Cephalosporin: Difference between revisions
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imported>David E. Volk (New page: {{subpages}} [[Image:Cephalosporin base.jpg|right|thumb|250px|{{#ifexist:Template:Cephalosporin base.jpg/credit|{{Cephalosporin base.jpg/credit}}<br/>|}}Base structure of all cephalospori...) |
imported>David E. Volk mNo edit summary |
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[[Image:Cephalosporin base.jpg|right|thumb|250px|{{#ifexist:Template:Cephalosporin base.jpg/credit|{{Cephalosporin base.jpg/credit}}<br/>|}}Base structure of all cephalosporins.]] | [[Image:Cephalosporin base.jpg|right|thumb|250px|{{#ifexist:Template:Cephalosporin base.jpg/credit|{{Cephalosporin base.jpg/credit}}<br/>|}}Base structure of all cephalosporins.]] | ||
'''cephalosporins''' are a class of [[antibiotic]] compounds sharing a common base structure, 7-aminocephalosporanic acid (7-ACA), that was derived from the first cephalosporin, [[ | '''cephalosporins''' are a class of [[antibiotic]] compounds sharing a common base structure, 7-aminocephalosporanic acid (7-ACA), that was derived from the first cephalosporin discovered, [[cephalosporin C]]. [[Penicillin]]s are very similar, although they contain a five-membered ring in place of the six-membered ring present in the cephalosporin. The activity of cephalosporins, penicillins, and some other antibiotics are due to the presence of a [[beta-lactam]], which binds irreversibly, via acylation, to penicillin-binding proteins, thereby inhibiting the peptidogycan layer of bacterial cell wall synthesis. Cephalosporins are often made semisynthetically. | ||
Revision as of 10:32, 29 April 2008
cephalosporins are a class of antibiotic compounds sharing a common base structure, 7-aminocephalosporanic acid (7-ACA), that was derived from the first cephalosporin discovered, cephalosporin C. Penicillins are very similar, although they contain a five-membered ring in place of the six-membered ring present in the cephalosporin. The activity of cephalosporins, penicillins, and some other antibiotics are due to the presence of a beta-lactam, which binds irreversibly, via acylation, to penicillin-binding proteins, thereby inhibiting the peptidogycan layer of bacterial cell wall synthesis. Cephalosporins are often made semisynthetically.