Amprenavir: Difference between revisions

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[[Image:Amprenavir structure.jpg|right|thumb|200px|{{#ifexist:Template:Amprenavir structure.jpg/credit|{{Amprenavir structure.jpg/credit}}<br/>|}}Amprenavir.]]
{{Chem infobox
|align=right
|image=[[Image:Amprenavir structure.jpg|center|thumb|200px]]
|width=200px
|molname=amprenavir
|synonyms=  AMP, AMV, APV, VX-478
|molformula= C<sub>25</sub>H<sub>35</sub>N<sub>3</sub>O<sub>6</sub>S
|molmass= 505.6269
|uses=HIV
|properties=protease inhibitor
|hazards=see drug interactions
|iupac= see chemistry section
|casnumber= 161814-49-9
}}


'''Amprenavir''', also called AMP, AMV, APV and  VX-478,  is a protease inhibitor used to treat HIV infection.  Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1.  Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.
 
'''Amprenavir''', also called AMP, AMV, APV and  VX-478,  is a [[protease inhibitor]] used to treat HIV infection.  Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1.  Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-
hydroxy-1-phenylbutan-2-yl]carbamate.


== Brand Names ==
== Brand Names ==
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== External Links ==
== External Links ==
* {{DailyMed}}
{{CZMed}}[[Category:Suggestion Bot Tag]]
* Drug Bank at http://www.drugbank.ca/cgi-bin/getCard.cgi?CARD=DB00701

Latest revision as of 06:00, 10 July 2024

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Amprenavir structure.jpg
amprenavir
IUPAC name: see chemistry section
Synonyms: AMP, AMV, APV, VX-478
Formula: C25H35N3O6S

 Uses: HIV

 Properties: protease inhibitor

 Hazards: see drug interactions

Mass (g/mol): CAS #:
505.6269 161814-49-9



Amprenavir, also called AMP, AMV, APV and VX-478, is a protease inhibitor used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3- hydroxy-1-phenylbutan-2-yl]carbamate.

Brand Names

  • Agenerase®
  • Prozei®
  • Vertex®

External Links

The most up-to-date information about Amprenavir and other drugs can be found at the following sites.