Interleukin-2: Difference between revisions

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'''Interleukin-2''' is an [[interleukin]] generated by [[lymphocyte#T4 helper cells|T4 helper lymphocyte]]s. It  induces DNA synthesis in naive lymphocytes.  Other terms include Lymphocyte Mitogenic Factor, T-Cell Growth Factor, Thymocyte Stimulating Factor and T-Cell Stimulating
'''Interleukin-2''' is an [[interleukin]] generated by [[lymphocyte#T4 helper cells|T4 helper lymphocyte]]s. It  induces DNA synthesis in naive lymphocytes.  Other terms include Lymphocyte Mitogenic Factor, T-Cell Growth Factor, Thymocyte Stimulating Factor and T-Cell Stimulating Factor.<ref>{{MeSH}}</ref>
 
The gene expresses when  stimulated by human T-cell leukemia virus Type 1.<ref>{{citation
| url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1167238/pdf/emboj00174-0145.pdf
| journal =  EMBO Journal | volume = 5 | issue =  11 | pages  =2883-2888 
| year = 1986
| author = Jun-ichiro Inoue ''et al.''
| title = Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1}}</ref>
 
[[Thalidomide]] has a costimulatory or adjuvant effect on [[T-lymphocyte]]s resulting in increased T-cell proliferation and increased production of interleukin-2  and [[interferon gamma]].<ref>{{citation
| url = http://www.medscape.com/druginfo/monograph?cid=med&drugid=16389&drugname=Thalidomide+Oral&monotype=monograph&secid=8
| title = Monograph: Thalidomide &mdash; Pharmacology
| publisher = American Society of Health System Pharmacists/Medscape
}}</ref>
 
==References==
{{reflist|2}}[[Category:Suggestion Bot Tag]]

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Interleukin-2 is an interleukin generated by T4 helper lymphocytes. It induces DNA synthesis in naive lymphocytes. Other terms include Lymphocyte Mitogenic Factor, T-Cell Growth Factor, Thymocyte Stimulating Factor and T-Cell Stimulating Factor.[1]

The gene expresses when stimulated by human T-cell leukemia virus Type 1.[2]

Thalidomide has a costimulatory or adjuvant effect on T-lymphocytes resulting in increased T-cell proliferation and increased production of interleukin-2 and interferon gamma.[3]

References

  1. Anonymous (2024), Interleukin-2 (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Jun-ichiro Inoue et al. (1986), "Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1", EMBO Journal 5 (11): 2883-2888
  3. Monograph: Thalidomide — Pharmacology, American Society of Health System Pharmacists/Medscape