Sulfasalazine

(CC) Image: David E. Volk
Structure of Sulfasalazine.

Sulfasalazine (SSZ), also called sulphasalazine and sulfasalazin, is a drug used in the treatment of inflammatory bowel disease. Its official IUPAC name is (3E)-6-oxo-3-[[4-(pyridin-2-ylsulfamoyl)phenyl]hydrazinylidene]cyclohexa-1,4-diene-1-carboxylic acid and its chemical formula is C₁₈H₁₄N₄O₅S . Its effects are thought to be due to its breakdown product, 5-aminosalicylic acid (see mesalamine), which is released into the colon. It is also used to treat rheumatoid arthritis

brand names

• Accucol
• Alti-Sulfasalazine
• Asulfidine
• Azlufidine EN-Tabs
• Azopyrin
• Azopyrine
• Azulfidine
• Azulfidine EN-Tabs
• Benzosulfa
• Colo-Pleon
• PMS-Sulfasalazine
• Pms-Sulfasalazine E.C.
• Reupirin
• Rorasul
• S.A.S. Enteric-500
• Salazopiridazin
• Salazopyridin
• Salazopyrin
• Salazopyrin EN-Tabs
• Salazosulfapyridin
• Salazosulfapyridine
• Salicylazosulfapyridine
• Salisulf
• Sulcolon
• W-T Sasp Oral

External Links

The most up-to-date information about Sulfasalazine and other drugs can be found at the following sites.

• Sulfasalazine - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Sulfasalazine - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
• Sulfasalazine - Detailed information from DrugBank.