Liver failure: Difference between revisions
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Revision as of 14:41, 1 January 2010
In medicine, liver failure, also called hepatic failure is "severe inability of the liver to perform its normal metabolic functions, as evidenced by severe jaundice and abnormal serum levels of ammonia; bilirubin; alkaline phosphatase; aspartate aminotransferase; lactate dehydrogenases; and albumin/globulin ratio."[1]
Treatment
Among patients with hepatic encephalopathy grades I-II and international normalized ratio ≥ 1.5, intravenous N-acetylcysteine (NAC) for 72 hours may reduce the need for liver transplantation.[2] The trial did not appear to have patients with liver failure due to ethanol.
References
- ↑ Anonymous (2024), Liver failure (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Lee WM, Hynan LS, Rossaro L, Fontana RJ, Stravitz RT, Larson AM et al. (2009). "Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure.". Gastroenterology 137 (3): 856-64, 864.e1. DOI:10.1053/j.gastro.2009.06.006. PMID 19524577. Research Blogging.