Glycylcycline/Related Articles

Glycylcycline: A new class of antibiotics, derived from tetracycline but with a molecular structure designed to evade tetracycline resistance mechanisms; tigecycline is the first approved drug of the class ^[e]

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Parent topics

• Antibiotic [r]: Drugs that reduce the growth or reproduction of bacteria. ^[e]
• Antibiotic resistance [r]: The development of resistance to an antibiotic in an organism originally susceptible to it ^[e]
• Tetracycline [r]: Both a class of naphthacene antibiotics, and a specific member of the class, which inhibit amino alkyl transfer RNA binding during protein synthesis ^[e]

Subtopics

• Tigecycline [r]: First commercially available antibiotic of the glycylcycline class, which has a broader spectrum than the tetracyclines from which it is derived, and overcomes a number of tetracycline resistance mechanisms ^[e]

Other related topics

• Surgical wound infection [r]: Infections that occur at the site of a surgical incision ^[e]

Susceptible organisms

• Acinetobacter [r]: A genus of bacteria, common in soil, but increasingly common as a human and animal pathogen, with multidrug resistant forms of special concern; the most common infectious species is A. baumanii ^[e]
• Enterobacteriaceae [r]: Add brief definition or description

Other drugs for same targets

• Imipenem [r]: A broad-spectrum antibiotic effective in many multidrug-resistant or multiple-organism infections; chemically contains a beta-lactam ring but is neither a penicillin nor a cephalosporin ^[e]
• Vancomycin [r]: A glycopeptide antibiotic used in the prophylaxis and treatment of infections caused by Gram-positive bacteria, especially methicillin-resistant Staphylococcus aureus (MRSA) ^[e]