Mixed connective tissue disease: Difference between revisions

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imported>Howard C. Berkowitz
(New page: {{seealso|Scleroderma}} Now understood to be a distinct disease, '''mixed connective tissue disease (MCTD)''' is variously considered an overlap between systemic lupus erythematosus, scler...)
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Revision as of 07:40, 31 July 2010

See also: Scleroderma

Now understood to be a distinct disease, mixed connective tissue disease (MCTD) is variously considered an overlap between systemic lupus erythematosus, scleroderma, and polymyositis; a specific subest of scleroderma with objective features of other diseases, such as SLE or polymyositis; or a distinct disease entity.

Most patients with MCTD have autoantibodies to U1 small nuclear ribonucleoproteins (anti-U1 snRNP OR anti-U1 RNP),