Insulin resistance: Difference between revisions
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:<font face="Gill Sans MT">Diminished effectiveness of [[insulin]] in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent [[hyperglycemia]] or [[ketosis]].</font><ref name=meshir>{{MeSH}}</ref> | :<font face="Gill Sans MT">Diminished effectiveness of [[insulin]] in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent [[hyperglycemia]] or [[ketosis]].</font><ref name=meshir>{{MeSH}}</ref> | ||
It can be caused by the presence of insulin antibodies or the abnormalities in insulin receptors (receptor, insulin) on target cell surfaces. It is often associated with [[obesity]]; [[diabetic ketoacidosis]]; [[infection]]; and certain rare conditions. | It can be caused by the presence of insulin antibodies or the abnormalities in insulin receptors (receptor, insulin) on target cell surfaces. It is often associated with [[obesity]]; [[diabetic ketoacidosis]]; [[infection]]; and certain rare conditions. | ||
[[Insulin resistance]] (HOMA-IR) can be measured by:<ref name="pmid3899825">{{cite journal |author=Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC |title=Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man |journal=Diabetologia |volume=28 |pages=412–9 |year=1985 |pmid=3899825 |doi= |url= |issn=}}</ref> | [[Insulin resistance]] (HOMA-IR) can be measured by:<ref name="pmid3899825">{{cite journal |author=Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC |title=Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man |journal=Diabetologia |volume=28 |pages=412–9 |year=1985 |pmid=3899825 |doi= |url= |issn=}}</ref> | ||
Revision as of 16:04, 21 February 2013
- See: Article on insulin, if necessary, to better understand present article.
--- As described in the 2013 Medical Subject Headings of the National Library of Medicine, insulin resistance consists of
- Diminished effectiveness of insulin in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent hyperglycemia or ketosis.[1]
It can be caused by the presence of insulin antibodies or the abnormalities in insulin receptors (receptor, insulin) on target cell surfaces. It is often associated with obesity; diabetic ketoacidosis; infection; and certain rare conditions.
Insulin resistance (HOMA-IR) can be measured by:[2]
References
- ↑ Anonymous (2024), Insulin resistance (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985). "Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man". Diabetologia 28: 412–9. PMID 3899825. [e]