User:David E. Volk

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[edit intro]
Dave playing a Michael Kelly Dragonfly acoustic base at the Stingaree Music Festival

Hourglass drawing.svg Where David lives it is approximately: 22:14

All truth passes through three stages:

  • First, it is ridiculed.
  • Second, it is violently opposed.
  • Third, it is accepted as being self-evident
Arthur Schopenhauer (1788-1860)


Biography

David E. Volk holds a bachelors degree in mathematics and physics from Minot State (ND) University, and a Ph.D (1995) in physical organic chemistry from North Dakota State University. He completed a post-doctoral fellowship at Duke University Medical Center under Leonard Spicer, was a research scientist at the University of Texas Medical Branch for 12 years, and is currently an Assistant Professor (faculty page) in the Center for Proteomics and Systems Biology at the Brown Foundation Institute for Molecular Medicine, UT Health Science Center Houston.

For much of his career, Dr. Volk's work has used biophysical techniques, such as NMR Spectroscopy and Quantum mechanics, to investigate the structures carcinogen-adducted DNA, proteins and aptamers. Past studies involved solving the structures of the envelope protein domain III of several flaviviruses including West Nile, Yellow fever, Omsk Hemorhaggic Fever and Dengue fever viruses, the S100P protein, glucocorticoid receptor protein, and the VPg protein of poliovirus. Other studies involved both structure and quantum mechanics studies of damaged DNA, such as oxidized DNA or carcinogen-adducted DNA, and DNA aptamers and thioaptamers. His most recent work focuses on metabonomics, proteomics, bioinformatics, and thioaptamer library designs.

Visit his faculty page or publication list for more information.

Chemistry / Health Sciences Articles I Started -part 1

  1. Abacavir
  2. Acetaldehyde
  3. Acetaminophen
  4. Acetic acid
  5. Acetone
  6. Acid
  7. Acyclovir
  8. Alanine
  9. Aldosterone
  10. Amikacin
  11. Aminoglycoside
  12. Ampicillin
  13. Amprenavir
  14. Amoxicillin
  15. Androstenedione
  16. Anion
  17. Antiviral drug
  18. Arginine
  19. Aristolochic acid
  20. Arthralgia
  21. Arthrodynia
  22. Aspartic acid
  23. Asparagine
  24. Atazanavir (AZT)
  25. Atorvastatin (Lipitor)
  26. Azathioprine
  27. Azlocillin
  28. Azole
  29. Bioinformatics
  30. Boron
  31. Boyle's law
  32. Carbenicillin
  33. Carboxylic acid
  34. Carnitine
  35. Cefaclor
  36. Cefadroxil
  37. Cefalotin
  38. Cefazolin
  39. Cefepime
  40. Cerivastatin
  41. Chemistry style guide
  42. Chorismate
  43. Cidofovir
  44. Cinoxacin
  45. Ciprofloxacin
  46. Clofibrate
  47. Cloxacillin
  48. Colestipol
  49. Cortisol
  50. Cross product
  51. Cysteine
  52. Cystine
  53. Diazinon
  54. DEET
  55. Delavirdine
  56. Detergent
  57. Deuterium
  58. Dicloxacillin
  59. Didanosine

  1. Econazole
  2. Efavirenz
  3. Enantiomer
  4. Entecavir
  5. Eplerenone
  6. Ester
  7. Estradiol
  8. Estrogen
  9. Ether
  10. Ezetimibe
  11. Famciclovir
  12. Fenofibrate
  13. Folic acid
  14. Foscarnet
  15. Fosfomycin
  16. Flavivirus
  17. Flucloxacillin
  18. Fluvastatin
  19. Fuming sulfuric acid
  20. GABA
  21. Ganciclovir
  22. Gemfibrozil
  23. Glucose
  24. Glutamic acid
  25. Glutamine
  26. Hetacillin
  27. Hexose
  28. Hippurate
  29. Histidine
  30. Hydrocortisone
  31. Hydrophilic
  32. HMG CoA
  33. Hydrogen/Isotopes
  34. Ideal gas law
  35. Idoxuridine
  36. Indinavir
  37. Iron/Isotopes
  38. Isoleucine
  39. Ketoconazole
  40. Lamivudine
  41. Leflunomide
  42. Leucine
  43. Lewis acid
  44. Lewis acid-base theory
  45. List of NMR experiments
  46. Lovastatin
  47. Lysine
  48. Mesalamine
  49. Methionine
  50. Methotrexate
  51. Mevalonate
  52. Mevastatin
  53. Mezlocillin
  54. Midodrine
  55. Minocycline
  56. NADPH

Chemistry / Health Sciences Articles I Started -part 2

  1. Nelfinavir
  2. Netilmicin
  3. Nitroglycerin
  4. Nitromethane
  5. Neuralgia
  6. Oseltamivir
  7. Oxacillin
  8. NMR active elements
  9. Penciclovir
  10. Penicillin G
  11. Penicillin V
  12. Phenylalanine
  13. Phosphate
  14. Phosphoric acid
  15. Phosphorus
  16. Piperacillin
  17. Pravastatin
  18. Prednisone
  19. Prednisolone
  20. Progesterone
  21. Proline
  22. Protease inhibitor
  23. Protein structure
  24. Rhabdomyolysis
  25. Ribavirin
  26. Rimantadine
  27. Ritonavir
  28. Rosuvastatin (Crestor)
  29. Saquinavir
  30. Serine
  31. Simvastatin
  32. Spironolactone
  33. Stavudine
  34. Stent
  35. Steroid
  36. Streptomycin
  37. Sulfasalazine
  38. Sulfur dioxide
  39. Sulfuric acid
  40. Tenofovir
  41. Testosterone
  42. Thioaptamer
  43. Tioconazole
  44. Tipranavir
  45. Threonine
  46. Triazole
  47. Tryptophan
  48. Tyrosine
  49. Valine
  50. Vidarabine
  51. Voriconazole
  52. Warfarin
  53. West Nile virus
  54. Zalcitabine
  55. Zanamivir
  56. Zidovudine


Music Articles I Created

  1. Band of Heathens
  2. Cover band
  3. Eliza Gilkyson
  4. Gurf Morlix
  5. Lightnin' Hopkins
  6. Liz and Lincoln
  7. Lucinda Williams
  8. Rex Bell
  9. Rex Bell/Discography
  10. REO Speedwagon
  11. REO Speedwagon/Discography
  12. Rush
  13. Singer-songwriter
  14. Hayes Carll
  15. Scott Nolan
  16. Stingaree Music Festival cluster
  17. Townes Van Zandt
  18. Townes Van Zandt/Discography (this was work!)

Other Articles I Created

  1. Carne gasada - a savory Mexican stew
  2. Chateau de Mores
  3. Chili-mac (vegetarian)
  4. Enchilada sauce - both red and green
  5. Galveston County Daily News
  6. Kim Komando
  7. Kirchhoff's current law
  8. Kirchhoff's voltage law
  9. Law of cosines
  10. Law of sines
  11. Judge Susan Criss of Galveston, County, Texas
  12. Texas Hold 'Em

Areas of Expertise

  1. Nuclear Magnetic Resonance (NMR) spectroscopy
    1. Protein NMR Structures
      1. West Nile virus ED3
      2. Omsk Hemorhagic fever ED3
      3. Dengue 4 virus
      4. Yellow fever virus
    2. DNA Structures
      1. Benzo[a]pyrene-adducted (carcinogenic) DNA
      2. Oxidatively Damaged DNA
      3. Thioaptamer DNA
    3. Metabonomics/Metabolomics
  2. Quantum Mechanics
    1. DNA:DNA Interactions
    2. DNA:Metal Interactions
  3. Lewis Acid Chemistry
    1. AlCl3 and Et2AlCl mediated ring opening reactions
    2. SnCl4 mediated ring opening reactions
  4. Protein Expression & Purification
  5. Molecular Mechanics

Areas of General Competence

  • Physical/Organic Chemistry
  • Molecular Biology
  • Structural Biology
  • Physics
  • Mathematics
  • Computer Programming
    • Pascal
    • Perl
    • C++
  • MAcromolecular Purification Methods
  • Surface Plasmon Resonance (Biacore)
  • Binding thermodynamics and kinetics


Hobbies

  • Bass Guitar
  • Texas Holdem'
  • Bird Watching