

First, I contend there is no such thing, in modern terms, as an allopathic drug. Got any references, such as Goodman and Gilman, that use the term? No, homeopathic texts don't get to define practices in general medicine. Taking a recent addition that I believe must be either radically changed or updated, I quote:

"Recent research has shown that some conventional drugs, which are normally used to do something, can do the opposite also - a rebound effect, similar to homeopathy's law of similars.[1][2]

[3][4]. [5][6] [7][8]. [9][10]"

First, it's impossible to respond to this deluge of citations without any details. Second, for these to be "allopathic" drugs, based on the "principle of opposites", the papers must include that language. Do they?

Second, it's a leap to equate a rebound phenomenon to allopathy; the dose-over-time, molecular control mechanisms, etc., are much more than "opposites". One of the classic examples of rebound, nasally applied vasoconstrictors, doesn't take place when the dose and duration are properly controlled. In general, if the vasoconstrictor is needed for long enough to cause rebound, use of antiinflammatories, such as corticosteroids, cromolyns, or antihistamines should be under active consideration to replace the direct vasoconstrictor.

It was with considerable restraint that I didn't immediately move this to the talk page. Ironically, there are very pleasant, collaborative discussions going on in a number of military and history articles. Maybe getting to kill people makes for more restrained discussion. Howard C. Berkowitz 19:04, 5 September 2010 (UTC)

The rebound effect is well documented and accepted in medical circles, so please don't delete that sentence or the refs I inserted (I've improved on the way it used to read, so pls take a look).—Ramanand Jhingade 08:31, 6 September 2010 (UTC)
Well documented? "Rebound effect' doesn't appear in the index of the standard textbook, Goodman and Gilman's The Pharmacologic Basis of Therapeutics (9th Edition). Now, as I have mentioned, the term "rebound" is indeed used in very specific contexts, such as the response of nasal mucosa to topical vasoconstrictors.
"can lead to the opposite effect, when stopped - a rebound effect, which means they are following homeopathy's law of similars." is not especially an improvement. Of course there are drugs that have adverse effects when stopped inappropriately. Corticosteroids, selective neurotransmitter uptake inhibitors and opioids all come to mind. "Similars" have nothing to do with it, in the sense that a corticosteroid, in a Proving, would be inflammatory. Instead, the adrenal cortex has reduced its production of endogenous steroids because it has sensed a certain blood level.
It's vaguely amusing to hear you comment about people ignorant of homeopathy, when there seem to be so many opportunities to be unaware of molecular pharmacology. But, there are different tastes -- where's the eye of newt and blood of bat when you need them? Howard C. Berkowitz 01:18, 7 September 2010 (UTC)

Dead link

http://www.medscape.com/viewarticle/511604 Reference 102 about the value of talking to patients. Howard C. Berkowitz 19:08, 5 September 2010 (UTC)

Then I suggest we remove the sentence attributed to Vandenbroucke.—Ramanand Jhingade 13:56, 6 September 2010 (UTC)

Thankless CZ

Editing CZ is a thankless job. I'm sure the people who are ignorant about a subject (like Homeopathy) can move on to Facebook, Orkut, Linked in, Twitter or some other networking site/s and make a lot of friends and get to know them really well - we hardly know anything about each other here. Howard, you're probably a nice guy I can get to know better and probably dine with. Sandy, Im sure I can make an interesting 'date'. Why don't y'all look for me on Facebook?—Ramanand Jhingade 13:56, 6 September 2010 (UTC)

I have nothing against friendship, and I do think I've found a number of good friends here. Nevertheless, the essence of what I see as appropriate writing at CZ depends on courtesy, but above all, logic -- western if you will -- and evidence. I have a LinkedIn account, but not Facebook, Twitter, etc. -- and don't want them. On the other hand, I am very active on an assortment of professional mailing lists. Howard C. Berkowitz 18:50, 6 September 2010 (UTC)
First off, I greatly doubt either of us would enjoy a date. 'Sandy' is a short form of 'Alexander', and I'm neither unattached nor gay.
Second, some of your other apparent assumptions are just as bogus. People generally aren't here for social networking, but to contribute toward building an encyclopedia. Nor does not being an expert on homeopathy preclude contributing.
I'm resisting the urge to write a more pointed reply because it would violate CZ:Professionalism#What_behaviors_are_unprofessional.3F. Sandy Harris 23:47, 6 September 2010 (UTC)

Confusing deletions

It's somewhat difficult to tell why things are deleted when the only reasons given are in edit notes, which aren't always easily accessible if, for example, minor edits follow them in the log.

This was deleted, possibly due a claim that it was unsourced -- yet it is sourced. It's a reasonable statement and belongs in the article.

This does not mean that that people treated with homeopathy do feel better as a result - the clinical literature clearly shows this, but Vandenbroucke suggested that this could be because its practitioners treatments spend more time with people than doctors do. "Even if people give you the wrong explanation about what you seek treatment for, the fact that they spend a long time speaking with you might help," Vandenbroucke suggests.[11]

"Homeopaths contend that flawed trials cannot be used to show that homeopathic treatment is ineffective (please read the previous paragraph for information about the positive trials)." This new sentence, especially the underlined words, is argumentative rather than informative. --Howard C. Berkowitz 18:50, 6 September 2010 (UTC)

I didn't do the above editing, though I support it. Just because Vandenbroucke says that statement does not mean it is true, especially when there is at present no data to support it. This idea borders on the preposterous that the "extra" time that homeopaths spend with their patients leads to the therapeutic benefits that homeopathic patients experience. If THAT were the case, then, psychologists would be our finest healers (and sadly, they are not). Although the first interview with a homeopath is typically an hour, the follow-up visits are usually 10-30 minutes, just a little longer than a conventional MD.
As for "flawed" trials, see my longer message in the next section where I talk about the importance of "internal validity" in trials AND "external validity." Dana Ullman 01:09, 14 September 2010 (UTC)

Dana Ullman's thoughts on this article to date

Sorry to be away from the article for so long...

I am very concerned about this present “draft” of the homeopathy article. I feel that it has lost its “encyclopedic” tone, and instead, it is a mixture of encyclopedic information along with strong “point of view” skepticism. Although I do not have a problem with proper skepticism, it is the tone of it AND where it is placed in the article that is critical.

For instance, in the very top portion of this article are paragraphs #3 and #4 which are not encyclopedic in tone or content.

I will try to avoid doing “editing” the article myself. Instead, I will propose here in the TALK section my ideas for what should be said, and I hope that those people who want to maintain a high-quality objective and encyclopedic article will make appropriate changes to the Draft. Needless to say, I will not sign my name, as a Healing Arts Editor, to anything that does not maintain a certain objective tone. And by “objective tone,” I obviously do not mean that this article should just a promo for homeopathy.

My sincere thanx for whoever re-formating my contribution so that we can communicate about them in bit-sizeable chunks. Good work! Dana Ullman 15:37, 14 September 2010 (UTC)

Dana on 3rd paragraph

Ultimately, I recommend some changes in the 3rd paragraph…here’s what I suggest for replacement for this paragraph.

While many medical practitioners prescribe some homeopathic remedies, a significant majority of the scientific and conventional medical community (including a number of national medical representative bodies like the British Medical Association), consider homeopathy to be unfounded and pseudoscientific.[1] Skeptics of homeopathy insist that there is no plausible mechanism to explain how the remedies might work, given that many of them are so dilute that they contain not a single molecule of the active ingredient. However, homeopaths and scientists from varied specialties, including Nobel Prize winning virologist Luc Montagnier, assert that there are viable theories about how homeopathic medicines may act, though as yet, no one explanation has been verified. Advocates assert that the homeopathic “principle of similars” is, in part, the basis for modern day immunizations, allergy treatments, and select other conventional treatments (ie, the use of Ritalin and other amphetamine-like drugs used to treat hyperactive children), while critics have compared it to sympathetic magic.
I wrote the current text. To me it seems accurate and encyclopedic, much better than either what it replaced or your suggestion.
My "While the founder of modern homeopathy was a medical doctor, some modern medical practitioners do prescribe some homeopathic remedies, and some governments do recognise homeopathy as legitimate treatment" instead of your "While many medical practitioners prescribe some homeopathic remedies" gives more arguments favorable to homeopathy, but states them more carefully, your "many" seems dubious to me.
My "the consensus of medical and scientific opinion is that homeopathy is unfounded." seems to me a simple statement of fact.
I removed the claim that it is "pseudoscientific", which seems to me true but unnecessary here. Criticism is fine; gratuitous insults are not.
I do not think the British Medical Association or your "However, ..." or "Advocates assert ..." belong in the lede. The lede needs to be a simple summary of key points. The BMA, Montaignier and Ritalin might all be discussed later, but they do not belong here. Sandy Harris 03:34, 14 September 2010 (UTC)

Greetings, Sandy...we've not interacted yet...let's work together. First, the claim in the present draft that "There is no plausible mechanism..." is false and has no place here. There ARE plausible explanations, though simply none that have been confirmed. Dana Ullman 15:20, 14 September 2010 (UTC)

It depends on the interpretation of the word "plausible". Certainly there are explanations, but I'd say none are plausible. Sandy Harris 02:31, 15 September 2010 (UTC)
Sandy suggests above that my reference to "many physicians" prescribing homeopathic medicines "seems dubious." Perhaps it would help if he re-read our article here where in the "Homeopathy in Practice" section gives some specific figures: "In Europe homeopathy is practiced by many conventional physicians, including 30-40% of French doctors and 20% of German doctors. Some homeopathic treatment is partly covered by some European public health services, including in France and Denmark. In France, 35% of the costs of homeopathic medicine prescribed by a medical doctor are reimbursed from health insurance."...Clearly, the term "many" is not dubious. Dana Ullman 15:48, 14 September 2010 (UTC)
See the discussion under "unsupported assertions" above. Those claims do belong somewhere in the article, if they can be supported, but the lede as it stands seems to me a good summary. Sandy Harris 23:21, 14 September 2010 (UTC)
I have a question for Sandy and Howard and other skeptics. At present, in this lede, there is the sentence: "To a skeptic, the 'principle of similars' is merely an appeal to sympathetic magic." Out of curiosity, do you believe that there is a certain wisdom of the body? Do you believe that the human organism tries to adapt to infection and/or stress by creating symptoms in order to survive? If you answer YES or MAYBE to EITHER of these questions, then using drugs that mimic the body's defenses make sense, and as such, we HAVE to delete or change this ill-founded sentence. Please also remember that the "high potencies" is only a part of homeopathy and that most homeopathic medicines sold in health food stores and pharmacies today are in small, material doses. It is inappropriate (and inaccurate) to assume that ALL homeopathic medicines are in doses beyond Avogadro's number. Dana Ullman 16:34, 14 September 2010 (UTC)
That sentence is fine. What we believe is not at issue. The paragraph is trying to summarise the position about homeopathy of skeptics and critics. I'd say that, if anything, it understates their revulsion. Granted, other parts of the article should give a much more favorable view, but the negative views should be there as well. Sandy Harris 23:21, 14 September 2010 (UTC)
Individual belief is outside the scope of the article, but no, I don't think there is a "wisdom of the body", and, using the medical definition of symptom, the body doesn't create any symptoms -- the mind does. Symptoms are subjective, and signs are objective. A sign may be evidence of a defense mechanism, but it's far more likely to be evidence of a disease process.
The great fallacy I see here is the assumption that proving-based drug mimic the actual defenses. The body's direct defenses against Clostridium tetani exotoxin in tetanus are immunologic. Those defenses are supported by administering synthetic tetanus immune globulin -- we learned to avoid the horse serum preparation as too risky -- to give initial passive immunity, and tetanus toxoid to build active immunity. These don't "mimic" the defenses; they are the defenses. The body really doesn't have defenses against the neurologic effects of the toxin, but benzodiazepines, neuromuscular blocking agents, baclofen and dantrolene provide what, I suppose, could be called "symptomatic" relief. Without getting into all the receptors, we have a pretty decent idea how these drugs reduce the spasticity; we don't need to go the route of finding similars.
I'm not opposed to using unusual explanations when there are no better ones. "Wisdom of the body" sounds like something for a Religion Editor. I do use complementary methods when I have some reason to believe in a favorable risk-benefit. As soon as I hear that something is risk free, alarm bells go off. There are always tradeoffs. I'm facing a terrible one now, as the American Veterinary Medical Association described euthanasia as a means of comfort care that has the side effect of death -- yet I have a beloved cat who has a greater will to live than any human I've ever encountered. Howard C. Berkowitz 23:56, 14 September 2010 (UTC)

The text you are questioning is "There is no plausible mechanism to explain how the remedies might work, given that many of them are so dilute that they contain not a single molecule of the active ingredient. To a skeptic, the "principle of similars" is merely an appeal to sympathetic magic." I think that is OK as it stands.

It could be replaced with something that both states the skeptical position better and mentions that not everyone is skeptical:

To a skeptic, there is neither any solid evidence that homeopathy is effective nor any plausible explanation of why it should be, and the "principle of similars" is merely an appeal to sympathetic magic. Homeopaths, however, believe that they have good answers to these criticisms.
Close. Let me urge that sympathetic magic show as a wikilink, as it is not just a throwaway pejorative, but an anthropological term that shows up across many cultures. Consider dropping the "merely". When I wrote the article on sympathetic magic, it wasn't intended to disparage, but to explain a cultural pattern.
Is it necessary to bring up both the Avogadro argument and similars in the lede, purely from a standpoint of complexity? Yes, I understand that potentiation is an argument that can be countered with the Avogadro point, but similars seem more basic than potentiation in understanding the core argument of homeopathy.
I am not trying to be argumentative when I say that arguing that the principle of similars is an equivalent or superior explanation, to a drug that was designed using molecular structure-activity relationships, is inflammatory. It's one thing for the homeopaths to say why their own preparations work, but it's pushing too hard to say that the homeopaths have better explanations for the drugs developed under different paradigms. Howard C. Berkowitz 02:46, 15 September 2010 (UTC)

4th paragraph

I believe that the present 4th paragraph has NO place in the top section. Discussion of the “possible dangers” from the patient or the doctor’s decision to not use conventional treatments has NO place here. If others wish to insert this information under its proper section, I do not have a problem, though we must then acknowledge: Homeopaths respond to the possible dangers from using homeopathic medicines in replacement of conventional medical care by asserting that there are much greater dangers by using conventional medicines as a first method of treatment.

It probably needs mention of the fact that homeopaths retort that conventional medicines may also have large risks. I'm inclined to think it does belong in the lede, since these risks are a basic issue about homeopathy. However, I don't feel remarkably strongly about that and would be interested in hearing other opinions. Sandy Harris 03:44, 14 September 2010 (UTC)
I would prefer to see it go unless the homeopaths present a statistical risk-benefit argument, based on modern medical practices, not 1900, that the hypothesis is true that the clinical outcome is better with homeopathic treatment than medical or no treatment. The risks of most medical treatments are quantifiable, as are the benefits, with the understanding that statistical aggregates do not apply to individuals.
There are any number of times I've chosen something with significant risk, because there was reasonable evidence the risk was greater than the benefit. Obviously, a cardioplegia solution that stopped my beating heart was risky, but the risk of not having the open-heart surgery was greater. There was reliable data for risk at each stage of the procedure.
When other children would chant "your mother wears army boots," I'd point out that they were part of her uniform. The "medical treatment is more dangerous", without substantial data, rings equally relevant to me. Howard C. Berkowitz 04:34, 14 September 2010 (UTC)
"I would prefer to see it go unless ..." is not clear to me. Are you saying that text on homeopathic rejoinders should not be inserted, or that we should follow Dana's suggestion and remove the current 4th paragraph from the lede? Sandy Harris 05:30, 14 September 2010 (UTC)
Unless the homeopathic rejoinder has strong statistical support, it should not be in the article. It's one thing if there is a formal risk-benefit analysis proving a hypothesis, but if it's no more than "well, medical treatments are dangerous," it's irrelevant defense. Howard C. Berkowitz 06:25, 14 September 2010 (UTC)

In due respect, the formal risk-benefit analysis needs to go BOTH ways. What evidence do you have for the "dangers" of receiving homeopathic treatment...and please do not give individual cases. I do have access to numerous cost-effectiveness studies showing significant cost savings to people who utilize homeopathic medicines. Dana Ullman 15:34, 14 September 2010 (UTC)

Bluntly, it does not need to go both ways. Homeopathy is desperately trying to claim a place at the table in the face of enormous evidence that molecular medicine is effective. It seems your position is that homeopathy and medicine are of equal status and that every claim against homeopathy must be counterattacked by one about medicine. If, indeed, homeopathy is so much an alternative to medicine, this is useless.
Incidentally, it would be wise for you to identify your financial interests in the promotion of homeopathy, such as (from http://www.homeopathic.com/main/bio_dana.jsp):
  • Dana Ullman, M.P.H. (Masters in Public Health, U.C. Berkeley) is "homeopathic.com" and is widely recognized as the foremost spokesperson for homeopathic medicine in the U.S.
  • Dana founded Homeopathic Educational Services, America's largest publisher and distributor of homeopathic books, tapes, software, and medicine kits. For 10 years he served as formulator and spokesperson for a line of homeopathic medicine manufactured by Nature's Way, one of America's leading natural products companies.
See Bob Badgett's developing article on conflict of interest. It is one thing for a practitioner to charge for professional services, but it is generally considered unethical for physicians to refer patients to testing facilities, publications, etc., from which they derive income.
You are the one making the claims that medicine is so dangerous. I didn't make claims about ""dangers" of receiving homeopathic treatment", which is a change of subject. I will say, however, that it is dangerous to seek homeopathic treatment in lieu of medical treatments of established efficacy. Now, that seems a backing-off from the dangers of conventional medicine, but there seems a dearth of such studies from sources not vested in homeopathy. Again, these studies need to be overwhelming to dispute the CZ policy of providing the mainstream view.
"NPOV", incidentally, is WP-speak and discouraged here.
Incidentally, apropos of being encyclopedic, how about contributions other than your single subject? Some of us are interested in building an encyclopedia, not fighting a never-ending battle with single-issue advocates or, as Sandy responded to Ramanand, social networking. Howard C. Berkowitz 16:48, 14 September 2010 (UTC)
Wow, Howard, you're now getting disperate...and I'm sorry to see this. First, for your information, I was personally asked by Larry Sanger (the founder of Citizendium) to edit here, and he asked me to become a Healing Arts Editor. I have never hid any fact about my background. In fact, most people appreciate my knowledge and expertise, except those few people who are threatened by facts, research, references to data, and the substantiation of information.
You and Sandy were asking me for "evidence" that conventional medicine has certain risks. While I could have laughed at this seemingly innocent (or naive) request, I simply responded by asking you to provide evidence that there was danger to homeopathic treatment. Instead of providing this evidence, you have chosen a different strategy to get your bias into this article. Let's avoid such tactics...and let's try to work together to write something fair, accurate, verifiable, and encyclopedic. Dana Ullman 22:26, 14 September 2010 (UTC)
No, I don't believe it is possible to collaborate with you to write something that is fair, accurate, and is not far more supportive of the benefits of homeopathy than is supportable by the views recognized by the bulk of medical opinion and data. I believe the best I can do is point out evasions, selective and often inaccurate statements about pharmacology, misquotations (e.g., saying Sandy or I asked for "evidence" medicine has risks), and what I believe to be a significant conflict of interest. I do so in discussion here, to be sure other members of the community see it, rather than jump into revert wars.
I have never suggested that medical treatment does not has risks; medical treatment always has risks. What I find to be hand-waving is the implication that homeopathy has no risks, including the delay of effective treatment.
You will note that I have asked for an Editor ruling on what I consider continued misues of von Behring as an authority that homeopathy works. I find it sad that regardless of what was done to design a treatment, the data-free argument that similars might be an explanation continues to be brought up.
Larry Sanger is not a health professional, and, I suspect, asked you to be a Healing Arts Editor because you are visible in that field. I would be much less antagonistic to your contributions were you to focus on what homeopaths believe and do, rather than the frequent -- and frequent inaccurate -- attacks on medicine, such as your condescending remark that there are no antifungal and antiviral agents of demonstrated efficacy, and, indeed, demonstrated risk. Indeed, the risk of unmodified amphotericin B has led to significant molecular work to reduce toxicity. You give the impression, however, that Hahnemann got it all right in the early 19th century, and medicine continues to get it wrong.
Professional collaboration does not require that participants like one another. It does not help when they are patronizing, and, if they can't take focused criticism without changing the subject, perhaps the kitchen of knowledge is a bit too hot. Howard C. Berkowitz 22:53, 14 September 2010 (UTC)

Howard, my concern about your editing is that you are just fabricating fights. You wrote above that I said "there are no antifungal and antiviral agents of demonstrated efficacy." Where (!) did I say OR simply imply that? Nowhere! I even repeated my point that we all have to be careful in making broad statement such as the "collective weight of evidence". THIS is what I mean by "straw men." You create arguments with yourself by making up what I say.

Where did you imply that? In an unsigned entry following mine of Howard C. Berkowitz 04:25, 14 September 2010 (UTC)
I am surprised and even a bit shocked to hear your assertion that antibiotics are effective for viral and fungal infections,
Obviously, I disagree, because I then listed numerous examples of antimicrobials effective against such infections.
If you want to accuse me of starting fights with myself, I'll simply conclude that one of me will always win. Howard C. Berkowitz 04:38, 15 September 2010 (UTC)


To clarify (again), my point is not that there are no risks to homeopathic treatment. However, IF we wish to highlight that there are certain risks to homeopathic treatment, we also have to acknowledge that it is widely recognized that there are much greater risks from conventional medical treatment. Dana Ullman 03:43, 15 September 2010 (UTC)

Certainly we should say somewhere in the article that there are also risks with other treatments, and that one of the arguments for homeopathy is that many of its remedies are low-risk. However, "it is widely recognized that there are much greater risks from conventional medical treatment" strikes me as something an encyclopedia cannot subscribe to without a lot more evidence.
In any case, I do not think a detailed discussion of risk issues belongs in the lede. I am inclined to thin the lede should raise the question, and in my opinion the current text does that adequately. Sandy Harris 04:12, 15 September 2010 (UTC)
I agree that a detailed discussion is out of place in the lede. If I may, I'll offer a fairly well-established risk of using homeopathic therapy as a first resort: myocardial infarction (heart attack). Assuming there are no contraindications to thrombolytic therapy, the window for optimal benefit from thrombolysis is 3-6 hours after onset, with declining benefit out to 12 hours. Thrombolysis can reverse the damage to the heart muscle if done within the window. I can cite any number of conditions where death can occur in hours or days without definitive therapy--tetanus is one. Of course, the best treatment for tetanus is prevention -- and TDAP and other immunizations are not designed by the principle of similars.
It's one thing to say that homeopathic remedies might be lower-risk in non-emergent situations, but that isn't what is being said. Of course, one could also say "it is widely recognized that there are much greater benefits, in serious conditions, from appropriate conventional therapy." No, appropriate conventional therapy does not, as been charged, extend to antibiotics for uncomplicated otitis media. Howard C. Berkowitz 04:38, 15 September 2010 (UTC)
In due respect, no one (!) has said or suggested that homeopathic medicines should be a treatment of first resort for heart attacks. THIS is what I mean by my concern for your tendency to create fights/arguments. Let's both avoid creating straw men. That said, I agree with Sandy that the lede should not have a detailed discussion of risks issues, though I would think that we might all agree that it is widely recognized that homeopathic medicines themselves are "basically safe." Also, can I ask us all to try to avoid inserting our own comments within the comments of other writers because it makes it challenging for people to determine who is saying what. Thanx. Dana Ullman 16:51, 19 September 2010 (UTC)
If it's alternative medicine, then it is the first resort. If it's complementary medicine, then there should be guidelines for the scope of practice of homeopathy. In the past, however, Ramanand has said homeopathy should be a first reatment for all manner of conditions. There was an extensive argument about acute asthmatic attacks, which, as I remember,
I am not creating a straw man. Please document when homeopathy should not be the treatment of first resort. Otherwise, I'll assume alternative medicine with no limitations.
Let me clarify my position. I would tend to say that homeopathic medications, themselves, are basically safe. I am very concerned that homeopathy, as a system of treatment, can be as deadly dangerous as a non-surgeon trying an advanced surgical procedure. You have yet to give information that documents what limitations homeopaths accept.
Please stop with the straw man accusations. I do not believe that any consensus is possible between alternative (i.e., not complementary) medicine and coventional medicine. Actually, I'd be far more likely to consult a shamanic healer than a homeopath, as there's a fair bit of documentation that shamans have a good understanding of psychosomatic medicine. I don't know what consensus could exist between someone that rejects the idea of treating the pathogens of infectious disease, and someone that has an understanding of modern microbiology. We, sir, are not on the same side and will not be. Howard C. Berkowitz 17:24, 19 September 2010 (UTC)

Rest of article

Further evidence of the strong POV and non-encyclopedic tone of this Draft is:

--under OVERVIEW: The first two sentences are “attack sentence.” It is clearly inappropriate to provide critique of a subject before adequately describing it FIRST. Those sentences must be removed or placed elsewhere.

I'd say at least the entire first paragraph and probably the whole "Overview" section should be deleted. None of it is real overview of the field. Sandy Harris 03:50, 14 September 2010 (UTC)
I agree with Sandy. There is no need for this "Overview" section, though I do believe that we need to place some of this information about the status and popularity of homeopathy in a section "Homeopathy in Practice." Dana Ullman 15:45, 14 September 2010 (UTC)

-- under OVERVIEW: Some sentences here are just confusing, especially this one and especially its last phrase: They are interested too in why some studies appear to have positive outcomes—do these reflect real efficacy, or can they be accounted for by flaws in study design or in statistical analysis, or "publication bias"—the tendency for small studies with chance positive outcomes to be published while studies with negative or inconclusive outcomes are not.

-- under HISTORICAL ORIGINS, it is confusing and surprising how or why Paracelsus was described as an “astrologer.” This field was not a primary area of his contributions. Just as the bio for Isaac Newton does not describe him as an astrologer, even though he actually wrote more on THIS subject than on mechanistic physics, we editors here know that Newton’s primary contributions to the modern-day have nothing to do with astrology. Needless to say, people here who want homeopathy to sound “quackish” tend to provide this biased information.

-- under HISTORICAL ORIGINS: Inaccurate information has been provided about the present status of the word “allopathy.” There is a long AND significant modern-day usage of this term by conventional medical organizations, medical schools, and state and national governments. Evidence for this is at: http://en.wikipedia.org/wiki/Talk:Allopathic_medicine (see “Hopping's huge list of links). Clearly, the term “allopathy” is still in extremely common usage, and it is simply inaccurate to say that it isn’t. In this light, Osler’s quote has no meaning here, though it may have a place in the article on “allopathy.”

-- under THE LAW OF SIMILARS: As much as I like the subject of “hormesis,” I do not associate its application with the law of similars nor do I know any reference to that. As such, the word “hormesis” has no place in THIS section. We could replace this word, hormesis, with the word “pheromones” because these substances are known to have a powerful effect in extremely small doses AND it is widely known that pheromones from one species are only sensed by those of a “similar” species.

-- under CLINICAL TRIALS TESTING THE EFFICACY… There are many sentences and paragraphs here that I could recommend changes, but I will emphasize those that are most important or most incorrect:

I recommend removal of the following short paragraph & its accompanying quote.

While many of these have indicated positive effects, generally, trials that are larger high-quality trials have tended to show little or no statistically significant effects, as was concluded by the authors of the second Lancet study cited above when they re-analyzed these trials.
“There is increasing evidence that more rigorous trials tend to yield less optimistic results than trials with less precautions against bias.”[98]

My explanation: First, the quote does not verify the sentence it is supposed to substantiate. Second, the article it quotes also asserts that it is a general finding in ALL clinical research that the higher quality trials tend to show less positive results. Third, the fact of the matter is that there are many high quality trials published in “high impact” journals that have shown statistically significant effects, including the four trials by Reilly, et al, the four trials on the treatment of influenza using Oscillococcinum, and the three trials on childhood diarrhea by Jacobs, et al.

We need to be careful in our review of research to avoid skewing the facts with “fudge” words. For instance, one could say that the “collective evidence” of the thousands of studies conducted by Thomas Edison was that electricity was not possible (because only ONE experiment in 1,000+ worked).

The challenge that we have in describing the efficacy (or lack of it) using homeopathic medicines is that we have to evaluate internal validity (how “high quality” were the trials?) AND external validity (is the specific medicine tested commonly used by homeopaths to treat people with that specific condition?). Skeptics of homeopathy tend to evaluate the internal validity issues and totally ignore the external validity issues…and BOTH are essential. To ignore external validity is akin to saying that antibiotics do not work for infections because the “collective weight” of studies on viral, fungal, and bacterial infection shows that these drugs do not work for this common group of diseases. Get it?

No. I don't get it, because I can demonstrate, in vivo and in vitro, that antibiotics do work for viral, fungal and bacterial infections. This is hand-waving and hardly encyclopedic.
I have repeatedly challenged you to respond to why homeopaths seem uninterested in the sort of trials used for customized pharmacogenomic medicine, which do have internal and external validity, and never have gotten an answer. Howard C. Berkowitz 04:25, 14 September 2010 (UTC)
I am surprised and even a bit shocked to hear your assertion that antibiotics are effective for viral and fungal infections, but I have no interest in arguing with you about these subjects here, though these strange assertions may influence your credibility with others. I take much more seriously your unfounded assertion that homeopaths are not interested in research that has internal and external validity. What is your evidence here?
Shocked? Now, if you are holding to the generally obsolete assertion that antibiotics are purely natural products, that's one thing. Let's see...viral? Neuraminidase inhibitors for influenza (as well as the older amantadine and rimantidine), ribavirin for Lassa fever and possibly other hemorrhagic fevers, protease inhibitors (as part of HAART) in lowering HIV levels...well, interferons might or might not be considered antibiotics, but have distinct roles in treating viral diseases. Fungal? Amphotericin B (amphotericin B lipid complex, amphotericin B cholesteryl sulfate, and liposomal amphotericin B); the conazole series; griseofulvin; flucytosine -- and that's not considering topical-only agents. Howard C. Berkowitz 17:07, 14 September 2010 (UTC)
Howard, you're missing my point here. My point is that one must be careful using the term "weight of evidence" because such terms group together various disparate treatments for various disparate conditions. Although I used the term "antibiotics," perhaps I should have used a name of a specific antibiotic, thereby showing that it may be effective for one type of infection but not for "all types" of infection. Likewise, testing homeopathic Arnica for one ailment may prove efficacious, but testing it for two other ailments might show that it is ineffective. One should not say that the "weight of evidence" is that Arnica is not effective. Instead, it is more accurate to say that Arnica is effective one condition but ineffective for two others. Get it now? I hope so...
My intention is not to "fight." My intention is for us to work together to provide verifable accuracy. Dana Ullman 22:37, 14 September 2010 (UTC)
Now I am confused. When you challenged fungi and viruses, it seemed you were challenging the existence of antimicrobial agents (a better term than antibiotic) for those organisms. I gave counterexamples.
No person with reasonable competence in infectious disease suggests there exists Panaceamycin, good for everything, any more than, presumably, Arnica is good for everything. Antimicrobial agents have reasonably well defined spectra, but, since they are directed against mutable living organisms, any competent hospital has a table ("antibiotogram") of the preferred agents for community-acquired and hospital-acquired infections in that locality.
Now, does the "weight of evidence" support appropriate antibiotic use? Yes! "Appropriate" does not include using antibiotics for self-limiting conditions unlikely to be affected by any antibiotic. Appropriate means considering the overall clinical picture -- sounds like the argument you make about syndromes -- such as not using penicillin G for exquisitely penicillin-sensitive streptococci, if the culture shows coinfection with Staphylococcus aureus or other penicillinase-secreting organism. One has to consider potential development of resistance, as well as the practical means of administration--if there is no one qualified to inject a parenteral antibiotic in home care, the antibiotic is irrelevant no matter how effective it may be against the organism. If there's a choice in a patient with a hearing loss, you avoid the especially ototoxic aminoglycosides.
Incidentally, I was just scratching the cognitive process in determining how to treat an infection. Howard C. Berkowitz 03:03, 15 September 2010 (UTC)
Just as doing double-blind and placebo controlled research testing surgical procedures have their methodological and ethical challenges, research on homeopathy has to be sensitive to the method itself. You cannot just test a homeopathic medicine and its effects on a bacteria in a petrie dish, nor can I test acupuncture by putting a needle in a petric dish full of bacteria. You've been told this many times in the past, and yet, you repeatedly feign ignorance about homeopathy and homeopathic research. Please...you're a smart guy. Let's discuss research that does exist. Dana Ullman 15:59, 14 September 2010 (UTC)
I repeat: there are usable methods that have been described for pharmacogenetic medicine. Let the clinician diagnose the individual treatment and send orders for it to the pharmacy. The pharmacy breaks the blinding code and dispenses either the ordered individual treatment or the control arm, the latter which may or may not be placebo. The safety committee monitors, and, assuming the study goes to completion, statistically evaluates the hypothesis that the experimental treatment arm is superior to control.
Incidentally, the piece of laboratory glassware is a Petri dish. If, however, you are referring to bacterial sensitivity testing, production tends to be done with radiochemistry, radioimmune reactions, or immunofluorescence. Consider me dumb since I don't know I'm feigning ignorance about homeopathy. Howard C. Berkowitz 17:07, 14 September 2010 (UTC)
"I've been told"...but by someone I find plausible? You have yet to answer my question about the cognitive process of a homeopathic session, claiming that only a homeopath can understand it, yet no medical discipline makes such a claim of inner mysteries. Howard C. Berkowitz 17:07, 14 September 2010 (UTC)
Howard, I am perfectly able to describe the cognitive process of a homeopath, but I don't think THAT has a place here. I've told you this before (many times!), and yet, you repeated request it. I'm writing this again because it seems that you don't want to remember. Sadly, you consistently seem to want to pick a fight, and you make these strange claims about homeopathy and homeopaths without evidence. To me, it just seems that you have a chip on the shoulder. I have no problems with you making verifiable statements or asking questions, but I do have a problem with you creating boogey-men when none exist.
I will say this: homeopaths usually prescribe their medicines for the overall "syndrome" of the patient, not just their "disease." Dana Ullman 22:46, 14 September 2010 (UTC)
I keep repeating it because you keep refusing to answer it, which I remember very well. Apparently, homeopathy is unique among healing arts and health sciences in not addressing cognition in practitioners.
I suppose that if I can't do better than century-old immunology and pronouncements that regardless of the molecular pharmacology that went into developing a drug, our old buddy similars might be the real explanation.
Sadly, you consistently want to pick a fight with anyone who doesn't regard homeopathy as the greatest thing for health. Howard C. Berkowitz 23:14, 14 September 2010 (UTC)

--Under GOVERNMENT AND INSTITUTIONAL… -- If we choose to include reference to the Great Britain’s House of Commons’ Science and Technology’s report on homeopathy, we have to make it clear that this report was voted on by an extremely small minority of its members. Of the 14 members, 10 did not consider this issue worthy of voting. Ultimately, a “majority” of only THREE members voted for this anti-homeopathy report. Of these 3 votes, two members were so new to the Committee that they did not attend a single hearing on the subject of homeopathy. The third vote for the “report” came from Evan Harris, a vitriolic antagonist to homeopathy who was not re-elected this year, losing to a 20-something year old political neophyte. Finally, because this report was “advisory” only in nature, the health minister overruled it and didn’t accept its conclusions. If anyone wants to make reference to THIS report, we have to add these important facts. I personally suggest that we do not cover this complicated and inconclusive decisions.

It should also be noted that whoever wrote the above was obviously also aware of these facts and choose not to present them. This type of biased reporting should not have a voice here. Let’s strive for more encyclopedic objectivity. Dana Ullman 01:21, 14 September 2010 (UTC)

Repeated defenses of homeopathy, with nothing more than supposition and coincidences, don't belong here either. In my opinion, Mr. Ullman, you will not regard anything short of an article that gives homeopathy as much credibility as conventional medicine as acceptable -- and that, sir, is a promo. Howard C. Berkowitz 04:25, 14 September 2010 (UTC)

Logical fallacies

Take the proposed statement "Advocates assert that the homeopathic “principle of similars” is, in part, the basis for modern day immunizations, allergy treatments, and select other conventional treatments (ie, the use of Ritalin and other amphetamine-like drugs used to treat hyperactive children), while critics have compared it to sympathetic magic. "

If anyone used the principle of similars to plan these treatments, there might be a case. I sincerely doubt, however, that this was ever done; the advocates making after-the-fact, observational rather than molecular, correlations that are extremely dubious. Take a modern immunization, especially an acellular one -- it is designed on a molecular basis to produce desired immunoglobulins and other specific substances; similars were not involved in the design. It's rather hard to say that "similars" is a better explanation than what the molecular pharmacologists intended, and can demonstrate.

Are there homeopathic provings that demonstrate that large doses of cromolyns cause basophil and mast cell degranulation? If not, the molecular explanation that they desensitize the granules, and in turn block the release of histamine and other inflammatory messengers, is a much better shave with Occam's Razor.

I hope we do not have as lengthy a debate on the Tooth Fairy, especially from advocates that are America's leading spokesman for tooth fairies and thus have a financial conflict of interest. Howard C. Berkowitz 01:57, 14 September 2010 (UTC)

Just to throw yet another bit of reality, the use of amphetamine-like drugs, as well as non-amphetamine drugs such as Strattera, for attention deficit disorder — not limited to children — and not discussing other psychotropic drugs is, to put it mildly, showing selection bias. There's as much evidence of neurotransmitter effects than of "similars". Further, if one were to generalize to other psychotropic drugs, one couldn't use the principles of similars to produce hypomania in a normal control. It has repeatedly been demonstrated that lithium carbonate, for example, is not euphoriant. In high doses, it's a depressant -- remarkably so, since the subject will be dead. Howard C. Berkowitz 04:25, 14 September 2010 (UTC)
We cite in this article a quote from Emil Adolph von Behring (the "father of immunology") who asserts, "In spite of all scientific speculations and experiments regarding smallpox vaccination, Jenner’s discovery remained an erratic blocking medicine, till the biochemically thinking Pasteur, devoid of all medical classroom knowledge, traced the origin of this therapeutic block to a principle which cannot better be characterized than by Hahnemann’s word: homeopathic." Whether physicians today (or yesterday) refuse to believe that the "principle of similars" is utilized in medicine, it still can be asserted that they are consciously or subconsciously utilizing it. This is NOT to say that ALL drugs are prescribed by this principle (Howard creates a straw man argument with his reference to lithium carbonate). Further, just because there are other explanations for how or why Ritalin works does not take away the fact that the "similars" principle may also be at play. Dana Ullman 16:14, 14 September 2010 (UTC)
Ah yes. von Behring. 1901 Nobel Prize for 19th century work. Got some authoritative immunology less than a century old? Maybe someone that knew about immunoglobulins?
"It can be asserted" and "just because there are other explanations" doesn't support similars, any more than the Illuminati might be responsible for all evil in international relations. "Might" isn't encyclopedic.
Actually, I prefer the wicker man to the straw man.
I'm disgusted, but I will not give up because the integrity of CZ means something to me. To stop responding to handwaving would be to give in to the stamina of homeopathic advocates.
You were the one that brought up various drugs. I added lithium carbonate as one example. How is it a straw man? In therapeutic doses, it has no effect on non-hypomanic patients. Easy to call things straw men when you don't like them, and drop back to "it can be asserted." The capability of assertion does not make for encyclopedic quality. Howard C. Berkowitz 17:16, 14 September 2010 (UTC)

Regarding 'point of view'

No "point-of-view" disparagement required for conclusions/inferences drawn from science. Any such disparagement itself reflects "point-of-view". The lede as it reads now reflects medical science's judgment of homeopathy. Personally, as a scientist, I consider an open mind a virtue, but I try not to have it so open my skeptical inquirer falls out. Anthony.Sebastian 03:16, 14 September 2010 (UTC)

As I've suggested, we have to face the issue that the two advocates appear not to want the general judgment to appear, unless it is immediately accompanied by a Seinfeld-like "but that's OK, and homeopathy works." Howard C. Berkowitz 04:25, 14 September 2010 (UTC)

Biology-Health Sciences Editor ruling needed

Immunology clearly falls into these fields, not Healing Arts. I contend that it is ludicrous for this article to be using von Behring as a source of authority. It's fair enough to mention a 1901 Nobel Prize winner in a historic context, but a ruling is needed if his statements on homeopathy and immunotherapy can be used as substantiation for plausible modes of immune response. Immunology has progressed a bit in over a century.

It's futile to argue this with Mr. Ullman, and I believe we have enough relevant Editors to settle this point. Howard C. Berkowitz 18:35, 14 September 2010 (UTC)

Agreed (sorry for butting in). (Chunbum Park 09:56, 15 September 2010 (UTC))
Don't feel sorry, Chunbum, your particpation and opinion is a valued part of the decision process.
This appears to be a bigger issue than homeopathy. It appears that you are asking to limit an editor on an article. We don't have a mechanism for that. We've really left that to the devices of other editors to challenge unusual statements by other editors. I would expect that even Dana would appreciate a immunologist's input, but regardless, they'd both still need resources to cite. I'm not sure that a Health Sciences Editor can overrule a Healing Arts editor on an article, but he can certainly challenge anything that counters his beliefs. I would think the EC or EiC would have to rule on something like that. Of course, that would be the Managing Editor should the new charter take effect. D. Matt Innis 12:59, 15 September 2010 (UTC)
That's much what I was thinking. To take a parallel example relevant to Howard, the article on the Iraq War might, and in my view should, discuss the question of its legality. But I don't suppose the article is affiliated to the Law Workgroup. So what happens with a hypothetical conflict between, say, Howard and a law editor on that question? I think the new EC has to think about the whole system here, not just leave it to the ME to invent precedents. Peter Jackson 15:03, 15 September 2010 (UTC)
Perfect example, Peter. The new charter should allow the new ME to make a decision on the fly based on ample input from everyone (especially editors) and then the EC can take its time to review the ME decision and either overrule it or support it. Hopefully, that will develop a sort of "case law" that eventually develop into policy based on a democratically expert debated concepts rather than customary consensus. Meanwhile, authors will be able to move on to different content while the decision is reached elsewhere. D. Matt Innis

(undent) All of you make good points, but the specific may be a little easier. If I were to state the problem in EC terms, it is that different disciplines acquire knowledge at different rates. Were this, for example, a Literature article, Oscar Wilde or G. B. Shaw's comments would be relevant. If this were aviation engineering, however, I think it is relatively obvious that Orville and Wilbur Wright's commentary would not be very relevant to an Airbus (most recent model) or Boeing 787 Dreamliner. While I've often wondered how a classic military genius such as Belisarius would do with airmobile forces, he'd have a bit of catching up.

Von Behring, and indeed Hahnemann, were giants in their time. Today, however, von Behring wouldn't know how to find his way to the protein sequencer or the molecular visualization workstation.

The policy, therefore, might say that to cite an authority as more than a historic point, that authority has to be reasonably familiar with current concepts. It may be even faster now, but, a few years ago, based on MEDLINE growth, the amount of information in health sciences doubled every seven years. Some fields, such as molecular pharmacology, went from nonexistent to major disciplines. There's not going to be a citation that "Von Behring is obsolete", but that's a reasonable inference.

Peter, I would be absolutely delighted to have an article on the legality of the Iraq War. The article is not now affiliated with law, or several other relevant workgroups, due to the three workgroup limit. In doing the main draft of these articles, I had quite enough to do with the "what" and "how" without getting into the just war theory or international law. I would be happy, over an appropriate beverage, to discuss what I personally consider to be vague language in the UN Charter.

Unquestionably, Matt, workgroups need to be revised. I have been doing some experimentation with subgroups, but they are not a sole answer. Howard C. Berkowitz 17:19, 15 September 2010 (UTC)

I think the word "ruling" in the section title is an error. Certainly comment, or even contributions, from those editors would be useful and (I assume) welcomed by all concerned, but I do not think they have the authority to rule here.
The paragraph quoting von Behrig starts "Scientists and medical doctors today do not think that the principle of similars is generally true or useful, and they explain the efficacy of vaccination without referring to it. Physicians of the 19th century however did consider that the principle could be valuable." That strikes me as fair. Given that context-creating text, I see no objection to the von B quote.
As I see it, there are serious issues with this article, and Howard is right about most of them. However, on this particular point, I see him as tilting at a windmill. Sandy Harris 02:52, 16 September 2010 (UTC)
One never knows...the windmills might be giants. Seriously, I really don't have a problem with historical quotes in historical contexts. Such contexts, though, would include both Osler's preference for 19th century homeopathy over 19th century allopathy, and his later statement that both allopathy (as used at the time) and homeopathy were both "cults" that needed to be replaced by scientific medicine.
Recent comments on this talk page, however:

Whether physicians today (or yesterday) refuse to believe that the "principle of similars" is utilized in medicine, it still can be asserted that they are consciously or subconsciously utilizing it. This is NOT to say that ALL drugs are prescribed by this principle (Howard creates a straw man argument with his reference to lithium carbonate). Further, just because there are other explanations for how or why Ritalin works does not take away the fact that the "similars" principle may also be at play. Dana Ullman 16:14, 14 September 2010 (UTC)

made me concerned that advocate(s) wanted to reintroduce the von B quote without the qualifiers, and suggesting that similars are the mechanism of medical immunization. That is not acceptable and is flatly wrong. I suspect that some of the molecular immunologists building acellular vaccines may never have heard of similars and certainly aren't designing with that principle, rather than protein structure-activity.
Lithium carbonate is hardly a straw man, as its activity would not be demonstrated in a proving on a non-hypomanic individual, only toxic effects in high doses. When things demonstate exceptions to basic concepts such as similars and proving, they become significant negative data. "It can be asserted" is hardly encyclopedic, thinking of the classic assertion that if my aunt had testicles, she'd be my uncle.--Howard C. Berkowitz 04:33, 17 September 2010 (UTC)

Howard C. Berkowitz 04:26, 17 September 2010 (UTC)

Followup on Anthony's comment about alternative medicine

While I agree with your addition, I wonder if it goes far enough. Complementary and alternative medicine, while often grouped together, are not the same. Alternative medicine, to use NCCAM's definition, is a substitute for conventional medicine, while complementary medicine can be integrated with conventional medicine. Rather by definition, alternative medicine will not agree with conventional medicine, and never the twain shall meet.

It's not implausible that there could be complementary homeopathy, but I find it interesting that the article really doesn't address it. At best, there are arguments that homeopathy is superior to conventional methods for specific disorders. There's some hand-waving that conventional physicians use homeopathic remedies in their practice, but no discussion of the indications and rationale for doing so. In other articles, there is discussion of the complemntary use of acupuncture, chiropractic, etc.

Whether or not homeopathy is CAM rather than AM, this article overwhelmingly treats it as AM. Howard C. Berkowitz 21:50, 14 September 2010 (UTC)

Howard, I took a long rest from this article, and it seems that you would really benefit from doing so too. I realize that by saying this you may now want to edit more often than ever. My concern is that you are beginning to lash out at me and at this subject in an extremely emotional way. It seems that you are no longer trying to create an encyclopedic article but one that pushes your POV which remain inadequately informed about this subject of homeopathy. Heck, even when Dr. J sought to reach out to Sandy and be friendly, rather than adverserial, Sandy told him that he wasn't interested. That's OK too...and Dr. J didn't seek to connect personally. Let's not make this effort by Dr. J to be as "bad" as you've tried to make it. Dana Ullman 22:54, 14 September 2010 (UTC)
Well, gee. I've been discovered: my whole motivation is attacking homeopathy, and I never, ever contribute to anything else at Citizendium. Obviously, New Delhi metallo-beta-lactamase-1 enzyme is just an attack on homeopathy, as is CZ: Pacific War Subgroup, as is (quite friendly) collaboration on opportunistic encryption.
Why is this in a subsection where I was addressing the complementary and alternative aspects of homeopathy? That was hardly emotional. I neither need nor want your advice or concern on what I should do.
It is adversarial. Deal with it. Mortality & Morbidity conferences, military After-Action Reviews, engineering design reviews, etc., benefit from an adversarial approach.
As far as I can tell, your definition of "adequately informed" is to accept homeopathy. The Ormus article hurt Citizendium, and I am convinced that homeopathy does as well. I do know that I have had people refuse to join CZ specifically due to the homeopathy article. I'll believe you want to be encyclopedic when I see you contribute to things other than a single issue.
If I get extremely emotional about something, I tend to be more quiet, and perhaps smile a lot. Howard C. Berkowitz 23:07, 14 September 2010 (UTC)

Encyclopedia Britannica Online: Homeopathy lede

Possibly of interest:

"Homeopathy"

"a system of therapeutics, notably popular in the 19th century, which was founded on the stated principle that “like cures like,” similia similibus curantur, and which prescribed for patients drugs or other treatments that would produce in healthy persons symptoms of the diseases being treated."

"This system of therapeutics based upon the “law of similars” was introduced in 1796 by the German physician Samuel Hahnemann. He claimed that a large dose of quinine, which had been widely used for the successful treatment of malaria, produced in him effects similar to the symptoms of malaria patients. He thus concluded that all diseases were best treated by drugs that produced in healthy persons effects similar to the symptoms of those diseases. He also undertook experiments with a variety of drugs in an effort to prove this. Hahnemann believed that large doses of drugs aggravate illness and that the efficacy of medicines thus increases with dilution. Accordingly, most homeopathists believed in the action of minute doses of medicine."

"To many patients and some physicians, homeopathy was a mild, welcome alternative to bleeding, purging, polypharmacy, and other heavy-handed therapies of the day. In the 20th century, however, homeopathy has been viewed with little favour and has been criticized for focusing on the symptoms rather than on the underlying causes of disease. Homeopathy still has some adherents, and there are a number of national and international societies, including the International Homoeopathic Medical League, headquartered in Bloemendaal, Neth."

http://www.britannica.com/EBchecked/topic/270182/homeopathy

Anthony.Sebastian 03:27, 16 September 2010 (UTC)

The first two paragraphs, I hope, are not controversial. The talk page controversy, however, has significantly involved both homeopathic attempts to claim medical logic, as well as a broader assumption, by the homeopathy advocates, that homeopathy needs to be regarded as having equal credibility to conventional medicine. Attempts to claim that the principle of similars is the underlying mechanism for medical treatments developed, or validated, using methods of molecular pharmacology fall under my first point. Closely coupled is the homeopathic argument that homeopathy mimics body defenses manifested as symptoms, when the actual defense is quite different than the symptom producing factor -- tetanus is a good example, where the defenses are immunoglobins that have no particular symptom-producing quality, but the symptoms of spasticity and convulsions are caused ("indirectly") by the exotoxin of Clostridium tetani and can be lethal. The defenses neutralize the toxin, and, coupled with antibiotics and surgery, eradicate the source of the toxin.
In other words, there's a refutation of molecular medical arguments, but no molecular explanation of how similars affect the body. Hand-waving about memory of water isn't on the same level as immune reactions that can be demonstrated in vitro and in vivo, or structure-activity interactions with cellular receptors. --Howard C. Berkowitz 23:12, 16 September 2010 (UTC)

"Alternative Medicine and the Laws of Physics"

Of possible interest:

Alternative Medicine and the Laws of Physics

Robert L. Park

Skeptical Inquirer, Volume 21.5, September / October 1997

http://www.csicop.org/si/show/alternative_medicine_and_the_laws_of_physics/

Anthony.Sebastian 03:59, 16 September 2010 (UTC)

Having read the article I feel a neutral way of presenting homeopathy would be something like "it is a type of medicine supported by neither scientific reasoning nor data. that being said this is what homeopaths think: 1, 2, 3." (Chunbum Park 05:40, 16 September 2010 (UTC))
I think that overstates the case. Homeopathy is based on a system that includes reasoning which is at least pseudo-scientific. There is data, though much of it is of dubious quality; in particular, "data" is not the plural of "anecdote". I don't think your text above is neutral in any sense I'd recognise.
The current draft includes "the consensus of medical and scientific opinion is that homeopathy is unfounded." I think that is accurate, neutrally stated, and sufficiently direct.
That said, I do think we should link to highly critical articles such as that one, possibly the rational wiki page, and certainly the lovely cartoon they use. Sandy Harris 07:40, 16 September 2010 (UTC)
See rational wiki's article "Citizendium" first. Anthony.Sebastian 03:57, 17 September 2010 (UTC)

Suggest ending Main Article draft at end of lede

Let reader use Biblio to get further information. Concentrate on thorough Biblio subpage. 06:39, 17 September 2010 (UTC)

I don't think that is an adequate approach for an encyclopedia. We want a reasonably detailed explanation here. That said, the article could likely be shortened significantly without losing anything valuable. Sandy Harris 12:14, 17 September 2010 (UTC)
At home much resource cost that could be going into even copy edit of other articles, articles that deal with topics that are likely to have more serious users? I'd wager that a good part of the hit count on this article is due to people at other wikis looking for controversy.
That being said, I'm not sure how feasible it is under present policy. Assume three Health Sciences and Biology Editors are willing to nominate the truncated approach for Approval. Healing Arts Editors say it is not Approvable. It would be one thing for a Mathematics Editor to question approval for a cryptographic topic written by a computers person, but we've gotten through effective collaboration among, say, Computers, Mathematics, and Military. Health Sciences and Healing Arts, among the workgroups, are the only case where we have different workgroups for fundamentally different views on the same subject area. It's a bug, not a feature; we don't have separate-but-equal Religion and Atheism workgroups. Howard C. Berkowitz 15:53, 17 September 2010 (UTC)

Definition

The current definition reads "System of alternative medicine that asserts — contrary to scientific evidence — that substances known to cause specific syndromes of symptoms can also, in very low and specially prepared doses, help to cure people who are ill with a similar syndrome of symptoms." I think that is a moderately awful definition. The problems I see are:

The "contrary to scientific evidence" bit, or similar text, has been added at least twice and reverted at least once. I don't think it belongs in the definition.
"syndrome of symptoms" is used twice. That's ghastly stylistically, "syndrome" is a technical medical term that may not belong here, and in any case, I suspect "syndrome of symptoms" is redundant. What else could you have a syndrome of? Or does a syndrome include more than just symptoms?

My version would be: A system of alternate medicine based on the idea that substances known to cause particular combinations of symptoms can, in very low and specially prepared doses, help to cure people who are ill with similar symptoms. (sig added later Sandy Harris 23:14, 17 September 2010 (UTC))

""Syndrome of sympoms", indeed, is ghastly. Unfortunately, it touches on a difference between homeopathic and current medical thinking that is as important as similars. Modern physicians look first for an etiological diagnosis: what is the cause of the patient's distress? (Note here that "symptom" is being used in a lay sense here -- there are differences of theory as well). Homeopaths consider that the "disease model", not patient-centric, and often reject a causality-based approach. Their focus is on the products of the cause (in medical thinking) or the body wisdom expressing its defenses.

A better wording would be welcome, but the rejection of etiologic thinking, and the focus on similars as a means of reducing symptoms, is fundamental. Howard C. Berkowitz 15:53, 17 September 2010 (UTC)

Sandy's version:

  • A system of alternate medicine based on the idea that substances known to cause particular combinations of symptoms can, in very low and specially prepared doses, help to cure people who are ill with similar symptoms.


My understanding:

  • A system of alternate medicine based on the idea that large dosages of substances known to cause particular combinations of symptoms in healthy individuals can, in very low and specially prepared doses, help to cure a person whose illness causes similar symptoms.

D. Matt Innis 21:49, 17 September 2010 (UTC)

I am quite willing to be corrected here, but I think the idea of an illness that creates similar symptoms is still too close to an etiologic model of disease to be accepted by homeopaths. While I don't have better words, my sense is they would say the symptoms are produced by the "wisdom of the body" as "defenses" and the remedies strengthen the defenses. --Howard C. Berkowitz 23:59, 17 September 2010 (UTC)


That could be the next sentence.


  • A system of alternate medicine based on the idea that large dosages of substances known to cause particular combinations of symptoms in healthy individuals can, in very low and specially prepared doses, help to cure a person whose illness causes similar symptoms. In essence, they believe that symptoms are produced by the "wisdom of the body" as "defenses" and homeopathic remedies are designed to strengthen those defenses.
D. Matt Innis 03:22, 18 September 2010 (UTC)
Add: They do not use the disease model of conventional medicine, in which there is a disease rather than an individual set of symptoms, and treatment directed at a cause of that disease as it presents in multiple patients. Howard C. Berkowitz 03:29, 18 September 2010 (UTC)
More work:
  • This contrasts with conventional medicine's "disease model" of treatment that looks to treat the disease process and therefore relieve the symptoms.
I'm not sure that's totally true, though. Many conventional treatments are directed at relieving symptoms, too.
D. Matt Innis 03:54, 18 September 2010 (UTC)

(edit conflict) (undent) There's a different philosophy in symptomatic treatment. If I sprained my ankle badly enough to need surgical repair, the cause would be relevant to a conventional orthopedist who needs to work on the damaged structures. Otherwise, the exact ligament stretch might be known, but it's not of therapeutic benefit. Symptomatic pain relief is the first consideration -- yes, rehabilitation may focus on exact etiology, but, for the sake of argument, assume it's self-limiting.

Sometimes, as with uncomplicated childhood otitis media, even if it is bacterial, antibiotic therapy may not be justified. Presumably, though, the child can still get acetaminophen.

In both of the cases above, there was awareness of an etiology, but a choice to treat only symptoms. Palliative care is often largely but not exclusively symptomatic -- still, an etiology would be necessary for chemotherapy or radiotherapy to slow the growth of an incurable tumor. Pain management, though, is symptomatic and even more important. Where does nursing care fit?

The homeopaths, however, appear to exclude the idea of treatment based on etiology, as opposed to symptom relief when the cause is either self-limiting or not treatable. I spend hours daily giving comfort care to my cat buddy, relatively little of which is directed at the cancer itself, but much more in nutrition, emotional support and wound care. Indeed, I am using some complementary medicine along with a lot more conventional things. Homeopathic ideas of symptom-oriented remedies don't enter into it. --Howard C. Berkowitz 04:28, 18 September 2010 (UTC)

I don't think either that long definitions are a good idea in general, or that the proposed "next sentences" are needed in this definition. In the article, certainly; in the lede, probably. However, the definition needs to be short and direct. In particular, it needs to be short enough to look reasonable when cited on a related articles page. Sandy Harris 04:46, 18 September 2010 (UTC)
If the definition is to be short, then, I believe the rejection of etiology is far, far more significant to homeopathy than the better-known issues of small doses. It appears to me that Hahnemann's insight dealt with symptoms being the essential manifestation of health or not-health, and only then did he go to the idea of provings and similars. My understanding is that his using provings for malaria had to do with the symptom production of quinine.
Absolutely, I forgot that we were working on the definition! You're right, Sandy. D. Matt Innis 21:27, 18 September 2010 (UTC)
I believe there's a comment on this page, from a homeopath, that homeopathic remedies are not always administered in homeopathic femtodoses.
The rejection of etiology is also key to much of the dispute with medicine, as I mentioned in terms of clinical trials. It is also, however, central to the medical rejection of some homeopathic approaches, such as the principal treatment for malaria being based on reducing Plasmodium parasites in the blood. Quinine remains a third-line drug for malaria, but its action in reducing fever and chills is due to its ability to suppress the parasites, not (in a medical view) what effects are caused by high doses of quinine. Howard C. Berkowitz 04:56, 18 September 2010 (UTC)
Quinine remains a third-line drug for malaria, but its action in reducing fever and chills is due to its ability to suppress the parasites, not (in a medical view) what effects are caused by high doses of quinine.
I think that's the point; it's not that homeopath's don't care about etiology, they just don't concern themselves with it. If it causes the same symptoms in a normal person, then it's used to treat the person that has those same symptoms, regardless of the cause. As you say, they might contend that the plasmodium is not what causes the symptoms, rather the symptoms are the body's response to plasmodium. To them it doesn't matter. D. Matt Innis 21:28, 18 September 2010 (UTC)
As my grandmother might have said, ah-HAH! Admittedly, I'm taking the example of the worst form of malaria, but a patient presenting with the cerebral form of Plasmodium falciparum malaria may well die in 18 hours. In general, the standard of medical care would be artemisinin-based combination therapy, with critical care support for effects such as acute respiratory distress syndrome or disseminated intravascular coagulation.
Quinine, in substantial doses and in combination with doxycycline, tetracycline, or clindamycin, be lifesaving. If I were the patient, however, and someone offered me homeopathic oral doses of oral quinine, I'd prefer a lethal dose of barbiturates, or a large-caliber bullet to the back of the neck (messy but fast).
Now, I'd have every respect for a complementary homeopath that suspected severe falciparum malaria, and immediately transferred the patient to medical care. Assuming such care were available, I'd regard an alternative practitioner as having, as the lawyers put it, depraved indifference for human life.. Howard C. Berkowitz 22:02, 18 September 2010 (UTC)
I suspect the cerebral form would have different symptoms, therefore different remedies as well. A bullet is probably not one of them. ;-) D. Matt Innis 23:40, 19 September 2010 (UTC)
Are you doubting the efficacy of a .45 caliber ACP 254-grain round, which is lead in a hardly homeopathic dose? Nevertheless, if I had cerebral P. falciparum malaria, I know that active medical treatment is still very iffy. Seriously, we have the problem of any validation here; I cannot imagine an ethics review board that would approve any treatment for such a life-threatening disease without overwhelming laboratory evidence for the control arm. Howard C. Berkowitz 22:21, 20 September 2010 (UTC)

Sandy's edit to the definition

...specifically "help to cure or prevent illnesses involving similar symptoms." While a homeopath will have to review this, I don't think "illnesses involving similar symptoms" is really a homeopathic concept. They certainly object to "diseases with similar symptoms", and tend to reject "disease" as a medical conceit. The symptoms are signals of the body's defenses to be strengthened, not the effects of a causative factor. Howard C. Berkowitz 04:59, 18 September 2010 (UTC)

I think you're splitting hairs, but, yes, let's hear from a homeopath on this. D. Matt Innis 21:27, 18 September 2010 (UTC)
Sandy's new definition is definitely an improvement. D. Matt Innis 21:32, 18 September 2010 (UTC)
Li'l hard pressed for time. I'm happy with Alexander's definition, but if you guys feel it needs to be simpler, I have a 'simpler definition', which would read:-

(Homeopathy is) an alternative system of medicine, which stimulates the natural healing processes of the body (with the help of sub-physiological doses of a remedy, by using its rebound effect), to restore health (homeostasis) in a sick person.

The matter in brackets is optional.—Ramanand Jhingade 07:36, 19 September 2010 (UTC)
Note that it is alternative medicine and not alternate medicine.—Ramanand Jhingade 07:44, 19 September 2010 (UTC)
Unfortunately, "rebound effect" is not a well-defined term, certainly in medicine, so should not be used in a definition unless it is well defined in an article of its own. The alternate definition depends heavily on homeopathic terminology, such as "natural healing processes", as well as using homeostasis is far broader a context than is used in the biological sciences -- to say nothing amout emerging concepts such as allostasis.
The proposed new definition also overemphasizes the aspect of small doses and does not address the apparent rejection, by homeopathy, of the idea of "disease". Instead, it speaks of "restoring health", without addressing the meaning of the state of non-health.
Please confirm or correct the statement that homeopaths do not believe in the concept of disease, in the sense that disease has an etiologic cause and the cause needs to be corrected. Howard C. Berkowitz 08:30, 19 September 2010 (UTC)
I agree with Howard here, Ramanand, that your version introduces too many vague terms to be considered for use as a one sentence definition. D. Matt Innis 23:44, 19 September 2010 (UTC)

What about

A system of alternative medicine based on the idea of stimulating the body's natural healing processes by administering tiny doses of substances which, when given in large doses to healthy individuals, cause similar combinations of symptoms.

I agree that Ramanand's definition has some problems, and I think the full version is too long, but it seems to me the point about stimulating natural defenses is central. Sandy Harris 03:07, 20 September 2010 (UTC)

  1. Kales A, Scharf MB, Kales JD (September 1978). "Rebound insomnia: a new clinical syndrome". Science (journal) 201 (4360): 1039–41. PMID 684426[e]
  2. Kirkwood CK (1999). "Management of insomnia". J Am Pharm Assoc (Wash) 39 (5): 688–96; quiz 713–4. PMID 10533351[e]
  3. Tsutsui S (2001). "A double-blind comparative study of zolpidem versus zopiclone in the treatment of chronic primary insomnia". J. Int. Med. Res. 29 (3): 163–77. PMID 11471853[e]
  4. Hohagen F, Rink K, Käppler C, et al. (1993). "Prevalence and treatment of insomnia in general practice. A longitudinal study". Eur Arch Psychiatry Clin Neurosci 242 (6): 329–36. DOI:10.1007/BF02190245. PMID 8323982. Research Blogging.
  5. Reber, Arthur S.; Reber, Emily S. (2001). Dictionary of Psychology. Penguin Reference. ISBN 0-140-51451-1. 
  6. Kales A, Soldatos CR, Bixler EO, Kales JD (April 1983). "Early morning insomnia with rapidly eliminated benzodiazepines". Science (journal) 220 (4592): 95–7. PMID 6131538[e]
  7. Lee A, Lader M (January 1988). "Tolerance and rebound during and after short-term administration of quazepam, triazolam and placebo to healthy human volunteers". Int Clin Psychopharmacol 3 (1): 31–47. DOI:10.1097/00004850-198801000-00002. PMID 2895786. Research Blogging.
  8. Kales A (1990). "Quazepam: hypnotic efficacy and side effects". Pharmacotherapy 10 (1): 1–10; discussion 10–2. PMID 1969151[e]
  9. Hilbert JM, Battista D (September 1991). "Quazepam and flurazepam: differential pharmacokinetic and pharmacodynamic characteristics". J Clin Psychiatry 52 Suppl: 21–6. PMID 1680120[e]
  10. Adam K; Oswald I (May 1989). "Can a rapidly-eliminated hypnotic cause daytime anxiety?". Pharmacopsychiatry 22 (3): 115–9. DOI:10.1055/s-2007-1014592. PMID 2748714. Research Blogging.
  11. medscape