Zanamivir

zanamivir
IUPAC name: see chemistry section Synonyms: Relenza® Formula: C12H20N4O7
Uses:	influenza A & B
Properties:	neuraminidase inhibitor
Hazards:	see drug interactions
Mass (g/mol): CAS #: 332.3098 139110-80-8

Zanamivir is a guanido-neuraminic acid that is a neuraminidase inhibitor used as an antiviral drug to treat influenza A and B.

Its IUPAC chemical name is (4S,5R,6R)-5-acetamido-4-(diaminomethylideneamino)-6-[(1R,2R)-1,2,3-trihydroxypropyl]-5,6-dihydro-4H-pyran-2-carboxylic acid and its chemical formula is C₁₂H₂₀N₄O₇.

Dosage

According to MedMaster, "the recommended dose of RELENZA for treatment of influenza in adults and pediatric patients ages 7 years of age and older is 10 mg twice daily (approximately 12 hours apart) for 5 days." Zanamivir is administered by inhalation and is supplied at 5 mg blister per dose so 20 blisters are needed. One Relenza Diskhaler contains 20 blisters.

Brand names

• GANA
• GNA
• Relenza (GlaxoSmithKline)
• ZMR
• Zanamavir

External links

The most up-to-date information about Zanamivir and other drugs can be found at the following sites.

• Zanamivir - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Zanamivir - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
• Zanamivir - Detailed information from DrugBank.