Chronic kidney disease: Difference between revisions
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Chronic kidney disease is defined as "kidney damage or glomerular filtration rate (GFR) <60 mL/min/1.73 m(2) for 3 months or more, irrespective of cause. Kidney damage in many kidney diseases can be ascertained by the presence of albuminuria, defined as albumin-to-creatinine ratio >30 mg/g in two of three spot urine specimens."<ref name="pmid15882252">{{cite journal |author=Levey AS, Eckardt KU, Tsukamoto Y, ''et al'' |title=Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO) |journal=Kidney Int. |volume=67 |issue=6 |pages=2089–100 |year=2005 |pmid=15882252 |doi=10.1111/j.1523-1755.2005.00365.x}}</ref> | {{subpages}} | ||
'''Chronic kidney disease''' is defined as "kidney damage or glomerular filtration rate (GFR) <60 mL/min/1.73 m(2) for 3 months or more, irrespective of cause. Kidney damage in many kidney diseases can be ascertained by the presence of albuminuria, defined as albumin-to-creatinine ratio >30 mg/g in two of three spot urine specimens."<ref name="pmid15882252">{{cite journal |author=Levey AS, Eckardt KU, Tsukamoto Y, ''et al'' |title=Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO) |journal=Kidney Int. |volume=67 |issue=6 |pages=2089–100 |year=2005 |pmid=15882252 |doi=10.1111/j.1523-1755.2005.00365.x}}</ref> | |||
==Classification== | ==Classification== | ||
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==External links== | ==External links== | ||
* [[http://www.nkdep.nih.gov/professionals/gfr_calculators/ National Kidney Disease Education Program - GFR Calculators]] | * [[http://www.nkdep.nih.gov/professionals/gfr_calculators/ National Kidney Disease Education Program - GFR Calculators]] | ||
Revision as of 21:12, 20 December 2007
Chronic kidney disease is defined as "kidney damage or glomerular filtration rate (GFR) <60 mL/min/1.73 m(2) for 3 months or more, irrespective of cause. Kidney damage in many kidney diseases can be ascertained by the presence of albuminuria, defined as albumin-to-creatinine ratio >30 mg/g in two of three spot urine specimens."[1]
Classification
There are five stages:[1]
- Stage 1 - glomerular filtration rate is 90 ml/min/1.73 m2 or more
- Stage 2 - glomerular filtration rate is 60-89 ml/min/1.73 m2
- Stage 3 - glomerular filtration rate is 30-59 ml/min/1.73 m2
- Stage 4 - glomerular filtration rate is 15-29 ml/min/1.73 m2
- Stage 5 - glomerular filtration rate is less than 15 ml/min/1.73 m2 or on dialysis
Signs and symptoms
Uremia, "the illness accompanying kidney failure", may have subtle manifestations when the glomerular filtration rate falls below 60 ml/min/1.73 m2 [2]
References
- ↑ 1.0 1.1 Levey AS, Eckardt KU, Tsukamoto Y, et al (2005). "Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO)". Kidney Int. 67 (6): 2089–100. DOI:10.1111/j.1523-1755.2005.00365.x. PMID 15882252. Research Blogging.
- ↑ Meyer TW, Hostetter TH (2007). "Uremia". N. Engl. J. Med. 357 (13): 1316–25. DOI:10.1056/NEJMra071313. PMID 17898101. Research Blogging.