Granulocyte colony-stimulating factor: Difference between revisions

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(New page: '''Granulocyte colony-stimulating factor (G-CSF)''' is a glycoprotein of MW 25 kDa, which stimulate the production of neutrophils and their precursors, and is used to treat [[neutrope...)
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Revision as of 10:28, 30 July 2010

Granulocyte colony-stimulating factor (G-CSF) is a glycoprotein of MW 25 kDa, which stimulate the production of neutrophils and their precursors, and is used to treat neutropenia.

It is a glycoprotein containing disulfide bonds, which has a molecular waight of 25 kilodalton (kDa) Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.[1]

It is not the same agent as granulocyte-macrophage colony-stimulating factor (GM-CSF), the synthetic version of which is filagastrim.